BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0275.p (286 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4GAF0.1 DCUP_HERAR Uroporphyrinogen decarboxylase EC=4.1.1.37 484 e-135 A6T450.1 DCUP_JANMA Uroporphyrinogen decarboxylase EC=4.1.1.37 482 e-134 D8IVL7.1 D8IVL7_HERSS Uroporphyrinogen decarboxylase EC=4.1.1.37 476 e-132 F1W2H4.1 F1W2H4_9BURK Uroporphyrinogen III decarboxylase 468 e-130 Q1LHL3.1 DCUP_RALME Uroporphyrinogen decarboxylase EC=4.1.1.37 424 e-116 >A4GAF0.1 DCUP_HERAR Uroporphyrinogen decarboxylase EC=4.1.1.37 Length = 360 Score = 484 bits (1246), Expect = e-135, Method: Compositional matrix adjust. Identities = 228/259 (88%), Positives = 246/259 (94%) Query: 9 FAPLKNDTFLRALLRQPTNYTPLWLMRQAGRYLPEYRATRARAGSFLGLAKNPDYATEVT 68 FAPLKNDTFLRALLRQPT+YTP+W+MRQAGRYLPEYRATR RAGSFLGLAKNPDYATEVT Sbjct: 5 FAPLKNDTFLRALLRQPTDYTPMWMMRQAGRYLPEYRATRTRAGSFLGLAKNPDYATEVT 64 Query: 69 LQPLERYPLDAAILFSDILTVPDAMGLGLFFADGEGPKFERPLRDEKAVLALQAPQLDSL 128 LQPL+RY LDAAILFSDILTVPDAMGLGL+F DGEGPKFERPLRDEKAV AL+ P+LDSL Sbjct: 65 LQPLDRYDLDAAILFSDILTVPDAMGLGLYFVDGEGPKFERPLRDEKAVQALKVPELDSL 124 Query: 129 QYVFDAVTQIRTELDGRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKTMLYDRPDLMHHI 188 QYVFDAVTQIRTEL GRVPLIGFSGSPWTLACYMVEGGGSDDFRTVK MLY+RPDLMHHI Sbjct: 125 QYVFDAVTQIRTELKGRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKAMLYNRPDLMHHI 184 Query: 189 LRTNAAAVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQAFSLHYMREVMRQLKRDKDGV 248 L+TNA VAAYLNAQIDAGAQAVM+FDTWGGALADG+YQ FSLHYMREVM+ +K +K+GV Sbjct: 185 LQTNAITVAAYLNAQIDAGAQAVMMFDTWGGALADGIYQQFSLHYMREVMKHVKTEKEGV 244 Query: 249 KIPAIVFTKGGGLWLEQIA 267 +IP+IVFTKGGGLWL +IA Sbjct: 245 RIPSIVFTKGGGLWLNEIA 263 >A6T450.1 DCUP_JANMA Uroporphyrinogen decarboxylase EC=4.1.1.37 Length = 360 Score = 482 bits (1240), Expect = e-134, Method: Compositional matrix adjust. Identities = 228/261 (87%), Positives = 247/261 (94%) Query: 7 SQFAPLKNDTFLRALLRQPTNYTPLWLMRQAGRYLPEYRATRARAGSFLGLAKNPDYATE 66 +QFAPL+NDTFLRALLRQPT YTPLWLMRQAGRYLPEYRATRARAGSFLGLAKNPD+ATE Sbjct: 3 TQFAPLQNDTFLRALLRQPTEYTPLWLMRQAGRYLPEYRATRARAGSFLGLAKNPDFATE 62 Query: 67 VTLQPLERYPLDAAILFSDILTVPDAMGLGLFFADGEGPKFERPLRDEKAVLALQAPQLD 126 VTLQPL+RY LDAAILFSDILTVPDAMGLGL+F +GEGPKFERPLRDEKAV AL+ P+L Sbjct: 63 VTLQPLDRYKLDAAILFSDILTVPDAMGLGLYFIEGEGPKFERPLRDEKAVQALKVPELG 122 Query: 127 SLQYVFDAVTQIRTELDGRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKTMLYDRPDLMH 186 SLQYVFDAVTQIRTEL GRVPLIGF+GSPWTLACYMVEGGGSDDFRTVK MLY+RPDLMH Sbjct: 123 SLQYVFDAVTQIRTELKGRVPLIGFTGSPWTLACYMVEGGGSDDFRTVKAMLYNRPDLMH 182 Query: 187 HILRTNAAAVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQAFSLHYMREVMRQLKRDKD 246 HIL+TNA VAAYLNAQIDAGAQAVM+FDTWGGALADG YQ FSLHYMREVM+ +K +KD Sbjct: 183 HILQTNALTVAAYLNAQIDAGAQAVMMFDTWGGALADGAYQQFSLHYMREVMKHVKTEKD 242 Query: 247 GVKIPAIVFTKGGGLWLEQIA 267 GV+IP+IVFTKGGGLWL++IA Sbjct: 243 GVRIPSIVFTKGGGLWLKEIA 263 >D8IVL7.1 D8IVL7_HERSS Uroporphyrinogen decarboxylase EC=4.1.1.37 Length = 364 Score = 476 bits (1225), Expect = e-132, Method: Compositional matrix adjust. Identities = 230/267 (86%), Positives = 245/267 (91%) Query: 1 MSQLSTSQFAPLKNDTFLRALLRQPTNYTPLWLMRQAGRYLPEYRATRARAGSFLGLAKN 60 MS S S FAPLKNDTFLRALLRQPT+YTP+WLMRQAGRYLPEYRATRARAGSF+GLA N Sbjct: 1 MSSSSMSTFAPLKNDTFLRALLRQPTDYTPMWLMRQAGRYLPEYRATRARAGSFMGLATN 60 Query: 61 PDYATEVTLQPLERYPLDAAILFSDILTVPDAMGLGLFFADGEGPKFERPLRDEKAVLAL 120 PDYATEVTLQPLERYPLDAAILFSDILTVPDAMGLGL+FA+GEGPKF+RPLRDE AV AL Sbjct: 61 PDYATEVTLQPLERYPLDAAILFSDILTVPDAMGLGLYFAEGEGPKFQRPLRDEAAVKAL 120 Query: 121 QAPQLDSLQYVFDAVTQIRTELDGRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKTMLYD 180 +AP L L YVF AVTQIR ELDGRVPLIGFSGSPWTLACYMVEGGGSDDFR VK+MLY Sbjct: 121 RAPDLGKLDYVFKAVTQIRRELDGRVPLIGFSGSPWTLACYMVEGGGSDDFRLVKSMLYS 180 Query: 181 RPDLMHHILRTNAAAVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQAFSLHYMREVMRQ 240 RPDLMHHILRTNA AVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQ FSL YM++V+ Q Sbjct: 181 RPDLMHHILRTNADAVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQQFSLSYMQQVVSQ 240 Query: 241 LKRDKDGVKIPAIVFTKGGGLWLEQIA 267 LKR++ G ++P IVFTKGGGLWLEQIA Sbjct: 241 LKREQGGQQVPVIVFTKGGGLWLEQIA 267 >F1W2H4.1 F1W2H4_9BURK Uroporphyrinogen III decarboxylase Length = 359 Score = 468 bits (1205), Expect = e-130, Method: Compositional matrix adjust. Identities = 224/262 (85%), Positives = 242/262 (92%) Query: 6 TSQFAPLKNDTFLRALLRQPTNYTPLWLMRQAGRYLPEYRATRARAGSFLGLAKNPDYAT 65 +++FAPLKNDTFLRALLRQPT+YTP+WLMRQAGRYLPEYRATRARAGSFLGLAKNPDYAT Sbjct: 2 STKFAPLKNDTFLRALLRQPTDYTPVWLMRQAGRYLPEYRATRARAGSFLGLAKNPDYAT 61 Query: 66 EVTLQPLERYPLDAAILFSDILTVPDAMGLGLFFADGEGPKFERPLRDEKAVLALQAPQL 125 EVTLQPL+R+PLDAAILFSDILTVPDAMGLGL+FADGEGPKFERPLRDE AV+ALQ P L Sbjct: 62 EVTLQPLDRFPLDAAILFSDILTVPDAMGLGLYFADGEGPKFERPLRDEAAVMALQVPDL 121 Query: 126 DSLQYVFDAVTQIRTELDGRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKTMLYDRPDLM 185 LQYV+DAVTQIRTELDGRVPLIGFSGSPWTLACYMVEGGGSDDFR VK+MLYDRPDLM Sbjct: 122 GDLQYVYDAVTQIRTELDGRVPLIGFSGSPWTLACYMVEGGGSDDFRRVKSMLYDRPDLM 181 Query: 186 HHILRTNAAAVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQAFSLHYMREVMRQLKRDK 245 H IL NA AVA YLNAQI AGAQAVMIFD+WGGALADG YQ FSL YMREV+ QL D+ Sbjct: 182 HRILSINATAVAGYLNAQIAAGAQAVMIFDSWGGALADGAYQKFSLDYMREVVAQLHLDQ 241 Query: 246 DGVKIPAIVFTKGGGLWLEQIA 267 +G ++P IVFTKGGGLWL+QIA Sbjct: 242 EGGRVPCIVFTKGGGLWLDQIA 263 >Q1LHL3.1 DCUP_RALME Uroporphyrinogen decarboxylase EC=4.1.1.37 Length = 367 Score = 424 bits (1089), Expect = e-116, Method: Compositional matrix adjust. Identities = 209/264 (79%), Positives = 227/264 (85%), Gaps = 4/264 (1%) Query: 12 LKNDTFLRALLRQPTNYTPLWLMRQAGRYLPEYRATRARAGSFLGLAKNPDYATEVTLQP 71 L+NDTFLRAL RQPT YTPLWLMRQAGRYLPEY ATRARAGSFLGLAKNP YATEVTLQP Sbjct: 4 LQNDTFLRALRRQPTEYTPLWLMRQAGRYLPEYNATRARAGSFLGLAKNPAYATEVTLQP 63 Query: 72 LERYPLDAAILFSDILTVPDAMGLGLFFADGEGPKFERPLRDEKAVLALQAPQLDSLQYV 131 L+RYPLDAAILFSDILTVPDAMGLGL FA GEGP+F PLR E V L P + SLQYV Sbjct: 64 LDRYPLDAAILFSDILTVPDAMGLGLSFAQGEGPRFAHPLRTEADVAKLAVPDMASLQYV 123 Query: 132 FDAVTQIRTEL--DGR--VPLIGFSGSPWTLACYMVEGGGSDDFRTVKTMLYDRPDLMHH 187 FDAV++IR L DGR VPLIGFSGSPWTLACYMVEGGGSDDFRTVK M+Y RPDLMH Sbjct: 124 FDAVSEIRKALVQDGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKAMMYARPDLMHR 183 Query: 188 ILRTNAAAVAAYLNAQIDAGAQAVMIFDTWGGALADGVYQAFSLHYMREVMRQLKRDKDG 247 IL NA AV+AYLNAQI+AGAQAVM+FDTWGGALADG+YQAFSL YMR+V++ LKR+ DG Sbjct: 184 ILDINATAVSAYLNAQIEAGAQAVMVFDTWGGALADGMYQAFSLAYMRKVLQGLKREHDG 243 Query: 248 VKIPAIVFTKGGGLWLEQIAXSRP 271 +IP IVFTKGGG+WLE+IA P Sbjct: 244 QQIPVIVFTKGGGIWLEEIAGIGP 267