BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0155.p (480 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1W7.1 D8J1W7_HERSS Multidrug resistance protein protein 818 0.0 E1TFN9.1 E1TFN9_BURSG Drug resistance transporter, EmrB/QacA sub... 717 0.0 Q7P060.1 Q7P060_CHRVO Probable multidrug resistance protein 677 0.0 F0LRP4.1 F0LRP4_VIBFU Multidrug resistance protein VceB 673 0.0 B9YZQ5.1 B9YZQ5_9NEIS Drug resistance transporter, EmrB/QacA sub... 671 0.0 >D8J1W7.1 D8J1W7_HERSS Multidrug resistance protein protein Length = 525 Score = 818 bits (2114), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/480 (82%), Positives = 440/480 (91%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLDTTIANVSVSTI+GALGAS+SQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFI SM Sbjct: 46 VLDTTIANVSVSTIAGALGASTSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFILSM 105 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 ++FG+FSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKA AAVGLWAMT Sbjct: 106 VMFGLFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAPAAVGLWAMT 165 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+APIAGPILGGVLCDQYSWPYIF+INVPVALICGY+GW+MLKRYE+ + KLPID+VGL Sbjct: 166 TLVAPIAGPILGGVLCDQYSWPYIFWINVPVALICGYIGWRMLKRYETKMSKLPIDRVGL 225 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 +LMV+WVAALQLMLDEGKEKDWFASTEIV+LA+ A FIAFLIWELTERNPIVDLRVFR Sbjct: 226 VLMVVWVAALQLMLDEGKEKDWFASTEIVLLAVTAVVFFIAFLIWELTERNPIVDLRVFR 285 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRG+TASVTTICLAFGAFFG+ VLTPLWLQGYMGYTAT SG +ALTGILAV+TAP VAK Sbjct: 286 HRGFTASVTTICLAFGAFFGSVVLTPLWLQGYMGYTATWSGCISALTGILAVMTAPMVAK 345 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 +ST +D RKLV IGV WLG +T R+FNTTDMS FQIGWPL + GIGLPLFFVPLTGLAL Sbjct: 346 MSTTIDARKLVCIGVTWLGFITFLRAFNTTDMSFFQIGWPLFLQGIGLPLFFVPLTGLAL 405 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 SSV E ETASAAGLMSFCRTM+GAIATS+VNTSWEN + Y+HAEL+G+VD+ GD +T+ Sbjct: 406 SSVNEEETASAAGLMSFCRTMAGAIATSIVNTSWENDATYFHAELSGLVDRGGDAIHTMM 465 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKRVADTSAAH 480 +GMS +QA A++ Q +Q+Q++MLSTNHIFMMAA+SF LAA AVW APKP RVADTSAAH Sbjct: 466 ASGMSAEQATASLAQTVQNQAVMLSTNHIFMMAAVSFSLAALAVWLAPKPTRVADTSAAH 525 >E1TFN9.1 E1TFN9_BURSG Drug resistance transporter, EmrB/QacA subfamily Length = 513 Score = 717 bits (1852), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/480 (72%), Positives = 407/480 (84%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLDTTIANVSV TI+GA+GASSSQGTYVITSYAVAEAITVPLTGWLA RFGTVRVFI S+ Sbjct: 34 VLDTTIANVSVPTIAGAMGASSSQGTYVITSYAVAEAITVPLTGWLAGRFGTVRVFIASL 93 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 I+FGV SALCGMA SL ML+ FRV QGLAGGPLMPLSQTLLLRIFPKEKAAAA+GLW+MT Sbjct: 94 IMFGVCSALCGMATSLEMLVLFRVFQGLAGGPLMPLSQTLLLRIFPKEKAAAAIGLWSMT 153 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+AP+ GPILGGV+CD+ W YIF+INVPVALICGY+GW++LKRYE+ L++LPID VGL Sbjct: 154 TLVAPVMGPILGGVICDRLHWAYIFYINVPVALICGYLGWRLLKRYETGLMRLPIDAVGL 213 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+V+WV ALQ+MLDEGK+ DWFASTEI VL +IAA GF +FLIWELTER+P+VDLRVFR Sbjct: 214 ALLVVWVGALQIMLDEGKDNDWFASTEIRVLGIIAAIGFASFLIWELTERHPVVDLRVFR 273 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRG++ASV TI LAFGAFFGATVLTPLWLQ YMGYTAT +G TA+TGILAV++AP A Sbjct: 274 HRGFSASVVTITLAFGAFFGATVLTPLWLQNYMGYTATWAGCATAMTGILAVISAPLAAN 333 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 LS+R D R LVF GVMWLGA+TL R+ TDM+ +Q+ +PLL+ G+GLP FFVPLTGLAL Sbjct: 334 LSSRFDGRWLVFAGVMWLGAITLLRTHANTDMTFWQVAFPLLLQGVGLPFFFVPLTGLAL 393 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 SSV+E ETASAAGLM+FCRT GAIATSLVNT WE+++ Y AEL+G+VDQ G S L Sbjct: 394 SSVDEPETASAAGLMNFCRTFGGAIATSLVNTGWEDRTKYDRAELSGLVDQAGHFSTMLK 453 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKRVADTSAAH 480 +G S QA+A + ++QSQ++ML+TN +F MA F AA AVW APKP RVADTS AH Sbjct: 454 SSGFSASQAQAQISDIVQSQAVMLATNQLFTMAGACFIFAALAVWLAPKPTRVADTSQAH 513 >Q7P060.1 Q7P060_CHRVO Probable multidrug resistance protein Length = 514 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/480 (69%), Positives = 392/480 (81%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLDTTIANVSV I+G L SSSQGTYVITSYAVAEAI VPLTGWLA RFGTVR+F+ SM Sbjct: 35 VLDTTIANVSVPNIAGGLAVSSSQGTYVITSYAVAEAIIVPLTGWLAARFGTVRLFVGSM 94 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 +LFG+FS LCG+A SL L+ FRVLQGLAGGPLMP+SQTLLL+IFP++KA AA+GLW+MT Sbjct: 95 LLFGLFSMLCGLAGSLETLVLFRVLQGLAGGPLMPMSQTLLLQIFPRQKAGAAIGLWSMT 154 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+API GPILGG LCDQ SWP+IF+INVP+AL CG +GW++LKRY+S KL ID GL Sbjct: 155 TLVAPIMGPILGGTLCDQASWPWIFYINVPIALGCGLLGWRLLKRYQSQTAKLRIDAAGL 214 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+V+WV ALQLMLD+GKE DWF S IV LA+ A GF AFLIWELTE PIVDLRVFR Sbjct: 215 ALLVLWVGALQLMLDKGKELDWFGSPLIVGLAIAAVIGFAAFLIWELTEAQPIVDLRVFR 274 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRG+ ASV TI LAFG+FFGATVLTP WLQ YMGYTAT +G TA++G+LAV+ AP A+ Sbjct: 275 HRGFWASVLTISLAFGSFFGATVLTPQWLQAYMGYTATQAGYATAMSGVLAVMAAPIAAQ 334 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 LS+R+DPRKLVF GVMWLG VTL+RSF+TTDM +Q+ PLL G+G+P FFVPLTGLAL Sbjct: 335 LSSRLDPRKLVFCGVMWLGCVTLYRSFSTTDMGFWQVALPLLFQGLGMPFFFVPLTGLAL 394 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 +SVE +E ASAAGLMSF RT+SGA ATSLV T+W++K+ Y HAELAGMVD GD L+ Sbjct: 395 ASVEPAEVASAAGLMSFMRTLSGAFATSLVTTAWDDKASYNHAELAGMVDGGGDALRALS 454 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKRVADTSAAH 480 G+S A +EQ LQ+QS+MLSTN IF +A +SF +AA A+W AP+P RVADTS AH Sbjct: 455 AGGLSDGAAWGVIEQTLQAQSVMLSTNQIFWLAGLSFVVAACAIWLAPRPSRVADTSQAH 514 >F0LRP4.1 F0LRP4_VIBFU Multidrug resistance protein VceB Length = 511 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/480 (65%), Positives = 385/480 (80%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 +LDTTIANVSVS I+G+LG S+SQGTYVITSYAVAEAI+VPLTGWLA RFG++RVF+T Sbjct: 32 ILDTTIANVSVSNIAGSLGTSTSQGTYVITSYAVAEAISVPLTGWLARRFGSIRVFVTCF 91 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 +LFGVFS LCGMA S+ ML+ FRV G AGGPLMPLSQTL++RIFPK K+ AA+G+W+MT Sbjct: 92 LLFGVFSLLCGMATSMNMLVMFRVFLGFAGGPLMPLSQTLMIRIFPKNKSHAAIGIWSMT 151 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+API GPILGGVLCDQ+SWPYIFF+ P A++ + WK+LK++E+P IDKVGL Sbjct: 152 TLVAPIMGPILGGVLCDQFSWPYIFFVKTPFAIVAAILCWKLLKKFETPTAHSKIDKVGL 211 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L+V+WVAALQLMLDEGK+ DWF S+ IV LA+IAA GF+AFLIWELTERNP+VDL+VFR Sbjct: 212 ALLVVWVAALQLMLDEGKDHDWFESSRIVTLAVIAAVGFVAFLIWELTERNPVVDLKVFR 271 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRGY+ S+ T+ LAFGAFF +VLTPLWLQ YMGYTAT SG TA GILAV AP +A Sbjct: 272 HRGYSMSMVTLSLAFGAFFSISVLTPLWLQIYMGYTATISGHATATMGILAVFLAPIIAN 331 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 LS++ DPR VF+GVMWLG T RSFNT DM+ QI WP+ + GIG+PLFFVPLT +AL Sbjct: 332 LSSKYDPRPFVFVGVMWLGFWTFMRSFNTVDMTFEQISWPMFVQGIGMPLFFVPLTAIAL 391 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 SV+ E SAAGLM+F RT+SGA ATS++NTSWE++S Y HAELAG+ D+ G + + Sbjct: 392 GSVKVHEMESAAGLMNFIRTLSGAFATSMINTSWEHESRYVHAELAGLTDKAGVATQAMQ 451 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKRVADTSAAH 480 AGMS DQ R+ M+ MLQ QS+M++TN +F + A+ F +AA +WFAPKPK D SAAH Sbjct: 452 NAGMSADQTRSAMDWMLQGQSVMVATNQLFFVIAVIFAVAACMIWFAPKPKHAVDPSAAH 511 >B9YZQ5.1 B9YZQ5_9NEIS Drug resistance transporter, EmrB/QacA subfamily Length = 512 Score = 671 bits (1732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/480 (68%), Positives = 392/480 (81%) Query: 1 VLDTTIANVSVSTISGALGASSSQGTYVITSYAVAEAITVPLTGWLANRFGTVRVFITSM 60 VLDTTIANVSV I+G L S+SQGTYVITSYAVAEAI VPLTGWLA RFGTVR+F+ SM Sbjct: 33 VLDTTIANVSVPNIAGGLAVSASQGTYVITSYAVAEAIIVPLTGWLAARFGTVRLFVVSM 92 Query: 61 ILFGVFSALCGMANSLGMLIAFRVLQGLAGGPLMPLSQTLLLRIFPKEKAAAAVGLWAMT 120 +LFG+FS LCG ANS+ +L+ FRVLQGLAGGPLMP+SQTLL +IFPKEKA AA+GLW+MT Sbjct: 93 LLFGLFSVLCGFANSIELLVLFRVLQGLAGGPLMPMSQTLLQQIFPKEKAGAAIGLWSMT 152 Query: 121 TLIAPIAGPILGGVLCDQYSWPYIFFINVPVALICGYMGWKMLKRYESPLLKLPIDKVGL 180 TL+API GPILGG LCDQ W +IFFIN P+A+ C Y GW+MLKR+E L+KLP+D VGL Sbjct: 153 TLVAPIMGPILGGYLCDQVGWSWIFFINAPLAITCSYFGWQMLKRFEGKLIKLPVDAVGL 212 Query: 181 ILMVIWVAALQLMLDEGKEKDWFASTEIVVLALIAAAGFIAFLIWELTERNPIVDLRVFR 240 L++ WVAALQLMLDEGK DWF+S EIV+LA+IA GF AF+IWE+T NPIV+LRVFR Sbjct: 213 ALLIAWVAALQLMLDEGKNLDWFSSPEIVILAIIAVIGFAAFMIWEMTASNPIVNLRVFR 272 Query: 241 HRGYTASVTTICLAFGAFFGATVLTPLWLQGYMGYTATHSGETTALTGILAVLTAPFVAK 300 HRGY ASV TI LAFG+FFGATVLTP WLQ YMGYTAT +G TA++GILAV+ AP A+ Sbjct: 273 HRGYWASVLTISLAFGSFFGATVLTPQWLQSYMGYTATQAGYATAMSGILAVIAAPIAAQ 332 Query: 301 LSTRVDPRKLVFIGVMWLGAVTLFRSFNTTDMSNFQIGWPLLMLGIGLPLFFVPLTGLAL 360 +ST++DPR LVF GVMWLG VTLFRSF T+DM +Q+ PLL G+G+P FFVPLTGLA+ Sbjct: 333 MSTKMDPRPLVFFGVMWLGGVTLFRSFGTSDMGFWQVALPLLFQGVGMPFFFVPLTGLAM 392 Query: 361 SSVEESETASAAGLMSFCRTMSGAIATSLVNTSWENKSIYYHAELAGMVDQFGDVSNTLA 420 +SVE E ASAAGLMSF RT+SGA ATSLV TSWE+K+ Y AEL+G VD G V L Sbjct: 393 ASVETEEMASAAGLMSFLRTLSGAFATSLVTTSWEDKASYNRAELSGFVDSTGQVLQGLT 452 Query: 421 QAGMSLDQARANMEQMLQSQSIMLSTNHIFMMAAISFGLAAAAVWFAPKPKRVADTSAAH 480 Q+GMS + AR ++Q++QSQSIMLSTN IF ++ +SF +AA A+W AP+P +VADTS H Sbjct: 453 QSGMSAETARGMIDQLVQSQSIMLSTNQIFWLSGLSFVIAACAIWLAPRPTKVADTSNVH 512