BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0746.p (289 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q127I2.1 Q127I2_POLSJ Major facilitator superfamily MFS_1 354 9e-96 C5CPJ7.1 C5CPJ7_VARPS Major facilitator superfamily MFS_1 327 2e-87 D8IVK5.1 D8IVK5_HERSS Oxalate/formate antiporter protein 302 5e-80 E6UWR1.1 E6UWR1_VARPD Major facilitator superfamily MFS_1 295 6e-78 A8TK39.1 A8TK39_9PROT Major facilitator superfamily MFS_1 279 4e-73 >Q127I2.1 Q127I2_POLSJ Major facilitator superfamily MFS_1 Length = 394 Score = 354 bits (908), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 178/241 (73%), Positives = 206/241 (85%), Gaps = 1/241 (0%) Query: 35 LITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVASMPYTLSMIGFGIGGMLMGKLADRF 94 +ITL LM +GASGMYVV VVLPAVQA+FGVAR AS+PYTL MIGFG+GG+LMG+LADRF Sbjct: 1 MITLALMTVGASGMYVVPVVLPAVQADFGVARADASLPYTLLMIGFGLGGVLMGRLADRF 60 Query: 95 GVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLLIGLCGSSATFSPLIADTSLWFVRR 154 GVM+PLL+GAV LGLG+ A MA NI +F LAHG L+GL GSSATF+PL+ADTSLWFVRR Sbjct: 61 GVMVPLLIGAVGLGLGYAAAAMASNIWMFMLAHGFLVGLLGSSATFAPLLADTSLWFVRR 120 Query: 155 RGIAVAVCASGNYLGGAIWPPIVQHFVDTVGWRQTYFGLGVVCFIVMGGLALLMRRRPPV 214 RGIAVAVCASGNY+GGAIWPP+VQHFV+ VGWRQTY GLG+ + M GLALLMR+RPP+ Sbjct: 121 RGIAVAVCASGNYVGGAIWPPVVQHFVEAVGWRQTYLGLGLFSVVTMAGLALLMRKRPPM 180 Query: 215 AVAA-AARNGVSLTSERPFGLPMGKAQLLLCVAGIACCVAMAMPQVHIVAYCGDLGYGAX 273 AVAA R+ + S PFGLP GKAQ+LLC+AG++CCVAMAMPQVHIV+YC DLGYGA Sbjct: 181 AVAAPVNRHFAASPSSLPFGLPPGKAQVLLCIAGVSCCVAMAMPQVHIVSYCTDLGYGAA 240 Query: 274 H 274 Sbjct: 241 R 241 >C5CPJ7.1 C5CPJ7_VARPS Major facilitator superfamily MFS_1 Length = 417 Score = 327 bits (837), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 164/260 (63%), Positives = 200/260 (76%), Gaps = 4/260 (1%) Query: 16 KKDPGNNFGADSSYAVVRLLITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVASMPYTL 75 K + ADS YA++RL +TL++M +G+SGMYVV+V+LPAVQAEFG+AR AS+PYTL Sbjct: 2 KTFETSAHAADSRYAMLRLGLTLLVMTVGSSGMYVVSVMLPAVQAEFGIARADASLPYTL 61 Query: 76 SMIGFGIGGMLMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLLIGLCG 135 M+GFG+GG+LMG+LADRFGVM PLL+GA+ LG+G++ GMA I+ FTLA +L+GL G Sbjct: 62 LMLGFGVGGVLMGRLADRFGVMWPLLIGALSLGVGYVACGMADGIVSFTLAQAVLVGLLG 121 Query: 136 SSATFSPLIADTSLWFVRRRGIAVAVCASGNYLGGAIWPPIVQHFVDTVGWRQTYFGLGV 195 S+A F+PL+ADTSLWFV+RRGIAVAVCASGNY+ GAIWPPI QHF++TVGWRQTY G+G+ Sbjct: 122 SAAAFAPLVADTSLWFVKRRGIAVAVCASGNYVAGAIWPPIAQHFIETVGWRQTYIGMGL 181 Query: 196 VCFIVMGGLALLM----RRRPPVAVAAAARNGVSLTSERPFGLPMGKAQLLLCVAGIACC 251 C + M LAL + A G RPFG MG AQ LLCVAG+ACC Sbjct: 182 FCGLAMAALALFFRARPPAVAAAPASHAGHAGRRRDMTRPFGFSMGTAQGLLCVAGVACC 241 Query: 252 VAMAMPQVHIVAYCGDLGYG 271 VAMAMPQVHIVAYCGDLGYG Sbjct: 242 VAMAMPQVHIVAYCGDLGYG 261 >D8IVK5.1 D8IVK5_HERSS Oxalate/formate antiporter protein Length = 416 Score = 302 bits (773), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 175/248 (70%), Positives = 203/248 (81%), Gaps = 5/248 (2%) Query: 26 DSSYAVVRLLITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVASMPYTLSMIGFGIGGM 85 DS YAV+RL IT+VLMV+GASGMYV+AVVLP VQA + V RG+ASMPYTL+M+G G+GG+ Sbjct: 18 DSPYAVMRLCITMVLMVVGASGMYVIAVVLPYVQAHYYVDRGLASMPYTLTMLGVGVGGL 77 Query: 86 LMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLLIGLCGSSATFSPLIA 145 LMG++ADR G+ PL +G +CLG GFI A AP+I F H L IGL G+SATFSPL+A Sbjct: 78 LMGRMADRAGITRPLFLGGLCLGGGFIAASYAPDIWTFMAVHCLFIGLLGTSATFSPLVA 137 Query: 146 DTSLWFVRRRGIAVAVCASGNYLGGAIWPPIVQHFVDTVGWRQTYFGLGVVCFIVMGGLA 205 DTSLWF +RRGIAVAVCASGNYLGGAIWPPIVQHFVD+VGW+QTY G+G+ C ++M LA Sbjct: 138 DTSLWFRKRRGIAVAVCASGNYLGGAIWPPIVQHFVDSVGWQQTYIGMGIACSLIMCSLA 197 Query: 206 LLMRRRPPV--AVAAAARNGVSLTSERPFGLPMGKAQLLLCVAGIACCVAMAMPQVHIVA 263 LLMR RPP + AA+AR G RPFGL G AQLLLCVAG+ACCVAMAMPQVHIVA Sbjct: 198 LLMRARPPAQDSSAASARPG---GGPRPFGLAPGSAQLLLCVAGVACCVAMAMPQVHIVA 254 Query: 264 YCGDLGYG 271 YCGDLGYG Sbjct: 255 YCGDLGYG 262 >E6UWR1.1 E6UWR1_VARPD Major facilitator superfamily MFS_1 Length = 422 Score = 295 bits (755), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 169/260 (65%), Positives = 201/260 (77%), Gaps = 4/260 (1%) Query: 16 KKDPGNNFGADSSYAVVRLLITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVASMPYTL 75 K ADS YA++RL +TL++M +G+SGMYVV+V+LPAVQAEFG+ R AS+PYT Sbjct: 3 KTSETTAHAADSRYAMLRLALTLLIMTVGSSGMYVVSVMLPAVQAEFGIDRADASLPYTW 62 Query: 76 SMIGFGIGGMLMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLLIGLCG 135 M+GFG GG+LMGKLADRFGVM PLL+G+V LG G+I G++ I+ FT+A LL+GL G Sbjct: 63 LMLGFGFGGVLMGKLADRFGVMWPLLLGSVFLGAGYIATGLSGGIVSFTIAQALLVGLLG 122 Query: 136 SSATFSPLIADTSLWFVRRRGIAVAVCASGNYLGGAIWPPIVQHFVDTVGWRQTYFGLGV 195 SSA F+PL+ADTSLWFV+RRGIAVAVCASGNY+ GAIWPPI QHF++TVGWRQTY G+G+ Sbjct: 123 SSAAFAPLVADTSLWFVKRRGIAVAVCASGNYVAGAIWPPIAQHFIETVGWRQTYIGMGI 182 Query: 196 VCFIVMGGLALLMRRRPPVAVAAAARNGVSLTS----ERPFGLPMGKAQLLLCVAGIACC 251 C I M LAL R RPP AA N + T+ RPFGL M AQ LLCVA +ACC Sbjct: 183 FCGIAMALLALFFRARPPAVAAAPVGNASNATAPRDMTRPFGLSMTTAQGLLCVAAVACC 242 Query: 252 VAMAMPQVHIVAYCGDLGYG 271 VAMAMPQVHIVAYCGDLGYG Sbjct: 243 VAMAMPQVHIVAYCGDLGYG 262 >A8TK39.1 A8TK39_9PROT Major facilitator superfamily MFS_1 Length = 419 Score = 279 bits (713), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 141/270 (52%), Positives = 187/270 (69%), Gaps = 11/270 (4%) Query: 11 FKDDPKKDPGNNFGADSSYAVVRLLITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVAS 70 D + P ADS YA RL ++L++ +IG G++ V V LPAV+AEFGVARG AS Sbjct: 1 MTTDSRAAPVMAGEADSPYAWYRLAMSLLISMIGGVGLWSVVVTLPAVEAEFGVARGDAS 60 Query: 71 MPYTLSMIGFGIGGMLMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLL 130 +PYT +MIGF IGG++MG+LADRFG+++PL G + L LG+ A + ++ +TLAHGLL Sbjct: 61 LPYTATMIGFAIGGIMMGRLADRFGILVPLRCGTIALALGYAAASQSTSLWQYTLAHGLL 120 Query: 131 IGLCGSSATFSPLIADTSLWFVRRRGIAVAVCASGNYLGGAIWPPIVQHFVDTVGWRQTY 190 +GL GSS+TF P+I+D SLWFVRRRGIAVA+ ASG+Y+ G +WPPI+QH ++T+GWR T+ Sbjct: 121 VGLLGSSSTFGPIISDVSLWFVRRRGIAVAIGASGSYMAGTVWPPIIQHLIETIGWRDTH 180 Query: 191 FGLGVVCFIVMGGLALLMRRRPPVAVA-----AAARNGVSLTSE-RPFGLPMGKAQLLLC 244 + CF+ + L+ +RRRPP +A A R G S+ S P L Q LL Sbjct: 181 LVVAAFCFVTLIPLSAALRRRPPSTLASVPPSAEPRGGGSMASTMSPAAL-----QTLLL 235 Query: 245 VAGIACCVAMAMPQVHIVAYCGDLGYGAXH 274 +AG++CCVAMAMPQVHIVAYC DLG G Sbjct: 236 IAGLSCCVAMAMPQVHIVAYCADLGIGTAR 265