BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0046.p (349 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value F1VZF2.1 F1VZF2_9BURK Multi-sensor signal transduction histidine... 321 1e-85 D3EE87.1 D3EE87_GEOS4 Integral membrane sensor hybrid histidine ... 122 1e-25 F0F399.1 F0F399_9BACT Two component system sensor histidine kina... 120 4e-25 A0YTY5.1 A0YTY5_LYNSP Two-component sensor histidine kinase 118 1e-24 E0IB89.1 E0IB89_9BACL Integral membrane sensor hybrid histidine ... 118 1e-24 >F1VZF2.1 F1VZF2_9BURK Multi-sensor signal transduction histidine kinase Length = 259 Score = 321 bits (822), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 152/259 (58%), Positives = 200/259 (77%) Query: 87 LQGKPFHVINLVFDSAIGLAVQTFSVNRALEVQRRREEYLSFIAHDLRTPLNAVALASKV 146 +QGKPFH++N V D AIG AVQ+++ RAL+VQ RRE+YL+F+AHDLRTPL+A++LA++V Sbjct: 1 MQGKPFHILNQVLDGAIGAAVQSYATQRALDVQTRREDYLAFVAHDLRTPLSAISLAARV 60 Query: 147 LESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNIDLWPL 206 LE ++ + +M+K L RNVQ +S LVA +++E+ N++T SGV L+ R+ DLWPL Sbjct: 61 LELSVHDPAKSKQTGQMLKTLHRNVQHLSSLVANILDESINLQTGSGVTLKCRHFDLWPL 120 Query: 207 VESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEVVIGA 266 VE+++ DLNPVAGTGSTRLLN+VPED IYADANLLRR++QNLIANAI +TP G+V I A Sbjct: 121 VEALIIDLNPVAGTGSTRLLNEVPEDQTIYADANLLRRILQNLIANAIHYTPHGDVTISA 180 Query: 267 APTLDGAGIECWVSDNGMGISKDRLALIFEKFETETKDHGGLGLGLAIFKTFVEAHEGSF 326 P+ DG GI C VSD G GI+ D L +F+KFE++ + G+GLGLAI KTFVEAH G+ Sbjct: 181 GPSGDGLGIACTVSDTGSGIAADLLDKVFDKFESDPANGNGMGLGLAIVKTFVEAHGGTV 240 Query: 327 DVVSEPGKGSRFSFILPNR 345 V SEP +GS F LP+R Sbjct: 241 RVDSEPDRGSVFRITLPDR 259 >D3EE87.1 D3EE87_GEOS4 Integral membrane sensor hybrid histidine kinase Length = 1017 Score = 122 bits (305), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 87/265 (32%), Positives = 146/265 (55%), Gaps = 19/265 (7%) Query: 92 FHVINLVFDSAIGLAVQT----FSVNRA----LEVQRRREEYLSFIAHDLRTPLNAV-AL 142 F V+ VF A+ L++++ F V R L + + ++E+L+ +H+LRTPL+ + L Sbjct: 362 FGVLGFVFLQALLLSMKSSRAFFQVERLSERLLTLDKLKDEFLAKTSHELRTPLHGIIGL 421 Query: 143 ASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNID 202 A +++ + G + ++++++ + Q ++ LV +++ + E G+ L N+ Sbjct: 422 ADALIDGSSGKLPSP--VIDLLRLMKVSGQRLAHLVNDILDFSKLKHQEIGLVLVTVNLR 479 Query: 203 LWPLVESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEV 262 L VE + LNP+A RL + +P+D+ + AD N L++++ NLI NAI +T G V Sbjct: 480 L--AVELTLQVLNPLAEKKGLRLSHQLPDDMYVMADENRLQQILHNLIGNAIAYTETGTV 537 Query: 263 VIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEKFET----ETKDHGGLGLGLAIFKTF 318 + A L G + ++D+G+GIS+ L IFE FE + GG G+GL+I K Sbjct: 538 TV-TAKRLQGQ-VSVQITDSGIGISEADLDRIFESFEQINPLDRSQQGGTGIGLSITKKL 595 Query: 319 VEAHEGSFDVVSEPGKGSRFSFILP 343 VE H G V S G+GS FSF LP Sbjct: 596 VELHGGRIGVTSGVGEGSTFSFTLP 620 >F0F399.1 F0F399_9BACT Two component system sensor histidine kinase/response regulator hybrid Length = 878 Score = 120 bits (300), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 82/259 (31%), Positives = 137/259 (52%), Gaps = 10/259 (3%) Query: 92 FHVINLVFDSAIGLAVQTFSVNRALEVQRR--REEYLSFIAHDLRTPLNAVALASKVLES 149 F VI ++ + A +T + R +E + + ++ + I+H+LRTPL +A +E Sbjct: 340 FSVIIILLVGIMVYAYRTTVMRRHIEEEATAAKLQFFTNISHELRTPLTLIA---DPVEY 396 Query: 150 TLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESG-VKLERRNIDLWPLVE 208 + N P+ M++++QRNV +S LV++++ D K ++G ++L + DL + Sbjct: 397 IIHDPNLSPQQRGMLQIVQRNVAVLSRLVSEIL---DFRKVQNGKMQLHLSDFDLSECMR 453 Query: 209 SMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEVVIGAAP 268 + + A L VPE + + AD + L R+ NL++NA+ +TP+G IG A Sbjct: 454 QWLGLFDTSARKKHITLQLHVPESIPMRADRDKLERICYNLLSNAMKYTPEGGC-IGFAA 512 Query: 269 TLDGAGIECWVSDNGMGISKDRLALIFEKFETETKDHGGLGLGLAIFKTFVEAHEGSFDV 328 +++ + VSDNG GI++D L +F++F G G+GLA+ K F E H G V Sbjct: 513 SVEADKVGIMVSDNGCGIAQDDLPYVFDRFYQAGNAGHGTGIGLALVKAFAELHHGQATV 572 Query: 329 VSEPGKGSRFSFILPNRPE 347 SE GKG F +P R E Sbjct: 573 ESEEGKGCTFVVSMPLRQE 591 >A0YTY5.1 A0YTY5_LYNSP Two-component sensor histidine kinase Length = 1012 Score = 118 bits (296), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 78/233 (33%), Positives = 131/233 (56%), Gaps = 16/233 (6%) Query: 122 REEYLSFIAHDLRTPLNAV-ALASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAK 180 ++E+L+ +H+LRTPLN + +A +++ G Q +D + + ++ + +S LV Sbjct: 358 KDEFLANTSHELRTPLNGIIGIAESLIDGATG-QLSDLTQSNLAMIVSSG-RRLSSLVND 415 Query: 181 VIEENDNMKTE-SGVKLERRNIDLWPLVESMVYDLNPVAGTGSTRLLNDV-PEDLVIYAD 238 V+ D K S + L+ + +DL+ + + ++ P+ G + +L+N + PE + AD Sbjct: 416 VL---DFSKIRYSNIDLQLKPVDLYTITDLVITLSQPLVGKKNLQLINSINPESPAVQAD 472 Query: 239 ANLLRRMMQNLIANAITHTPQGEVVIGAAPT----LDGAGIECWVSDNGMGISKDRLALI 294 N L++++ NL+ NAI T G+V I A D ++ ++D G+GIS+D+ I Sbjct: 473 ENRLQQILHNLVGNAIKFTAAGQVEILAKKVDNLESDQEFLKIVIADTGIGISEDKFEQI 532 Query: 295 FEKFE----TETKDHGGLGLGLAIFKTFVEAHEGSFDVVSEPGKGSRFSFILP 343 FE FE T +++GG GLGLAI K VE G +V S G+GS+FSF LP Sbjct: 533 FESFEQASGTTAREYGGTGLGLAITKQLVELQGGKIEVFSRLGEGSQFSFTLP 585 >E0IB89.1 E0IB89_9BACL Integral membrane sensor hybrid histidine kinase Length = 1088 Score = 118 bits (296), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 129/239 (53%), Gaps = 10/239 (4%) Query: 114 RALEVQRRREEYLSFIAHDLRTPLNAV-ALASKVLESTLGAQNADPRAARMIKVLQRNVQ 172 R L + + ++E+L+ +H+LRTPL+ + L +L+ G++ + + ++++ + Q Sbjct: 425 RLLSLDKLKDEFLARTSHELRTPLHGIIGLTESLLDGPAGSRLSAEENGHL-QLIRSSGQ 483 Query: 173 SMSGLVAKVIEENDNMKTESGVKLERRNIDLWPLVESMVYDLNPVAGTGSTRLLNDVPED 232 ++ LV +++ + E ++L I++ +VE +++ L P+A L+N+VP Sbjct: 484 RLAHLVNDILDFSKLRNRE--IQLHPVTINVHQIVELVLHLLRPLAEGKGLLLINEVPPA 541 Query: 233 LVIYADANLLRRMMQNLIANAITHTPQGEVVIGAAPTLDGAGIECWVSDNGMGISKDRLA 292 L + AD N L +M+ NL+ NA T QG VVI A I + D G+GI+++ L Sbjct: 542 LQVRADENRLHQMLHNLVGNATKFTLQGHVVISARK--QARQITINIKDTGIGIAQESLG 599 Query: 293 LIFEKFE----TETKDHGGLGLGLAIFKTFVEAHEGSFDVVSEPGKGSRFSFILPNRPE 347 +IFE FE T GG G+GL+I K VE H G S PG GS FSF LP E Sbjct: 600 VIFESFEQLDPTTNSRFGGTGIGLSITKKLVELHGGRIWAESTPGLGSSFSFTLPEASE 658