BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0039.p (521 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXP3.1 D8IXP3_HERSS Bifunctional: precorrin-3 methyltransferas... 821 0.0 E1MRH3.1 E1MRH3_9GAMM Precorrin-3B C17-methyltransferase 811 0.0 B5S4A6.1 B5S4A6_RALSO Bifunctional protein: precorrin-3 methyltr... 652 0.0 B5SC76.1 B5SC76_RALSO Bifunctional protein: precorrin-3 methyltr... 646 0.0 A3RT90.1 A3RT90_RALSO Precorrin-3B C17-methyltransferase / Preco... 646 0.0 >D8IXP3.1 D8IXP3_HERSS Bifunctional: precorrin-3 methyltransferase and precorrin-6x reductase oxidoreductase protein Length = 519 Score = 821 bits (2120), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/510 (78%), Positives = 444/510 (87%), Gaps = 5/510 (0%) Query: 3 GVLNLVSVGPGFGDLIVPRAIAALRDSNVIVAYELYLRWISSHIEGKEIHTPPLTQERER 62 GVLNLVSVGPGF ++I+PRAI ALR+S VIVAYELYLRWI++HIEGKEIHTPPLTQERER Sbjct: 8 GVLNLVSVGPGFEEMIIPRAIEALRESEVIVAYELYLRWIAAHIEGKEIHTPPLTQERER 67 Query: 63 ALLAIDKARSGEKVALISSGDIGIYAMAALAFDEMKEDDDYQVNVIPGVTSANACASLLG 122 ALLAI++AR+G +VALISSGDIGIYAMAALAFD+M+EDD Y+VNVIPGVTSANACASLLG Sbjct: 68 ALLAIEQARAGRRVALISSGDIGIYAMAALAFDDMREDDTYEVNVIPGVTSANACASLLG 127 Query: 123 SPLSHDFATLSLSNLLCPWEWIENRARHIAQADLACVLYNVQSAGRQEGVYRILKLMLES 182 SPLSHDFATLSLSNLLCPW WIE RA HIAQADLACVLYNVQSAGRQEGVYRIL+LML+ Sbjct: 128 SPLSHDFATLSLSNLLCPWTWIEQRASHIAQADLACVLYNVQSAGRQEGVYRILQLMLQH 187 Query: 183 KAPHTLCGVVKNAYRPGQEVSIHRLDELPSLQFDMLTSIVIGNRFTQRKRGYIFTPRGYN 242 KAPHTLCGVV+NAYRPGQ+V+IHRLDELP LQFDMLTSIVIGNRFTQRKR +IFTPRGYN Sbjct: 188 KAPHTLCGVVRNAYRPGQKVTIHRLDELPGLQFDMLTSIVIGNRFTQRKRDWIFTPRGYN 247 Query: 243 DWHDESVVAAEEPA-LPSQAVWVFAGTSDGNALAKQLAAQGHQVVVSTATEYGGELALQD 301 DW +ES AEE A LPSQAVWVFAGTSDGNALA +LA QG VVVSTAT YGGELA D Sbjct: 248 DWSEES--QAEEVAQLPSQAVWVFAGTSDGNALAAELAGQGRPVVVSTATGYGGELARGD 305 Query: 302 CPGVTVWAGRQGVEARKQALLRHEARVLVDATHPYATLMSQQLMGLSQSLGVPYLRYERP 361 CPG VW+GRQG+EAR+QAL ARVLVDATHP+A MSQQLM LSQ LG+PYLRYERP Sbjct: 306 CPGAFVWSGRQGLEARRQALRDSRARVLVDATHPFAVQMSQQLMTLSQELGIPYLRYERP 365 Query: 362 SAIADIANHALVCDSMEQAAEQAIARGERIFLATGSKDLATFLQAPGADRKQWFVRVTAE 421 +A HA C ME AA +A+A G+RIFLATGSKDLATFLQAPGA +QWF RVTA+ Sbjct: 366 GELAADDPHA--CADMEDAAHKAMAMGQRIFLATGSKDLATFLQAPGAQERQWFARVTAD 423 Query: 422 PEFIQRAIDLGIPRSRICAMQGPFSQGFNEALWRDWNIDCVVTKDSGDAGGYRAKADAAK 481 P+FI RA++LG+PR+ +CAMQGPFSQ FNEALWRDW IDCVVTKDSG+AGGY AKA+AA+ Sbjct: 424 PDFISRALELGLPRAHLCAMQGPFSQAFNEALWRDWGIDCVVTKDSGEAGGYHAKAEAAR 483 Query: 482 ALNIPLLTVRRPALDYPVQAGNLDEALAQV 511 AL IPLLTVRRP LDYP A + A + Sbjct: 484 ALGIPLLTVRRPPLDYPQVAHDFGSVRAHL 513 >E1MRH3.1 E1MRH3_9GAMM Precorrin-3B C17-methyltransferase Length = 533 Score = 811 bits (2095), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/531 (74%), Positives = 446/531 (83%), Gaps = 17/531 (3%) Query: 1 MSGVLNLVSVGPGFGDLIVPRAIAALRDSNVIVAYELYLRWISSHIEGKEIHTPPLTQER 60 M G+LNLVSVGPGF DLIVPRA AALRDS+VIVAY+LYLRWI I GKEIHTPPLTQER Sbjct: 1 MKGILNLVSVGPGFSDLIVPRAEAALRDSDVIVAYDLYLRWIEPWITGKEIHTPPLTQER 60 Query: 61 ERALLAIDKARSGEKVALISSGDIGIYAMAALAFDEMKEDDDYQVNVIPGVTSANACASL 120 ERALLAI+KARSG KVALISSGDIGIYAMAALAFDEM+EDDDY VNVIPG+TSANACASL Sbjct: 61 ERALLAIEKARSGAKVALISSGDIGIYAMAALAFDEMREDDDYAVNVIPGITSANACASL 120 Query: 121 LGSPLSHDFATLSLSNLLCPWEWIENRARHIAQADLACVLYNVQSAGRQEGVYRILKLML 180 LGSPLSHDFATLSLS+LLCPW+WIE R RHIAQADLACVLYNVQSAGRQEGVYRIL +ML Sbjct: 121 LGSPLSHDFATLSLSDLLCPWDWIEQRGRHIAQADLACVLYNVQSAGRQEGVYRILNIML 180 Query: 181 ESKAPHTLCGVVKNAYRPGQEVSIHRLDELPSLQFDMLTSIVIGNRFTQRKRGYIFTPRG 240 ESK+P TLCGV+ NAYRPGQ+VSIH L++L SLQFDMLT+IVIGNRFTQRKRG+IFTPRG Sbjct: 181 ESKSPKTLCGVIHNAYRPGQKVSIHHLEDLLSLQFDMLTTIVIGNRFTQRKRGFIFTPRG 240 Query: 241 YNDWH--DESVVAAEEPALPSQAVWVFAGTSDGNALAKQLAAQGHQVVVSTATEYGGELA 298 YN+W D + P LP QA+WVF+GTSDGNALA +LA QG+ VVVS ATEYGGE+A Sbjct: 241 YNNWDAPDVGEIPCGCPDLPEQALWVFSGTSDGNALANELAQQGYPVVVSAATEYGGEVA 300 Query: 299 LQDCPGVTVWAGRQGVEARKQALLRHEARVLVDATHPYATLMSQQLMGLSQSLGVPYLRY 358 Q CPGV+VWAG QGVEARKQAL +++ARV+VDATHPYA L+S+QLMGLS+SL +PYLRY Sbjct: 301 AQHCPGVSVWAGHQGVEARKQALSQNQARVIVDATHPYAKLISEQLMGLSKSLNIPYLRY 360 Query: 359 ERPSAIADIANH--ALVCD------------SMEQAAEQAIARGERIFLATGSKDLATFL 404 ERPS++ A H A + D S+EQAAEQAI G RIFL TGSKDLA FL Sbjct: 361 ERPSSVG-CAEHSEAHLSDSDALPSSAHPTCSLEQAAEQAIKLGRRIFLTTGSKDLAAFL 419 Query: 405 QAPGADRKQWFVRVTAEPEFIQRAIDLGIPRSRICAMQGPFSQGFNEALWRDWNIDCVVT 464 APGA ++WFVRVT EPEFIQRAIDLG+PRS ICAMQGPFS+ FN ALWRD IDCV+T Sbjct: 420 NAPGAAEREWFVRVTPEPEFIQRAIDLGVPRSHICAMQGPFSEAFNTALWRDLKIDCVIT 479 Query: 465 KDSGDAGGYRAKADAAKALNIPLLTVRRPALDYPVQAGNLDEALAQVERWQ 515 KDSGDAGGY+AK A +ALNIPLL ++RP L+YP + D AL+Q++ W Sbjct: 480 KDSGDAGGYQAKVAATQALNIPLLVIKRPKLEYPFTTSSFDAALSQLQAWH 530 >B5S4A6.1 B5S4A6_RALSO Bifunctional protein: precorrin-3 methyltransferase and precorrin-6x reductase EC=1.3.1.54 EC=2.1.1.131 Length = 523 Score = 652 bits (1683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/513 (65%), Positives = 391/513 (76%), Gaps = 9/513 (1%) Query: 1 MSGVLNLVSVGPGFGDLIVPRAIAALRDSNVIVAYELYLRWISSHIEGKEIHTPPLTQER 60 MSG L LVSVGPG +LI P AAL S+ IVAY+LYL WI+ I GK+I T PLTQER Sbjct: 1 MSGKLYLVSVGPGTRELIPPMVKAALEASDTIVAYDLYLTWIAPWIAGKDIRTLPLTQER 60 Query: 61 ERALLAIDKARSGEKVALISSGDIGIYAMAALAFDEMKEDDDYQVNVIPGVTSANACASL 120 RA LAI +AR+G VALISSGDIGIYAMAALAF+ M +DD + V VIPG+TSANACASL Sbjct: 61 ARAELAIGQARAGRTVALISSGDIGIYAMAALAFEAMADDDTFDVQVIPGITSANACASL 120 Query: 121 LGSPLSHDFATLSLSNLLCPWEWIENRARHIAQADLACVLYNVQSAGRQEGVYRILKLML 180 LGSPLSHDFATLSLS+LLCPW WIE RARHIAQADLA VLYNVQS RQEGVYRIL ++L Sbjct: 121 LGSPLSHDFATLSLSDLLCPWAWIETRARHIAQADLAVVLYNVQSRQRQEGVYRILDILL 180 Query: 181 ESKAPHTLCGVVKNAYRPGQEVSIHRLDELPSLQFDMLTSIVIGNRFTQRKRGYIFTPRG 240 E K TLCG+V NAYR GQ I L EL + +FDMLTS+VIGNRFT+RKRG+I+TPRG Sbjct: 181 EHKRAETLCGIVHNAYREGQATEIVTLAELRTRRFDMLTSLVIGNRFTRRKRGWIYTPRG 240 Query: 241 YNDWHD--ESVVAAEEPALPSQAVWVFAGTSDGNALAKQLAAQGHQVVVSTATEYGGELA 298 Y +W D ++V AA LP++AVWVF+GTSDGNALA+++AA G VVVS+A++YG LA Sbjct: 241 YGNWDDTPDTVTAA---GLPARAVWVFSGTSDGNALAREIAATGQGVVVSSASDYGAALA 297 Query: 299 LQDCPGVTVWAGRQGVEARKQALLRHEARVLVDATHPYATLMSQQLMGLSQSLGVPYLRY 358 Q CPGV+V AGR G+E R++ L AR +VDATHPYA MS+QL+ L+Q L +PYLRY Sbjct: 298 EQHCPGVSVVAGRLGIERRRELLRESGARAIVDATHPYAADMSRQLIRLAQELALPYLRY 357 Query: 359 ERPSAIADIANHALVCDSMEQAAEQAIARGERIFLATGSKDLATFLQAPGADRKQWFVRV 418 ERP SME AA A+ G+RIFLATGSKDLATF+ A GA R WFVRV Sbjct: 358 ERPGDAQAAPAQRAA--SMEDAACLAMQHGQRIFLATGSKDLATFVGADGASRHAWFVRV 415 Query: 419 TAEPEFIQRAIDLGIPRSRICAMQGPFSQGFNEALWRDWNIDCVVTKDSGDAGGYRAKAD 478 +P +QRAID GIPR+R+ AMQGPFSQ NEALWRDWNIDCVVTKDSGDAGGY+AK Sbjct: 416 APDPAHLQRAIDAGIPRARLVAMQGPFSQAANEALWRDWNIDCVVTKDSGDAGGYQAK-- 473 Query: 479 AAKALNIPLLTVRRPALDYPVQAGNLDEALAQV 511 AA AL IPL+ V RPA+DYP A + LAQ+ Sbjct: 474 AAAALGIPLIVVDRPAVDYPAVARDFAGVLAQL 506 >B5SC76.1 B5SC76_RALSO Bifunctional protein: precorrin-3 methyltransferase and precorrin-6x reductase EC=1.3.1.54 EC=2.1.1.131 Length = 525 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/514 (66%), Positives = 394/514 (76%), Gaps = 9/514 (1%) Query: 1 MSGVLNLVSVGPGFGDLIVPRAIAALRDSNVIVAYELYLRWISSHIEGKEIHTPPLTQER 60 MSG L LVSVGPG +LI P AAL S+ IVAY+LYL WI+ I GK+I T PLTQER Sbjct: 1 MSGKLYLVSVGPGTRELIPPMVKAALEASDTIVAYDLYLTWIAPWIAGKDIRTLPLTQER 60 Query: 61 ERALLAIDKARSGEKVALISSGDIGIYAMAALAFDEMKEDDDYQVNVIPGVTSANACASL 120 RA LAI +AR+G VALISSGDIGIYAMAALAF+ M +DD + V VIPG+TSANACASL Sbjct: 61 GRAELAIGQARAGRTVALISSGDIGIYAMAALAFEAMADDDTFDVQVIPGITSANACASL 120 Query: 121 LGSPLSHDFATLSLSNLLCPWEWIENRARHIAQADLACVLYNVQSAGRQEGVYRILKLML 180 LGSPLSHDFATLSLS+LLCPW WIE RARHIAQADLA VLYNVQS RQEGVYRIL ++L Sbjct: 121 LGSPLSHDFATLSLSDLLCPWAWIETRARHIAQADLAVVLYNVQSRQRQEGVYRILDILL 180 Query: 181 ESKAPHTLCGVVKNAYRPGQEVSIHRLDELPSLQFDMLTSIVIGNRFTQRKRGYIFTPRG 240 E K TLCG+V NAYR GQ I L EL + +FDMLTS+VIGNRFT+RKRG+I+TPRG Sbjct: 181 EHKRAETLCGIVHNAYREGQATEIVTLAELRTRRFDMLTSLVIGNRFTRRKRGWIYTPRG 240 Query: 241 YNDWHD--ESVVAAEEPALPSQAVWVFAGTSDGNALAKQLAAQGHQVVVSTATEYGGELA 298 Y +W D ++V AA LP+ AVWVF+GTSDGNALA+++AA G VVVS+A++YG LA Sbjct: 241 YGNWDDTPDTVTAA---GLPAHAVWVFSGTSDGNALAREIAATGQGVVVSSASDYGAALA 297 Query: 299 LQDCPGVTVWAGRQGVEARKQALLRHEARVLVDATHPYATLMSQQLMGLSQSLGVPYLRY 358 Q CPGV+V AGR G+E R++ L AR +VDATHPYA MS+QL+ L+Q L +PYLRY Sbjct: 298 EQHCPGVSVVAGRLGIERRRELLRESGARAIVDATHPYAADMSRQLIRLAQELALPYLRY 357 Query: 359 ERPS-AIADIANHALVCDSMEQAAEQAIARGERIFLATGSKDLATFLQAPGADRKQWFVR 417 ERP A A A SME AA A+ G+RIFLATGSKDLATF+ A GA R WFVR Sbjct: 358 ERPGDAQTAPAQRAA---SMEDAACLAMQHGQRIFLATGSKDLATFVGADGASRHAWFVR 414 Query: 418 VTAEPEFIQRAIDLGIPRSRICAMQGPFSQGFNEALWRDWNIDCVVTKDSGDAGGYRAKA 477 V +P +QRAID GIPR+R+ AMQGPFSQ NEALWRDWNIDCVVTKDSGDAGGY+AKA Sbjct: 415 VAPDPAHLQRAIDAGIPRARLVAMQGPFSQAANEALWRDWNIDCVVTKDSGDAGGYQAKA 474 Query: 478 DAAKALNIPLLTVRRPALDYPVQAGNLDEALAQV 511 AA AL IPL+ V RPA+DYP A + LAQ+ Sbjct: 475 AAAAALGIPLIVVDRPAVDYPAVARDFAGVLAQL 508 >A3RT90.1 A3RT90_RALSO Precorrin-3B C17-methyltransferase / Precorrin-6X reductase EC=1.3.1.54 EC=2.1.1.131 Length = 525 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/514 (66%), Positives = 394/514 (76%), Gaps = 9/514 (1%) Query: 1 MSGVLNLVSVGPGFGDLIVPRAIAALRDSNVIVAYELYLRWISSHIEGKEIHTPPLTQER 60 MSG L LVSVGPG +LI P AAL S+ IVAY+LYL WI+ I GK+I T PLTQER Sbjct: 1 MSGKLYLVSVGPGTRELIPPMVKAALEASDTIVAYDLYLTWIAPWIAGKDIRTLPLTQER 60 Query: 61 ERALLAIDKARSGEKVALISSGDIGIYAMAALAFDEMKEDDDYQVNVIPGVTSANACASL 120 RA LAI +AR+G VALISSGDIGIYAMAALAF+ M +DD + V VIPG+TSANACASL Sbjct: 61 GRAELAIGQARAGRTVALISSGDIGIYAMAALAFEAMADDDTFDVQVIPGITSANACASL 120 Query: 121 LGSPLSHDFATLSLSNLLCPWEWIENRARHIAQADLACVLYNVQSAGRQEGVYRILKLML 180 LGSPLSHDFATLSLS+LLCPW WIE RARHIAQADLA VLYNVQS RQEGVYRIL ++L Sbjct: 121 LGSPLSHDFATLSLSDLLCPWAWIETRARHIAQADLAVVLYNVQSRQRQEGVYRILDILL 180 Query: 181 ESKAPHTLCGVVKNAYRPGQEVSIHRLDELPSLQFDMLTSIVIGNRFTQRKRGYIFTPRG 240 E K TLCG+V NAYR GQ I L EL + +FDMLTS+VIGNRFT+RKRG+I+TPRG Sbjct: 181 EHKRAETLCGIVHNAYREGQATEIVTLAELRTRRFDMLTSLVIGNRFTRRKRGWIYTPRG 240 Query: 241 YNDWHD--ESVVAAEEPALPSQAVWVFAGTSDGNALAKQLAAQGHQVVVSTATEYGGELA 298 Y +W D ++V AA LP+ AVWVF+GTSDGNALA+++AA G VVVS+A++YG LA Sbjct: 241 YGNWDDTPDTVTAA---GLPAHAVWVFSGTSDGNALAREIAATGQGVVVSSASDYGAALA 297 Query: 299 LQDCPGVTVWAGRQGVEARKQALLRHEARVLVDATHPYATLMSQQLMGLSQSLGVPYLRY 358 Q CPGV+V AGR G+E R++ L AR +VDATHPYA MS+QL+ L+Q L +PYLRY Sbjct: 298 EQHCPGVSVVAGRLGIERRRELLRESGARAIVDATHPYAADMSRQLIRLAQELALPYLRY 357 Query: 359 ERPS-AIADIANHALVCDSMEQAAEQAIARGERIFLATGSKDLATFLQAPGADRKQWFVR 417 ERP A A A SME AA A+ G+RIFLATGSKDLATF+ A GA R WFVR Sbjct: 358 ERPGDAQTAPAQRAA---SMEDAACLAMQHGQRIFLATGSKDLATFVGADGASRHAWFVR 414 Query: 418 VTAEPEFIQRAIDLGIPRSRICAMQGPFSQGFNEALWRDWNIDCVVTKDSGDAGGYRAKA 477 V +P +QRAID GIPR+R+ AMQGPFSQ NEALWRDWNIDCVVTKDSGDAGGY+AKA Sbjct: 415 VAPDPAHLQRAIDAGIPRARLVAMQGPFSQAANEALWRDWNIDCVVTKDSGDAGGYQAKA 474 Query: 478 DAAKALNIPLLTVRRPALDYPVQAGNLDEALAQV 511 AA AL IPL+ V RPA+DYP A + LAQ+ Sbjct: 475 AAAAALGIPLIVVDRPAVDYPAVARDFAGVLAQL 508