BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0523.p (294 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ITJ2.1 D8ITJ2_HERSS Protoheme IX farnesyltransferase EC=2.5.1.- 533 e-149 A6T2T7.1 COXX_JANMA Protoheme IX farnesyltransferase EC=2.5.1.- 517 e-145 A4G936.1 COXX_HERAR Protoheme IX farnesyltransferase EC=2.5.1.- 513 e-143 F1VVP1.1 F1VVP1_9BURK Heme O synthase, protoheme IX farnesyltran... 486 e-135 D4X5W0.1 D4X5W0_9BURK Protoheme IX farnesyltransferase EC=2.5.1.- 426 e-117 >D8ITJ2.1 D8ITJ2_HERSS Protoheme IX farnesyltransferase EC=2.5.1.- Length = 297 Score = 533 bits (1373), Expect = e-149, Method: Compositional matrix adjust. Identities = 253/294 (86%), Positives = 279/294 (94%) Query: 1 LTAQPNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELPDWRKVVFATIGIWLLAGAAFA 60 LTAQPNRIAQYWALTKPRVTQLAVFCAVIGMFL+TP+LPDW KV+F T+GIWLLAGAAFA Sbjct: 4 LTAQPNRIAQYWALTKPRVTQLAVFCAVIGMFLSTPDLPDWHKVIFGTLGIWLLAGAAFA 63 Query: 61 INCLVEREIDSRMARTARRPMARGEITVAQTLVFSGVIGGMGMWVLYSLVNPLTMWLTLA 120 INCLVEREIDSRMARTARRPMARGEITV QTLVFSGV+GG+GMWVLY+LVNPLTMWLT A Sbjct: 64 INCLVEREIDSRMARTARRPMARGEITVGQTLVFSGVLGGLGMWVLYNLVNPLTMWLTFA 123 Query: 121 TFVGYAIIYTIILKPSTPQNIVIGGLSGAMPPALGWAAIANDVPMQAWILVLIIFIWTPP 180 TFVGYAIIYTI+LKP+T QNIVIGGL+GAMPPALGWAA+ANDVPMQAW+LV+IIFIWTPP Sbjct: 124 TFVGYAIIYTIVLKPATSQNIVIGGLAGAMPPALGWAAMANDVPMQAWVLVMIIFIWTPP 183 Query: 181 HFWALAMYRRDDYAKSGLPMLPITHGMKLTQFHILLYTIALIATTMLPFAVGMSGLIYLG 240 HFWALAMYRRDDYAKSGLPMLPITHGM +T+ H+L+YTIAL A ++LPFA+GMSGLIYLG Sbjct: 184 HFWALAMYRRDDYAKSGLPMLPITHGMDVTKLHVLMYTIALFAVSLLPFAIGMSGLIYLG 243 Query: 241 TAIVLGLIFFHYAWQIYRHYTDLIARKAFTFSIIYLSILFAALLVDHYLLFRTF 294 TA+VLG IFF Y+WQ+YR YTDLIARKAF +SI+YLSILFA LLVDHY LFR+F Sbjct: 244 TAVVLGAIFFWYSWQMYRRYTDLIARKAFAYSIVYLSILFAVLLVDHYFLFRSF 297 >A6T2T7.1 COXX_JANMA Protoheme IX farnesyltransferase EC=2.5.1.- Length = 294 Score = 517 bits (1332), Expect = e-145, Method: Compositional matrix adjust. Identities = 252/291 (86%), Positives = 271/291 (93%) Query: 1 LTAQPNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELPDWRKVVFATIGIWLLAGAAFA 60 LTA PNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELP W+ VV ATIGIWLLAGAAFA Sbjct: 4 LTASPNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELPSWKIVVAATIGIWLLAGAAFA 63 Query: 61 INCLVEREIDSRMARTARRPMARGEITVAQTLVFSGVIGGMGMWVLYSLVNPLTMWLTLA 120 INCLVEREIDSRMARTARRPMARGEITV QTLVFSG+IGG GMWVLY+ VNPLTMWLT A Sbjct: 64 INCLVEREIDSRMARTARRPMARGEITVPQTLVFSGLIGGAGMWVLYNFVNPLTMWLTFA 123 Query: 121 TFVGYAIIYTIILKPSTPQNIVIGGLSGAMPPALGWAAIANDVPMQAWILVLIIFIWTPP 180 TFVGYA+IYTIILKP+TPQNIVIGGLSGAMPPALGWAA+AND+PMQAWILVLIIFIWTPP Sbjct: 124 TFVGYAVIYTIILKPATPQNIVIGGLSGAMPPALGWAAVANDLPMQAWILVLIIFIWTPP 183 Query: 181 HFWALAMYRRDDYAKSGLPMLPITHGMKLTQFHILLYTIALIATTMLPFAVGMSGLIYLG 240 HFWALA+YRRD+YAKSGLPMLP+THG + TQFHI LYTIAL+ATTMLPFAVGMSGLIYL Sbjct: 184 HFWALALYRRDEYAKSGLPMLPVTHGTEFTQFHIWLYTIALVATTMLPFAVGMSGLIYLV 243 Query: 241 TAIVLGLIFFHYAWQIYRHYTDLIARKAFTFSIIYLSILFAALLVDHYLLF 291 + +L +IF YAWQ+YRHYTD+IARK F +SIIYLS+LFAALLVDHYL F Sbjct: 244 SVAILDIIFVWYAWQVYRHYTDMIARKMFAYSIIYLSLLFAALLVDHYLRF 294 >A4G936.1 COXX_HERAR Protoheme IX farnesyltransferase EC=2.5.1.- Length = 294 Score = 513 bits (1322), Expect = e-143, Method: Compositional matrix adjust. Identities = 252/291 (86%), Positives = 269/291 (92%) Query: 1 LTAQPNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELPDWRKVVFATIGIWLLAGAAFA 60 L NRIAQYWALTKPRVTQLAVFCAVIGMFLATP+LPDW+ V+ ATIGIWLLAGAAFA Sbjct: 4 LIVSSNRIAQYWALTKPRVTQLAVFCAVIGMFLATPDLPDWKIVIAATIGIWLLAGAAFA 63 Query: 61 INCLVEREIDSRMARTARRPMARGEITVAQTLVFSGVIGGMGMWVLYSLVNPLTMWLTLA 120 INCLVEREIDSRMARTARRPMA+GEITV QTLVFSGVIGG GMWVLY+ VNPLTMWLT A Sbjct: 64 INCLVEREIDSRMARTARRPMAQGEITVPQTLVFSGVIGGAGMWVLYNFVNPLTMWLTFA 123 Query: 121 TFVGYAIIYTIILKPSTPQNIVIGGLSGAMPPALGWAAIANDVPMQAWILVLIIFIWTPP 180 TFVGYA+IYTIILKP+TPQNIVIGGLSGAMPPALGWAA+AND+PMQAWILVLIIFIWTPP Sbjct: 124 TFVGYAVIYTIILKPATPQNIVIGGLSGAMPPALGWAAVANDLPMQAWILVLIIFIWTPP 183 Query: 181 HFWALAMYRRDDYAKSGLPMLPITHGMKLTQFHILLYTIALIATTMLPFAVGMSGLIYLG 240 HFWALA+YRRD+YAKSGLPMLPITHG TQFHI LYTIAL+ATTMLPFAVGMSGLIYL Sbjct: 184 HFWALALYRRDEYAKSGLPMLPITHGTAFTQFHIWLYTIALVATTMLPFAVGMSGLIYLV 243 Query: 241 TAIVLGLIFFHYAWQIYRHYTDLIARKAFTFSIIYLSILFAALLVDHYLLF 291 A VL +IF YAWQ+YRHYTD+IARK FT+SIIYLS+LFAALLVDHYL F Sbjct: 244 VAAVLDVIFMWYAWQVYRHYTDMIARKMFTYSIIYLSLLFAALLVDHYLRF 294 >F1VVP1.1 F1VVP1_9BURK Heme O synthase, protoheme IX farnesyltransferase Length = 295 Score = 486 bits (1250), Expect = e-135, Method: Compositional matrix adjust. Identities = 235/287 (81%), Positives = 261/287 (90%) Query: 2 TAQPNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELPDWRKVVFATIGIWLLAGAAFAI 61 ++ PNR AQYWALTKPRVTQLAVFCAVIGMFLATP+LPDWR + ATIGIWLLAGAAFA+ Sbjct: 6 SSTPNRFAQYWALTKPRVTQLAVFCAVIGMFLATPDLPDWRVALPATIGIWLLAGAAFAV 65 Query: 62 NCLVEREIDSRMARTARRPMARGEITVAQTLVFSGVIGGMGMWVLYSLVNPLTMWLTLAT 121 NCLVEREID+RMARTARRPMARG+ITV QTLVFS VIGG+G VLY VNPLTMWLT AT Sbjct: 66 NCLVEREIDARMARTARRPMARGDITVPQTLVFSAVIGGLGTGVLYYFVNPLTMWLTFAT 125 Query: 122 FVGYAIIYTIILKPSTPQNIVIGGLSGAMPPALGWAAIANDVPMQAWILVLIIFIWTPPH 181 FVGYAIIYTIILKP+TPQNIVIGGL+GAMPPALGWAAIANDVPMQAWILVLIIFIWTPPH Sbjct: 126 FVGYAIIYTIILKPATPQNIVIGGLAGAMPPALGWAAIANDVPMQAWILVLIIFIWTPPH 185 Query: 182 FWALAMYRRDDYAKSGLPMLPITHGMKLTQFHILLYTIALIATTMLPFAVGMSGLIYLGT 241 FW+LA+YRRDDYAKSGLPMLPITHGM TQFHI LYTIAL+ATT LP+AV MSGLIYL + Sbjct: 186 FWSLALYRRDDYAKSGLPMLPITHGMVFTQFHIWLYTIALVATTFLPYAVNMSGLIYLVS 245 Query: 242 AIVLGLIFFHYAWQIYRHYTDLIARKAFTFSIIYLSILFAALLVDHY 288 I+L ++F +AWQ+Y+HYTD ++RK F +SI+YL +LFAALLVDHY Sbjct: 246 VILLDIVFMWHAWQVYKHYTDQVSRKMFAYSILYLGLLFAALLVDHY 292 >D4X5W0.1 D4X5W0_9BURK Protoheme IX farnesyltransferase EC=2.5.1.- Length = 297 Score = 426 bits (1094), Expect = e-117, Method: Compositional matrix adjust. Identities = 201/286 (70%), Positives = 245/286 (85%) Query: 4 QPNRIAQYWALTKPRVTQLAVFCAVIGMFLATPELPDWRKVVFATIGIWLLAGAAFAINC 63 Q + QY LTKPRVTQLAVFCAVIGMFLA P +PD R+V+F TIGIWLLA AAFAINC Sbjct: 8 QSGLLRQYLVLTKPRVTQLAVFCAVIGMFLAVPGVPDMRRVLFGTIGIWLLAAAAFAINC 67 Query: 64 LVEREIDSRMARTARRPMARGEITVAQTLVFSGVIGGMGMWVLYSLVNPLTMWLTLATFV 123 L+E+E+D+RM RTARR ARG I+ Q L SG++GG+GM+VLY+LVNPLTMWLT ATFV Sbjct: 68 LIEQEVDARMLRTARRATARGTISAFQVLSLSGLLGGVGMFVLYTLVNPLTMWLTFATFV 127 Query: 124 GYAIIYTIILKPSTPQNIVIGGLSGAMPPALGWAAIANDVPMQAWILVLIIFIWTPPHFW 183 GYA+IYT+ILKP TPQNIVIGGLSGAMPPALGWAA+A+ VP +AW+LVLIIFIWTPPHFW Sbjct: 128 GYAVIYTVILKPRTPQNIVIGGLSGAMPPALGWAAVADSVPAEAWVLVLIIFIWTPPHFW 187 Query: 184 ALAMYRRDDYAKSGLPMLPITHGMKLTQFHILLYTIALIATTMLPFAVGMSGLIYLGTAI 243 ALA+YR DYAK+GLPMLP+THG + T+ HILLY++AL+ATT+LP+A+ MSG +YL +A+ Sbjct: 188 ALALYRNHDYAKAGLPMLPVTHGNQFTRLHILLYSVALVATTLLPYAIRMSGELYLLSAL 247 Query: 244 VLGLIFFHYAWQIYRHYTDLIARKAFTFSIIYLSILFAALLVDHYL 289 VLG +F YAW++YR Y+D +AR F FSI+YL++LF ALLVDH++ Sbjct: 248 VLGGMFVSYAWRLYRAYSDELARSMFRFSILYLALLFGALLVDHWV 293