BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0608.p (459 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D5NIM7.1 D5NIM7_9BURK Penicillin-binding protein, 1A family 458 e-127 Q13Y35.1 Q13Y35_BURXL Putative penicillin-binding (Peptidoglycan... 456 e-126 B2T534.1 B2T534_BURPP Penicillin-binding protein, 1A family 455 e-126 B1G775.1 B1G775_9BURK Penicillin-binding protein, 1A family 453 e-125 D5W8M9.1 D5W8M9_BURSC Penicillin-binding protein, 1A family 452 e-125 >D5NIM7.1 D5NIM7_9BURK Penicillin-binding protein, 1A family Length = 833 Score = 458 bits (1178), Expect = e-127, Method: Compositional matrix adjust. Identities = 225/389 (57%), Positives = 286/389 (73%), Gaps = 38/389 (9%) Query: 17 LNPNIAKFLAFSVLGLAVIGALIIAYALIFINPRLPSLDVITDYRPKIPLRIYSADNVLL 76 + IA + A + +AV+GALII YAL+ + P+LPSLD +TDYRPK+PLR+Y+AD+VL+ Sbjct: 41 IGATIAIWFAGLIATVAVVGALIIGYALVVMGPQLPSLDALTDYRPKVPLRVYTADHVLI 100 Query: 77 GEFGEEKRSLVKLDDIPANMKNAVLAIEDNRFYQHGGIDYIGIARAIATDVVRGHASQGA 136 GEFGEE+RSLV+ DIP MK AVLAIED RFY+HGG+D+IGI RA +D+ G ASQGA Sbjct: 101 GEFGEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGASQGA 160 Query: 137 STITMQVARNVFLTKEKTVSRKLYEVLLANKIEAALSKDQILE----------------- 179 STITMQVARN FL+ EKT +RK+YE+LLA KIE AL+KDQILE Sbjct: 161 STITMQVARNFFLSSEKTYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAA 220 Query: 180 ---------------------XPRPGAPSAYNPIVNPKRAHIRQQYILQRMLDLDYITQK 218 P APSAYNP+VNPKRA IRQ+YIL+RML+L YI+Q+ Sbjct: 221 AARVYFGKDLKDITLAESAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQE 280 Query: 219 EYDAAVKEDIQVRAPGNQYNVHAEYVNEMVRQMVYAQYKEDTYTHGITVTTTINAADQKA 278 +YD AVKE+I + PGN+Y+VHAEY+ EMVRQM+YAQYK++TYT G+ VTTTI++ADQ A Sbjct: 281 QYDQAVKEEIHTKNPGNEYSVHAEYIAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQDA 340 Query: 279 AYDAVRKGVMDYDRRHGYRGPEETIDLPSKDEDRAQAIDDAMDDYPDNDDILAAVVLSAD 338 AY AVRKGVMDY+RRHGYRGPE + LP+ +DR Q IDDA+ D+PDN +I+AAVV A Sbjct: 341 AYRAVRKGVMDYERRHGYRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVTDAS 400 Query: 339 PKQIQAVIRSGDKITLSGDTLKFVAXKIT 367 PKQ++A + G ++ +SGD L+FVA ++ Sbjct: 401 PKQVKAQLVDGTQVAISGDGLRFVAGALS 429 >Q13Y35.1 Q13Y35_BURXL Putative penicillin-binding (Peptidoglycan synthetase) transmembrane protein, mrcA EC=2.4.2.- Length = 836 Score = 456 bits (1172), Expect = e-126, Method: Compositional matrix adjust. Identities = 224/386 (58%), Positives = 284/386 (73%), Gaps = 38/386 (9%) Query: 20 NIAKFLAFSVLGLAVIGALIIAYALIFINPRLPSLDVITDYRPKIPLRIYSADNVLLGEF 79 IA + A + +AV+ ALII YAL+ + P+LPSLD +TDYRPK+PLR+Y+AD+VL+GEF Sbjct: 47 TIAIWFAGLIATIAVVSALIIGYALVVMGPQLPSLDALTDYRPKVPLRVYTADHVLIGEF 106 Query: 80 GEEKRSLVKLDDIPANMKNAVLAIEDNRFYQHGGIDYIGIARAIATDVVRGHASQGASTI 139 GEE+RSLV+ DIP MK AVLAIED RFY+HGG+D+IGI RA +D+ G ASQGASTI Sbjct: 107 GEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGASQGASTI 166 Query: 140 TMQVARNVFLTKEKTVSRKLYEVLLANKIEAALSKDQILE-------------------- 179 TMQVARN FL+ EKT +RK+YE+LLA KIE AL+KDQILE Sbjct: 167 TMQVARNFFLSSEKTYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAAR 226 Query: 180 ------------------XPRPGAPSAYNPIVNPKRAHIRQQYILQRMLDLDYITQKEYD 221 P APSAYNP+VNPKRA IRQ+YIL+RML+L YI+Q++YD Sbjct: 227 VYFGKDLKDITLAESAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQEQYD 286 Query: 222 AAVKEDIQVRAPGNQYNVHAEYVNEMVRQMVYAQYKEDTYTHGITVTTTINAADQKAAYD 281 AVKE+I + PGN+Y+VHAEY+ EMVRQM+YAQYK++TYT G+ VTTTI++ADQ AAY Sbjct: 287 QAVKEEIHTKNPGNEYSVHAEYIAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQDAAYR 346 Query: 282 AVRKGVMDYDRRHGYRGPEETIDLPSKDEDRAQAIDDAMDDYPDNDDILAAVVLSADPKQ 341 AVRKGVMDY+RRHGYRGPE + LP+ +DR Q IDDA+ D+PDN +I+AAVV A PKQ Sbjct: 347 AVRKGVMDYERRHGYRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVTDASPKQ 406 Query: 342 IQAVIRSGDKITLSGDTLKFVAXKIT 367 ++A + G ++ +SGD L+FVA ++ Sbjct: 407 VKAQLVDGTQVAISGDGLRFVAGALS 432 >B2T534.1 B2T534_BURPP Penicillin-binding protein, 1A family Length = 833 Score = 455 bits (1171), Expect = e-126, Method: Compositional matrix adjust. Identities = 223/389 (57%), Positives = 284/389 (73%), Gaps = 38/389 (9%) Query: 17 LNPNIAKFLAFSVLGLAVIGALIIAYALIFINPRLPSLDVITDYRPKIPLRIYSADNVLL 76 L + + A + +AV+GALI+ YAL+ + P+LPSLD +TDYRPK+PLR+Y+AD+VL+ Sbjct: 41 LGTTLVIWFASLLATIAVVGALIVGYALVVMGPQLPSLDALTDYRPKVPLRVYTADHVLI 100 Query: 77 GEFGEEKRSLVKLDDIPANMKNAVLAIEDNRFYQHGGIDYIGIARAIATDVVRGHASQGA 136 GEFGEE+RSLV+ DIP MK AVLAIED RFY+HGG+D+IGI RA +D+ G ASQGA Sbjct: 101 GEFGEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGASQGA 160 Query: 137 STITMQVARNVFLTKEKTVSRKLYEVLLANKIEAALSKDQILE----------------- 179 STITMQVARN FL+ EKT +RK+YE+LLA KIE AL+KDQILE Sbjct: 161 STITMQVARNFFLSSEKTYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAA 220 Query: 180 ---------------------XPRPGAPSAYNPIVNPKRAHIRQQYILQRMLDLDYITQK 218 P APSAYNP+VNPKRA IRQ+YIL+RML+L YI+Q Sbjct: 221 AARVYFGKDLKDITLAESAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELKYISQD 280 Query: 219 EYDAAVKEDIQVRAPGNQYNVHAEYVNEMVRQMVYAQYKEDTYTHGITVTTTINAADQKA 278 +YD AVKE+I + PGN+Y+VHAEY+ EMVRQM+YAQYK++TYT G+ VTTTI++ADQ A Sbjct: 281 QYDQAVKEEIHTKNPGNEYSVHAEYIAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQDA 340 Query: 279 AYDAVRKGVMDYDRRHGYRGPEETIDLPSKDEDRAQAIDDAMDDYPDNDDILAAVVLSAD 338 AY AVRKGVMDY+RRHGYRGPE + LP+ +DR Q IDDA+ D+PDN +I+AAVV A Sbjct: 341 AYRAVRKGVMDYERRHGYRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVTEAA 400 Query: 339 PKQIQAVIRSGDKITLSGDTLKFVAXKIT 367 PKQ++A + G ++T+SGD L+F A ++ Sbjct: 401 PKQVKAQLVDGTQVTISGDGLRFAAGALS 429 >B1G775.1 B1G775_9BURK Penicillin-binding protein, 1A family Length = 833 Score = 453 bits (1165), Expect = e-125, Method: Compositional matrix adjust. Identities = 221/382 (57%), Positives = 283/382 (74%), Gaps = 39/382 (10%) Query: 24 FLAFSVLGLAVIGALIIAYALIFINPRLPSLDVITDYRPKIPLRIYSADNVLLGEFGEEK 83 F +F+ + +AV+GALI+ YAL+ + P LPSLD +TDYRPK+PLR+Y+AD+VL+GEFGEE+ Sbjct: 49 FASFAAI-VAVVGALIVGYALVVMGPNLPSLDALTDYRPKVPLRVYTADHVLIGEFGEER 107 Query: 84 RSLVKLDDIPANMKNAVLAIEDNRFYQHGGIDYIGIARAIATDVVRGHASQGASTITMQV 143 RSLV+ DIP MK AVLAIED RFY+HGG+D++GI RA D+ G ASQGASTITMQV Sbjct: 108 RSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFLGILRAGFADLAHGGASQGASTITMQV 167 Query: 144 ARNVFLTKEKTVSRKLYEVLLANKIEAALSKDQILE------------------------ 179 ARN FL+ EKT +RK+YE+LLA KIE AL+KDQILE Sbjct: 168 ARNFFLSSEKTYTRKVYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAARVYFG 227 Query: 180 --------------XPRPGAPSAYNPIVNPKRAHIRQQYILQRMLDLDYITQKEYDAAVK 225 P APSAYNP+VNPKRA IRQ+YIL+RM +L YI+Q++YD AVK Sbjct: 228 KDLKDITLAQAAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMFELRYISQEQYDQAVK 287 Query: 226 EDIQVRAPGNQYNVHAEYVNEMVRQMVYAQYKEDTYTHGITVTTTINAADQKAAYDAVRK 285 E+I R PGN+Y+VHAEY+ EMVRQM+YAQYK++TYT G+ VTTTI++ADQ AAY AVRK Sbjct: 288 EEIHTRNPGNEYSVHAEYIAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQDAAYRAVRK 347 Query: 286 GVMDYDRRHGYRGPEETIDLPSKDEDRAQAIDDAMDDYPDNDDILAAVVLSADPKQIQAV 345 GVMDY+RRHGYRGPE + LP+ +DR Q IDDA+ D+PDN +++AAVV A PKQ++A Sbjct: 348 GVMDYERRHGYRGPEGFVQLPAAGDDRDQTIDDALTDHPDNGELVAAVVTDASPKQVKAQ 407 Query: 346 IRSGDKITLSGDTLKFVAXKIT 367 + G ++T+SG+ L+FVA ++ Sbjct: 408 LVDGTQVTMSGEGLRFVANALS 429 >D5W8M9.1 D5W8M9_BURSC Penicillin-binding protein, 1A family Length = 846 Score = 452 bits (1162), Expect = e-125, Method: Compositional matrix adjust. Identities = 226/390 (57%), Positives = 283/390 (72%), Gaps = 42/390 (10%) Query: 20 NIAKFLAFSVLGL----AVIGALIIAYALIFINPRLPSLDVITDYRPKIPLRIYSADNVL 75 +I L +GL AVIGALI+ YAL+ + P+LPSLD +TDYRPK+PLR+Y+AD+VL Sbjct: 53 SIGASLVLWFIGLIATVAVIGALIVGYALVVMGPQLPSLDALTDYRPKVPLRVYTADHVL 112 Query: 76 LGEFGEEKRSLVKLDDIPANMKNAVLAIEDNRFYQHGGIDYIGIARAIATDVVRGHASQG 135 +GEFGEE+RSLV+ DIP MK AVLAIED RFY+HGG+D++GI RA D+ G ASQG Sbjct: 113 IGEFGEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFLGILRAGFADLAHGGASQG 172 Query: 136 ASTITMQVARNVFLTKEKTVSRKLYEVLLANKIEAALSKDQILE---------------- 179 ASTITMQVARN FL+ EKT +RK+YE+LLA KIE AL+KDQILE Sbjct: 173 ASTITMQVARNFFLSSEKTYTRKVYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFA 232 Query: 180 ----------------------XPRPGAPSAYNPIVNPKRAHIRQQYILQRMLDLDYITQ 217 P APSAYNP+VNPKRA IRQ+YIL+RML+L YITQ Sbjct: 233 AAARVYFGKDLKDISLAQAAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYITQ 292 Query: 218 KEYDAAVKEDIQVRAPGNQYNVHAEYVNEMVRQMVYAQYKEDTYTHGITVTTTINAADQK 277 ++YD AVKE+I + PGN+Y+VHAEYV EMVRQM+YAQYK++TYT G+ VTTTI++ADQ Sbjct: 293 QQYDQAVKEEIHTKNPGNEYSVHAEYVAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQD 352 Query: 278 AAYDAVRKGVMDYDRRHGYRGPEETIDLPSKDEDRAQAIDDAMDDYPDNDDILAAVVLSA 337 AAY AVRKGVMDY+RRHGYRGPE + LP +DR Q IDDA+ D+PDN +I+A VV +A Sbjct: 353 AAYRAVRKGVMDYERRHGYRGPEGFVQLPEAGDDRDQTIDDALTDHPDNGEIIAGVVTAA 412 Query: 338 DPKQIQAVIRSGDKITLSGDTLKFVAXKIT 367 + KQ+ A + G ++T+SGD L+FVA ++ Sbjct: 413 NAKQVVAQLVDGTQVTVSGDGLRFVAAALS 442