BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0003.p (389 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYM4.1 D8IYM4_HERSS Bifunctional: glutathione-dependent formal... 744 0.0 E6QUU5.1 E6QUU5_9ZZZZ Alcohol dehydrogenase class III/glutathion... 696 0.0 F1W194.1 F1W194_9BURK S-(Hydroxymethyl)glutathione dehydrogenase 694 0.0 A9HWH4.1 A9HWH4_BORPD Alcohol dehydrogenase class III EC=1.1.1.1 682 0.0 Q0K1Y8.1 Q0K1Y8_CUPNH Alcohol dehydrogenase, class III EC=1.1.1.284 682 0.0 >D8IYM4.1 D8IYM4_HERSS Bifunctional: glutathione-dependent formaldehyde dehydrogenase and alcohol dehydrogenase class III oxidoreductase protein EC=1.1.1.1 EC=1.1.1.284 Length = 368 Score = 744 bits (1922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/368 (98%), Positives = 365/368 (99%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKT+AAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL Sbjct: 1 MKTRAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIR+TQGRGLMPD Sbjct: 61 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRATQGRGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIR DAPFDKVCYIGCGVTTGVGAVLF Sbjct: 121 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIRSDAPFDKVCYIGCGVTTGVGAVLF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQAA+MVGANKIIGVDLNP REAMARKFGMTDFINPKD Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQAAKMVGANKIIGVDLNPAREAMARKFGMTDFINPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVDAIIG+TDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF Sbjct: 241 VPNVVDAIIGMTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE Sbjct: 301 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 360 Query: 382 SIRSVVEF 389 SIRSVVEF Sbjct: 361 SIRSVVEF 368 >E6QUU5.1 E6QUU5_9ZZZZ Alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase EC=1.1.1.1 EC=1.1.1.284 Length = 368 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/368 (89%), Positives = 353/368 (95%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAAVAWQAG PLTIEEV+L GP+AGEVLVEIKATGICHTDYYTL+GADPEG+FPAIL Sbjct: 1 MKTKAAVAWQAGAPLTIEEVDLDGPRAGEVLVEIKATGICHTDYYTLTGADPEGLFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+VVDVGPGV SLKKDDHVIPLYTPECR+CK+CLS+KTNLCQAIRSTQGRGLMPD Sbjct: 61 GHEGAGIVVDVGPGVTSLKKDDHVIPLYTPECRQCKYCLSRKTNLCQAIRSTQGRGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 TSRFS+DGKP+FHYMGTSTFSNYIVVPEIALAKIREDAPFDK CYIGCGVTTGVGAV+F Sbjct: 121 GTSRFSIDGKPIFHYMGTSTFSNYIVVPEIALAKIREDAPFDKACYIGCGVTTGVGAVVF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 +AKVEAGANVVVFGLGGIGLNVIQAA+MVGANKIIGVD+NP R AMARKFGMTDF+NP + Sbjct: 181 SAKVEAGANVVVFGLGGIGLNVIQAAKMVGANKIIGVDINPRRIAMARKFGMTDFVNPNE 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 ++NVVD I+ LTDGGADYSFECIGN TTMRQ+LECCHKGWGQS IIGVAAAGQEISTRPF Sbjct: 241 IANVVDHIVQLTDGGADYSFECIGNVTTMRQALECCHKGWGQSFIIGVAAAGQEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVPKIVDWYM+GKLNIDDLITH LPLERINEGFDLMKSGE Sbjct: 301 QLVTGREWKGSAFGGARGRTDVPKIVDWYMDGKLNIDDLITHTLPLERINEGFDLMKSGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368 >F1W194.1 F1W194_9BURK S-(Hydroxymethyl)glutathione dehydrogenase Length = 368 Score = 694 bits (1790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/368 (89%), Positives = 353/368 (95%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAAVAWQAG+PLTIEEVELGGP+AGEVLVE+KATGICHTDYYTLSGADPEG+FPAIL Sbjct: 1 MKTKAAVAWQAGRPLTIEEVELGGPRAGEVLVELKATGICHTDYYTLSGADPEGLFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+VVDVGP VKS++KDDHVIPLYTPECR+CKFCLSQKTNLCQ+IRSTQG+GLMPD Sbjct: 61 GHEGAGIVVDVGPDVKSIRKDDHVIPLYTPECRQCKFCLSQKTNLCQSIRSTQGQGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAV+F Sbjct: 121 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVIF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVE GA VVVFGLGGIGLNVIQAA+MVGA+KIIG+DLNP REAMARKFGMTDFINPKD Sbjct: 181 TAKVEFGATVVVFGLGGIGLNVIQAAKMVGASKIIGIDLNPAREAMARKFGMTDFINPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVD I+ LTDGGADYSFECIGNT MRQ+LEC HKGWGQ+I+IGVA AG EISTRPF Sbjct: 241 VENVVDRIVELTDGGADYSFECIGNTKVMRQALECTHKGWGQAIVIGVADAGAEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVPKIVD YM+GKLNIDDLITH+LPLERINEGFDLMK+GE Sbjct: 301 QLVTGREWKGSAFGGARGRTDVPKIVDMYMDGKLNIDDLITHRLPLERINEGFDLMKAGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368 >A9HWH4.1 A9HWH4_BORPD Alcohol dehydrogenase class III EC=1.1.1.1 Length = 368 Score = 682 bits (1761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/368 (88%), Positives = 349/368 (94%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAAVAW+AG PLTIEEV+L GP+AGEVL+E+KATGICHTDYYTLSGADPEG+FPAIL Sbjct: 1 MKTKAAVAWKAGAPLTIEEVDLEGPRAGEVLIEVKATGICHTDYYTLSGADPEGLFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+VVDVG GV SLKK DHVIPLYTPECR+CKFCLS+KTNLCQAIR+TQG+GLMPD Sbjct: 61 GHEGAGIVVDVGAGVTSLKKGDHVIPLYTPECRQCKFCLSRKTNLCQAIRATQGKGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFSL+GKPL HYMGTSTF+N+IVVPEIA+AK+REDAPFDK+CYIGCGVTTGVGAV++ Sbjct: 121 ATSRFSLNGKPLLHYMGTSTFANHIVVPEIAVAKVREDAPFDKICYIGCGVTTGVGAVVY 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQ ARMVGA+KIIGVDLNPGREAMARKFGMT F+NPKD Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQGARMVGADKIIGVDLNPGREAMARKFGMTHFVNPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVD I+ LTDGGADYSFECIGNT MRQ+LECCHKGWGQSIIIGVA AG EISTRPF Sbjct: 241 VDNVVDHIVQLTDGGADYSFECIGNTQVMRQALECCHKGWGQSIIIGVAEAGAEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVPKIVDWYMEGK+NIDDLITH LPLERINEGFDLMK GE Sbjct: 301 QLVTGRQWKGSAFGGARGRTDVPKIVDWYMEGKINIDDLITHTLPLERINEGFDLMKRGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368 >Q0K1Y8.1 Q0K1Y8_CUPNH Alcohol dehydrogenase, class III EC=1.1.1.284 Length = 368 Score = 682 bits (1760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/368 (88%), Positives = 348/368 (94%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAA+AW+AG PLTIE+V+L GP+AGEVLVE+KATGICHTDYYTLSGADPEGIFPAIL Sbjct: 1 MKTKAAIAWKAGAPLTIEDVDLDGPRAGEVLVEVKATGICHTDYYTLSGADPEGIFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+V DVGPGV SLK DHVIPLYTPECR+CKFCLS+KTNLCQAIR+TQG+GLMPD Sbjct: 61 GHEGAGIVTDVGPGVTSLKPGDHVIPLYTPECRQCKFCLSRKTNLCQAIRATQGKGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 TSRFS+DGKP+FHYMGTSTF+N+IVVPEIALAKIR DAPFDKVCYIGCGVTTGVGAVLF Sbjct: 121 GTSRFSIDGKPIFHYMGTSTFANHIVVPEIALAKIRPDAPFDKVCYIGCGVTTGVGAVLF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQAA+MVGA+KIIGVDLNPGREAMARKFGMT FINPKD Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQAAKMVGADKIIGVDLNPGREAMARKFGMTHFINPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVD II LTDGGADYSFECIGNT MRQ+LECCHKGWG+SIIIGVA AG EISTRPF Sbjct: 241 VENVVDHIIQLTDGGADYSFECIGNTQVMRQALECCHKGWGKSIIIGVAEAGAEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVP+IVDWYMEGKLNIDDLITH LPLERINEGFDLMK GE Sbjct: 301 QLVTGREWKGSAFGGARGRTDVPRIVDWYMEGKLNIDDLITHTLPLERINEGFDLMKRGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368