BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0258.p (397 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value E3HPQ0.1 E3HPQ0_ACHXA AMP-binding enzyme family protein 11 503 e-140 E8TZJ3.1 E8TZJ3_ALIDB AMP-dependent synthetase and ligase 390 e-106 Q46MY5.1 Q46MY5_CUPPJ AMP-dependent synthetase and ligase 389 e-106 C1DGA5.1 C1DGA5_AZOVD AMP-dependent synthetase and ligase protein 386 e-105 C5T0Q6.1 C5T0Q6_ACIDE AMP-dependent synthetase and ligase 383 e-104 >E3HPQ0.1 E3HPQ0_ACHXA AMP-binding enzyme family protein 11 Length = 508 Score = 503 bits (1294), Expect = e-140, Method: Compositional matrix adjust. Identities = 244/381 (64%), Positives = 297/381 (77%), Gaps = 2/381 (0%) Query: 11 LKIVDVGTDHYLDAASGPLLDAFPIAADALAWLFYTSGTTGRPKGVMLTHANMVSMAMHF 70 +++VDV + Y AA G L LAWLFYTSGTTG+PKGVML+HANMV M ++F Sbjct: 124 VQLVDVDSARYASAAIGTALPLERRKPQELAWLFYTSGTTGKPKGVMLSHANMVGMCLNF 183 Query: 71 LIDVQPLASDDVLIHVAPMSHGSGLYSVPYFIRGGLQVIPESGGLDEAELFGLLNHYDKA 130 DVQ + D ++HVAP+SHG+GLYS+PY++ G LQ+IP+SGGLDE EL LL HY + Sbjct: 184 YADVQSVQPGDAIVHVAPLSHGAGLYSIPYWLHGALQIIPDSGGLDEDELSALLTHYRRV 243 Query: 131 SLFAAPTIVMRLIQHVRNHTGVTWPGLRCLLVGGAPFYAEDIKSAVQCFGARVAQLYGQG 190 SLFA+PTIV R+++H R G PGLR L+VGGAPFY EDIK AV C+GARVAQ+YGQG Sbjct: 244 SLFASPTIVQRMVRHARQTNGPQ-PGLRTLIVGGAPFYVEDIKDAVACYGARVAQIYGQG 302 Query: 191 ETPMTISALSADLLARAVAADDTAMLVSVGFAQTAIGITIVDADGNPVTAGTPGEVIVRG 250 E+PM+ISALSA +A AVA +D +L SVG+ Q ++ + + A G P AG GEV+V G Sbjct: 303 ESPMSISALSAAQIANAVANNDDILLGSVGYVQASMEVEVRAASGQP-AAGELGEVVVSG 361 Query: 251 PTVMTGYWGNPEATRQTIGGGALRTGDIGLIDERGLLHLKDRSKDVIISGGTNIYPREVE 310 PTVM GYW NP A+ T+ G L TGDIG++DERGLLHLKDRSKDVIISGGTNIYPREVE Sbjct: 362 PTVMQGYWNNPRASADTLADGWLHTGDIGILDERGLLHLKDRSKDVIISGGTNIYPREVE 421 Query: 311 EALLTHPAVEEVSVVGAPDPEWGESVVAFIVCHAGASAGEQELDELCIRTIARFKRPKRY 370 EAL+ H AV+EVSVVG+PDPEWGESV+AF+V GA A EQ+LD+LC+ +IARFKRPKRY Sbjct: 422 EALMRHDAVQEVSVVGSPDPEWGESVLAFVVLKPGARATEQDLDQLCLASIARFKRPKRY 481 Query: 371 VFVEKLPKNGTGKVLKRELQQ 391 VF+++LPKN TGKVLKRELQQ Sbjct: 482 VFLDELPKNSTGKVLKRELQQ 502 >E8TZJ3.1 E8TZJ3_ALIDB AMP-dependent synthetase and ligase Length = 502 Score = 390 bits (1003), Expect = e-106, Method: Compositional matrix adjust. Identities = 200/375 (53%), Positives = 252/375 (67%), Gaps = 2/375 (0%) Query: 16 VGTDHYLDAASGPLLDAFPIAADALAWLFYTSGTTGRPKGVMLTHANMVSMAMHFLIDVQ 75 +G + AA G L A + +A LFYTSGTTGRPKGVM TH N+++M M + DV Sbjct: 127 LGDAAWEQAAQGAPLPLQECAPEDVASLFYTSGTTGRPKGVMQTHRNLLAMTMAYFTDVD 186 Query: 76 PLASDDVLIHVAPMSHGSGLYSVPYFIRGGLQVIPESGGLDEAELFGLLNHYDKASLFAA 135 + DD +++ APMSHG+GLY+ + +RG V+PESGG D AEL L + SLFAA Sbjct: 187 DVRHDDAMVYAAPMSHGAGLYNYAHMLRGARHVVPESGGFDPAELVRLAAGVGRLSLFAA 246 Query: 136 PTIVMRLIQHVRNHTGVTWPGLRCLLVGGAPFYAEDIKSAVQCFGARVAQLYGQGETPMT 195 PT+V RL++HVR+ TG G + ++ GG P Y ED++ A+ G + Q+YGQGE+PMT Sbjct: 247 PTMVHRLVEHVRS-TGADAGGFKTIVYGGGPMYVEDLRRAIDAMGQKFVQIYGQGESPMT 305 Query: 196 ISALSADLLARAVAADDTAMLVSVGFAQTAIGITIVDADGNPVTAGTPGEVIVRGPTVMT 255 I+AL+ + LA + SVG A + + + +VD PV AG PGEV+VRG TVM Sbjct: 306 ITALAREHLADTAHPRWAERIASVGVAHSCVQVRVVDGQDRPVPAGEPGEVVVRGETVMA 365 Query: 256 GYWGNPEATRQTIGGGALRTGDIGLIDERGLLHLKDRSKDVIISGGTNIYPREVEEALLT 315 GYWGN EAT QT+ GG L TGD+G +DE G L L+DRSKDVIISGG+NIYPREVEE LL Sbjct: 366 GYWGNAEATAQTLRGGWLHTGDVGQLDEHGFLTLRDRSKDVIISGGSNIYPREVEEVLLQ 425 Query: 316 HPAVEEVSVVGAPDPEWGESVVAFIVCHAGASAGEQELDELCIRTIARFKRPKRYVFVEK 375 HP V E +VVG D EWGE VVAF+V GA + ELD LC+ IARFKRPK Y +V+ Sbjct: 426 HPRVREAAVVGRRDAEWGEVVVAFLVAD-GAPVPDAELDALCLAHIARFKRPKAYRWVQA 484 Query: 376 LPKNGTGKVLKRELQ 390 LPKN GKVLK EL+ Sbjct: 485 LPKNSYGKVLKTELR 499 >Q46MY5.1 Q46MY5_CUPPJ AMP-dependent synthetase and ligase Length = 537 Score = 389 bits (998), Expect = e-106, Method: Compositional matrix adjust. Identities = 199/384 (51%), Positives = 257/384 (66%), Gaps = 1/384 (0%) Query: 12 KIVDVGTDHYLDAASGPLLDAFPIAADALAWLFYTSGTTGRPKGVMLTHANMVSMAMHFL 71 K + V + Y +GP +A DALAWLFYTSGTTG+PKGVML+H N+ +M + Sbjct: 140 KTIAVDSTDYHALFAGPGAQVADVAEDALAWLFYTSGTTGKPKGVMLSHQNLAAMYWAYS 199 Query: 72 IDVQPLASDDVLIHVAPMSHGSGLYSVPYFIRGGLQVIPESGGLDEAELFGLLNHYDKAS 131 V + D LIH APMSHGSGLY VP+ G QVIP SGG + AEL L+ + + S Sbjct: 200 SAVSHIVPGDSLIHAAPMSHGSGLYIVPHIAEGASQVIPSSGGFNAAELVELVAVHPRTS 259 Query: 132 LFAAPTIVMRLIQHVRNHTGVTWPGLRCLLVGGAPFYAEDIKSAVQCFGARVAQLYGQGE 191 LFAAPT++ RL+++VR + L+ ++ GGAP Y ED +A+ C GA++AQ+YGQGE Sbjct: 260 LFAAPTMLNRLVEYVRR-SRADLSNLKVIVCGGAPLYLEDEVAALDCLGAKIAQIYGQGE 318 Query: 192 TPMTISALSADLLARAVAADDTAMLVSVGFAQTAIGITIVDADGNPVTAGTPGEVIVRGP 251 +PMTI+A ++ ++ A AA D L SVG A + I I D +P+ G GEV+VRG Sbjct: 319 SPMTITAQTSAEISGAHAASDFGGLASVGRALPGVEIRIADTHDDPLPVGEIGEVLVRGS 378 Query: 252 TVMTGYWGNPEATRQTIGGGALRTGDIGLIDERGLLHLKDRSKDVIISGGTNIYPREVEE 311 VM GYW NPEA+ T+ G L TGD+G +D+ G L LKDRSK+ IISGG+N+YPREVE+ Sbjct: 379 AVMQGYWNNPEASAVTLRNGWLHTGDVGCMDQSGRLTLKDRSKETIISGGSNVYPREVED 438 Query: 312 ALLTHPAVEEVSVVGAPDPEWGESVVAFIVCHAGASAGEQELDELCIRTIARFKRPKRYV 371 ALLTHPAV EVSV+G P+WGE VVA +V A + ELD+ C+R IARFKRPK Y+ Sbjct: 439 ALLTHPAVAEVSVLGRSHPDWGEEVVAIVVRKARSQVTISELDQWCLRRIARFKRPKAYL 498 Query: 372 FVEKLPKNGTGKVLKRELQQTLAN 395 FV+ LP+N GKVLK L+ LA Sbjct: 499 FVDSLPRNANGKVLKAALRDLLAK 522 >C1DGA5.1 C1DGA5_AZOVD AMP-dependent synthetase and ligase protein Length = 502 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 189/356 (53%), Positives = 249/356 (69%), Gaps = 1/356 (0%) Query: 38 DALAWLFYTSGTTGRPKGVMLTHANMVSMAMHFLIDVQPLASDDVLIHVAPMSHGSGLYS 97 D LAWLFYTSGTTGR KGVML+H N+++M++ + +DV P+ +DD ++ APMSHG+GLY+ Sbjct: 148 DDLAWLFYTSGTTGRAKGVMLSHGNLLAMSLCYPVDVDPVEADDAYVYAAPMSHGAGLYN 207 Query: 98 VPYFIRGGLQVIPESGGLDEAELFGLLNHYDKASLFAAPTIVMRLIQHVRNHTGVTWPGL 157 + G V+P S G D AELFGL + SLFAAPT++ R++ R G G+ Sbjct: 208 FIHVRCGARHVVPASRGFDAAELFGLAGTLGRLSLFAAPTMLKRMVGEARRR-GYAGDGI 266 Query: 158 RCLLVGGAPFYAEDIKSAVQCFGARVAQLYGQGETPMTISALSADLLARAVAADDTAMLV 217 + ++ GGAP Y D++ A+ FG R+ Q+YGQGE+PMTISAL +L+A AD + Sbjct: 267 KSIVCGGAPLYLADLREALATFGPRLIQIYGQGESPMTISALCRELIADRARADWPRLAA 326 Query: 218 SVGFAQTAIGITIVDADGNPVTAGTPGEVIVRGPTVMTGYWGNPEATRQTIGGGALRTGD 277 SVG+ Q+ + + ++DA G+P+ G PGEV+VRGP VM GYW + A+ T+ G LRTGD Sbjct: 327 SVGYPQSCVEVGVLDAAGDPLPPGRPGEVVVRGPCVMHGYWRDAAASAATLVDGWLRTGD 386 Query: 278 IGLIDERGLLHLKDRSKDVIISGGTNIYPREVEEALLTHPAVEEVSVVGAPDPEWGESVV 337 IG +D GLL L DRSKDVIISGG+NIYPREVEE L HPA+ EVSVVG PDPEWGESV Sbjct: 387 IGYLDRDGLLTLTDRSKDVIISGGSNIYPREVEEVLALHPAIAEVSVVGEPDPEWGESVA 446 Query: 338 AFIVCHAGASAGEQELDELCIRTIARFKRPKRYVFVEKLPKNGTGKVLKRELQQTL 393 AF+V G A Q L+ + +A FK+P+RY+FV +LPKNG GK+LK EL++ L Sbjct: 447 AFVVLRPGERADAQALNAWFVARLASFKKPRRYLFVRELPKNGYGKILKTELRRCL 502 >C5T0Q6.1 C5T0Q6_ACIDE AMP-dependent synthetase and ligase Length = 504 Score = 383 bits (983), Expect = e-104, Method: Compositional matrix adjust. Identities = 199/383 (51%), Positives = 252/383 (65%), Gaps = 1/383 (0%) Query: 9 PALKIVDVGTDHYLDAASGPLLDAFPIAADALAWLFYTSGTTGRPKGVMLTHANMVSMAM 68 P ++ G+D Y A + +D A +A LFYTSGTTGRPKGVM TH N+++M Sbjct: 120 PQDAVLVFGSDAYRTAVAHAPMDVCDRAPHDVASLFYTSGTTGRPKGVMQTHRNLLAMTA 179 Query: 69 HFLIDVQPLASDDVLIHVAPMSHGSGLYSVPYFIRGGLQVIPESGGLDEAELFGLLNHYD 128 + DV + D +++ APMSHG+GLY+ +RGG V+P SGG + AEL L Sbjct: 180 CYFTDVDDILPGDAMVYAAPMSHGAGLYNYAQVLRGGRHVVPLSGGFEPAELVQLAASVG 239 Query: 129 KASLFAAPTIVMRLIQHVRNHTGVTWPGLRCLLVGGAPFYAEDIKSAVQCFGARVAQLYG 188 + ++FAAPT+V RL+ HVR TG G + ++ GG P YA+D+++A+ G R Q+YG Sbjct: 240 QLTVFAAPTMVHRLVDHVRT-TGANVSGFKTIVYGGGPMYADDLRNALGVMGNRFVQIYG 298 Query: 189 QGETPMTISALSADLLARAVAADDTAMLVSVGFAQTAIGITIVDADGNPVTAGTPGEVIV 248 QGE+PMTI+ALS LA +VSVG AQ+ + + +VDA G PV AG GEV+V Sbjct: 299 QGESPMTITALSRAQLADRDHPRWAERMVSVGVAQSLVEVRVVDATGQPVPAGETGEVVV 358 Query: 249 RGPTVMTGYWGNPEATRQTIGGGALRTGDIGLIDERGLLHLKDRSKDVIISGGTNIYPRE 308 RG TVM GYW NP AT QT+ G L TGD+G +D G L LKDRSKDVIISGG+NIYPRE Sbjct: 359 RGDTVMPGYWNNPTATAQTLRDGWLYTGDMGALDSDGFLTLKDRSKDVIISGGSNIYPRE 418 Query: 309 VEEALLTHPAVEEVSVVGAPDPEWGESVVAFIVCHAGASAGEQELDELCIRTIARFKRPK 368 VEE LL HP V EV+VVG D EWGE V+AF+V G + ELD LC+ IARFKRPK Sbjct: 419 VEEVLLLHPRVREVAVVGQRDAEWGEVVIAFLVAGNGGAVAVAELDALCLEHIARFKRPK 478 Query: 369 RYVFVEKLPKNGTGKVLKRELQQ 391 Y +VE LPKN GKVLK EL++ Sbjct: 479 EYRWVEALPKNSYGKVLKTELRE 501