BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0033.p (383 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value E1MRH8.1 E1MRH8_9GAMM Precorrin-8X methylmutase CbiC/CobH 514 e-144 B9Z3T0.1 B9Z3T0_9NEIS Precorrin-8X methylmutase CbiC/CobH 488 e-135 D8NH55.1 D8NH55_RALSO Putative precorrin-8X methylmutase (CobH/C... 481 e-133 Q8XS58.1 Q8XS58_RALSO Putative precorrin isomerase transmembrane... 477 e-132 D8MZR5.1 D8MZR5_RALSO Putative precorrin-8X methylmutase (CobH/C... 468 e-130 >E1MRH8.1 E1MRH8_9GAMM Precorrin-8X methylmutase CbiC/CobH Length = 525 Score = 514 bits (1324), Expect = e-144, Method: Compositional matrix adjust. Identities = 245/333 (73%), Positives = 283/333 (84%), Gaps = 1/333 (0%) Query: 20 YGIVIAGHGSRDADAVREFEALVEIVRARAPGRIVTHGYLEFSSPTISEAVDANLAAGSK 79 +GIVIAGHGSRDAD +REFE LVE+V+ RAP V+HGYLEF+SPTI +A+ A L A +K Sbjct: 9 FGIVIAGHGSRDADGIREFEQLVELVKERAPQHQVSHGYLEFASPTIDQAIAAQLNADAK 68 Query: 80 QVAVVPGVLLAARHAKNDMPAEVLELARRHPEVDFHFGAALNLHPQLLQLAQERILAAEA 139 Q+ +VPG+LLAA HAKND+P+E+L AR HP+VDFHFGA + LHP LLQ+ Q+RI+ AE+ Sbjct: 69 QIVMVPGILLAATHAKNDLPSELLTSAREHPDVDFHFGAPMGLHPLLLQVVQQRIVEAES 128 Query: 140 QSSQTIRRDDTCLVLVGRGTTDPDANGEVSKLARMLEEGMGFGGVYVCYSGTAKPLVADG 199 SS+T+RR DTCLVLVGRGTTDPDANG+V+K ARM+EEGMGFG YVCYSGTAKPLVADG Sbjct: 129 ASSKTVRRADTCLVLVGRGTTDPDANGDVAKFARMIEEGMGFGASYVCYSGTAKPLVADG 188 Query: 200 LRAAALLGFARIIVLPFFLFDGVLVKRIYAAADDLQQREPGLEVLKAGYLGVHQHVADVL 259 LRA A LG AR+IV+PFFLFDG+LVKRIY AAD +Q+REP LEVLKAGYLGVH +VADVL Sbjct: 189 LRAVAQLGCARLIVVPFFLFDGILVKRIYEAADAMQEREPELEVLKAGYLGVHPNVADVL 248 Query: 260 LERAREAVEGRAAMNCSLCKYRVQIVGFEEQIGEPQRAHHLQVRGLLSRETLVAEPQAEF 319 + RA+EAVEGRA MNCSLCKYRVQIVGFE+Q+GEPQR HHLQVRGL + V E EF Sbjct: 249 ISRAQEAVEGRAEMNCSLCKYRVQIVGFEQQVGEPQRPHHLQVRGLFEKAA-VDETVTEF 307 Query: 320 PPYVPHPIEKESFEIIAAGRDWSMFPPAHLTAL 352 PYVPHPIE ESF IIAAGRDWS+FP AHLT L Sbjct: 308 APYVPHPIEAESFRIIAAGRDWSVFPEAHLTVL 340 >B9Z3T0.1 B9Z3T0_9NEIS Precorrin-8X methylmutase CbiC/CobH Length = 525 Score = 488 bits (1255), Expect = e-135, Method: Compositional matrix adjust. Identities = 238/354 (67%), Positives = 273/354 (77%), Gaps = 5/354 (1%) Query: 19 SYGIVIAGHGSRDADAVREFEALVEIVRARAPGRIVTHGYLEFSSPTISEAVDANLAAGS 78 Y IV+AGHGSRD D + EF ALVE++RARA GR V HG+LEF++PTI EAV + AG+ Sbjct: 5 DYAIVLAGHGSRDPDGINEFMALVELLRARAGGRTVEHGFLEFATPTIDEAVGTVIEAGA 64 Query: 79 KQVAVVPGVLLAARHAKNDMPAEVLELARRHPEVDFHFGAALNLHPQLLQLAQERILAAE 138 K+V +VPGVLLAA HAKNDMP+E+L L R HP+ +FHFGAA++LHP+LLQL +ERI+ AE Sbjct: 65 KKVVMVPGVLLAATHAKNDMPSELLALQRAHPDTEFHFGAAMDLHPKLLQLCRERIVEAE 124 Query: 139 AQSSQTIRRDDTCLVLVGRGTTDPDANGEVSKLARMLEEGMGFGGVYVCYSGTAKPLVAD 198 +S QT+ R DTCLV+VGRGTTDPDAN E+SKL RMLEEG+GFG +VCYSGTAKPLVAD Sbjct: 125 GRSGQTVSRADTCLVVVGRGTTDPDANSEISKLTRMLEEGLGFGTSFVCYSGTAKPLVAD 184 Query: 199 GLRAAALLGFARIIVLPFFLFDGVLVKRIYAAADDLQQREPGLEVLKAGYLGVHQHVADV 258 GLRAAALLG+ RI+VLP+FLFDGVLVKRIYAAADDL R P LEVLKA YLGVH HVADV Sbjct: 185 GLRAAALLGYKRIVVLPYFLFDGVLVKRIYAAADDLATRHPELEVLKADYLGVHPHVADV 244 Query: 259 LLERAREAVEGRAAMNCSLCKYRVQIVGFEEQIGEPQRAHHLQVRGLLSRETLVAEPQAE 318 LERA+E VEGRA MNC+LCKYRVQIVGFEEQ+G PQ+ HH VRGLL R P Sbjct: 245 FLERAQEGVEGRATMNCALCKYRVQIVGFEEQVGTPQQGHHGLVRGLLGRTDTAPAPIDN 304 Query: 319 FPPYVPHPIEKESFEIIAAGRDWSMFPPAHLTALXAATSTRSTTS-----IFQP 367 +PPYVPHPIE ES II AG DWS P T L T S +F P Sbjct: 305 WPPYVPHPIEAESMRIIQAGYDWSTIPAELHTVLQRLVHTSGDFSSVDDMVFSP 358 >D8NH55.1 D8NH55_RALSO Putative precorrin-8X methylmutase (CobH/CbiC) Length = 534 Score = 481 bits (1237), Expect = e-133, Method: Compositional matrix adjust. Identities = 231/357 (64%), Positives = 277/357 (77%) Query: 18 ASYGIVIAGHGSRDADAVREFEALVEIVRARAPGRIVTHGYLEFSSPTISEAVDANLAAG 77 A Y IV+AGHGSRD D V EF ALV ++R RA GR V HG+LEF++PT+ EAVDA +A G Sbjct: 13 ADYAIVLAGHGSRDPDGVAEFLALVALLRERAGGRTVAHGFLEFATPTLDEAVDAVVAGG 72 Query: 78 SKQVAVVPGVLLAARHAKNDMPAEVLELARRHPEVDFHFGAALNLHPQLLQLAQERILAA 137 ++ V +VPGVLLAA HAKNDMP+E+L L + HP++DF FGAA++LHP+LL L +ERI+ A Sbjct: 73 ARTVVMVPGVLLAATHAKNDMPSELLALKQAHPQIDFRFGAAMDLHPKLLALCRERIVEA 132 Query: 138 EAQSSQTIRRDDTCLVLVGRGTTDPDANGEVSKLARMLEEGMGFGGVYVCYSGTAKPLVA 197 E +S+QT+ R DTCLV+VGRGT+DPDAN E++KL RMLEEGMGFG VCY+GTA+PLVA Sbjct: 133 EGRSAQTVSRADTCLVVVGRGTSDPDANSEIAKLTRMLEEGMGFGTSLVCYAGTARPLVA 192 Query: 198 DGLRAAALLGFARIIVLPFFLFDGVLVKRIYAAADDLQQREPGLEVLKAGYLGVHQHVAD 257 DGL+AAALLG+ RI+VLP+FLFDGVLVKRIY AADDL R P +EVL+A YLGVH HVAD Sbjct: 193 DGLKAAALLGYRRIVVLPYFLFDGVLVKRIYGAADDLAARHPEIEVLRAPYLGVHPHVAD 252 Query: 258 VLLERAREAVEGRAAMNCSLCKYRVQIVGFEEQIGEPQRAHHLQVRGLLSRETLVAEPQA 317 V LERARE +EGRAAMNC+LCKYRVQIVGFEEQ+G PQ++HH VRGLL R+ P A Sbjct: 253 VFLERAREGIEGRAAMNCALCKYRVQIVGFEEQVGTPQQSHHGLVRGLLGRDGATPAPAA 312 Query: 318 EFPPYVPHPIEKESFEIIAAGRDWSMFPPAHLTALXAATSTRSTTSIFQPVRLMPAS 374 ++PPYVPHPIE ES II AGRDWS P H L T I + P + Sbjct: 313 DWPPYVPHPIEAESMRIIDAGRDWSGVPADHQIVLKRLVHTSGDFDIVDDLYFSPGA 369 >Q8XS58.1 Q8XS58_RALSO Putative precorrin isomerase transmembrane protein Length = 534 Score = 477 bits (1228), Expect = e-132, Method: Compositional matrix adjust. Identities = 230/357 (64%), Positives = 276/357 (77%) Query: 18 ASYGIVIAGHGSRDADAVREFEALVEIVRARAPGRIVTHGYLEFSSPTISEAVDANLAAG 77 A Y IV+AGHGSRD D V EF ALV ++R RA GR V HG+LEF++PT+ EAVDA +A G Sbjct: 13 ADYAIVLAGHGSRDPDGVAEFLALVALLRERAGGRTVAHGFLEFATPTLDEAVDAVVADG 72 Query: 78 SKQVAVVPGVLLAARHAKNDMPAEVLELARRHPEVDFHFGAALNLHPQLLQLAQERILAA 137 + V +VPGVLLAA HAKNDMP+E+L L + HP+VDF FGAA++LHP+LL L +ERI+ A Sbjct: 73 AGTVVMVPGVLLAATHAKNDMPSELLALKQAHPQVDFRFGAAMDLHPKLLALCRERIVEA 132 Query: 138 EAQSSQTIRRDDTCLVLVGRGTTDPDANGEVSKLARMLEEGMGFGGVYVCYSGTAKPLVA 197 E +S+QT+ R DTCLV+VGRGT+DPDAN E++KL RMLEEGMGFG +VCY+GTA+PLVA Sbjct: 133 EGRSAQTVSRADTCLVVVGRGTSDPDANSEIAKLTRMLEEGMGFGTAFVCYAGTARPLVA 192 Query: 198 DGLRAAALLGFARIIVLPFFLFDGVLVKRIYAAADDLQQREPGLEVLKAGYLGVHQHVAD 257 DGL+AAA LG+ RI+VLP+FLFDGVLVKRIY AA+DL R P +EVL+A YLGVH HVAD Sbjct: 193 DGLKAAARLGYRRIVVLPYFLFDGVLVKRIYGAANDLAARHPEIEVLRAPYLGVHPHVAD 252 Query: 258 VLLERAREAVEGRAAMNCSLCKYRVQIVGFEEQIGEPQRAHHLQVRGLLSRETLVAEPQA 317 V LERARE +EGRAAMNC+LCKYRVQIVGFEEQ+G PQ++HH VRGLL R+ P A Sbjct: 253 VFLERAREGIEGRAAMNCALCKYRVQIVGFEEQVGTPQQSHHGLVRGLLGRDGATPAPAA 312 Query: 318 EFPPYVPHPIEKESFEIIAAGRDWSMFPPAHLTALXAATSTRSTTSIFQPVRLMPAS 374 ++PPYVPHPIE ES II AGRDWS P H L T I + P + Sbjct: 313 DWPPYVPHPIEAESMRIIDAGRDWSGVPADHQIVLKRLVHTSGDFDIVDDLYFSPGA 369 >D8MZR5.1 D8MZR5_RALSO Putative precorrin-8X methylmutase (CobH/CbiC) Length = 531 Score = 468 bits (1203), Expect = e-130, Method: Compositional matrix adjust. Identities = 234/357 (65%), Positives = 277/357 (77%) Query: 18 ASYGIVIAGHGSRDADAVREFEALVEIVRARAPGRIVTHGYLEFSSPTISEAVDANLAAG 77 A Y IV+AGHGSRD D V EF ALV ++R RA R V HG+LEF++PTI EAVDA +AAG Sbjct: 11 ADYAIVLAGHGSRDPDGVDEFMALVALLRERAGERTVAHGFLEFATPTIDEAVDAVVAAG 70 Query: 78 SKQVAVVPGVLLAARHAKNDMPAEVLELARRHPEVDFHFGAALNLHPQLLQLAQERILAA 137 +K V +VPGVLLAA HAKNDMP+E+L L + HPEVDF FGAA++LHP+LL L +ERI+ A Sbjct: 71 AKTVVMVPGVLLAATHAKNDMPSELLALKQAHPEVDFRFGAAMDLHPKLLALCRERIVEA 130 Query: 138 EAQSSQTIRRDDTCLVLVGRGTTDPDANGEVSKLARMLEEGMGFGGVYVCYSGTAKPLVA 197 E +S+QT+ R DTCLV+VGRGT+DPDAN E++KLARMLEEGMGFG +VCY+GTA+PLVA Sbjct: 131 EGRSAQTVSRADTCLVVVGRGTSDPDANSEIAKLARMLEEGMGFGTSFVCYAGTARPLVA 190 Query: 198 DGLRAAALLGFARIIVLPFFLFDGVLVKRIYAAADDLQQREPGLEVLKAGYLGVHQHVAD 257 DGL+AAALLG+ RI+VLP+FLFDGVLVKRIY+AADDL R P +E+L+A YLGVH HVAD Sbjct: 191 DGLKAAALLGYRRIVVLPYFLFDGVLVKRIYSAADDLAARHPEIEMLRAPYLGVHPHVAD 250 Query: 258 VLLERAREAVEGRAAMNCSLCKYRVQIVGFEEQIGEPQRAHHLQVRGLLSRETLVAEPQA 317 V LERARE +EGRAAMNC+LCKYRVQIVGFEEQ+G PQ+ HH VRGLL R P Sbjct: 251 VFLERAREGIEGRAAMNCALCKYRVQIVGFEEQVGTPQQGHHGLVRGLLGRNGTPPAPAT 310 Query: 318 EFPPYVPHPIEKESFEIIAAGRDWSMFPPAHLTALXAATSTRSTTSIFQPVRLMPAS 374 ++PPYVPHPIE ES II AGRDWS P H L T I + P + Sbjct: 311 DWPPYVPHPIEAESMRIIDAGRDWSGVPADHQIVLKRLVHTSGDFDIVDDLYFSPGA 367