BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0477.p (254 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISW7.1 D8ISW7_HERSS Imidazole glycerol phosphate synthase subu... 477 e-133 A6T376.1 HIS6_JANMA Imidazole glycerol phosphate synthase subuni... 459 e-127 A4G9I6.1 HIS6_HERAR Imidazole glycerol phosphate synthase subuni... 449 e-124 F1W3Z5.1 F1W3Z5_9BURK Imidazole glycerol phosphate synthase cycl... 442 e-122 A4JAW9.1 HIS6_BURVG Imidazole glycerol phosphate synthase subuni... 435 e-120 >D8ISW7.1 D8ISW7_HERSS Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 254 Score = 477 bits (1228), Expect = e-133, Method: Compositional matrix adjust. Identities = 237/254 (93%), Positives = 246/254 (96%) Query: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADEITFLDITASSDGR 60 M LAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADE+TFLDITASSDGR Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 Query: 61 GLLLDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINTSAVTNPQLVEDAASK 120 L+LDIIEAVASQVFIPLTVGGGVRAV+DVRRLLNAGADKVGINTSAVTNPQLV DAASK Sbjct: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 Query: 121 YGSQCIVVAIDAKRTGEGKWEVFTHGGRNATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 YGSQCIVVAIDAKR G+GKWEV+THGGR ATGLDAVEWARKMAQLGAGEILLTSMDRDGT Sbjct: 121 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 Query: 181 RSGFDLALTRAVSDAVAIPVIASGGVGGLQDLADGIKQGKADAVLAASIFHYGQHTVQEA 240 +SGFDL LTRAVS+AV+IPVIASGGVGGLQDLADGI +GKADAVLAASIFHYGQHTVQEA Sbjct: 181 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA 240 Query: 241 KRFMADQNIPMRLA 254 KRFMADQNI MRLA Sbjct: 241 KRFMADQNISMRLA 254 >A6T376.1 HIS6_JANMA Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 254 Score = 459 bits (1182), Expect = e-127, Method: Compositional matrix adjust. Identities = 224/253 (88%), Positives = 241/253 (95%) Query: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADEITFLDITASSDGR 60 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDP+EIARRYDEQGADEITFLDITA+SDGR Sbjct: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPIEIARRYDEQGADEITFLDITATSDGR 60 Query: 61 GLLLDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINTSAVTNPQLVEDAASK 120 L+LDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGIN+SA++NPQLV DA+ K Sbjct: 61 DLILDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINSSAISNPQLVFDASQK 120 Query: 121 YGSQCIVVAIDAKRTGEGKWEVFTHGGRNATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 YGSQCIVVAIDAK+ +G+WEVFTHGGR ATGLDAVEWA+KM LGAGEILLTSMDRDGT Sbjct: 121 YGSQCIVVAIDAKKASDGRWEVFTHGGRKATGLDAVEWAKKMQNLGAGEILLTSMDRDGT 180 Query: 181 RSGFDLALTRAVSDAVAIPVIASGGVGGLQDLADGIKQGKADAVLAASIFHYGQHTVQEA 240 + GFDL LTR+VSDA++IPVIASGGVGGLQDLADG+K G+ADAVLAASIFHYGQHTVQEA Sbjct: 181 KIGFDLDLTRSVSDAISIPVIASGGVGGLQDLADGVKVGRADAVLAASIFHYGQHTVQEA 240 Query: 241 KRFMADQNIPMRL 253 KRFMADQ IPMRL Sbjct: 241 KRFMADQGIPMRL 253 >A4G9I6.1 HIS6_HERAR Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 254 Score = 449 bits (1156), Expect = e-124, Method: Compositional matrix adjust. Identities = 218/253 (86%), Positives = 239/253 (94%) Query: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADEITFLDITASSDGR 60 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYD+QGADE+TFLDITA+SDGR Sbjct: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDDQGADELTFLDITATSDGR 60 Query: 61 GLLLDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINTSAVTNPQLVEDAASK 120 L+LDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGIN+SA++NPQLV DA+ K Sbjct: 61 DLILDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINSSAISNPQLVFDASQK 120 Query: 121 YGSQCIVVAIDAKRTGEGKWEVFTHGGRNATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 YGSQCIVVAIDAK+ +G+WEVFTHGGR ATGLDA+EWA+KM LGAGEILLTSMDRDGT Sbjct: 121 YGSQCIVVAIDAKKAADGRWEVFTHGGRKATGLDAIEWAKKMESLGAGEILLTSMDRDGT 180 Query: 181 RSGFDLALTRAVSDAVAIPVIASGGVGGLQDLADGIKQGKADAVLAASIFHYGQHTVQEA 240 + GFDL LTR+VSDA++IPVIASGGVGGLQDL DG+K G+ADAVLAASIFHYGQHTVQEA Sbjct: 181 KVGFDLDLTRSVSDAISIPVIASGGVGGLQDLVDGVKIGRADAVLAASIFHYGQHTVQEA 240 Query: 241 KRFMADQNIPMRL 253 KRFM++Q I MRL Sbjct: 241 KRFMSEQGIAMRL 253 >F1W3Z5.1 F1W3Z5_9BURK Imidazole glycerol phosphate synthase cyclase subunit Length = 254 Score = 442 bits (1137), Expect = e-122, Method: Compositional matrix adjust. Identities = 217/253 (85%), Positives = 234/253 (92%) Query: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADEITFLDITASSDGR 60 MTLAKRIIPCLDVTAGRVVKG+NFLELRDAGDPVEIARRYDEQGADEITFLDITA+SDGR Sbjct: 1 MTLAKRIIPCLDVTAGRVVKGINFLELRDAGDPVEIARRYDEQGADEITFLDITATSDGR 60 Query: 61 GLLLDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINTSAVTNPQLVEDAASK 120 L+L IIEAVAS VFIPLTVGGGVR V+DVRRLLNAGADKV IN+SA++NPQLV DAA K Sbjct: 61 DLILHIIEAVASTVFIPLTVGGGVRVVEDVRRLLNAGADKVSINSSAISNPQLVFDAAQK 120 Query: 121 YGSQCIVVAIDAKRTGEGKWEVFTHGGRNATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 +GSQCIVVAIDAKR+G+GKWEVFTHGGR ATGLD +EWA+KMA GAGE+LLTSMDRDGT Sbjct: 121 HGSQCIVVAIDAKRSGDGKWEVFTHGGRKATGLDVIEWAKKMAAFGAGELLLTSMDRDGT 180 Query: 181 RSGFDLALTRAVSDAVAIPVIASGGVGGLQDLADGIKQGKADAVLAASIFHYGQHTVQEA 240 RSGFDLALT AVSDAV IPVIASGGVGGLQDLADG+K GKADAVLAASIFHYG HT+ EA Sbjct: 181 RSGFDLALTAAVSDAVNIPVIASGGVGGLQDLADGVKIGKADAVLAASIFHYGHHTIAEA 240 Query: 241 KRFMADQNIPMRL 253 K+FMA Q I +RL Sbjct: 241 KQFMAAQQIAVRL 253 >A4JAW9.1 HIS6_BURVG Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 435 bits (1119), Expect = e-120, Method: Compositional matrix adjust. Identities = 219/257 (85%), Positives = 233/257 (90%), Gaps = 4/257 (1%) Query: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADEITFLDITASSDGR 60 M LAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYDEQGADE+TFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDEQGADELTFLDITATSDQR 60 Query: 61 GLLLDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINTSAVTNPQLVEDAASK 120 L+L IIEAVASQVFIPLTVGGGVRAV+DVRRLLNAGADKV +N+SAV NPQLV DAA K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADK 120 Query: 121 YGSQCIVVAIDAKRTG----EGKWEVFTHGGRNATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR +WEVFTHGGR ATGLDA+EWARKMA+LGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSAPNEAPRWEVFTHGGRKATGLDAIEWARKMAELGAGEILLTSMD 180 Query: 177 RDGTRSGFDLALTRAVSDAVAIPVIASGGVGGLQDLADGIKQGKADAVLAASIFHYGQHT 236 RDGT+SGFDLALTRAVSDAV +PVIASGGVG LQDLADGIKQG ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDLALTRAVSDAVPVPVIASGGVGCLQDLADGIKQGHADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNIPMRL 253 V EAK FMADQ I +RL Sbjct: 241 VGEAKHFMADQGIAVRL 257