BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0053.p (336 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVR8.1 D8IVR8_HERSS UDP-glucose 4-epimerase protein EC=5.1.3.2 534 e-150 C3V130.1 C3V130_HERSE GalE EC=5.1.3.2 534 e-150 Q0AEX1.1 Q0AEX1_NITEC UDP-galactose 4-epimerase EC=5.1.3.2 509 e-142 Q47GN9.1 Q47GN9_DECAR UDP-galactose 4-epimerase EC=5.1.3.2 501 e-140 Q82WJ5.1 Q82WJ5_NITEU NAD dependent epimerase/dehydratase family... 495 e-138 >D8IVR8.1 D8IVR8_HERSS UDP-glucose 4-epimerase protein EC=5.1.3.2 Length = 336 Score = 534 bits (1376), Expect = e-150, Method: Compositional matrix adjust. Identities = 250/335 (74%), Positives = 292/335 (87%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHQVVVFDNFCNSFPESVRRVEKITGKTLALVEGDIR 60 MNILVTGGAGYIGSHTCVELLKAGH+V+VFDNFCNS PESV+RV++ITGKTL+LV+GDIR Sbjct: 1 MNILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIR 60 Query: 61 DREALEKALRSYECDAVIHFAGLKAVGESVAKPLEYYDNNVVGTVRLLEAMQATGVKTIV 120 +RE LE LR ++C+AVIHFAGLKAVGESV +PL YYDNNVVGTVRLLEAMQATGVKTIV Sbjct: 61 NREQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIV 120 Query: 121 FSSSATVYGVPQFLPYTEDHPLSSTSPYGRGKLMVEDILRDYHVAQPDSRIALLRYFNPV 180 FSSSATVYG PQ+LP E HPLS+++PYGR K+++ED+LRDY+ A PD +IALLRYFNPV Sbjct: 121 FSSSATVYGDPQYLPLDEAHPLSASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNPV 180 Query: 181 GAHHSGLIGEDPQGVPNNLMPFVTQVAIGKRDRLQIWGGDYDTHDGTGVRDYIHVEDLAV 240 GAH SGLIGEDP G+PNNLMPFV QVAIG+R+RL IWGGDY T DGTGVRD+IHV DLA Sbjct: 181 GAHESGLIGEDPGGIPNNLMPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLAR 240 Query: 241 GHVKALEHLRQPQCFAVNLGSGRGHSVLEVVKAFEQACGKSIPYEIGPRRAGDLPAYYAD 300 GHV AL+ L PQCFAVNLG+G G+SVL+V+KA+E+ACGK++PY I RR GD+ + YA+ Sbjct: 241 GHVAALQALDAPQCFAVNLGTGVGYSVLDVLKAYEKACGKTLPYAIAERRPGDIASCYAN 300 Query: 301 VTLAKSLLGWKATRSLETMCADSWRWQQANPDGFR 335 AK LGW+AT LE MCADSW+WQQ NP+GF+ Sbjct: 301 PAEAKRKLGWEATLGLEAMCADSWKWQQMNPNGFK 335 >C3V130.1 C3V130_HERSE GalE EC=5.1.3.2 Length = 336 Score = 534 bits (1376), Expect = e-150, Method: Compositional matrix adjust. Identities = 250/335 (74%), Positives = 292/335 (87%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHQVVVFDNFCNSFPESVRRVEKITGKTLALVEGDIR 60 MNILVTGGAGYIGSHTCVELLKAGH+V+VFDNFCNS PESV+RV++ITGKTL+LV+GDIR Sbjct: 1 MNILVTGGAGYIGSHTCVELLKAGHEVIVFDNFCNSSPESVKRVQQITGKTLSLVKGDIR 60 Query: 61 DREALEKALRSYECDAVIHFAGLKAVGESVAKPLEYYDNNVVGTVRLLEAMQATGVKTIV 120 +RE LE LR ++C+AVIHFAGLKAVGESV +PL YYDNNVVGTVRLLEAMQATGVKTIV Sbjct: 61 NREQLESVLREFKCEAVIHFAGLKAVGESVEQPLMYYDNNVVGTVRLLEAMQATGVKTIV 120 Query: 121 FSSSATVYGVPQFLPYTEDHPLSSTSPYGRGKLMVEDILRDYHVAQPDSRIALLRYFNPV 180 FSSSATVYG PQ+LP E HPLS+++PYGR K+++ED+LRDY+ A PD +IALLRYFNPV Sbjct: 121 FSSSATVYGDPQYLPLDEAHPLSASNPYGRSKIVIEDMLRDYYRAHPDWKIALLRYFNPV 180 Query: 181 GAHHSGLIGEDPQGVPNNLMPFVTQVAIGKRDRLQIWGGDYDTHDGTGVRDYIHVEDLAV 240 GAH SGLIGEDP G+PNNLMPFV QVAIG+R+RL IWGGDY T DGTGVRD+IHV DLA Sbjct: 181 GAHESGLIGEDPGGIPNNLMPFVAQVAIGRRERLNIWGGDYPTPDGTGVRDFIHVVDLAR 240 Query: 241 GHVKALEHLRQPQCFAVNLGSGRGHSVLEVVKAFEQACGKSIPYEIGPRRAGDLPAYYAD 300 GHV AL+ L PQCFAVNLG+G G+SVL+V+KA+E+ACGK++PY I RR GD+ + YA+ Sbjct: 241 GHVAALQALDAPQCFAVNLGTGVGYSVLDVLKAYEKACGKTLPYAIAERRPGDIASCYAN 300 Query: 301 VTLAKSLLGWKATRSLETMCADSWRWQQANPDGFR 335 AK LGW+AT LE MCADSW+WQQ NP+GF+ Sbjct: 301 PAEAKRKLGWEATLGLEAMCADSWKWQQMNPNGFK 335 >Q0AEX1.1 Q0AEX1_NITEC UDP-galactose 4-epimerase EC=5.1.3.2 Length = 335 Score = 509 bits (1312), Expect = e-142, Method: Compositional matrix adjust. Identities = 235/334 (70%), Positives = 276/334 (82%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHQVVVFDNFCNSFPESVRRVEKITGKTLALVEGDIR 60 M +LVTGGAGYIGSHTCVELL AG++VVVFDNFCNS PE++RRVEKITGK LA+V GD+R Sbjct: 1 MKVLVTGGAGYIGSHTCVELLTAGYEVVVFDNFCNSHPEALRRVEKITGKKLAVVRGDVR 60 Query: 61 DREALEKALRSYECDAVIHFAGLKAVGESVAKPLEYYDNNVVGTVRLLEAMQATGVKTIV 120 D+ +EK L+ Y C+AVIHFAGLKAVGESV KPLEYYDNNV+ T+RLL AMQ V T+V Sbjct: 61 DQATIEKVLKDYHCEAVIHFAGLKAVGESVEKPLEYYDNNVISTLRLLAAMQNCAVYTLV 120 Query: 121 FSSSATVYGVPQFLPYTEDHPLSSTSPYGRGKLMVEDILRDYHVAQPDSRIALLRYFNPV 180 FSSSATVYG PQ LP TEDHPLS+T+PYGR KLM+E++LRD + A P RIA+LRYFNPV Sbjct: 121 FSSSATVYGEPQRLPLTEDHPLSATNPYGRSKLMIEEMLRDVYRANPQFRIAILRYFNPV 180 Query: 181 GAHHSGLIGEDPQGVPNNLMPFVTQVAIGKRDRLQIWGGDYDTHDGTGVRDYIHVEDLAV 240 GAH SGLIGEDPQG+PNNLMPFV QVA+G+R+ L +WG DY THDGTGVRDYIHV DLA+ Sbjct: 181 GAHDSGLIGEDPQGIPNNLMPFVAQVAVGRREHLNVWGSDYPTHDGTGVRDYIHVVDLAL 240 Query: 241 GHVKALEHLRQPQCFAVNLGSGRGHSVLEVVKAFEQACGKSIPYEIGPRRAGDLPAYYAD 300 GH+ AL HL PQC AVNLG+G G+SVL+VVKAFE A G+ +PY++ PRRAGD+ YAD Sbjct: 241 GHLSALGHLATPQCLAVNLGTGTGYSVLDVVKAFENASGQHVPYQLSPRRAGDVATCYAD 300 Query: 301 VTLAKSLLGWKATRSLETMCADSWRWQQANPDGF 334 LA+ +L W A R L MC D WRWQ+ NP+G+ Sbjct: 301 PALAEKILEWNAQRDLAAMCRDHWRWQKCNPEGY 334 >Q47GN9.1 Q47GN9_DECAR UDP-galactose 4-epimerase EC=5.1.3.2 Length = 334 Score = 501 bits (1291), Expect = e-140, Method: Compositional matrix adjust. Identities = 232/333 (69%), Positives = 274/333 (82%) Query: 3 ILVTGGAGYIGSHTCVELLKAGHQVVVFDNFCNSFPESVRRVEKITGKTLALVEGDIRDR 62 ILVTGGAGYIGSHTCVELL +G VVVFDNFCNS PES++RVE ITGK +A+V+GDIRD+ Sbjct: 2 ILVTGGAGYIGSHTCVELLNSGQDVVVFDNFCNSHPESIKRVEAITGKKIAVVKGDIRDQ 61 Query: 63 EALEKALRSYECDAVIHFAGLKAVGESVAKPLEYYDNNVVGTVRLLEAMQATGVKTIVFS 122 A+E ALR Y+C +VIHFAGLKAVGESV KPL YYDNNV+GT +LL+AM G+KT+VFS Sbjct: 62 AAVEAALRQYDCQSVIHFAGLKAVGESVEKPLAYYDNNVIGTHKLLQAMSNCGIKTLVFS 121 Query: 123 SSATVYGVPQFLPYTEDHPLSSTSPYGRGKLMVEDILRDYHVAQPDSRIALLRYFNPVGA 182 SSATVYG PQFLP TE HPLS T+PYGR KL++ED+LRD + + RI +LRYFNPVGA Sbjct: 122 SSATVYGEPQFLPLTEQHPLSGTNPYGRTKLVIEDMLRDLYRSDSSWRIGILRYFNPVGA 181 Query: 183 HHSGLIGEDPQGVPNNLMPFVTQVAIGKRDRLQIWGGDYDTHDGTGVRDYIHVEDLAVGH 242 H SGLIGEDPQG+PNNLMPFV QVA+G+R+RL +WG DY T DGTGVRDYIHV DLA+GH Sbjct: 182 HESGLIGEDPQGIPNNLMPFVAQVAVGRRERLSVWGNDYPTPDGTGVRDYIHVVDLAIGH 241 Query: 243 VKALEHLRQPQCFAVNLGSGRGHSVLEVVKAFEQACGKSIPYEIGPRRAGDLPAYYADVT 302 +KAL L + +CF VNLG+G G SVL+V+KAFE A G+ IPYE+ PRRAGD+ + YAD Sbjct: 242 LKALACLSESRCFEVNLGTGTGCSVLDVIKAFESASGRPIPYELAPRRAGDVASCYADPA 301 Query: 303 LAKSLLGWKATRSLETMCADSWRWQQANPDGFR 335 A LL W+A R+LE MC D+WRWQ NP+GFR Sbjct: 302 FAAELLQWRAERNLEVMCVDAWRWQSNNPNGFR 334 >Q82WJ5.1 Q82WJ5_NITEU NAD dependent epimerase/dehydratase family EC=5.1.3.2 Length = 335 Score = 495 bits (1274), Expect = e-138, Method: Compositional matrix adjust. Identities = 229/334 (68%), Positives = 277/334 (82%) Query: 1 MNILVTGGAGYIGSHTCVELLKAGHQVVVFDNFCNSFPESVRRVEKITGKTLALVEGDIR 60 MN+LVTGGAGYIGSHTCVELL AG++VV+FDNFCNS PE++RR+E+IT K + +V GDIR Sbjct: 1 MNVLVTGGAGYIGSHTCVELLTAGYEVVIFDNFCNSHPEALRRIEQITSKKITIVTGDIR 60 Query: 61 DREALEKALRSYECDAVIHFAGLKAVGESVAKPLEYYDNNVVGTVRLLEAMQATGVKTIV 120 ++ A+EKAL+ Y C+AVIHFAGLKAVGESV KPLEYYDNNV+GT RLL AMQ GV T+V Sbjct: 61 NQVAIEKALKDYGCEAVIHFAGLKAVGESVEKPLEYYDNNVIGTHRLLAAMQNCGVYTLV 120 Query: 121 FSSSATVYGVPQFLPYTEDHPLSSTSPYGRGKLMVEDILRDYHVAQPDSRIALLRYFNPV 180 FSSSATVYG PQ LP TEDHPLS+T+PYGR KL++E++LRD + A P RIA+LRYFNPV Sbjct: 121 FSSSATVYGEPQRLPLTEDHPLSATNPYGRSKLIIEEMLRDVYRADPRFRIAILRYFNPV 180 Query: 181 GAHHSGLIGEDPQGVPNNLMPFVTQVAIGKRDRLQIWGGDYDTHDGTGVRDYIHVEDLAV 240 GAH SGLIGEDPQG+PNNLMPFV QVA+G+R+ L +WG DY THDGTGVRDYIHV DLA+ Sbjct: 181 GAHDSGLIGEDPQGIPNNLMPFVAQVAVGRREYLNVWGSDYPTHDGTGVRDYIHVVDLAL 240 Query: 241 GHVKALEHLRQPQCFAVNLGSGRGHSVLEVVKAFEQACGKSIPYEIGPRRAGDLPAYYAD 300 GH+ AL++L PQC A+NLG+G G+SVL+V+KAFE+A + I Y + RR+GD+ A YA+ Sbjct: 241 GHLGALDYLTVPQCMAINLGTGIGYSVLDVIKAFEEASSRQIDYRLASRRSGDVAACYAN 300 Query: 301 VTLAKSLLGWKATRSLETMCADSWRWQQANPDGF 334 LA+ LL WKA R L MC D WRWQ+ NP G+ Sbjct: 301 PALAEKLLRWKAQRDLAVMCRDHWRWQKNNPAGY 334