BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0032.p (438 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVQ3.1 D8IVQ3_HERSS Glutathione-regulated potassium-efflux sys... 555 e-156 F1VYB6.1 F1VYB6_9BURK Glutathione-regulated potassium-efflux sys... 536 e-150 Q1LHX8.1 Q1LHX8_RALME Potassium:proton antiporter 420 e-115 Q46WB0.1 Q46WB0_CUPPJ Potassium efflux system protein 418 e-115 Q21VE4.1 Q21VE4_RHOFD Potassium efflux system protein 415 e-114 >D8IVQ3.1 D8IVQ3_HERSS Glutathione-regulated potassium-efflux system transmembrane protein Length = 606 Score = 555 bits (1429), Expect = e-156, Method: Compositional matrix adjust. Identities = 309/370 (83%), Positives = 333/370 (90%) Query: 1 MEQTLLHPLIYLLAAVVAVPIAKKLGLGAVLGYLLAGIAIGPWGLGLISEVEDILHFSEF 60 M++ LL L+YLLAAV AVPIAK+LGLGAVLGYLLAGI IGPWGLGLI+EV+ IL FSEF Sbjct: 1 MDEQLLIALVYLLAAVAAVPIAKRLGLGAVLGYLLAGIVIGPWGLGLITEVKHILEFSEF 60 Query: 61 GVVLLLFLIGLELDPKRLWSLRRHIFGWGSAQVGLVSLGLFGAALAVGIDWRVALIGALG 120 GVVLLLFLIGLELDPKRLW+LRR IFGWGS QV VSL L AALA + WR+ LIGALG Sbjct: 61 GVVLLLFLIGLELDPKRLWALRRSIFGWGSIQVAAVSLALLAAALAASVPWRIGLIGALG 120 Query: 121 MSLSSTAIALATLGERKLTATPAGSAGFAILLFQDIAAIPMMAAVPLLGVAVAQGSGQGW 180 MSLSSTAIALATLGERKLTATPAGSA F+ILLFQDIAAIPMMAAVPLLGVA +QGSGQGW Sbjct: 121 MSLSSTAIALATLGERKLTATPAGSAAFSILLFQDIAAIPMMAAVPLLGVAASQGSGQGW 180 Query: 181 LHTLQVVAVIALLIFGGRYLIRPILRIIAKTDMREIFTAFSLLLVIATCLLMQSVGMSMA 240 LH QV VIALLIFGGR L+RPILRIIAKTDMREIFTAF+LLLVIATCLLMQSVGMSMA Sbjct: 181 LHAGQVALVIALLIFGGRVLMRPILRIIAKTDMREIFTAFALLLVIATCLLMQSVGMSMA 240 Query: 241 LGTFLAGVLLADSEYRHALESDLEPFKGLLLGLFFIAVGMSVDFGIFLEQPWLILGMVLG 300 LGTFLAGVLLADSEYRHALESDLEPFKGLLLGLFFIAVGMSVDFG+F QPW ILGMVLG Sbjct: 241 LGTFLAGVLLADSEYRHALESDLEPFKGLLLGLFFIAVGMSVDFGVFFAQPWRILGMVLG 300 Query: 301 FLVIKTAVLYGLAKCFRIPRDQQIFFSFLLSQGGEFAFVVFGAAATAQVLTPRISSILVV 360 FL IKT V++ L +CF IPR QQ+FF+FLLSQGGEFAF+VFGAA TA+VLTP SS+LVV Sbjct: 301 FLAIKTCVMWALGRCFGIPRGQQLFFAFLLSQGGEFAFIVFGAAVTAKVLTPETSSLLVV 360 Query: 361 VVALSMVITP 370 VVALSM++TP Sbjct: 361 VVALSMLVTP 370 >F1VYB6.1 F1VYB6_9BURK Glutathione-regulated potassium-efflux system protein KefC Length = 600 Score = 536 bits (1380), Expect = e-150, Method: Compositional matrix adjust. Identities = 304/395 (76%), Positives = 336/395 (85%), Gaps = 1/395 (0%) Query: 1 MEQTLL-HPLIYLLAAVVAVPIAKKLGLGAVLGYLLAGIAIGPWGLGLISEVEDILHFSE 59 ME +LL + LIYL+AAV+AVP+AKKLGLGAVLGYLLAGIAIGPWGLGLISEV+DILHFSE Sbjct: 1 MEHSLLFNALIYLVAAVIAVPVAKKLGLGAVLGYLLAGIAIGPWGLGLISEVDDILHFSE 60 Query: 60 FGVVLLLFLIGLELDPKRLWSLRRHIFGWGSAQVGLVSLGLFGAALAVGIDWRVALIGAL 119 FGVVLLLFLIGLELDPKRLWSLRR IFGWG AQVGLV+L LF +A+ +DW ALI AL Sbjct: 61 FGVVLLLFLIGLELDPKRLWSLRRPIFGWGGAQVGLVALALFLFGIALNVDWHTALIAAL 120 Query: 120 GMSLSSTAIALATLGERKLTATPAGSAGFAILLFQDIAAIPMMAAVPLLGVAVAQGSGQG 179 G+SLSSTAIALAT+GER L ATPAGSA FAILLFQD+AAIPM+A VPLLGV +G G Sbjct: 121 GLSLSSTAIALATIGERNLMATPAGSASFAILLFQDMAAIPMIAIVPLLGVNSGVTAGLG 180 Query: 180 WLHTLQVVAVIALLIFGGRYLIRPILRIIAKTDMREIFTAFSLLLVIATCLLMQSVGMSM 239 W+ ++V VI LI GGRYLIRPILRIIA T MREIFTAF+LLLVIA LLMQ VGMSM Sbjct: 181 WIDAAKIVGVIIALIIGGRYLIRPILRIIANTGMREIFTAFALLLVIAIGLLMQWVGMSM 240 Query: 240 ALGTFLAGVLLADSEYRHALESDLEPFKGLLLGLFFIAVGMSVDFGIFLEQPWLILGMVL 299 ALGTFLAGVLLADSEYRHALE+DLEPFKGLLLGLFFIAVGMSVDFGIF QPW++LG+V Sbjct: 241 ALGTFLAGVLLADSEYRHALETDLEPFKGLLLGLFFIAVGMSVDFGIFRAQPWVVLGLVA 300 Query: 300 GFLVIKTAVLYGLAKCFRIPRDQQIFFSFLLSQGGEFAFVVFGAAATAQVLTPRISSILV 359 FL IKT +LY L+K F IPR QQ F+FLLSQGGEFAFVVFGAAATA+VLTP I+S+LV Sbjct: 301 AFLSIKTLLLYLLSKSFGIPRGQQALFAFLLSQGGEFAFVVFGAAATARVLTPEIASLLV 360 Query: 360 VVVALSMVITPLLLLFHDRVLLPRPPPPPPVPCRP 394 VVVALSM+ TPLLL+F+DRVL PR P P Sbjct: 361 VVVALSMLATPLLLVFYDRVLAPRHRADKKRPDEP 395 >Q1LHX8.1 Q1LHX8_RALME Potassium:proton antiporter Length = 604 Score = 420 bits (1079), Expect = e-115, Method: Compositional matrix adjust. Identities = 222/383 (57%), Positives = 289/383 (75%), Gaps = 15/383 (3%) Query: 23 KKLGLGAVLGYLLAGIAIGPWGLGLISEVEDILHFSEFGVVLLLFLIGLELDPKRLWSLR 82 ++ GLGAVLGYLLAG AIGP+ L L++ VE ILHFSEFGVVL++F+IGLEL+P++L +LR Sbjct: 25 RRFGLGAVLGYLLAGAAIGPYALRLVTNVESILHFSEFGVVLMMFVIGLELEPRKLKNLR 84 Query: 83 RHIFGWGSAQVGLVSLGLFGAALAVGIDWRVALIGALGMSLSSTAIALATLGERKLTATP 142 + IFG+G+AQ+ +L + GAA +G W+VA++ LG++LSSTAIA ATL ER L TP Sbjct: 85 KTIFGYGTAQLAACALVVGGAAALLGASWQVAIVIGLGLALSSTAIAFATLAERNLMGTP 144 Query: 143 AGSAGFAILLFQDIAAIPMMAAVPLLGVAVAQGSGQG---WLHTLQVVAVIALLIFGGRY 199 AG+A F ILLFQDIAAIPM+A +PLL + A + G W + VAV+ +++ GGRY Sbjct: 145 AGAASFGILLFQDIAAIPMIALLPLLAIDAADIAPHGPPHWQTVARAVAVLGIVVVGGRY 204 Query: 200 LIRPILRIIAKTDMREIFTAFSLLLVIATCLLMQSVGMSMALGTFLAGVLLADSEYRHAL 259 L+RP LR IA+TDMRE+FTAF+LLLV+ L+M++VG+SMALGTF+AGVLLADSEY+HAL Sbjct: 205 LVRPALRFIARTDMREMFTAFALLLVVGIALMMEAVGVSMALGTFVAGVLLADSEYKHAL 264 Query: 260 ESDLEPFKGLLLGLFFIAVGMSVDFGIFLEQPWLILGMVLGFLVIKTAVLYGLAKCFRIP 319 E+D+EPFKGLLLGLFF+AVGMS+DFG+ + PW +LG+V GF+++KT VL LA F I Sbjct: 265 EADIEPFKGLLLGLFFMAVGMSIDFGVLAQAPWKVLGLVAGFVLVKTLVLAVLAPRFGIA 324 Query: 320 RDQQIFFSFLLSQGGEFAFVVFGAAATAQVLTPRISSILVVVVALSMVITPLLLLFHDRV 379 R Q + F L+SQGGEFAFVVF A +LT + ++LV++VALSMV TPLLLL D++ Sbjct: 325 RGQWLLFGLLISQGGEFAFVVFSVADNVGLLTEHMHALLVLIVALSMVATPLLLLVFDQL 384 Query: 380 LLPR------------PPPPPPV 390 + PR PP PV Sbjct: 385 IAPRLHILMRKPDDVIPPQHNPV 407 >Q46WB0.1 Q46WB0_CUPPJ Potassium efflux system protein Length = 602 Score = 418 bits (1075), Expect = e-115, Method: Compositional matrix adjust. Identities = 227/362 (62%), Positives = 283/362 (78%), Gaps = 1/362 (0%) Query: 23 KKLGLGAVLGYLLAGIAIGPWGLGLISEVEDILHFSEFGVVLLLFLIGLELDPKRLWSLR 82 ++ GLGAVLGYLLAG AIGP+ L +++ VE ILHFSEFGVVL++F+IGLEL+P++LW+LR Sbjct: 25 RRTGLGAVLGYLLAGAAIGPFALRMVTNVESILHFSEFGVVLMMFVIGLELEPRKLWALR 84 Query: 83 RHIFGWGSAQVGLVSLGLFGAALAVGIDWRVALIGALGMSLSSTAIALATLGERKLTATP 142 R IFG+G Q+ +L + A VG W VAL+ LG++LSSTAIALATLGER L TP Sbjct: 85 RSIFGYGGIQLAACALVIGILAALVGAPWPVALVAGLGLALSSTAIALATLGERNLFGTP 144 Query: 143 AGSAGFAILLFQDIAAIPMMAAVPLLGV-AVAQGSGQGWLHTLQVVAVIALLIFGGRYLI 201 AG A F ILLFQDIAAIPM+A +PLL + A SG GW + VAVIA ++FGGRYL+ Sbjct: 145 AGGASFGILLFQDIAAIPMIALLPLLAAESAADASGGGWQSAAKAVAVIAAVVFGGRYLV 204 Query: 202 RPILRIIAKTDMREIFTAFSLLLVIATCLLMQSVGMSMALGTFLAGVLLADSEYRHALES 261 RP LR IA+TDMRE+FTAF+LLLV+ L+M +VG+SMALGTF+AGVLLADSEYRHALE+ Sbjct: 205 RPALRFIARTDMREMFTAFALLLVVGIALMMDAVGLSMALGTFVAGVLLADSEYRHALEA 264 Query: 262 DLEPFKGLLLGLFFIAVGMSVDFGIFLEQPWLILGMVLGFLVIKTAVLYGLAKCFRIPRD 321 DLEPFKGLLLG+FF+AVGMS+DF + P +LG+V F+V KTAVL L + F I R Sbjct: 265 DLEPFKGLLLGMFFMAVGMSIDFAVLARAPGTVLGLVAVFVVAKTAVLMFLGRYFEIARG 324 Query: 322 QQIFFSFLLSQGGEFAFVVFGAAATAQVLTPRISSILVVVVALSMVITPLLLLFHDRVLL 381 Q++ F+ L+SQGGEFAFVVFG A TA +L ++LV++VALSMV TPLLLL +DR++ Sbjct: 325 QRLLFALLISQGGEFAFVVFGVAGTAGLLPRETEALLVLIVALSMVATPLLLLAYDRLVA 384 Query: 382 PR 383 PR Sbjct: 385 PR 386 >Q21VE4.1 Q21VE4_RHOFD Potassium efflux system protein Length = 628 Score = 415 bits (1066), Expect = e-114, Method: Compositional matrix adjust. Identities = 224/383 (58%), Positives = 296/383 (77%), Gaps = 4/383 (1%) Query: 5 LLHPLIYLLAAVVAVPIAKKLGLGAVLGYLLAGIAIGPWGLGLISEVEDILHFSEFGVVL 64 L++ IYL AAV+AVP++K LGLG+++GYL AGIAIGPWGLGL+++V++ILHF+EFGVVL Sbjct: 31 LINSFIYLSAAVIAVPLSKALGLGSIIGYLAAGIAIGPWGLGLVNDVQEILHFAEFGVVL 90 Query: 65 LLFLIGLELDPKRLWSLRRHIFGWGSAQVGLVSLGLFGAALAVGIDWRVALIGALGMSLS 124 +LFL+GLEL+PKRLWSLRR IFGWGSAQV ++ L A+ G+DWRVAL+ LG++LS Sbjct: 91 MLFLVGLELEPKRLWSLRRPIFGWGSAQVMGCAVVLTAVAMGFGVDWRVALVAGLGLALS 150 Query: 125 STAIALATLGERKLTATPAGSAGFAILLFQDIAAIPMMAAVPLLGVAVAQGS----GQGW 180 STAIAL +GER L T +G + FAILLFQD+AAIP++A +PLLG Q S Sbjct: 151 STAIALQVMGERNLLPTTSGQSSFAILLFQDVAAIPILALLPLLGAFSGQDSSLDTASKA 210 Query: 181 LHTLQVVAVIALLIFGGRYLIRPILRIIAKTDMREIFTAFSLLLVIATCLLMQSVGMSMA 240 L +L+++ VIA ++ GGR +RP+ R I+++ EIFTA +LLLV+ T LMQ VG+SMA Sbjct: 211 LESLKIIPVIAGIVLGGRLALRPVFRWISRSRTPEIFTAAALLLVVGTAALMQLVGLSMA 270 Query: 241 LGTFLAGVLLADSEYRHALESDLEPFKGLLLGLFFIAVGMSVDFGIFLEQPWLILGMVLG 300 LG FLAGVLLA+SEYR LE+D+EPFKGLLLGLFFIAVGMS+DFG+ + P L+ +V G Sbjct: 271 LGAFLAGVLLAESEYRRELETDIEPFKGLLLGLFFIAVGMSIDFGVLRDSPGLMAAVVAG 330 Query: 301 FLVIKTAVLYGLAKCFRIPRDQQIFFSFLLSQGGEFAFVVFGAAATAQVLTPRISSILVV 360 FL +K V+Y LA+ ++P +Q F+ LL+QGGEFAFVVF AAA A V + +S+L+ Sbjct: 331 FLAVKGVVIYALARMMKLPFQEQPVFTLLLAQGGEFAFVVFQAAAGANVFPAKTASLLIG 390 Query: 361 VVALSMVITPLLLLFHDRVLLPR 383 VA+SM+++PL+L+ DR+LLPR Sbjct: 391 AVAVSMLVSPLILVAIDRLLLPR 413