BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0021.p (422 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value F1W061.1 F1W061_9BURK Na+/H+ antiporter-like protein 386 e-105 B1Z230.1 B1Z230_BURA4 Sodium/hydrogen exchanger 331 1e-88 B1K1M0.1 B1K1M0_BURCC Sodium/hydrogen exchanger 329 6e-88 B1FU01.1 B1FU01_9BURK Sodium/hydrogen exchanger 323 3e-86 E8YR69.1 E8YR69_9BURK Sodium/hydrogen exchanger 317 3e-84 >F1W061.1 F1W061_9BURK Na+/H+ antiporter-like protein Length = 414 Score = 386 bits (991), Expect = e-105, Method: Compositional matrix adjust. Identities = 228/426 (53%), Positives = 297/426 (69%), Gaps = 24/426 (5%) Query: 3 MVFLEPVLERLPFNAAMLYLPIGWLLGPSGVGLIRIDLESHADALTVITRVALLLSLFTV 62 M +E +L +LPF+ AMLYLP+G+ LGP G+GLI +D HA ALT++T +ALL+SLFTV Sbjct: 5 MALMESLLHKLPFSPAMLYLPVGYALGPGGIGLIDLDPVRHAGALTLVTEIALLISLFTV 64 Query: 63 GLKLRVAFRGEGSRLWWLPLRLGVVSMLITVPLLAICLAFLFGLQFAVAMLLAAILAPTD 122 GLKLR+ R WW+P+RLG ++ML+T+ LL FL GL A+LLAAI+APTD Sbjct: 65 GLKLRLPL---SDRRWWMPVRLGTLTMLVTIGLLTAVGVFLLGLSLGPAILLAAIIAPTD 121 Query: 123 PVLASDVQIQNVDDPDQLRFGLSGEGGLNDGSAYPFVLLALMLLGVTDDIAQVDHFG--W 180 PVLASDVQ+Q+ D D+LRF LSGEGG+NDG+ +PFV++ L L+GV A+ G Sbjct: 122 PVLASDVQVQDPRDHDRLRFSLSGEGGMNDGTTFPFVMIGLGLMGV-PMAARFTGAGAIG 180 Query: 181 FVAWGVIAGIGCGALAGWALSRTVLFARQRFGLALGMEEFMAIGVIMLSYGVAELIHGIG 240 V WG+ AG+ CG L G + R VL+ RQR LA+GMEEF+ +G+I LS+G+AELIHGIG Sbjct: 181 MVLWGIAAGLLCGWLVGRRVGRLVLYLRQRRQLAMGMEEFLTLGLIALSFGIAELIHGIG 240 Query: 241 FLAVFAAGLAMRQVESARSGDKPAGELIAAAQDSGKNAAVHPEQAPVYLTETVLGFNQQL 300 F+AVFA G+AMR++E SG + L A D+ +TETVLGFNQQL Sbjct: 241 FVAVFATGVAMRRIEHKASGVEADVTLSDQAIDAAN------------MTETVLGFNQQL 288 Query: 301 EHFAEFFMVLLIGILLSEYGLSREGVLIAALLFFIVRPIAVALGLLGSGTEISHRWLIAW 360 E AEF +VLL+GILLS YG+S EG+L+A LL ++RP+AV L LLG+ S R L++W Sbjct: 289 ERLAEFVVVLLLGILLSGYGVSYEGMLVAVLLLVVIRPVAVNLALLGATVTRSQRLLLSW 348 Query: 361 FGIRGVGSLYYLCFVLQFWHD-KLAARIAQD-----VLTVLALSILLHGISSTPLMHLYW 414 FGIRG+GSLYYL F LQ+ L +R+ + VLTVLA+SI++HG+SSTPLM Y Sbjct: 349 FGIRGIGSLYYLMFALQYVASVNLGSRMVSERFVPLVLTVLAVSIVVHGMSSTPLMQWYR 408 Query: 415 RKRVAA 420 R+R A Sbjct: 409 RRRRPA 414 >B1Z230.1 B1Z230_BURA4 Sodium/hydrogen exchanger Length = 429 Score = 331 bits (848), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 193/421 (45%), Positives = 261/421 (61%), Gaps = 15/421 (3%) Query: 1 MFMVFLEPVLERLPFNAAMLYLPIGWLLGPSGVGLIRIDLESHADALTVITRVALLLSLF 60 +FM + L+RLP +AAM+YL IG+L+GPSG+G + + L L + + LL+SLF Sbjct: 15 IFMGLVGSSLKRLPLSAAMVYLGIGFLVGPSGIGFLAMTLPDDVTRLRIAAEIGLLISLF 74 Query: 61 TVGLKLRVAFRGEGSRLWWLPLRLGVVSMLITVPLLAICLAFLFGLQFAVAMLLAAILAP 120 +GL+LRV R W LPLRLGVV+M+ TV +A + L VA+LL A++AP Sbjct: 75 AIGLRLRVP---PADRRWMLPLRLGVVAMIFTVASIAALGMLVLHLSLGVAVLLGAMIAP 131 Query: 121 TDPVLASDVQIQNVDDPDQLRFGLSGEGGLNDGSAYPFVLLALMLLGVTDDIAQVDHFGW 180 TDPVLA DV +++ D + +RF LSGEGG+NDG+AYP +L L+L D + W Sbjct: 132 TDPVLAHDVGVRDAGDVELVRFSLSGEGGINDGTAYPCAVLGLLLC----DSSATSALHW 187 Query: 181 F----VAWGVIAGIGCGALAGWALSRTVLFARQRFGLALGMEEFMAIGVIMLSYGVAELI 236 VAWG+ +G+G G L G A +R V F R R G ALG+E F A+G+IMLSYG A + Sbjct: 188 NMVGGVAWGIASGVGVGWLLGLATARLVAFLRSRHGQALGLEGFFALGLIMLSYGAALAV 247 Query: 237 HGIGFLAVFAAGLAMRQVESARSGDKPAGELIAAAQDSGKNA-AVHPEQAPVYLTETVLG 295 HG GFLAVFAAG+AMR+VE SG K + E + A + +P++A ++ E+V+G Sbjct: 248 HGYGFLAVFAAGVAMRRVEHRTSGRKTSKETVGVVDSEDVEATSTNPDKAHAFVAESVMG 307 Query: 296 FNQQLEHFAEFFMVLLIGILLSEY---GLSREGVLIAALLFFIVRPIAVALGLLGSGTEI 352 F +LEH AE ++LLIG L+S Y L+ G + A L ++RP A L L+GS Sbjct: 308 FTIELEHIAEAVLILLIGALVSRYWADMLTWTGAAVVASLLLVIRPTATWLALIGSRASR 367 Query: 353 SHRWLIAWFGIRGVGSLYYLCFVLQFWHDKLAARIAQDVLTVLALSILLHGISSTPLMHL 412 R LI WFGIRGVGSLYYL L+ + VL ++A+SI+LHGIS+TPLM Sbjct: 368 HQRRLIGWFGIRGVGSLYYLMLSLEQGPRAELLPLVPQVLAIIAVSIVLHGISATPLMRR 427 Query: 413 Y 413 Y Sbjct: 428 Y 428 >B1K1M0.1 B1K1M0_BURCC Sodium/hydrogen exchanger Length = 429 Score = 329 bits (843), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 191/421 (45%), Positives = 261/421 (61%), Gaps = 15/421 (3%) Query: 1 MFMVFLEPVLERLPFNAAMLYLPIGWLLGPSGVGLIRIDLESHADALTVITRVALLLSLF 60 +FM + L+RLP +AAM+YL IG+L+GP+G+G + + L L + + LL+SLF Sbjct: 15 IFMGLIGSSLKRLPLSAAMVYLGIGFLIGPAGLGFLSLTLPDDVTHLRIAAEIGLLISLF 74 Query: 61 TVGLKLRVAFRGEGSRLWWLPLRLGVVSMLITVPLLAICLAFLFGLQFAVAMLLAAILAP 120 +GL+LRV R W LPLRLGVV+M+ TV +A + L VA+LL A++AP Sbjct: 75 AIGLRLRVP---PADRRWMLPLRLGVVAMIFTVASIAALGMLVLHLSLGVAVLLGAMIAP 131 Query: 121 TDPVLASDVQIQNVDDPDQLRFGLSGEGGLNDGSAYPFVLLALMLLGVTDDIAQVDHFGW 180 TDPVLA DV +++ D + +RF LSGEGG+NDG+AYP ++ L+ G + W Sbjct: 132 TDPVLAHDVGVRDAGDVELVRFSLSGEGGINDGTAYPCAVIGLLACGS----GTMSELHW 187 Query: 181 F----VAWGVIAGIGCGALAGWALSRTVLFARQRFGLALGMEEFMAIGVIMLSYGVAELI 236 +AWG+ +G+G G L G+A +R V F R R G ALG+E F A+G+IMLSYGV I Sbjct: 188 SMLGGIAWGITSGVGAGWLLGFATARLVAFLRSRHGQALGLEGFFALGLIMLSYGVTLAI 247 Query: 237 HGIGFLAVFAAGLAMRQVESARSGDKPAGELIAAAQDSGKNA-AVHPEQAPVYLTETVLG 295 HG GFLAVFAAG+AMR+VE SG K + E + A A P++A ++ E+V+G Sbjct: 248 HGYGFLAVFAAGVAMRRVEHRTSGRKTSKETVGIVDSEDVEATATDPDKAHAFVAESVMG 307 Query: 296 FNQQLEHFAEFFMVLLIGILLSEY---GLSREGVLIAALLFFIVRPIAVALGLLGSGTEI 352 F +LEH AE ++LLIG L+S Y L+ G + A L F++RP A L L+GS Sbjct: 308 FTIELEHIAEAVLILLIGALVSRYWVDMLTWAGAAVVATLLFVIRPAATGLALIGSQASR 367 Query: 353 SHRWLIAWFGIRGVGSLYYLCFVLQFWHDKLAARIAQDVLTVLALSILLHGISSTPLMHL 412 R LI+WFGIRGVGSLYYL L+ + VL ++A+SI+LHGIS+ PLM Sbjct: 368 HQRRLISWFGIRGVGSLYYLMLALEQGPRAQLLPLVPWVLAIIAMSIVLHGISAAPLMRR 427 Query: 413 Y 413 Y Sbjct: 428 Y 428 >B1FU01.1 B1FU01_9BURK Sodium/hydrogen exchanger Length = 439 Score = 323 bits (829), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 190/425 (44%), Positives = 262/425 (61%), Gaps = 12/425 (2%) Query: 1 MFMVFLEPVLERLPFNAAMLYLPIGWLLGPSGVGLIRIDLESHADALTVITRVALLLSLF 60 +FM L RLP +AAM+Y+ IG+ LGP GVGL+ +D+ + A L ++T VALL+SLF Sbjct: 15 VFMGVAATTLRRLPVSAAMVYVAIGYALGPPGVGLLHLDMAADAHLLRMLTEVALLVSLF 74 Query: 61 TVGLKLRVAFRGEGSRLWWLPLRLGVVSMLITVPLLAICLAFLFGLQFAVAMLLAAILAP 120 +GL+LRV G +LW +PLRLG ++ML TVPLLA+ ++ L + A+LLAAILAP Sbjct: 75 AIGLRLRV---GVLDKLWMVPLRLGFLAMLATVPLLALFCVYVLHLGWGPAILLAAILAP 131 Query: 121 TDPVLASDVQIQNVDDPDQLRFGLSGEGGLNDGSAYPFVLLALMLLGV----TDDIAQVD 176 TDPVLA DVQ+ N D D LRF LSGEGGLNDG A PF ++ L + D+ + Sbjct: 132 TDPVLAHDVQVHNPGDHDLLRFALSGEGGLNDGIALPFAMIGLAFCAMHGAGAGDVLNLK 191 Query: 177 HFGWFVAWGVIAGIGCGALAGWALSRTVLFARQRFGLALGMEEFMAIGVIMLSYGVAELI 236 WGV+ I GAL GW + V + R RF ALG+E F A+G+I LS+G A+L Sbjct: 192 -LAASAVWGVLGAIAIGALLGWVTTHAVAWLRTRFAHALGLEGFFALGLIGLSFGAAQLA 250 Query: 237 HGIGFLAVFAAGLAMRQVESARSGDKPAGELIAAAQDSGKNA-AVHPEQAPVYLTETVLG 295 H GFLAVFAAG++MR+VE SG E I + A A P++A ++TE+VLG Sbjct: 251 HTYGFLAVFAAGVSMRRVEYRASGGTSPRETIGTVDSADVEATASDPDKAHAFMTESVLG 310 Query: 296 FNQQLEHFAEFFMVLLIGILLSEYG---LSREGVLIAALLFFIVRPIAVALGLLGSGTEI 352 F +LE AE ++ ++G +L+ + + + + LF VRP +VAL L+GS Sbjct: 311 FTIELERIAEVIIMAMVGNVLATLAAPLFTWQALALVIALFMFVRPASVALSLIGSAASP 370 Query: 353 SHRWLIAWFGIRGVGSLYYLCFVLQFWHDKLAARIAQDVLTVLALSILLHGISSTPLMHL 412 + R L++WFGIRGVGS YYL + L+ + L V+ S+++HG+S+TPLM+ Sbjct: 371 TQRRLMSWFGIRGVGSFYYLAYSLEHGPAADIKPLVPLALAVVTASVVIHGVSATPLMNR 430 Query: 413 YWRKR 417 Y R R Sbjct: 431 YRRLR 435 >E8YR69.1 E8YR69_9BURK Sodium/hydrogen exchanger Length = 439 Score = 317 bits (811), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 187/419 (44%), Positives = 257/419 (61%), Gaps = 12/419 (2%) Query: 1 MFMVFLEPVLERLPFNAAMLYLPIGWLLGPSGVGLIRIDLESHADALTVITRVALLLSLF 60 +FM L RLP +AAM+YL IG+ LGP G+GL+ +D+ + A L +T +ALL+SLF Sbjct: 15 VFMGLAATTLRRLPVSAAMVYLAIGYALGPPGLGLLHLDMSADAHLLRTLTEIALLVSLF 74 Query: 61 TVGLKLRVAFRGEGSRLWWLPLRLGVVSMLITVPLLAICLAFLFGLQFAVAMLLAAILAP 120 +GL+LRV G +LW +PLRLG ++ML TVPLLA+ ++ L + A+LLAAILAP Sbjct: 75 AIGLRLRV---GVLDKLWTVPLRLGFLAMLATVPLLALFCVYVLHLGWGPAILLAAILAP 131 Query: 121 TDPVLASDVQIQNVDDPDQLRFGLSGEGGLNDGSAYPFVLLALMLLGV----TDDIAQVD 176 TDPVLA DVQ+ N D D LRF LSGEGGLNDG A PF ++ L + D+ + Sbjct: 132 TDPVLAHDVQVHNPGDHDLLRFALSGEGGLNDGIALPFAMVGLAFCAMHGASAGDVLNLK 191 Query: 177 HFGWFVAWGVIAGIGCGALAGWALSRTVLFARQRFGLALGMEEFMAIGVIMLSYGVAELI 236 G AWGV+ I G L GWA + V + R R+ ALG+E F A+G+I LS+G A+L Sbjct: 192 LAG-AAAWGVLGAIAIGGLLGWATTHAVAWLRMRYAHALGLEGFFALGLIGLSFGAAQLA 250 Query: 237 HGIGFLAVFAAGLAMRQVESARSGDKPAGELIAAAQDSGKNA-AVHPEQAPVYLTETVLG 295 GFLAVFAAG++MR+VE SG E I + A A P++A ++TE+VLG Sbjct: 251 QTYGFLAVFAAGVSMRRVEHRASGGSSPREAIGTVDSADVEATASDPDKAHAFMTESVLG 310 Query: 296 FNQQLEHFAEFFMVLLIGILLSEYG---LSREGVLIAALLFFIVRPIAVALGLLGSGTEI 352 F +LE AE ++ ++G +L+ + + LFF VRP +V L LLGS Sbjct: 311 FTIELERIAEVIIMAMVGNVLATLSAPLFTWHAFALIVALFFFVRPASVELSLLGSAASP 370 Query: 353 SHRWLIAWFGIRGVGSLYYLCFVLQFWHDKLAARIAQDVLTVLALSILLHGISSTPLMH 411 + R L++WFGIRGVGS YYL + L+ + L V+ S+++HG+S+TPLM+ Sbjct: 371 TQRRLMSWFGIRGVGSFYYLAYALEHGPAADIQPLMPLALAVVTASVVIHGVSATPLMN 429