BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0076.p (439 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IZU4.1 D8IZU4_HERSS Transmembrane protease protein EC=3.4.-.- 660 0.0 A4G4K9.1 A4G4K9_HERAR Protein HflK 633 e-179 A6SZW3.1 A6SZW3_JANMA Membrane protease subunit HflK 572 e-161 C3X7J3.1 C3X7J3_OXAFO Membrane protease subunit HflK 504 e-141 C3X174.1 C3X174_OXAFO HflK protein 498 e-139 >D8IZU4.1 D8IZU4_HERSS Transmembrane protease protein EC=3.4.-.- Length = 450 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/450 (79%), Positives = 388/450 (86%), Gaps = 11/450 (2%) Query: 1 MLVSLFKKLGIKFSLNDPQWGRGSQDDNNRQNQNNGNNGKKPD------DGPPDLDQLWR 54 MLVSLF+K+G+KFSLNDPQWGRGSQ+DN N N K+P+ DGPPDLDQLWR Sbjct: 1 MLVSLFRKIGVKFSLNDPQWGRGSQNDNRDNQNNGNNGDKRPEKPSGNNDGPPDLDQLWR 60 Query: 55 DFNQRLSRLFGKRGGGGSDNGDGGGFNRGD-IKGAGIGAGVIAVIVAFLWLASGFFIVQE 113 DFNQRLS LFG++GGGGS +G GG +KGAGIG GVIAVIVAFLWLASGFFIVQE Sbjct: 61 DFNQRLSGLFGRKGGGGSSDGGNGGGFNRGDVKGAGIGVGVIAVIVAFLWLASGFFIVQE 120 Query: 114 GQTAVVMTFGKYSHTTLPGFNWRWPYPLQSHEIVNVSQVRTAEIGYRSNAKNKQLKEALM 173 GQTAVV TFG+YSHTTLPGFNWRWPYP+Q HEIVN+SQVRTAEIGYR N +NKQLKE+LM Sbjct: 121 GQTAVVTTFGRYSHTTLPGFNWRWPYPIQGHEIVNMSQVRTAEIGYRGNVRNKQLKESLM 180 Query: 174 LTDDENIIDIQFAVQYKLKNAAEWLFNNRDQDETVRQVAETAIREIVGRSKMDFVLYEGR 233 LTDDENIIDIQFAVQYKLKNAAEWLFNNRD D++VRQVAETAIREIVGRSKMDFVLYEGR Sbjct: 181 LTDDENIIDIQFAVQYKLKNAAEWLFNNRDPDDSVRQVAETAIREIVGRSKMDFVLYEGR 240 Query: 234 EKVALDVGQLMQQILDRYKSGVQITNVTMQGVQPPEQVQAAFDDAVKAGQDRERQKNEGQ 293 EKVALDV Q MQQILDRYKSGVQITNVTMQGVQPPEQVQAAFDDAVKAGQDRER KNEGQ Sbjct: 241 EKVALDVSQRMQQILDRYKSGVQITNVTMQGVQPPEQVQAAFDDAVKAGQDRERLKNEGQ 300 Query: 294 AYANDVIPKASGAASRLLEEAEAYRSRIVANAEGDAARFKQVLEEYQKAPAVTRDRMYLE 353 AYANDVIP+ASGAASRLLEEAEAYRSR+VANAEGDA+RF QV E Y KAPAVTRDRMY+E Sbjct: 301 AYANDVIPRASGAASRLLEEAEAYRSRVVANAEGDASRFTQVQEAYAKAPAVTRDRMYIE 360 Query: 354 TMQQIFSNTTKVMVDAKSGNNLLYLPLDKLIQQS----DNAAAAAKPATAPAGSSTASPT 409 TMQQIF+NTTKVMVDAKSG+NLLYLPLDKLIQQ+ A A A APA S+ + Sbjct: 361 TMQQIFANTTKVMVDAKSGSNLLYLPLDKLIQQTGPEAAAAGKPAASAAAPAASAANPAS 420 Query: 410 LPGTDPVYSTDVQRDSRNRDARDSRDREVR 439 G D VYS+++ RD RNRD R+SR+REVR Sbjct: 421 NAGNDTVYSSELMRDMRNRDPRESREREVR 450 >A4G4K9.1 A4G4K9_HERAR Protein HflK Length = 431 Score = 633 bits (1633), Expect = e-179, Method: Compositional matrix adjust. Identities = 323/443 (72%), Positives = 367/443 (82%), Gaps = 16/443 (3%) Query: 1 MLVSLFKKLGIKFSLNDPQWGRGSQDDNNRQNQNNGNNGKKPDDGPPDLDQLWRDFNQRL 60 MLVSL KK G+KFSLNDP+WGRGS D+ N+ +GK+P+DGPPDLDQLWRDFNQRL Sbjct: 1 MLVSLLKKFGLKFSLNDPRWGRGSDDNKNQ-------DGKRPNDGPPDLDQLWRDFNQRL 53 Query: 61 SRLFGKRGGGGSDNGDGGGFN----RGDIKGAGIGAGVIAVIVAFLWLASGFFIVQEGQT 116 LFG R GG + G+GG + D++GAGIGAGVIAVIVAFLWL SGFFIVQEGQT Sbjct: 54 GNLFGNRKNGGGNGGNGGNTGGTGFKPDMRGAGIGAGVIAVIVAFLWLVSGFFIVQEGQT 113 Query: 117 AVVMTFGKYSHTTLPGFNWRWPYPLQSHEIVNVSQVRTAEIGYRSNAKNKQLKEALMLTD 176 VV+TFGKYSH T GFNWRWP P+QSHE VNVSQVRT E+GYR + KNKQ +E+LMLT+ Sbjct: 114 GVVLTFGKYSHMTPAGFNWRWPAPIQSHETVNVSQVRTVEVGYRGSVKNKQHQESLMLTE 173 Query: 177 DENIIDIQFAVQYKLKNAAEWLFNNRDQDETVRQVAETAIREIVGRSKMDFVLYEGREKV 236 DENIIDIQFAVQY LKNA++W+FNNR+Q E V+QVAETAIRE+VGRSKMDFVLYEGREK+ Sbjct: 174 DENIIDIQFAVQYTLKNASDWVFNNREQGEMVKQVAETAIREVVGRSKMDFVLYEGREKI 233 Query: 237 ALDVGQLMQQILDRYKSGVQITNVTMQGVQPPEQVQAAFDDAVKAGQDRERQKNEGQAYA 296 A D QLMQQI+DRYK+GVQITNVTMQGVQPPEQVQA+FDDAVKAGQDRERQKNEGQAYA Sbjct: 234 AFDTSQLMQQIVDRYKAGVQITNVTMQGVQPPEQVQASFDDAVKAGQDRERQKNEGQAYA 293 Query: 297 NDVIPKASGAASRLLEEAEAYRSRIVANAEGDAARFKQVLEEYQKAPAVTRDRMYLETMQ 356 NDVIP+A GAASRL+EE+EAYRS + ANA+G+A+RFKQVL EYQKAPAVTRDRMYLETMQ Sbjct: 294 NDVIPRARGAASRLMEESEAYRSSVTANAQGEASRFKQVLVEYQKAPAVTRDRMYLETMQ 353 Query: 357 QIFSNTTKVMVDAKSGNNLLYLPLDKLIQQSDNAAAAAKPATAPAGSSTASPTLPGTDPV 416 +IFS+TTKVMVDAK GNNL+YLPLDKLI Q+ A AA +A SS LP Sbjct: 354 KIFSSTTKVMVDAKGGNNLIYLPLDKLIAQTAAPAGAAVAPSAATPSS-----LPSDSVA 408 Query: 417 YSTDVQRDSRNRDARDSRDREVR 439 T + +DSR RD+R SRDRE R Sbjct: 409 LETQLPQDSRTRDSRTSRDRESR 431 >A6SZW3.1 A6SZW3_JANMA Membrane protease subunit HflK Length = 424 Score = 572 bits (1473), Expect = e-161, Method: Compositional matrix adjust. Identities = 294/381 (77%), Positives = 333/381 (87%), Gaps = 11/381 (2%) Query: 11 IKFSLNDPQWGRGSQDDNNRQNQNNGNNGKKPDDGPPDLDQLWRDFNQRLSRLFGKRGGG 70 +KFSLNDP+WGRGS DDNN+ NQ+N K+P+DGPPDLDQLWRDFNQRLS +FG + G Sbjct: 1 MKFSLNDPRWGRGS-DDNNK-NQDN----KRPNDGPPDLDQLWRDFNQRLSNIFGNKKNG 54 Query: 71 GSDNGDGGGFN-----RGDIKGAGIGAGVIAVIVAFLWLASGFFIVQEGQTAVVMTFGKY 125 G NG + D++GAGIGA +IA IVAFLWL SGFFIVQEGQT VVMTFGKY Sbjct: 55 GGGNGGDSSGGGMGGFKPDMRGAGIGAAIIAGIVAFLWLVSGFFIVQEGQTGVVMTFGKY 114 Query: 126 SHTTLPGFNWRWPYPLQSHEIVNVSQVRTAEIGYRSNAKNKQLKEALMLTDDENIIDIQF 185 SH T GFNWRWP P+QSHEIVNVSQVRT E+GYR N KNKQ +E+LMLT+DENIIDIQF Sbjct: 115 SHMTPAGFNWRWPTPIQSHEIVNVSQVRTVEVGYRGNVKNKQQQESLMLTEDENIIDIQF 174 Query: 186 AVQYKLKNAAEWLFNNRDQDETVRQVAETAIREIVGRSKMDFVLYEGREKVALDVGQLMQ 245 AVQY LKNA++W+FNNR+Q+E V+QVAETAIRE+VGRSKMDFVLYEGREK+A D QLMQ Sbjct: 175 AVQYTLKNASDWVFNNREQEEMVKQVAETAIREVVGRSKMDFVLYEGREKIAFDSSQLMQ 234 Query: 246 QILDRYKSGVQITNVTMQGVQPPEQVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKASG 305 QI+DRYKSGVQITNVTMQGVQPPEQVQA+FDDAVKAGQDRERQKNEGQAYANDVIP+A G Sbjct: 235 QIVDRYKSGVQITNVTMQGVQPPEQVQASFDDAVKAGQDRERQKNEGQAYANDVIPRARG 294 Query: 306 AASRLLEEAEAYRSRIVANAEGDAARFKQVLEEYQKAPAVTRDRMYLETMQQIFSNTTKV 365 AASRLL+E+EAYRS + ANA+G+A+RFKQVL EYQKAPAVTRDRMYLETMQ+IFS+TTKV Sbjct: 295 AASRLLQESEAYRSSVTANAQGEASRFKQVLVEYQKAPAVTRDRMYLETMQKIFSSTTKV 354 Query: 366 MVDAKSGNNLLYLPLDKLIQQ 386 MVD+K N+L+YLPLDKLI Q Sbjct: 355 MVDSKGNNSLIYLPLDKLISQ 375 >C3X7J3.1 C3X7J3_OXAFO Membrane protease subunit HflK Length = 419 Score = 504 bits (1299), Expect = e-141, Method: Compositional matrix adjust. Identities = 239/367 (65%), Positives = 298/367 (81%), Gaps = 7/367 (1%) Query: 46 PPDLDQLWRDFNQRLSRLFGKRGGGGSDNGDGGGFNR-------GDIKGAGIGAGVIAVI 98 PPDLD++W+DFN R++RLF + G+D + KG + ++ I Sbjct: 31 PPDLDKMWKDFNNRINRLFRWKKKKGNDPQKPDDEDDDPYNDKVNGTKGLKMALCILFGI 90 Query: 99 VAFLWLASGFFIVQEGQTAVVMTFGKYSHTTLPGFNWRWPYPLQSHEIVNVSQVRTAEIG 158 A WLA+GFF+VQEGQT +VMTFG++SH PGFNWR P+P+QSHE+VNVSQVRT E+G Sbjct: 91 AAAFWLATGFFVVQEGQTGIVMTFGRFSHFAAPGFNWRKPWPIQSHEVVNVSQVRTVEVG 150 Query: 159 YRSNAKNKQLKEALMLTDDENIIDIQFAVQYKLKNAAEWLFNNRDQDETVRQVAETAIRE 218 YR+ KNK+L+EALMLT+DENI+DIQFAVQYKLKNA++W+FNNRDQ++ VRQVAETAIRE Sbjct: 151 YRTTLKNKRLEEALMLTNDENIVDIQFAVQYKLKNASDWVFNNRDQEDMVRQVAETAIRE 210 Query: 219 IVGRSKMDFVLYEGREKVALDVGQLMQQILDRYKSGVQITNVTMQGVQPPEQVQAAFDDA 278 +VG KMDFVLYEGR+++A + +LMQQI D+Y +GV +T+VTMQGVQPPE+VQAAFDDA Sbjct: 211 VVGGKKMDFVLYEGRDQIASEAQKLMQQIFDQYHAGVLVTSVTMQGVQPPEEVQAAFDDA 270 Query: 279 VKAGQDRERQKNEGQAYANDVIPKASGAASRLLEEAEAYRSRIVANAEGDAARFKQVLEE 338 VKAGQDRER KNEGQAYAN+V+P+A GAA+RL EEAE YR R++ANAEGD +RFKQ++ E Sbjct: 271 VKAGQDRERLKNEGQAYANEVVPRAKGAAARLKEEAEGYRQRVIANAEGDTSRFKQIVRE 330 Query: 339 YQKAPAVTRDRMYLETMQQIFSNTTKVMVDAKSGNNLLYLPLDKLIQQSDNAAAAAKPAT 398 YQKAPAVTRDRMYLETMQ+IFSNTTK+MVD+K GN LLYLPLDKLI QS NA+++ + Sbjct: 331 YQKAPAVTRDRMYLETMQEIFSNTTKLMVDSKKGNQLLYLPLDKLISQSGNASSSLGNSA 390 Query: 399 APAGSST 405 + A + T Sbjct: 391 SGASTET 397 >C3X174.1 C3X174_OXAFO HflK protein Length = 423 Score = 498 bits (1282), Expect = e-139, Method: Compositional matrix adjust. Identities = 238/352 (67%), Positives = 293/352 (83%), Gaps = 10/352 (2%) Query: 46 PPDLDQLWRDFNQRLSRLF-GKRGGG---------GSDNGDGGGFNRGDIKGAGIGAGVI 95 PPD++++W+DFN+RL+RLF KR D+ D G +G I G+I Sbjct: 33 PPDVEKMWKDFNRRLNRLFRWKRKKDQKPEDPEDPNKDDDDPFGDREARPRGLKIALGLI 92 Query: 96 AVIVAFLWLASGFFIVQEGQTAVVMTFGKYSHTTLPGFNWRWPYPLQSHEIVNVSQVRTA 155 +I WL +GF+ VQEGQT VVMTFG++S G NWR P+P+QSHE+VNVSQVRT Sbjct: 93 LLIATVFWLGTGFYSVQEGQTGVVMTFGRFSRFAPSGINWRIPWPIQSHEVVNVSQVRTV 152 Query: 156 EIGYRSNAKNKQLKEALMLTDDENIIDIQFAVQYKLKNAAEWLFNNRDQDETVRQVAETA 215 E+GYR+N +NK+L+EALMLT+DENI+DIQFAVQYKLK+AA+W+FNNRDQ++ VRQVAE+A Sbjct: 153 EVGYRNNLRNKKLEEALMLTNDENIVDIQFAVQYKLKDAADWVFNNRDQEDMVRQVAESA 212 Query: 216 IREIVGRSKMDFVLYEGREKVALDVGQLMQQILDRYKSGVQITNVTMQGVQPPEQVQAAF 275 IRE+VG KMDFVLYEGR+++A+D ++MQ+I D+Y+SGV +TNVTMQGVQPPEQVQAAF Sbjct: 213 IREVVGGKKMDFVLYEGRDQIAMDAQKIMQEIFDQYRSGVLVTNVTMQGVQPPEQVQAAF 272 Query: 276 DDAVKAGQDRERQKNEGQAYANDVIPKASGAASRLLEEAEAYRSRIVANAEGDAARFKQV 335 DDAVKAGQDRER KNEGQAYANDVIP+A GAA+RL EEAEAYR ++VANAEGDA+RF+Q+ Sbjct: 273 DDAVKAGQDRERLKNEGQAYANDVIPRARGAAARLKEEAEAYRHKVVANAEGDASRFRQI 332 Query: 336 LEEYQKAPAVTRDRMYLETMQQIFSNTTKVMVDAKSGNNLLYLPLDKLIQQS 387 + EYQKAPAVTRDRMYLETMQQIF+NTTK+MVDAK+GNNLLYLPLD+LI Q+ Sbjct: 333 VAEYQKAPAVTRDRMYLETMQQIFANTTKMMVDAKTGNNLLYLPLDRLIAQT 384