BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0054.p (355 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4G494.1 A4G494_HERAR dTDP-glucose 4,6-dehydratase EC=4.2.1.46 576 e-162 Q2SYI4.1 Q2SYI4_BURTA dTDP-glucose 4,6-dehydratase EC=4.2.1.46 565 e-159 B1YU34.1 B1YU34_BURA4 dTDP-glucose 4,6-dehydratase EC=4.2.1.46 561 e-158 B9BCR2.1 B9BCR2_9BURK dTDP-glucose 4,6-dehydratase EC=4.2.1.46 560 e-157 A4ME89.1 A4ME89_BURPS dTDP-glucose 4,6-dehydratase EC=4.2.1.46 559 e-157 >A4G494.1 A4G494_HERAR dTDP-glucose 4,6-dehydratase EC=4.2.1.46 Length = 367 Score = 576 bits (1484), Expect = e-162, Method: Compositional matrix adjust. Identities = 269/350 (76%), Positives = 302/350 (86%), Gaps = 1/350 (0%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIGSNF+LD+L++ DE V+N+DKLTYAGNP NL SL D R+ FV AD+ D Sbjct: 1 MILVTGGAGFIGSNFVLDWLAQSDEPVVNVDKLTYAGNPNNLASLRDDTRHIFVHADICD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 K+ EL S ++P AI+HFAAESHVDRSIH P EF+ TN+NGTF+LLE AR YW L + Sbjct: 61 SDKMQELLSTYKPTAIVHFAAESHVDRSIHGPAEFVRTNINGTFSLLEAARTYWPQLTSA 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 ++++FRFLHVSTDEVYGTLG DDAPFSETT YAPNSPYSASKAASDHLVR+YHHTYGLPT Sbjct: 121 EKEQFRFLHVSTDEVYGTLGPDDAPFSETTAYAPNSPYSASKAASDHLVRSYHHTYGLPT 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPYHFPEKLIPL+I NAL GKPLPIYGDGQQIRDWL+VGDHCTAIR VL Sbjct: 181 LTTNCSNNYGPYHFPEKLIPLIIANALAGKPLPIYGDGQQIRDWLYVGDHCTAIRRVLQA 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAG-SYRDQITFVQDRPGHDRRYAID 299 G PGETYNIGGWNEKANLDVV TLCDMLD L+P AG SYR QIT+V DRPGHDRRYAID Sbjct: 241 GKPGETYNIGGWNEKANLDVVNTLCDMLDALQPNGAGSSYRKQITYVADRPGHDRRYAID 300 Query: 300 ARKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQY 349 ARK+ERELGWKPAETF++GI KTV+WYL+N WV +V+SG Y+KWLE Y Sbjct: 301 ARKIERELGWKPAETFDSGIRKTVQWYLENQAWVRDVQSGDYMKWLEKNY 350 >Q2SYI4.1 Q2SYI4_BURTA dTDP-glucose 4,6-dehydratase EC=4.2.1.46 Length = 397 Score = 565 bits (1456), Expect = e-159, Method: Compositional matrix adjust. Identities = 262/352 (74%), Positives = 298/352 (84%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L++ DE VLN+DKLTYAGN L SL G+ ++ F + D+ D Sbjct: 45 MILVTGGAGFIGANFVLDWLAQSDEAVLNVDKLTYAGNLGTLKSLQGNPKHVFARVDICD 104 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A I L ++++PRAILHFAAESHVDRSIH P +F+ TNV GTF LLE AR YWS L+A Sbjct: 105 RAAIDALLAQYKPRAILHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARQYWSALDAD 164 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 + FRFLHVSTDEV+G+L D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLPT Sbjct: 165 AKAAFRFLHVSTDEVFGSLSPADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPT 224 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GKPLP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 225 LTTNCSNNYGPYQFPEKLIPLMIANALGGKPLPVYGDGQNVRDWLYVGDHCSAIREVLAR 284 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NLDVV TLCD+LDE +PKAAGSYRDQIT+V DRPGHDRRYAIDA Sbjct: 285 GVPGETYNVGGWNEKKNLDVVHTLCDLLDEARPKAAGSYRDQITYVTDRPGHDRRYAIDA 344 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTVRWYLD+ +WV V SG Y KW+E Y + Sbjct: 345 RKLERELGWKPAETFETGLAKTVRWYLDSQEWVDEVASGDYRKWVETNYAQR 396 >B1YU34.1 B1YU34_BURA4 dTDP-glucose 4,6-dehydratase EC=4.2.1.46 Length = 353 Score = 561 bits (1445), Expect = e-158, Method: Compositional matrix adjust. Identities = 261/352 (74%), Positives = 295/352 (83%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L + DE VLN+DKLTYAGN L SLDG ++ FV+AD+ D Sbjct: 1 MILVTGGAGFIGANFVLDWLRQSDEAVLNVDKLTYAGNLRTLQSLDGSPKHVFVRADICD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A + LF+ ++PRA+LHFAAESHVDRSIH P EF+ TNV GTF LLE AR YW+ L Sbjct: 61 RAALDALFAEYQPRAVLHFAAESHVDRSIHGPAEFVQTNVVGTFTLLEAARTYWNGLNEA 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 R FRFLHVSTDEV+G+L + D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLPT Sbjct: 121 DRSAFRFLHVSTDEVFGSLSAADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPT 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GK LP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 181 LTTNCSNNYGPYQFPEKLIPLMIANALAGKALPVYGDGQNVRDWLYVGDHCSAIREVLAR 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NL+VV TLCD+LD+ +PKAAGSYRDQIT+V DRPGHDRRYAIDA Sbjct: 241 GVPGETYNVGGWNEKKNLEVVHTLCDLLDQARPKAAGSYRDQITYVTDRPGHDRRYAIDA 300 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTV WYLDN WV V SG Y KW+E Y + Sbjct: 301 RKLERELGWKPAETFETGLAKTVAWYLDNQVWVDEVASGEYRKWVETNYAAR 352 >B9BCR2.1 B9BCR2_9BURK dTDP-glucose 4,6-dehydratase EC=4.2.1.46 Length = 371 Score = 560 bits (1443), Expect = e-157, Method: Compositional matrix adjust. Identities = 259/352 (73%), Positives = 294/352 (83%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L DE VLN+DKLTYAGN L SL+G+ ++ F + D+ D Sbjct: 19 MILVTGGAGFIGANFVLDWLRASDEAVLNVDKLTYAGNLRTLQSLEGNPKHVFARVDICD 78 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A + LF+ H+PRA+LHFAAESHVDRSIH P +F+ TNV GTF LLE AR YW+ L Sbjct: 79 RAALDALFAEHKPRAVLHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARQYWNGLNDA 138 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 + FRFLHVSTDEV+G+L + D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLPT Sbjct: 139 DKAAFRFLHVSTDEVFGSLSATDPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPT 198 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GKPLP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 199 LTTNCSNNYGPYQFPEKLIPLMIANALAGKPLPVYGDGQNVRDWLYVGDHCSAIREVLAR 258 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NL+VV TLCD+LD +PKAAGSYRDQIT+V DRPGHDRRYAIDA Sbjct: 259 GVPGETYNVGGWNEKKNLEVVHTLCDLLDSKRPKAAGSYRDQITYVTDRPGHDRRYAIDA 318 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTV WYLDN QWV V SG Y KW+E Y + Sbjct: 319 RKLERELGWKPAETFETGLAKTVDWYLDNQQWVDEVASGEYRKWVETNYAQR 370 >A4ME89.1 A4ME89_BURPS dTDP-glucose 4,6-dehydratase EC=4.2.1.46 Length = 353 Score = 559 bits (1440), Expect = e-157, Method: Compositional matrix adjust. Identities = 260/352 (73%), Positives = 295/352 (83%) Query: 1 MIFVTGGAGFIGSNFILDYLSRHDEHVLNIDKLTYAGNPYNLGSLDGDARYHFVQADVAD 60 MI VTGGAGFIG+NF+LD+L++ DE VLN+DKLTYAGN L SL G+ ++ F + D+ D Sbjct: 1 MILVTGGAGFIGANFVLDWLAQSDEAVLNVDKLTYAGNLGTLKSLQGNPKHVFARVDICD 60 Query: 61 HAKIAELFSRHRPRAILHFAAESHVDRSIHSPGEFIHTNVNGTFNLLEVARHYWSDLEAQ 120 A I L ++H+PRAI+HFAAESHVDRSIH P +F+ TNV GTF LLE ARHYWS L Sbjct: 61 RAAIDALLAQHKPRAIVHFAAESHVDRSIHGPADFVQTNVVGTFTLLEAARHYWSALGPD 120 Query: 121 QRQEFRFLHVSTDEVYGTLGSDDAPFSETTPYAPNSPYSASKAASDHLVRAYHHTYGLPT 180 + FRFLHVSTDEV+G+L D FSETTPYAPNSPYSA+KA SDHLVRAYHHTYGLP Sbjct: 121 AKAAFRFLHVSTDEVFGSLSPADPQFSETTPYAPNSPYSATKAGSDHLVRAYHHTYGLPV 180 Query: 181 LTTNCSNNYGPYHFPEKLIPLVILNALDGKPLPIYGDGQQIRDWLFVGDHCTAIREVLAR 240 LTTNCSNNYGPY FPEKLIPL+I NAL GKPLP+YGDGQ +RDWL+VGDHC+AIREVLAR Sbjct: 181 LTTNCSNNYGPYQFPEKLIPLMIANALGGKPLPVYGDGQNVRDWLYVGDHCSAIREVLAR 240 Query: 241 GVPGETYNIGGWNEKANLDVVRTLCDMLDELKPKAAGSYRDQITFVQDRPGHDRRYAIDA 300 GVPGETYN+GGWNEK NLDVV TLCD+LDE +PKA GSYRDQIT+V DRPGHDRRYAIDA Sbjct: 241 GVPGETYNVGGWNEKKNLDVVHTLCDLLDEARPKAGGSYRDQITYVTDRPGHDRRYAIDA 300 Query: 301 RKLERELGWKPAETFETGIAKTVRWYLDNPQWVANVRSGGYLKWLELQYGGK 352 RKLERELGWKPAETFETG+AKTVRWYLD+ +WV V SG Y KW+E Y + Sbjct: 301 RKLERELGWKPAETFETGLAKTVRWYLDHQEWVDEVVSGDYRKWVETNYAQR 352