BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0478.p (263 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISW8.1 D8ISW8_HERSS 1-(5-phosphoribosyl)-5-[(5-phosphoribosyla... 483 e-134 A2RQ24.1 A2RQ24_HERSE 1-(5-phosphoribosyl)-5-[(5-phosphoribosyla... 483 e-134 A6T377.1 HIS4_JANMA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylami... 483 e-134 A4G9I7.1 HIS4_HERAR 1-(5-phosphoribosyl)-5-[(5-phosphoribosylami... 474 e-132 C3XCD4.1 C3XCD4_OXAFO 1-(5-phosphoribosyl)-5-[(5-phosphoribosyla... 436 e-120 >D8ISW8.1 D8ISW8_HERSS 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase EC=5.3.1.16 Length = 265 Score = 483 bits (1243), Expect = e-134, Method: Compositional matrix adjust. Identities = 237/253 (93%), Positives = 243/253 (96%) Query: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSQDPAEMARHWLLQGARRLHLVDLNGAFAGKP 60 MLLIPAIDLKDGHCVRLKQGDMDQATVFS+DPAEMA HWL QGARRLHLVDLNGAFAGKP Sbjct: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSEDPAEMALHWLKQGARRLHLVDLNGAFAGKP 60 Query: 61 KNESAVKAILKAVRDFAVENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 KNE+AVKAILKAV FA ENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP Sbjct: 61 KNEAAVKAILKAVASFAEENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 Query: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEGYGCEAIVYTDIGR 180 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEV+DLA+KFEGYGCEAIVYTDIGR Sbjct: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVVDLAQKFEGYGCEAIVYTDIGR 180 Query: 181 DGMMGGVNIEATVRLAQAVAIPIIASGGVHNIKDVEALCGVQDEGIEAVICGRSIYEGTL 240 DGMMGGVNIEATVRLAQAV IPIIASGGVHN+ DVEALC V+DEGIEAVICGRSIYEGTL Sbjct: 181 DGMMGGVNIEATVRLAQAVTIPIIASGGVHNVGDVEALCRVEDEGIEAVICGRSIYEGTL 240 Query: 241 DLSSAQDRADELT 253 DL S QDRADELT Sbjct: 241 DLRSGQDRADELT 253 >A2RQ24.1 A2RQ24_HERSE 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase EC=5.3.1.16 Length = 265 Score = 483 bits (1243), Expect = e-134, Method: Compositional matrix adjust. Identities = 237/253 (93%), Positives = 243/253 (96%) Query: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSQDPAEMARHWLLQGARRLHLVDLNGAFAGKP 60 MLLIPAIDLKDGHCVRLKQGDMDQATVFS+DPAEMA HWL QGARRLHLVDLNGAFAGKP Sbjct: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSEDPAEMALHWLKQGARRLHLVDLNGAFAGKP 60 Query: 61 KNESAVKAILKAVRDFAVENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 KNE+AVKAILKAV FA ENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP Sbjct: 61 KNEAAVKAILKAVASFAEENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 Query: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEGYGCEAIVYTDIGR 180 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEV+DLA+KFEGYGCEAIVYTDIGR Sbjct: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVVDLAQKFEGYGCEAIVYTDIGR 180 Query: 181 DGMMGGVNIEATVRLAQAVAIPIIASGGVHNIKDVEALCGVQDEGIEAVICGRSIYEGTL 240 DGMMGGVNIEATVRLAQAV IPIIASGGVHN+ DVEALC V+DEGIEAVICGRSIYEGTL Sbjct: 181 DGMMGGVNIEATVRLAQAVTIPIIASGGVHNVGDVEALCRVEDEGIEAVICGRSIYEGTL 240 Query: 241 DLSSAQDRADELT 253 DL S QDRADELT Sbjct: 241 DLRSGQDRADELT 253 >A6T377.1 HIS4_JANMA 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase EC=5.3.1.16 Length = 261 Score = 483 bits (1242), Expect = e-134, Method: Compositional matrix adjust. Identities = 233/253 (92%), Positives = 246/253 (97%) Query: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSQDPAEMARHWLLQGARRLHLVDLNGAFAGKP 60 MLLIPAIDLKDGHCVRLKQGDMDQATVFS+DPAEMARHWLLQGARRLHLVDLNGAFAGKP Sbjct: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSEDPAEMARHWLLQGARRLHLVDLNGAFAGKP 60 Query: 61 KNESAVKAILKAVRDFAVENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 KNESAVK+IL+AVR++A +N +EEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP Sbjct: 61 KNESAVKSILQAVREYAEKNGIEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 Query: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEGYGCEAIVYTDIGR 180 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFE YGCE+I+YTDIGR Sbjct: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEDYGCESIIYTDIGR 180 Query: 181 DGMMGGVNIEATVRLAQAVAIPIIASGGVHNIKDVEALCGVQDEGIEAVICGRSIYEGTL 240 DGMMGGVNIEATV+LAQ++ IP+IASGGVHNIKDVEALC VQDEGIE VICGRSIYEGTL Sbjct: 181 DGMMGGVNIEATVKLAQSMTIPVIASGGVHNIKDVEALCAVQDEGIEGVICGRSIYEGTL 240 Query: 241 DLSSAQDRADELT 253 DL SAQDRADELT Sbjct: 241 DLRSAQDRADELT 253 >A4G9I7.1 HIS4_HERAR 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase EC=5.3.1.16 Length = 265 Score = 474 bits (1221), Expect = e-132, Method: Compositional matrix adjust. Identities = 229/253 (90%), Positives = 244/253 (96%) Query: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSQDPAEMARHWLLQGARRLHLVDLNGAFAGKP 60 MLLIPAIDLKDGHCVRLKQGDMDQATVFS+DPA+MARHWL QGARRLHLVDLNGAFAGKP Sbjct: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSEDPADMARHWLEQGARRLHLVDLNGAFAGKP 60 Query: 61 KNESAVKAILKAVRDFAVENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 KNE AVKAIL+AVR++A +N +EEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP Sbjct: 61 KNEPAVKAILQAVREYAEKNGIEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 Query: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEGYGCEAIVYTDIGR 180 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFE YGCE+I+YTDIGR Sbjct: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEDYGCESIIYTDIGR 180 Query: 181 DGMMGGVNIEATVRLAQAVAIPIIASGGVHNIKDVEALCGVQDEGIEAVICGRSIYEGTL 240 DGMMGGVNIEATV+LAQ++ IP+IASGGVHNIKDVEALC VQ+EGIE VICGRSIYEGTL Sbjct: 181 DGMMGGVNIEATVKLAQSMTIPVIASGGVHNIKDVEALCAVQEEGIEGVICGRSIYEGTL 240 Query: 241 DLSSAQDRADELT 253 DL SAQDRADEL+ Sbjct: 241 DLRSAQDRADELS 253 >C3XCD4.1 C3XCD4_OXAFO 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase EC=5.3.1.16 Length = 255 Score = 436 bits (1121), Expect = e-120, Method: Compositional matrix adjust. Identities = 211/253 (83%), Positives = 233/253 (92%) Query: 1 MLLIPAIDLKDGHCVRLKQGDMDQATVFSQDPAEMARHWLLQGARRLHLVDLNGAFAGKP 60 MLLIPAIDLKDG CVRLKQGDM+QATVFS+DPAEMA HWL QGARRLHLVDLNGAFAGKP Sbjct: 1 MLLIPAIDLKDGSCVRLKQGDMEQATVFSEDPAEMALHWLEQGARRLHLVDLNGAFAGKP 60 Query: 61 KNESAVKAILKAVRDFAVENEVEEIPVQLGGGIRDLDTIERYLDDGLSYIIIGTAAVKNP 120 NESAVK IL+ V+DFA +N+++EIPVQLGGGIRDLDTIERYLD GLSYIIIGTAAVKNP Sbjct: 61 VNESAVKNILQVVQDFAEDNDLDEIPVQLGGGIRDLDTIERYLDHGLSYIIIGTAAVKNP 120 Query: 121 GFLHDACSAFPGQIIVGLDAKDGKVATDGWSKLSGHEVIDLAKKFEGYGCEAIVYTDIGR 180 GFL DACS FPGQIIVGLDAKDGKVATDGWSKLS H+V++LAKK+E +G E+I+YTDIGR Sbjct: 121 GFLQDACSVFPGQIIVGLDAKDGKVATDGWSKLSRHDVVELAKKYESFGVESIIYTDIGR 180 Query: 181 DGMMGGVNIEATVRLAQAVAIPIIASGGVHNIKDVEALCGVQDEGIEAVICGRSIYEGTL 240 DGMMGGVN+EATV+LA+AV +P+IASGGVHNIKDVEALC VQ EGIE VICGRSIYEGTL Sbjct: 181 DGMMGGVNVEATVKLARAVKVPVIASGGVHNIKDVEALCEVQGEGIEGVICGRSIYEGTL 240 Query: 241 DLSSAQDRADELT 253 +L AQ RADEL+ Sbjct: 241 NLEEAQARADELS 253