BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0099.p (426 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0T6.1 D8J0T6_HERSS HD-GYP domain metal-dependent phosphohydro... 501 e-139 D8J0Q8.1 D8J0Q8_HERSS HD-GYP domain containing protein 466 e-129 D8ISQ0.1 D8ISQ0_HERSS HD-GYP domain protein 423 e-116 C9YFN1.1 C9YFN1_9BURK Putative uncharacterized protein 401 e-109 E8TUH7.1 E8TUH7_ALIDB Metal dependent phosphohydrolase 399 e-109 >D8J0T6.1 D8J0T6_HERSS HD-GYP domain metal-dependent phosphohydrolase protein EC=3.1.3.- Length = 406 Score = 501 bits (1289), Expect = e-139, Method: Compositional matrix adjust. Identities = 238/420 (56%), Positives = 308/420 (73%), Gaps = 19/420 (4%) Query: 3 LLKKIKVDELELGMYFCGFEAAWLDHPFWKNRFLLKDTAHLQQARASGIAYCWIDVGQGK 62 +LKKIKV++L LGMYFCGFEAAWLDHPFWKN+FLLK+ + L+QA ASGIAYCWID +G Sbjct: 1 MLKKIKVEDLVLGMYFCGFEAAWLDHPFWKNKFLLKNDSELRQAHASGIAYCWIDTERGL 60 Query: 63 DVAAAEQDADVAAE-SEAESGVESGVESEGAETALSLRDELPVAVGADPFFEELEQAQRL 121 DVA E+ AD AA E E E P A P L A L Sbjct: 61 DVAQEEEAADSAAPLQETEPSPE------------------PEHAAAPPIDAVLLDAMAL 102 Query: 122 CETAKDATKAMFADIRMGRVIDMERCLDLVDQVTASILRNSAAMTSIVRLKLADDYTYMH 181 ETAK ATKAMF++ RMG+V+DMERC+ +V+++ S++++ S++RLKLAD+YTY+H Sbjct: 103 RETAKKATKAMFSEARMGKVLDMERCVSVVEEIAGSVIKSPNGALSVLRLKLADEYTYLH 162 Query: 182 SVAVCTLMVALGRTIGMDEPACKEAGLSGLLHDVGKAFIPVPILHKPGGLTPAEIDIVRR 241 SVAVC LMVALGRT+G+DE AC+EAGL G LHDVGKAFIP +L+KPG L+ E +++ Sbjct: 163 SVAVCALMVALGRTLGLDETACREAGLGGFLHDVGKAFIPHELLNKPGKLSDEEFSQIKK 222 Query: 242 HPVLGYNHLIKNSNIPPYAVEVCLHHHEKINGTGYPDGLSGAGISLLSRMASICDVYDAV 301 HP LGY +L ++ N+P YA +VCLHHHEKI+G GYP+GL I+L SRMA+ICDVYDA+ Sbjct: 223 HPELGYKYLSQDPNVPDYARDVCLHHHEKIDGNGYPEGLRAGAITLYSRMAAICDVYDAL 282 Query: 302 TSDRPYKKGWDPAESLTAMASWSGHFDKTLLSAFVKTLGIYPIGSLLKMESGRLGLVIRQ 361 TSDRPYK+ WDPAE+++AMASW+GHFD+ + AFVKTLGIYP+GS++K+ESGR G VIRQ Sbjct: 283 TSDRPYKRAWDPAEAISAMASWTGHFDRAMFLAFVKTLGIYPVGSIVKLESGRSGFVIRQ 342 Query: 362 SAAGLTKPVVKAFRYDSNGDIIDSEIIDLSDPAASDSIRQRGGEEWLKYNGLNKLWMQPT 421 +A LT+PV+K F YD + + D+EI+DL +D+I RGGEEW + + L+ + + T Sbjct: 343 NAQDLTRPVLKVFHYDDSMTVTDTEILDLLANPEADTIVARGGEEWARLSHLDAMQLLST 402 >D8J0Q8.1 D8J0Q8_HERSS HD-GYP domain containing protein Length = 408 Score = 466 bits (1198), Expect = e-129, Method: Compositional matrix adjust. Identities = 222/413 (53%), Positives = 291/413 (70%), Gaps = 25/413 (6%) Query: 1 MSLLKKIKVDELELGMYFCGFEAAWLDHPFWKNRFLLKDTAHLQQARASGIAYCWIDVGQ 60 M+ LKKI+V +L +GMYF GF+ AW+D PFW+ FL++ + + +ARA+G YCWID Q Sbjct: 1 MTRLKKIEVGQLSVGMYFSGFDGAWIDTPFWRTSFLVRKASEIARARAAGYTYCWIDTDQ 60 Query: 61 GKDVAAAEQDADVAAESEAESGVESGVESEGAETALSLRDELPVAVGADPFFEELEQAQR 120 G D+A AE AD E+E P A G+ EL+ A R Sbjct: 61 GIDLAGAE--ADRLPETEE-----------------------PEAAGSSSSRSELDDALR 95 Query: 121 LCETAKDATKAMFADIRMGRVIDMERCLDLVDQVTASILRNSAAMTSIVRLKLADDYTYM 180 L E AK T+ MF R+G+ +D+E C LV+++ S+ R+S A+ SI+RLK D+YTY+ Sbjct: 96 LYENAKQTTQQMFKQARLGKTLDVENCKSLVEEIATSVARDSNALLSIIRLKRVDEYTYL 155 Query: 181 HSVAVCTLMVALGRTIGMDEPACKEAGLSGLLHDVGKAFIPVPILHKPGGLTPAEIDIVR 240 HS+AVCTLMVAL RT+GMD+ ACKEAGL+G LHDVGKAFIP+ IL+KP L+ E I++ Sbjct: 156 HSIAVCTLMVALARTLGMDDIACKEAGLAGYLHDVGKAFIPLEILNKPDRLSEQEYKIIQ 215 Query: 241 RHPVLGYNHLIKNSNIPPYAVEVCLHHHEKINGTGYPDGLSGAGISLLSRMASICDVYDA 300 RHP LGY++L S +P Y ++VCLHHHEKI+G+GYP G IS+ SRMA++CDVYDA Sbjct: 216 RHPALGYDYLKGFSGVPDYVLDVCLHHHEKIDGSGYPSRHQGNQISVYSRMAAVCDVYDA 275 Query: 301 VTSDRPYKKGWDPAESLTAMASWSGHFDKTLLSAFVKTLGIYPIGSLLKMESGRLGLVIR 360 VTS+RPYK GWDPAESL+ MASW GHFD+ + AFVK LGIYPIGS++K++SGR LVIR Sbjct: 276 VTSERPYKSGWDPAESLSRMASWQGHFDRPIFLAFVKALGIYPIGSIVKLQSGRTALVIR 335 Query: 361 QSAAGLTKPVVKAFRYDSNGDIIDSEIIDLSDPAASDSIRQRGGEEWLKYNGL 413 Q+ LTKPVVKAF + ++++SEIIDLS P +D+I +R G++WLK NGL Sbjct: 336 QNHVDLTKPVVKAFVTTPSIEVVESEIIDLSAPGQTDAIAERSGQDWLKSNGL 388 >D8ISQ0.1 D8ISQ0_HERSS HD-GYP domain protein Length = 410 Score = 423 bits (1087), Expect = e-116, Method: Compositional matrix adjust. Identities = 206/411 (50%), Positives = 284/411 (69%), Gaps = 28/411 (6%) Query: 3 LLKKIKVDELELGMYFCGFEAAWLDHPFWKNRFLLKDTAHLQQARASGIAYCWIDVGQGK 62 +LKKIKV +L LGMYFCGFEA+WL HPFWK RFLL + LQQARASGIAYCWIDV +G+ Sbjct: 1 MLKKIKVGDLVLGMYFCGFEASWLAHPFWKTRFLLSRESDLQQARASGIAYCWIDVSRGR 60 Query: 63 DVAAAEQDADVAAES----EAESGVESGVESEGAETALSLRDELPVAVGADPFFEELEQA 118 DVA A AA + + + +G +++ A +A++LR Sbjct: 61 DVAGAAPAKAEAAAAPASPDQSAATHAGADADRA-SAVALR------------------- 100 Query: 119 QRLCETAKDATKAMFADIRMGRVIDMERCLDLVDQVTASILRNSAAMTSIVRLKLADDYT 178 E A++ T+ MF RMG+++++ +C+ LV+++ S+LR+ + S++RLKL D+YT Sbjct: 101 ----EHAREVTRQMFNAARMGKMVELPQCVALVEEIACSVLRDPNGLLSVLRLKLNDEYT 156 Query: 179 YMHSVAVCTLMVALGRTIGMDEPACKEAGLSGLLHDVGKAFIPVPILHKPGGLTPAEIDI 238 Y+HSV+VC L++ LGRT+G+ E AC+EAGLSG LHDVGKAFI IL+KPG LT E + Sbjct: 157 YLHSVSVCALVIGLGRTLGLSEAACREAGLSGYLHDVGKAFIDDEILNKPGKLTAEEFAL 216 Query: 239 VRRHPVLGYNHLIKNSNIPPYAVEVCLHHHEKINGTGYPDGLSGAGISLLSRMASICDVY 298 ++RHP LGY +LI+ ++P YA +VC HHHE+++G GYPD L I+L +RM ++CDVY Sbjct: 217 IKRHPELGYQYLIQTPDMPAYASDVCRHHHERLDGRGYPDALPAESITLYARMTAVCDVY 276 Query: 299 DAVTSDRPYKKGWDPAESLTAMASWSGHFDKTLLSAFVKTLGIYPIGSLLKMESGRLGLV 358 DA+TS+RPYK GWDPAE+++ MA W GHFD+ LL AFVKTLGIYP+GSL+++ESG G+V Sbjct: 277 DALTSERPYKHGWDPAEAISQMARWEGHFDRRLLLAFVKTLGIYPVGSLVRLESGVSGVV 336 Query: 359 IRQSAAGLTKPVVKAFRYDSNGDIIDSEIIDLSDPAASDSIRQRGGEEWLK 409 IRQ+ A LT+PV+K + ++DL +D+I RG EEW + Sbjct: 337 IRQNPADLTRPVLKVLHLQGPHETTIGGVLDLMAWPRTDTIIGRGDEEWTR 387 >C9YFN1.1 C9YFN1_9BURK Putative uncharacterized protein Length = 412 Score = 401 bits (1030), Expect = e-109, Method: Compositional matrix adjust. Identities = 200/416 (48%), Positives = 274/416 (65%), Gaps = 13/416 (3%) Query: 3 LLKKIKVDELELGMYFCGFEAAWLDHPFWKNRFLLKDTAHLQQARASGIAYCWIDVGQGK 62 +LKKI V++L +GM+ F +W++HPFW++ F++ D + RAS I WID G+G Sbjct: 1 MLKKIAVEQLVVGMHLKEFCGSWMEHPFWRSGFVITDPKDITTIRASAIREVWIDCGKGL 60 Query: 63 DVAAAEQDADVAAESEAESGVESGVESEGAETALSLRDELPVAVGADPFFEELEQAQRLC 122 DVA E A SE++S E VE+E E S RD P++V EEL +A ++C Sbjct: 61 DVAVGE-----TAVSESDS--EEQVEAELREAVSSSRDVAPLSVQ-----EELARAAKIC 108 Query: 123 ETAKDATKAMFADIRMGRVIDMERCLDLVDQVTASILRNSAAMTSIVRLKLADDYTYMHS 182 +K A +MF + RMG+ +D LV ++T S+ RN A+ S+ RLK ADDYTYMHS Sbjct: 109 HQSKQAVLSMFQEARMGKTVDTGGAKQLVQEITDSVTRNPGALISLARLKTADDYTYMHS 168 Query: 183 VAVCTLMVALGRTIGMDEPACKEAGLSGLLHDVGKAFIPVPILHKPGGLTPAEIDIVRRH 242 VAVC +MVAL + +G+ E + AG++GL+HD+GKA +P+ +L+KPG LT AE I+++H Sbjct: 169 VAVCAMMVALAKQLGLSEEETRSAGIAGLMHDLGKAAMPMDVLNKPGKLTDAEFAIIKKH 228 Query: 243 PVLGYNHLIKNSNIPPYAVEVCLHHHEKINGTGYPDGLSGAGISLLSRMASICDVYDAVT 302 P GY L + + P ++VCLHHHEK++G+GYP GL G ISL ++M ++CDVYDA+T Sbjct: 229 PEEGYRLLQTGNAVDPMVLDVCLHHHEKVDGSGYPKGLKGEQISLFAKMGAVCDVYDAIT 288 Query: 303 SDRPYKKGWDPAESLTAMASW-SGHFDKTLLSAFVKTLGIYPIGSLLKMESGRLGLVIRQ 361 S+RPYK GWDPAESL MA W SGHFD + AFVK+LGIYPIGSL+++ SGRLG+V+ Q Sbjct: 289 SNRPYKSGWDPAESLRKMAEWASGHFDGKVFQAFVKSLGIYPIGSLVQLSSGRLGVVVEQ 348 Query: 362 SAAGLTKPVVKAFRYDSNGDIIDSEIIDLSDPAASDSIRQRGGEEWLKYNGLNKLW 417 +A LT P VK F + I EI+DLS P SD I R K+ L++LW Sbjct: 349 TAKSLTTPCVKVFYSTKSHMRIVPEIVDLSRPGNSDKIVSREDPAKWKFPDLDELW 404 >E8TUH7.1 E8TUH7_ALIDB Metal dependent phosphohydrolase Length = 421 Score = 399 bits (1024), Expect = e-109, Method: Compositional matrix adjust. Identities = 208/423 (49%), Positives = 278/423 (65%), Gaps = 18/423 (4%) Query: 3 LLKKIKVDELELGMYFCGFEAAWLDHPFWKNRFLLKDTAHLQQARASGIAYCWIDVGQGK 62 +LK+I V L LGMY F +W++HPFW++RFLL D L R + I WIDV +G Sbjct: 1 MLKRIDVRHLVLGMYLHEFCGSWMEHPFWRSRFLLTDPKDLALIRKTNIREVWIDVSKGL 60 Query: 63 DVAAAEQDADVAAESEAESGVESGVESEGAETALSLRDELPVAVGAD------PFFEELE 116 DV A V+ E E ++ VES + G A ELP+ +G D +EL Sbjct: 61 DVTPGT--AAVSRE-EVDAQVESELHHAGNNQA-----ELPIDLGKDDALKPSAMSDELR 112 Query: 117 QAQRLCETAKDATKAMFADIRMGRVIDMERCLDLVDQVTASILRNSAAMTSIVRLKLADD 176 +A +C +AK A +MF + RMGR +D + +VD+++ S++RN A+ S+ RLK ADD Sbjct: 113 RAASICASAKKAVVSMFTEARMGRALDTQTAQGMVDEISDSVMRNPGALISLARLKTADD 172 Query: 177 YTYMHSVAVCTLMVALGRTIGMDEPACKEAGLSGLLHDVGKAFIPVPILHKPGGLTPAEI 236 YTYMHSVAVC LMVAL R IGMDE A + AGL+GLLHD+GKA IP+ IL+KPG LT E Sbjct: 173 YTYMHSVAVCALMVALARQIGMDEQATRLAGLAGLLHDLGKAAIPLHILNKPGKLTDEEF 232 Query: 237 DIVRRHPVLGYNHLIKNSNIPPYAVEVCLHHHEKINGTGYPDGLSGAGISLLSRMASICD 296 I+R HP G++ +++ S++ P ++ CLHHHEKI+GTGYP L G+ IS+L+RMA+ICD Sbjct: 233 AIIRSHPEAGHS-MLQPSSVHPAVLDACLHHHEKIDGTGYPHRLKGSEISVLARMAAICD 291 Query: 297 VYDAVTSDRPYKKGWDPAESLTAMASWS-GHFDKTLLSAFVKTLGIYPIGSLLKMESGRL 355 VYDA+TSDRPYK GWDP+ESL MA W+ HFD LL AFVKT+GIYP+GSL+++ SGRL Sbjct: 292 VYDAITSDRPYKNGWDPSESLRRMAEWTHDHFDGRLLQAFVKTIGIYPVGSLVRLASGRL 351 Query: 356 GLVIRQSAAGLTKPVVKAFRYDSNGDI-IDSEIIDLSDPAASDSIRQRGGEEWLKYNGLN 414 G+V Q+ L P VK F + + D+ I EI+DLS P ++ I R + LN Sbjct: 352 GVVTEQNGGSLLAPRVKVF-FSTKSDLRIPPEIVDLSAPGCAEKIVGRENPAQWNFPDLN 410 Query: 415 KLW 417 ++W Sbjct: 411 EIW 413