BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0221.p (448 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IT62.1 D8IT62_HERSS Signal transduction containing EAL and mod... 695 0.0 A6SXL7.1 A6SXL7_JANMA Signal transduction protein 503 e-140 A4G6Y4.1 A4G6Y4_HERAR Putative uncharacterized protein 491 e-137 Q2Y9D6.1 Q2Y9D6_NITMU Diguanylate phosphodiesterase (EAL domain) 445 e-123 Q47AV1.1 Q47AV1_DECAR EAL protein 313 3e-83 >D8IT62.1 D8IT62_HERSS Signal transduction containing EAL and modified HD-GYP domains protein Length = 448 Score = 695 bits (1794), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/412 (82%), Positives = 376/412 (91%) Query: 14 HHAHDFFLARQPILNREQELIGYELLFRNAAFGPANVNDDVSATASVIAHASELGLNNVI 73 H A DF+LARQPIL+REQ LIGYELLFR+AAFGPANV DDV+ATA+VIAHASELGL+NVI Sbjct: 13 HQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVI 72 Query: 74 GSLHGFINVDATVLMSDFINFLPADKVVLEILETVKVTPELVKRVNELVRAGYVFALDDV 133 G+L GFINVDA VLMSDFI FLP DKVVLEILETV+VTPELV RV ELV+AGYVFALDDV Sbjct: 73 GNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDV 132 Query: 134 ITESEDIAQLLPLVKIIKIDVMEVDASKLLKLSVHFKRAQKMLLAEKVETVEQFRDCVTF 193 + ES++I +LLPLVKIIKIDVMEVD SKLLKLSVHFKRAQK LLAEKVET++QF DCVTF Sbjct: 133 VAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTF 192 Query: 194 GFDYFQGYYFAKPVILQGKKLEASKIVIMHILTLLVRNVDNGEIVRYIKRDVALSLTLLR 253 GFDYFQGYYFAKP+ILQGKKLEASK+VIMH+LTLLVRNVDNGEIVR+IKRDVALSLTLLR Sbjct: 193 GFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLR 252 Query: 254 LVNTPVYGFMKHIDSLGQALIVLGRRQLKRWMQILLFANTEKDKAHTLSPLLILAATRGK 313 LVNTPVYGF K IDSLGQALIVLGRRQLKRW+QILLFANT+K++AHT+SPL+ILAATRGK Sbjct: 253 LVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGK 312 Query: 314 MLELITERIRPGRRKMSEIAFTVGIMSLVDALFGMPMETILTQITVSAEIRDALLFRTGF 373 MLELIT RIRPGRRKMSE+AFTVGIMSLVDALFGM MET+L QITVS EIR+ALL RTGF Sbjct: 313 MLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGF 372 Query: 374 YGEILQLAEATEKADKTPEQMKELLDGLQLSAEDFYELETQAFEWGNNISTN 425 YG L+L E TE+ D+ +M+ LLD LQLSA+DF+E E AFEWGN+IS N Sbjct: 373 YGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISNN 424 >A6SXL7.1 A6SXL7_JANMA Signal transduction protein Length = 425 Score = 503 bits (1294), Expect = e-140, Method: Compositional matrix adjust. Identities = 249/406 (61%), Positives = 311/406 (76%), Gaps = 1/406 (0%) Query: 18 DFFLARQPILNREQELIGYELLFRNAAFGPANVNDDVSATASVIAHASELGLNNVIGSLH 77 +FFLARQPILN +Q+L+ YELLFR A+ GPANV DD++ATASVIAHASELG+ NVIG+ Sbjct: 18 EFFLARQPILNNDQDLVAYELLFRRASSGPANVVDDLAATASVIAHASELGIGNVIGNSL 77 Query: 78 GFINVDATVLMSDFINFLPADKVVLEILETVKVTPELVKRVNELVRAGYVFALDDVITES 137 GF NVDA VLM DF+NFLP+DKVVLEILETV++T ELV+RV+ELV G+ FALDDVI+ S Sbjct: 78 GFFNVDAAVLMCDFVNFLPSDKVVLEILETVEITHELVERVSELVAQGFTFALDDVISHS 137 Query: 138 EDIAQLLPLVKIIKIDVMEVDASKLLKLSVHFKRAQKMLLAEKVETVEQFRDCVTFGFDY 197 + + LLPL+KIIKID+ + ++L KL+ HF+ K+LLAEKVET EQF C+ GF Y Sbjct: 138 DALKDLLPLIKIIKIDITGMSTTELGKLADHFRLEDKLLLAEKVETQEQFEACMKLGFHY 197 Query: 198 FQGYYFAKPVILQGKKLEASKIVIMHILTLLVRNVDNGEIVRYIKRDVALSLTLLRLVNT 257 FQGYYFA+PVIL GKKL S++ IM ++ L++ + D EI R IK+D +L LTLLRL NT Sbjct: 198 FQGYYFARPVILSGKKLAPSQLAIMQLMALIMADADTAEIERNIKKDASLVLTLLRLANT 257 Query: 258 PVYGFMKHIDSLGQALIVLGRRQLKRWMQILLFANTEKDKAHTLSPLLILAATRGKMLEL 317 P G + IDSLGQAL VLGRRQL+RW+QI+L+A K +H SPLL LA TRGK+LEL Sbjct: 258 PGVGVTQRIDSLGQALTVLGRRQLQRWLQIILYAEHNK-GSHFTSPLLQLATTRGKLLEL 316 Query: 318 ITERIRPGRRKMSEIAFTVGIMSLVDALFGMPMETILTQITVSAEIRDALLFRTGFYGEI 377 ITE++RP R M++ AFTVGIMSL+D LF ME IL Q++V E+ DALL+R GFYG++ Sbjct: 317 ITEKLRPDNRSMADTAFTVGIMSLMDTLFSQSMEEILDQVSVVEEVTDALLYRKGFYGDL 376 Query: 378 LQLAEATEKADKTPEQMKELLDGLQLSAEDFYELETQAFEWGNNIS 423 L+LAE E+ +KT + L LQLS ED Y L+ AFEW NN+S Sbjct: 377 LKLAEYIEQIEKTGALLIPTLQKLQLSIEDLYALQLAAFEWSNNVS 422 >A4G6Y4.1 A4G6Y4_HERAR Putative uncharacterized protein Length = 425 Score = 491 bits (1265), Expect = e-137, Method: Compositional matrix adjust. Identities = 247/418 (59%), Positives = 308/418 (73%), Gaps = 4/418 (0%) Query: 6 PDHDAAPAHHAHDFFLARQPILNREQELIGYELLFRNAAFGPANVNDDVSATASVIAHAS 65 PD A +FFLARQPILN EQ L+ YELLFR A GPANV DD++ATASVIAHAS Sbjct: 10 PDEQQA---RVKEFFLARQPILNSEQNLVAYELLFRRALSGPANVVDDLAATASVIAHAS 66 Query: 66 ELGLNNVIGSLHGFINVDATVLMSDFINFLPADKVVLEILETVKVTPELVKRVNELVRAG 125 ELG+ NVIG+ GF NVDA VLM DF+NFLP +KVVLEILETV+VTPELV RV EL G Sbjct: 67 ELGIVNVIGASLGFFNVDAAVLMRDFVNFLPCEKVVLEILETVEVTPELVARVAELSAQG 126 Query: 126 YVFALDDVITESEDIAQLLPLVKIIKIDVMEVDASKLLKLSVHFKRAQKMLLAEKVETVE 185 + FALDDVI+ +E + +LLPLVKIIKID+ + +++ KL +F+R K+LLAEKVET+E Sbjct: 127 FTFALDDVISHTEALQKLLPLVKIIKIDITGMTKAEIAKLVDYFRRDDKLLLAEKVETIE 186 Query: 186 QFRDCVTFGFDYFQGYYFAKPVILQGKKLEASKIVIMHILTLLVRNVDNGEIVRYIKRDV 245 QF+DC+ GF YFQGYYFA+PVIL GKKL S++ +M ++ L++ + D +I IK+D Sbjct: 187 QFQDCMDLGFHYFQGYYFARPVILSGKKLAPSQLAVMQLMALIMADADTADIEAIIKKDA 246 Query: 246 ALSLTLLRLVNTPVYGFMKHIDSLGQALIVLGRRQLKRWMQILLFANTEKDKAHTLSPLL 305 +L LTLLRL NTP G + IDSL QAL VLGRRQL+RW+QI+L+A K SPLL Sbjct: 247 SLVLTLLRLTNTPGLGVTRRIDSLSQALTVLGRRQLQRWLQIILYAEHHKGSQFN-SPLL 305 Query: 306 ILAATRGKMLELITERIRPGRRKMSEIAFTVGIMSLVDALFGMPMETILTQITVSAEIRD 365 LA TRGK+LELITE++RPG+R M++ AFTVGIMSL+D LFG M+ IL Q+ V ++ Sbjct: 306 QLATTRGKLLELITEKLRPGQRAMADTAFTVGIMSLMDTLFGQSMQQILEQVAVVDDVSS 365 Query: 366 ALLFRTGFYGEILQLAEATEKADKTPEQMKELLDGLQLSAEDFYELETQAFEWGNNIS 423 ALL R GFYG++L+LAE E+ +KT + L LQLS ED Y L+ AFEW N +S Sbjct: 366 ALLARRGFYGDLLKLAEYIEQIEKTGALLVPTLQKLQLSIEDLYALQLAAFEWSNIVS 423 >Q2Y9D6.1 Q2Y9D6_NITMU Diguanylate phosphodiesterase (EAL domain) Length = 424 Score = 445 bits (1144), Expect = e-123, Method: Compositional matrix adjust. Identities = 227/418 (54%), Positives = 297/418 (71%), Gaps = 5/418 (1%) Query: 9 DAAP----AHHAHDFFLARQPILNREQELIGYELLFRNAAFGPANVNDDVSATASVIAHA 64 D AP +FFLARQPIL++ Q LI YELLFR A +D AS+IAH Sbjct: 4 DTAPHISSVGQVKEFFLARQPILDQNQNLIAYELLFRRAGVRAPVSAEDTRGAASIIAHT 63 Query: 65 SELGLNNVIGSLHGFINVDATVLMSDFINFLPADKVVLEILETVKVTPELVKRVNELVRA 124 SELG+ NV GS GF NV++T+LM D +NFLPA+KVV E +T K+TPELV+RV EL +A Sbjct: 64 SELGIENVTGSALGFFNVNSTLLMGDLVNFLPAEKVVFEFPQTDKITPELVRRVAELAKA 123 Query: 125 GYVFALDDVITESEDIAQLLPLVKIIKIDVMEVDASKLLKLSVHFKRAQKMLLAEKVETV 184 GY FALDDVIT SE I LLP V+IIKID + + L L FK+A+K+LLA+KVET+ Sbjct: 124 GYRFALDDVITLSEYIKPLLPFVEIIKIDTSVMTYADLAMLVRQFKQARKVLLADKVETL 183 Query: 185 EQFRDCVTFGFDYFQGYYFAKPVILQGKKLEASKIVIMHILTLLVRNVDNGEIVRYIKRD 244 EQF++C GFDY+QGYYFAKP +L GKKL S++ IM ++TL+ R+ D EI + IK++ Sbjct: 184 EQFQNCHELGFDYYQGYYFAKPALLSGKKLATSQLAIMELMTLVARDADTIEIEQRIKKE 243 Query: 245 VALSLTLLRLVNTPVYGFMKHIDSLGQALIVLGRRQLKRWMQILLFANTEKDKAHTLSPL 304 V+L L+LLRLVNTP G K I SL +AL+VLGRRQL+RW+QI ++ + + SPL Sbjct: 244 VSLCLSLLRLVNTPAMGVTKSIHSLSEALMVLGRRQLQRWLQIQIYVGPDP-QIQFGSPL 302 Query: 305 LILAATRGKMLELITERIRPGRRKMSEIAFTVGIMSLVDALFGMPMETILTQITVSAEIR 364 L+LAATRGK+LEL+ ++++P R M++IAFTVGI+SL+DALFG ME IL QI +S EI Sbjct: 303 LLLAATRGKLLELVAQKLQPANRSMADIAFTVGILSLLDALFGQHMERILRQIVLSEEIT 362 Query: 365 DALLFRTGFYGEILQLAEATEKADKTPEQMKELLDGLQLSAEDFYELETQAFEWGNNI 422 +ALL+RTGFYG++L+LAE EK + + LL L L E+ Y + +AFEW N++ Sbjct: 363 EALLYRTGFYGDLLKLAEYLEKPGEAGRLLVPLLARLGLPIEELYPFQLEAFEWSNSL 420 >Q47AV1.1 Q47AV1_DECAR EAL protein Length = 417 Score = 313 bits (803), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 176/413 (42%), Positives = 256/413 (61%), Gaps = 12/413 (2%) Query: 16 AHDFFLARQPILNREQELIGYELLFRNAAFGPANVNDDVSATASVIAHA-SELGLNNVIG 74 A FL RQ IL+REQ L YELLFRN + A V D V ATA+VIA+A +ELG+ +G Sbjct: 6 ADQLFLGRQAILDREQRLHAYELLFRNGSRNFAEVTDGVQATATVIANAFTELGIEAALG 65 Query: 75 SLHGFINVDATVLMSDFINFLPADKVVLEILETVKVTPELVKRVNELVRAGYVFALDDVI 134 GFINVD L SD + LP VVLEILETV + +++R L AG+ ALDDVI Sbjct: 66 QHRGFINVDEQFLFSDMLELLPRHAVVLEILETVPPSDAVIERCKALKAAGFTLALDDVI 125 Query: 135 TESEDIAQLLPLVKIIKIDVMEVDASKLLKLSVHFKRAQKMLLAEKVETVEQFRDCVTFG 194 A+LL LV+I+K+D+ + +L++L + K K LLAEKV++ EQ C+ G Sbjct: 126 QLEPQFAELLALVEIVKVDIQPLSRVQLMQLVMKLKPMGKQLLAEKVDSREQMEQCLKLG 185 Query: 195 FDYFQGYYFAKPVILQGKKLEASKIVIMHILTLLVRNVDNGEIVRYIKRDVALSLTLLRL 254 F FQGYYFAKP I+ GKKL+ S++ +M ++ LL+ + D E+ +K + L++ LLR+ Sbjct: 186 FTLFQGYYFAKPTIIAGKKLDHSQLSLMKLMGLLLGDADTSELEAALKPEPGLTVNLLRM 245 Query: 255 VNTPVYGFMKHIDSLGQALIVLGRRQLKRWMQILLFANTEKDKAHTLSPLLILAATRGKM 314 N+ G + I SLG A+ VLGRRQL+RW+Q+L+FA+ ++ T +PLL +AATRG++ Sbjct: 246 TNSVGAGGTERITSLGHAITVLGRRQLQRWLQLLVFAS--GGQSPTENPLLQMAATRGRL 303 Query: 315 LELITERIRPGRRKMSEIAFTVGIMSLVDALFGMPMETILTQITVSAEIRDALLFRTGFY 374 +EL+ + PG +++ AF VGIMSL+ L G P+ I+ + ++ ++RDAL +G Sbjct: 304 MELLAGELSPGDNALADRAFMVGIMSLMPVLVGQPIADIVAPLGLATDVRDALCAGSGPL 363 Query: 375 GEILQLAEATEKADKTPEQMKELLDGLQ----LSAEDFYELETQAFEWGNNIS 423 G +L++AE++E + + EL L L + +TQA +W N I Sbjct: 364 GALLRIAESSENGN-----LAELATALTELPGLGPKAINRAQTQALQWANEIG 411