BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0616.p         (188 letters)

Database: pfamseq 
           15,929,002 sequences; 5,169,768,107 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D8IP91.1 D8IP91_HERSS Pseudouridine synthase EC=5.4.99.-              298   2e-79
A6T110.1 A6T110_JANMA Pseudouridylate synthase family protein EC...   285   3e-75
A4G7U1.1 A4G7U1_HERAR Pseudouridine synthase EC=5.4.99.-              281   5e-74
F1W1C3.1 F1W1C3_9BURK Putative Pseudouridylate synthase               261   2e-68
Q1GZD2.1 Q1GZD2_METFK Pseudouridine synthase EC=5.4.99.-              228   3e-58

>D8IP91.1 D8IP91_HERSS Pseudouridine synthase EC=5.4.99.-
          Length = 188

 Score =  298 bits (764), Expect = 2e-79,   Method: Compositional matrix adjust.
 Identities = 137/188 (72%), Positives = 162/188 (86%)

Query: 1   MPLILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAI 60
           MPLIL NKP+QVM QFSA  +R+TLADY+DIP++YPAGRLDADSEGL+LLTDDG+LQHAI
Sbjct: 1   MPLILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAI 60

Query: 61  SHPKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIR 120
           +HP+RK PK YL QVEG P   +L++LR PLDLGDFVT+ S+ R +QEP W+WPRNPPIR
Sbjct: 61  AHPRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIQEPGWMWPRNPPIR 120

Query: 121 ERKNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTVD 180
           +R+N PTSW+ + ISEGKNRQVRRMTAAVGLPTLRLVRIAIGPF+LAT P++PGEW+ VD
Sbjct: 121 QRQNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREVD 180

Query: 181 PQEFHRDN 188
           P E  R  
Sbjct: 181 PLELERQG 188


>A6T110.1 A6T110_JANMA Pseudouridylate synthase family protein EC=4.2.1.70
          Length = 211

 Score =  285 bits (728), Expect = 3e-75,   Method: Compositional matrix adjust.
 Identities = 134/184 (72%), Positives = 152/184 (82%)

Query: 1   MPLILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAI 60
           MPLILFNKP+Q MCQFS    R++LAD++DIP+IYPAGRLDADSEGL+LL DDG+LQHAI
Sbjct: 25  MPLILFNKPFQTMCQFSPHPTRKSLADHIDIPNIYPAGRLDADSEGLLLLNDDGKLQHAI 84

Query: 61  SHPKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIR 120
           SHP RK  K YLVQVEG PDA++L RLR PLDLGDFVT++ EV+ V EP WLWPRNPPIR
Sbjct: 85  SHPDRKHTKTYLVQVEGVPDADALARLRAPLDLGDFVTQECEVKRVAEPDWLWPRNPPIR 144

Query: 121 ERKNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTVD 180
           ER N PTSWL I +SEGKNRQVRRMT AVG PTLRLVRIAIGP +L + PL PGEW+ + 
Sbjct: 145 ERANAPTSWLAITLSEGKNRQVRRMTGAVGYPTLRLVRIAIGPVSLQSHPLWPGEWREIS 204

Query: 181 PQEF 184
             E 
Sbjct: 205 VAEL 208


>A4G7U1.1 A4G7U1_HERAR Pseudouridine synthase EC=5.4.99.-
          Length = 186

 Score =  281 bits (718), Expect = 5e-74,   Method: Compositional matrix adjust.
 Identities = 133/184 (72%), Positives = 149/184 (80%)

Query: 1   MPLILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAI 60
           M LILFNKP+QVMCQFS    R +LADYLDIPDIYPAGRLDADSEGL+LLTDDG+LQHAI
Sbjct: 1   MSLILFNKPFQVMCQFSPHPTRASLADYLDIPDIYPAGRLDADSEGLLLLTDDGKLQHAI 60

Query: 61  SHPKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIR 120
           SHP  KQ K YL QVEG P   +L RLR PL+LGDF+T+  EV+ VQEP WLWPRNPPIR
Sbjct: 61  SHPDHKQTKTYLAQVEGIPHTEALARLRAPLNLGDFITQGCEVKRVQEPDWLWPRNPPIR 120

Query: 121 ERKNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTVD 180
           ER   PTSWL I ++EGKNRQVRRMT AVGLPTLRL+RIAIGP +L + PLLPG+W+ V 
Sbjct: 121 ERAQVPTSWLAITLAEGKNRQVRRMTGAVGLPTLRLIRIAIGPISLQSHPLLPGQWREVS 180

Query: 181 PQEF 184
             E 
Sbjct: 181 AAEL 184


>F1W1C3.1 F1W1C3_9BURK Putative Pseudouridylate synthase
          Length = 189

 Score =  261 bits (668), Expect = 2e-68,   Method: Compositional matrix adjust.
 Identities = 127/184 (69%), Positives = 144/184 (78%)

Query: 1   MPLILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAI 60
           M LILFNKPY V+CQFS Q  R TLAD+L IPDIYPAGRLDADSEGLMLLTDDG LQH I
Sbjct: 1   MALILFNKPYLVLCQFSPQAGRRTLADHLAIPDIYPAGRLDADSEGLMLLTDDGRLQHDI 60

Query: 61  SHPKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIR 120
           S P  KQPK YLVQ+EG PD  +L  LR  + LGDF ++ ++V  V  PAWLWPRNPPIR
Sbjct: 61  SDPTHKQPKAYLVQIEGIPDPVALNTLRTGVFLGDFTSKAAKVIEVATPAWLWPRNPPIR 120

Query: 121 ERKNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTVD 180
           +R   PT WL + I+EGKNRQVRRMTAAVGLPTLRLVR+AIGP++L + PLLPGE + VD
Sbjct: 121 QRAVTPTRWLLLTITEGKNRQVRRMTAAVGLPTLRLVRVAIGPYSLESHPLLPGESRVVD 180

Query: 181 PQEF 184
             E 
Sbjct: 181 AAEL 184


>Q1GZD2.1 Q1GZD2_METFK Pseudouridine synthase EC=5.4.99.-
          Length = 176

 Score =  228 bits (581), Expect = 3e-58,   Method: Compositional matrix adjust.
 Identities = 109/177 (61%), Positives = 136/177 (76%), Gaps = 2/177 (1%)

Query: 3   LILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAISH 62
           LILFNKPY V+CQFS  +  +TL DY+ +P +Y AGRLD DSEGL++LTDDG LQH ISH
Sbjct: 2   LILFNKPYGVICQFSPHEKHKTLKDYIAVPGVYAAGRLDTDSEGLLILTDDGRLQHRISH 61

Query: 63  PKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIRER 122
           P+ K+ K Y VQVEG P   +LE LR+ +DLGDFVT+ ++VR ++EPA LWPR+PPIRER
Sbjct: 62  PRHKEFKTYWVQVEGDPSDEALEPLRHGMDLGDFVTQPAKVRRIEEPAGLWPRHPPIRER 121

Query: 123 KNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTV 179
           K  PT+WL + I+EGKNRQVRRMTA  G PTLRLVR A+G   L  + + PGEW+ +
Sbjct: 122 KAIPTAWLEVIIAEGKNRQVRRMTAKAGFPTLRLVRYAVGQHTL--EGIAPGEWRQL 176