BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0573.p (441 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IUG8.1 D8IUG8_HERSS Permease of the major facilitator superfam... 711 0.0 D4X427.1 D4X427_9BURK Major facilitator family transporter 656 0.0 A9BVT8.1 A9BVT8_DELAS Major facilitator superfamily MFS_1 655 0.0 B1G020.1 B1G020_9BURK Major facilitator superfamily MFS_1 648 0.0 E8YT54.1 E8YT54_9BURK Major facilitator superfamily MFS_1 647 0.0 >D8IUG8.1 D8IUG8_HERSS Permease of the major facilitator superfamily protein Length = 437 Score = 711 bits (1836), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/441 (80%), Positives = 389/441 (88%), Gaps = 4/441 (0%) Query: 1 MTASTNIGAAPAVNTSANEQEQNRVYAKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSV 60 MT ++ G V N++ ++ +Y KVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMS Sbjct: 1 MTTASTTG----VGLDVNDKSKDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQ 56 Query: 61 DLGFSETVFGLGAGVFFLGYFLFEVPSNILMHKVGARVWIARIMITWGILSAAFMYVETP 120 DLGFSETVFGLGAG+FF+GYFLFEVPSNILMHKVGAR+WIARIMITWGILSAAFM+V+ Sbjct: 57 DLGFSETVFGLGAGLFFIGYFLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNA 116 Query: 121 MQFYVLRFLLGLAEAGFYPGIILYLTYWYPSHRRAKVIAVFMSGIPVAGILGNPLSGWIM 180 QFY+LRFLLGLAEAGFYPGIILYLTYW+PSHRRAKVIAVFMSGIPVAGILGNPLSGWIM Sbjct: 117 TQFYILRFLLGLAEAGFYPGIILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIM 176 Query: 181 DAFHGTTGMHGWQWMFVIEAVPAVLIGLATLAYLDNGIAKAKWLSAGEKKLLEDEIAADQ 240 DAFH G+ GWQWMF+IEA+PAVLIG+AT+ YLDN + AKWL+ EK L+ +I D Sbjct: 177 DAFHQNGGLEGWQWMFLIEAIPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDA 236 Query: 241 KGKESVHSFADIVSDKRVWLMCLIYFCFVMGQYGLTLWMPTLVKATGVTGNLHIGLLSAI 300 KGKES H F IV D RVWLMCLIYF FVMGQYGLTLWMPTLVKATGV GNL IGLLSAI Sbjct: 237 KGKESKHGFGAIVKDARVWLMCLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAI 296 Query: 301 PFGCAIIAMNLIGRSADARRERRWHLIVPALMGAVGFVGAALFADNTAISIAALSLAAAG 360 PFGCAIIAMNLIGRSAD RERRWHL++PALMG VGFVGAALFADNTA+SIA+LSLAAAG Sbjct: 297 PFGCAIIAMNLIGRSADRMRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAG 356 Query: 361 VLTCAPLFWSLPTSFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHSGATGMYML 420 VLTCAPLFWSLPT+FLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTH+ ATGMYML Sbjct: 357 VLTCAPLFWSLPTAFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYML 416 Query: 421 AIMLVIGSAAVLKTSPKLVNK 441 A+MLV+GS A L T P +VNK Sbjct: 417 AVMLVVGSIATLATKPGMVNK 437 >D4X427.1 D4X427_9BURK Major facilitator family transporter Length = 445 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/442 (73%), Positives = 369/442 (83%), Gaps = 3/442 (0%) Query: 1 MTASTNIGAAPAVNTSANEQEQNRVYAKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSV 60 +T+ N+ A A +E R YAKVFWR++PFLMLCYVIAYLDRVNVGFAKLQMS Sbjct: 6 LTSGANVAAHAA--PQPESRETARAYAKVFWRLVPFLMLCYVIAYLDRVNVGFAKLQMSQ 63 Query: 61 DLGFSETVFGLGAGVFFLGYFLFEVPSNILMHKVGARVWIARIMITWGILSAAFMYVETP 120 DLGFSETVFGLGAGVFF+GYFLFEVPSN+LMH++GAR+WIARIMITWGILS FM+VETP Sbjct: 64 DLGFSETVFGLGAGVFFIGYFLFEVPSNLLMHRLGARIWIARIMITWGILSGMFMFVETP 123 Query: 121 MQFYVLRFLLGLAEAGFYPGIILYLTYWYPSHRRAKVIAVFMSGIPVAGILGNPLSGWIM 180 FY+LRFLLGLAEAGFYPG+ILYLTYWYP+HRRAK+IA+FMS IPVAGI GNPLSGWIM Sbjct: 124 TGFYILRFLLGLAEAGFYPGVILYLTYWYPAHRRAKIIALFMSAIPVAGIFGNPLSGWIM 183 Query: 181 DAFHGTTGMHGWQWMFVIEAVPAVLIGLATLAYLDNGIAKAKWLSAGEKKLLEDEIAADQ 240 +AFHGT G+ GWQWMF+IEA+PA+LIG+ T+ YLDNGIA AKWL+ EK+LL EI DQ Sbjct: 184 EAFHGTHGLQGWQWMFLIEAIPALLIGVVTIMYLDNGIASAKWLTTDEKQLLTREIEQDQ 243 Query: 241 K-GKESVHSFADIVSDKRVWLMCLIYFCFVMGQYGLTLWMPTLVKATGVTGNLHIGLLSA 299 K HS + SD RVW MCLIYF FV GQYGLT WMPTL+K+TGVTG +IGLLSA Sbjct: 244 KQAGTQKHSLGAVFSDARVWWMCLIYFAFVAGQYGLTFWMPTLIKSTGVTGAFNIGLLSA 303 Query: 300 IPFGCAIIAMNLIGRSADARRERRWHLIVPALMGAVGFVGAALFADNTAISIAALSLAAA 359 IPF CAI+ MNL+G SAD RRERRWHLIVPAL GAVGF AA FAD+T IS+ LS+AAA Sbjct: 304 IPFLCAIVVMNLLGHSADKRRERRWHLIVPALAGAVGFTAAASFADSTVISLICLSIAAA 363 Query: 360 GVLTCAPLFWSLPTSFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHSGATGMYM 419 GVLTCAPLFWSLPT+FLSG AAA GIA +NSVGNLAGF SPY+IGYLKDLT S A+GMY+ Sbjct: 364 GVLTCAPLFWSLPTAFLSGTAAAAGIAIVNSVGNLAGFASPYMIGYLKDLTQSTASGMYV 423 Query: 420 LAIMLVIGSAAVLKTSPKLVNK 441 LA +LVIG+ AV T +LVN+ Sbjct: 424 LAAVLVIGAIAVWFTPARLVNR 445 >A9BVT8.1 A9BVT8_DELAS Major facilitator superfamily MFS_1 Length = 443 Score = 655 bits (1691), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/440 (74%), Positives = 369/440 (83%), Gaps = 4/440 (0%) Query: 3 ASTNIGAAPAVNTSANEQEQNRVYAKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSVDL 62 AS GA PA A E R YAKVFWR++PFLMLCYVIAYLDRVNVGFAKLQMS DL Sbjct: 7 ASGQAGAHPA---QAASPETARAYAKVFWRLVPFLMLCYVIAYLDRVNVGFAKLQMSQDL 63 Query: 63 GFSETVFGLGAGVFFLGYFLFEVPSNILMHKVGARVWIARIMITWGILSAAFMYVETPMQ 122 GFSETVFGLGAGVFF+GYFLFEVPSN+LMH++GARVWIARIMITWGILSA FMYVETP Sbjct: 64 GFSETVFGLGAGVFFIGYFLFEVPSNLLMHRLGARVWIARIMITWGILSAMFMYVETPTG 123 Query: 123 FYVLRFLLGLAEAGFYPGIILYLTYWYPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDA 182 FY+LRFLLGLAEAGFYPG+ILYLTYWYP+HRRAK++A+FMS IPVAGI GNPLSGWIM A Sbjct: 124 FYILRFLLGLAEAGFYPGVILYLTYWYPAHRRAKIVALFMSAIPVAGIFGNPLSGWIMQA 183 Query: 183 FHGTTGMHGWQWMFVIEAVPAVLIGLATLAYLDNGIAKAKWLSAGEKKLLEDEIAADQKG 242 FHG G+HGWQWMF+IEA+PA++IG+ T+ YLDNGI+ AKWL+A EK+LL EI DQ+ Sbjct: 184 FHGDHGLHGWQWMFLIEAIPALVIGVVTIFYLDNGISSAKWLTASEKQLLAREIELDQQH 243 Query: 243 K-ESVHSFADIVSDKRVWLMCLIYFCFVMGQYGLTLWMPTLVKATGVTGNLHIGLLSAIP 301 HS + +D+RVW MCLIYF FV GQYGLT WMPTL+K+TGVTG L+IGLLSAIP Sbjct: 244 SGAQKHSLKAVFADRRVWWMCLIYFAFVAGQYGLTFWMPTLIKSTGVTGALNIGLLSAIP 303 Query: 302 FGCAIIAMNLIGRSADARRERRWHLIVPALMGAVGFVGAALFADNTAISIAALSLAAAGV 361 F CAI+ MNL+G SAD RRERRWHLIVPALMGAVGF A FADNT +S+ LSLAAAGV Sbjct: 304 FLCAIVVMNLMGHSADKRRERRWHLIVPALMGAVGFAMTAFFADNTVLSLIFLSLAAAGV 363 Query: 362 LTCAPLFWSLPTSFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHSGATGMYMLA 421 LTCAPLFWSLPT+FLSG AAA GIA +NSVGNLAGF SPY+IGYLKDLT S GM++LA Sbjct: 364 LTCAPLFWSLPTAFLSGTAAAAGIAIVNSVGNLAGFASPYMIGYLKDLTQSTQAGMFVLA 423 Query: 422 IMLVIGSAAVLKTSPKLVNK 441 +LV+G+ AV T K+VN+ Sbjct: 424 GVLVVGAIAVWLTPAKMVNR 443 >B1G020.1 B1G020_9BURK Major facilitator superfamily MFS_1 Length = 444 Score = 648 bits (1672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/422 (75%), Positives = 360/422 (85%), Gaps = 1/422 (0%) Query: 21 EQNRVYAKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSVDLGFSETVFGLGAGVFFLGY 80 E R Y KVFWRI+PFLMLCYV+AYLDRVNVGFAKLQMS DL FSETVFGLGAGVFF+GY Sbjct: 23 EIERTYKKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGVFFIGY 82 Query: 81 FLFEVPSNILMHKVGARVWIARIMITWGILSAAFMYVETPMQFYVLRFLLGLAEAGFYPG 140 FLFE+PSNILMHK+GAR+WIARIMITWG++SA F++V+TP QFY+LRFLLGLAEAGFYPG Sbjct: 83 FLFELPSNILMHKLGARIWIARIMITWGVMSALFVFVKTPAQFYILRFLLGLAEAGFYPG 142 Query: 141 IILYLTYWYPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHGTTGMHGWQWMFVIEA 200 +ILYLTYW+PSHRRAK+IAVFMS IPV+GI GNPLSGWIM +FH ++G+ GWQWMF+IEA Sbjct: 143 VILYLTYWFPSHRRAKIIAVFMSAIPVSGIFGNPLSGWIMQSFHNSSGLAGWQWMFLIEA 202 Query: 201 VPAVLIGLATLAYLDNGIAKAKWLSAGEKKLLEDEIAADQ-KGKESVHSFADIVSDKRVW 259 VPAV IG+AT+ YLDNGIA AKWLS EK+LL DEIAA Q K K S HS + D R W Sbjct: 203 VPAVAIGIATILYLDNGIASAKWLSEPEKRLLSDEIAASQPKEKASAHSLRAVFRDPRTW 262 Query: 260 LMCLIYFCFVMGQYGLTLWMPTLVKATGVTGNLHIGLLSAIPFGCAIIAMNLIGRSADAR 319 M LIYF FV GQYGLT WMPTL+K+TGV+G +IGLLSAIPF CAI+ MNL+G SAD R Sbjct: 263 WMSLIYFAFVTGQYGLTFWMPTLIKSTGVSGAFNIGLLSAIPFLCAIVVMNLMGHSADKR 322 Query: 320 RERRWHLIVPALMGAVGFVGAALFADNTAISIAALSLAAAGVLTCAPLFWSLPTSFLSGA 379 RERRWHLIVPAL GAVGF AA FA NT +SIA LSLAAAGVLTCAPLFWSLPT+F+SGA Sbjct: 323 RERRWHLIVPALFGAVGFTVAASFASNTVVSIAFLSLAAAGVLTCAPLFWSLPTAFMSGA 382 Query: 380 AAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHSGATGMYMLAIMLVIGSAAVLKTSPKLV 439 AA GIA INS+GNLAGF SPY+IGYLKDLTHS +GMY+LA MLVIG+ A T KLV Sbjct: 383 TAAAGIAIINSIGNLAGFASPYMIGYLKDLTHSTQSGMYVLAGMLVIGAIATWLTPAKLV 442 Query: 440 NK 441 N+ Sbjct: 443 NR 444 >E8YT54.1 E8YT54_9BURK Major facilitator superfamily MFS_1 Length = 444 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/422 (75%), Positives = 360/422 (85%), Gaps = 1/422 (0%) Query: 21 EQNRVYAKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSVDLGFSETVFGLGAGVFFLGY 80 E R Y KVFWRI+PFLMLCYV+AYLDRVNVGFAKLQMS DL FSETVFGLGAGVFF+GY Sbjct: 23 EVERTYKKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGVFFIGY 82 Query: 81 FLFEVPSNILMHKVGARVWIARIMITWGILSAAFMYVETPMQFYVLRFLLGLAEAGFYPG 140 FLFE+PSNILMHK+GAR+WIARIMITWG++SA F++V+TP QFY+LRFLLGLAEAGFYPG Sbjct: 83 FLFELPSNILMHKIGARIWIARIMITWGVMSALFVFVKTPAQFYILRFLLGLAEAGFYPG 142 Query: 141 IILYLTYWYPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHGTTGMHGWQWMFVIEA 200 +ILYLTYW+PSHRRAK+IAVFMS IPV+GI GNPLSGWIM AFH ++G+ GWQWMF+IEA Sbjct: 143 VILYLTYWFPSHRRAKIIAVFMSAIPVSGIFGNPLSGWIMQAFHNSSGLAGWQWMFLIEA 202 Query: 201 VPAVLIGLATLAYLDNGIAKAKWLSAGEKKLLEDEIAADQ-KGKESVHSFADIVSDKRVW 259 VPAV +G+AT+ YLDNGIA AKWLS EK+LL DEIAA Q K K + HS + D R W Sbjct: 203 VPAVAVGIATILYLDNGIAGAKWLSEPEKRLLADEIAASQPKQKANAHSLRAVFRDPRTW 262 Query: 260 LMCLIYFCFVMGQYGLTLWMPTLVKATGVTGNLHIGLLSAIPFGCAIIAMNLIGRSADAR 319 M LIYF FV GQYGLT WMPTL+K+TGV+G +IGLLSAIPF CAI+ MNL+G SAD R Sbjct: 263 WMSLIYFAFVTGQYGLTFWMPTLIKSTGVSGAFNIGLLSAIPFICAIVVMNLLGHSADKR 322 Query: 320 RERRWHLIVPALMGAVGFVGAALFADNTAISIAALSLAAAGVLTCAPLFWSLPTSFLSGA 379 RERRWHLIVPAL GAVGF AA FA NT +SIA LSLAAAGVLTCAPLFWSLPT+F+SGA Sbjct: 323 RERRWHLIVPALFGAVGFTVAASFASNTVVSIAFLSLAAAGVLTCAPLFWSLPTAFMSGA 382 Query: 380 AAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHSGATGMYMLAIMLVIGSAAVLKTSPKLV 439 AA GIA INS+GNLAGF SPY+IGYLKDLTHS +GMY+LA MLVIG+ A T KLV Sbjct: 383 TAAAGIAIINSIGNLAGFASPYMIGYLKDLTHSTQSGMYVLAGMLVIGAIATWLTPAKLV 442 Query: 440 NK 441 N+ Sbjct: 443 NR 444