BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0068.p (422 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IZV1.1 D8IZV1_HERSS 4-hydroxy-3-methylbut-2-en-1-yl diphosphat... 796 0.0 A6SZX0.1 A6SZX0_JANMA 4-hydroxy-3-methylbut-2-en-1-yl diphosphat... 753 0.0 A4G4K2.1 A4G4K2_HERAR 4-hydroxy-3-methylbut-2-en-1-yl diphosphat... 750 0.0 F1W2W3.1 F1W2W3_9BURK 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosp... 728 0.0 B3R1K2.1 B3R1K2_CUPTR 4-hydroxy-3-methylbut-2-en-1-yl diphosphat... 715 0.0 >D8IZV1.1 D8IZV1_HERSS 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase EC=1.17.7.1 Length = 420 Score = 796 bits (2055), Expect = 0.0, Method: Compositional matrix adjust. Identities = 384/418 (91%), Positives = 403/418 (96%), Gaps = 2/418 (0%) Query: 1 MSSSPFPIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKD 60 MSSSP IASGPL RR SRR VI +G RE+ VGGGAPVMVQSMTNTDTADAIGTAIQIKD Sbjct: 1 MSSSP--IASGPLVRRNSRRVVISHGGREIVVGGGAPVMVQSMTNTDTADAIGTAIQIKD 58 Query: 61 LARAGSEVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKAL 120 LARAGSEVVR+TVN+PEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLL +YP+CA+AL Sbjct: 59 LARAGSEVVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTEYPECAQAL 118 Query: 121 SKYRINPGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAE 180 SKYRINPGNVGKGAKRD+QFAQMIE AC+YDKPVRIGVNWGSLDQALLARIMDENAGRAE Sbjct: 119 SKYRINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAE 178 Query: 181 PWPAQAVMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPL 240 PW AQAVMYEALVTSAIENAQRAEELG+AGDKIILSCKVSGVQDLIAVYRELARRCDYPL Sbjct: 179 PWSAQAVMYEALVTSAIENAQRAEELGMAGDKIILSCKVSGVQDLIAVYRELARRCDYPL 238 Query: 241 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMG 300 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRT+EV+VGQEILQTMG Sbjct: 239 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMG 298 Query: 301 LRKFTPMVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVN 360 LRKFTPMVIACPGCGRTTSTVFQDLADKIQT+LREQMP WKG YPGVE+MNVAVMGCIVN Sbjct: 299 LRKFTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVN 358 Query: 361 GPGESKHANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYGK 418 GPGESKHANIGISLPGTGESPAAPVFIDGEK+MTLRGE IAEEFQ +VLDYV++HYG+ Sbjct: 359 GPGESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGEHIAEEFQKVVLDYVESHYGQ 416 >A6SZX0.1 A6SZX0_JANMA 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase EC=1.17.7.1 Length = 423 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/417 (86%), Positives = 388/417 (93%) Query: 3 SSPFPIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKDLA 62 SS PIA+GP+ RRQSR AV+ YG REV +GG APV+VQSMTNTDTAD IGTAIQIK+LA Sbjct: 2 SSSNPIATGPVTRRQSRVAVVSYGGREVRIGGDAPVVVQSMTNTDTADIIGTAIQIKELA 61 Query: 63 RAGSEVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKALSK 122 RAGSE+VRITVN+PEAAAAVP I EQLD+M + VPLVGDFHYNGH LLNDYPDCAKAL+K Sbjct: 62 RAGSELVRITVNTPEAAAAVPEICEQLDKMDIVVPLVGDFHYNGHKLLNDYPDCAKALAK 121 Query: 123 YRINPGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAEPW 182 YRINPGNVGKG KRD+QFAQMIE ACR+DKPVRIGVNWGSLDQ LLARIMDENA R+ PW Sbjct: 122 YRINPGNVGKGNKRDTQFAQMIETACRFDKPVRIGVNWGSLDQELLARIMDENAARSTPW 181 Query: 183 PAQAVMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHL 242 AQAVMYEALVTSAIENA RAEE+GLAGD+IILSCKVSGVQDLIAVYRELARRCDYPLHL Sbjct: 182 SAQAVMYEALVTSAIENAMRAEEVGLAGDRIILSCKVSGVQDLIAVYRELARRCDYPLHL 241 Query: 243 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLR 302 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRT+EVIVGQEILQTMGLR Sbjct: 242 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVIVGQEILQTMGLR 301 Query: 303 KFTPMVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVNGP 362 KFTPMVIACPGCGRTTSTVFQ+LAD IQTYLR+QMP WK YPGVE+MNVAVMGCIVNGP Sbjct: 302 KFTPMVIACPGCGRTTSTVFQELADGIQTYLRDQMPVWKKEYPGVEAMNVAVMGCIVNGP 361 Query: 363 GESKHANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYGKQ 419 GESKHANIGISLPGTGESPAAPVF+DGEK +TLRG+ IAEEF IVLDYV++HYGK+ Sbjct: 362 GESKHANIGISLPGTGESPAAPVFVDGEKTVTLRGDNIAEEFHAIVLDYVKSHYGKE 418 >A4G4K2.1 A4G4K2_HERAR 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase EC=1.17.7.1 Length = 425 Score = 750 bits (1937), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/421 (86%), Positives = 389/421 (92%), Gaps = 1/421 (0%) Query: 1 MSSSPFPIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKD 60 MSSS PIA+GP RR+SR AV+ YG REV +GG APV+VQSMTNTDTAD IGTAIQIK+ Sbjct: 1 MSSSD-PIATGPFSRRKSRIAVVSYGGREVRIGGDAPVVVQSMTNTDTADVIGTAIQIKE 59 Query: 61 LARAGSEVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKAL 120 LARAGSE+VRITVN+PEAAAAVPAI EQLD+M V VPLVGDFHYNGHTLLNDYPDCAKAL Sbjct: 60 LARAGSEMVRITVNTPEAAAAVPAICEQLDKMDVVVPLVGDFHYNGHTLLNDYPDCAKAL 119 Query: 121 SKYRINPGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAE 180 +KYRINPGNVGKG KRD+QFAQMIE ACR+DKPVRIGVNWGSLDQ LLARIMDENA RA Sbjct: 120 AKYRINPGNVGKGNKRDTQFAQMIETACRFDKPVRIGVNWGSLDQELLARIMDENAARAH 179 Query: 181 PWPAQAVMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPL 240 PW AQAVMYEALVTSAIENA RAEE+GLAGD+IILSCKVSGVQDLIAVYRELARRCDYPL Sbjct: 180 PWTAQAVMYEALVTSAIENAMRAEEVGLAGDRIILSCKVSGVQDLIAVYRELARRCDYPL 239 Query: 241 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMG 300 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMG Sbjct: 240 HLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMG 299 Query: 301 LRKFTPMVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVN 360 LRKFTPMVIACPGCGRTTSTVFQ+LAD IQTYLR+QMP WK YPGVE+MNVAVMGCIVN Sbjct: 300 LRKFTPMVIACPGCGRTTSTVFQELADGIQTYLRDQMPVWKKQYPGVEAMNVAVMGCIVN 359 Query: 361 GPGESKHANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYGKQT 420 GPGESKHANIGISLPGTGESPAAPVF+DG K +TLRG+ IA EF IVLDYV++ YGK+ Sbjct: 360 GPGESKHANIGISLPGTGESPAAPVFVDGVKTVTLRGDNIAAEFHAIVLDYVKSRYGKEN 419 Query: 421 A 421 + Sbjct: 420 S 420 >F1W2W3.1 F1W2W3_9BURK 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Length = 429 Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/425 (85%), Positives = 390/425 (91%), Gaps = 3/425 (0%) Query: 1 MSSSPF---PIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQ 57 +SS P PI SGP RR R+ IR+G+ + VGG APV+VQSMTNTDTADAIGTAIQ Sbjct: 4 LSSDPLYCLPIPSGPALRRIVRQVAIRHGDHVILVGGDAPVVVQSMTNTDTADAIGTAIQ 63 Query: 58 IKDLARAGSEVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCA 117 IK+LARAGSE+VRITVN+ EAAAAVPAIREQLDRMGV+VPLVGDFHYNGHTLLNDYPDCA Sbjct: 64 IKELARAGSELVRITVNNAEAAAAVPAIREQLDRMGVNVPLVGDFHYNGHTLLNDYPDCA 123 Query: 118 KALSKYRINPGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAG 177 +ALSKYRINPGNVG+GAKRD+QFAQMIE AC+YDKPVRIGVNWGSLDQALLARIMDENA Sbjct: 124 RALSKYRINPGNVGQGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAK 183 Query: 178 RAEPWPAQAVMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCD 237 RA PW AQAVMYEAL+TSA++NA RAEELGLA DKIILSCKVSGVQDLIAVYRELA RCD Sbjct: 184 RAVPWTAQAVMYEALITSAVDNALRAEELGLARDKIILSCKVSGVQDLIAVYRELANRCD 243 Query: 238 YPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQ 297 YPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQ Sbjct: 244 YPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQ 303 Query: 298 TMGLRKFTPMVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGC 357 TMGLRKFTPMVIACPGCGRTTST FQ LAD IQTYLR+QMP WK YPGVE+MNVAVMGC Sbjct: 304 TMGLRKFTPMVIACPGCGRTTSTTFQSLADSIQTYLRDQMPVWKIDYPGVEAMNVAVMGC 363 Query: 358 IVNGPGESKHANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYG 417 IVNGPGES+HANIGISLPGTGE+PAAPVF+DGEK +TLRGE I+EEFQ IVLDYVQ+HYG Sbjct: 364 IVNGPGESRHANIGISLPGTGETPAAPVFVDGEKTVTLRGEHISEEFQAIVLDYVQSHYG 423 Query: 418 KQTAV 422 K T V Sbjct: 424 KTTPV 428 >B3R1K2.1 B3R1K2_CUPTR 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase EC=1.17.7.1 Length = 430 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/412 (83%), Positives = 375/412 (91%) Query: 6 FPIASGPLGRRQSRRAVIRYGEREVAVGGGAPVMVQSMTNTDTADAIGTAIQIKDLARAG 65 P+ GPL RRQ+R+A + +G+ V +GGGAPV VQSMTNTDT DAIGTAIQIK+LARAG Sbjct: 7 LPVLPGPLPRRQTRQARVAWGDNVVTIGGGAPVRVQSMTNTDTVDAIGTAIQIKELARAG 66 Query: 66 SEVVRITVNSPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLNDYPDCAKALSKYRI 125 SE+VRITVN+PEAAAAVP+IREQLDRMGVDVPLVGDFHYNGH LL DYP CA+ALSKYRI Sbjct: 67 SEIVRITVNTPEAAAAVPSIREQLDRMGVDVPLVGDFHYNGHKLLQDYPACAEALSKYRI 126 Query: 126 NPGNVGKGAKRDSQFAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWPAQ 185 NPGNVG+GAKRD+QFAQMIE ACRY+KPVRIGVNWGSLDQ LLARIMDENAGRAEPWPAQ Sbjct: 127 NPGNVGQGAKRDTQFAQMIEMACRYNKPVRIGVNWGSLDQDLLARIMDENAGRAEPWPAQ 186 Query: 186 AVMYEALVTSAIENAQRAEELGLAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLT 245 +VM EAL+TSAI++A++AEE+GL G +IILSCKVS VQ+LIAVYRELARRCDY LHLGLT Sbjct: 187 SVMIEALITSAIDSARKAEEIGLPGSQIILSCKVSQVQELIAVYRELARRCDYALHLGLT 246 Query: 246 EAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRKFT 305 EAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPG R +EV VGQEILQTMGLR FT Sbjct: 247 EAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGAPREKEVYVGQEILQTMGLRNFT 306 Query: 306 PMVIACPGCGRTTSTVFQDLADKIQTYLREQMPQWKGVYPGVESMNVAVMGCIVNGPGES 365 PMVIACPGCGRTTSTVFQ+LA IQ YLREQMPQWK YPGVE M+VAVMGCIVNGPGES Sbjct: 307 PMVIACPGCGRTTSTVFQELAASIQAYLREQMPQWKTAYPGVEEMDVAVMGCIVNGPGES 366 Query: 366 KHANIGISLPGTGESPAAPVFIDGEKRMTLRGERIAEEFQTIVLDYVQTHYG 417 KHANIGISLPG+GESPAAPVF+DG K TLRGERIAEEFQ IV +YV+THYG Sbjct: 367 KHANIGISLPGSGESPAAPVFVDGVKVKTLRGERIAEEFQAIVDEYVRTHYG 418