BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0476.p         (153 letters)

Database: pfamseq 
           15,929,002 sequences; 5,169,768,107 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D8ISW6.1 D8ISW6_HERSS Phosphoribosyl-AMP cyclohydrolase protein ...   262   1e-68
A4G9I5.1 HIS3_HERAR Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19     237   4e-61
A6T375.1 HIS3_JANMA Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19     236   1e-60
F1W3Z4.1 F1W3Z4_9BURK Phosphoribosyl-AMP cyclohydrolase               231   3e-59
Q1LIB3.1 HIS3_RALME Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19     229   1e-58

>D8ISW6.1 D8ISW6_HERSS Phosphoribosyl-AMP cyclohydrolase protein EC=3.5.4.19
          Length = 166

 Score =  262 bits (670), Expect = 1e-68,   Method: Compositional matrix adjust.
 Identities = 134/165 (81%), Positives = 142/165 (86%), Gaps = 12/165 (7%)

Query: 1   MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKK 60
           MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTV+ G+AVYWSRSRKK
Sbjct: 1   MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK 60

Query: 61  LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQ 120
           LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEG+A++GEW 
Sbjct: 61  LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV 120

Query: 121 TVEPVLKD-----------EAAPEKEKPKRVRKTMTK-TDPKVTP 153
           TVEPVLKD            AA  + KPKRVRK++ K  D   TP
Sbjct: 121 TVEPVLKDLQPGAGGGPAATAAEPEAKPKRVRKSIPKPVDSDKTP 165


>A4G9I5.1 HIS3_HERAR Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19
          Length = 134

 Score =  237 bits (604), Expect = 4e-61,   Method: Compositional matrix adjust.
 Identities = 109/128 (85%), Positives = 122/128 (95%)

Query: 1   MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKK 60
           MS +AKWLNKVKWDE GLVPVIAQEVGSNDVLMFAWMNR+ALA+T+++GEA+YWSRSRKK
Sbjct: 1   MSSNAKWLNKVKWDEHGLVPVIAQEVGSNDVLMFAWMNRDALAKTIESGEAIYWSRSRKK 60

Query: 61  LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQ 120
           LWHKGEESGH QKVHE+RLDCDEDVVLLKVEQV  IACHTGRHSCFFQKFEG+A+ G+W+
Sbjct: 61  LWHKGEESGHTQKVHEVRLDCDEDVVLLKVEQVGAIACHTGRHSCFFQKFEGDAKEGDWE 120

Query: 121 TVEPVLKD 128
           TVEPVLK+
Sbjct: 121 TVEPVLKN 128


>A6T375.1 HIS3_JANMA Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19
          Length = 134

 Score =  236 bits (601), Expect = 1e-60,   Method: Compositional matrix adjust.
 Identities = 109/128 (85%), Positives = 121/128 (94%)

Query: 1   MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKK 60
           MS +AKWLNKVKWDE GLVPVIAQEVG+NDVLMFAWMNR+ALA+T++TGEA+YWSRSRKK
Sbjct: 1   MSSNAKWLNKVKWDEHGLVPVIAQEVGTNDVLMFAWMNRDALAKTIETGEAIYWSRSRKK 60

Query: 61  LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQ 120
           LWHKGEESGH QKVHE+RLDCDEDVVLLKVEQV  IACHTGRHSCFFQKFEG A+ G+W+
Sbjct: 61  LWHKGEESGHTQKVHEVRLDCDEDVVLLKVEQVGKIACHTGRHSCFFQKFEGGAKDGDWE 120

Query: 121 TVEPVLKD 128
           TVEPVLK+
Sbjct: 121 TVEPVLKN 128


>F1W3Z4.1 F1W3Z4_9BURK Phosphoribosyl-AMP cyclohydrolase
          Length = 134

 Score =  231 bits (589), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 109/134 (81%), Positives = 117/134 (87%)

Query: 1   MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKK 60
           MSI AKWLNKVKWDE GLVPVIAQE+GSNDVLMFAWMNR+AL RTV++GEAVYWSRSRKK
Sbjct: 1   MSIKAKWLNKVKWDEYGLVPVIAQELGSNDVLMFAWMNRDALERTVESGEAVYWSRSRKK 60

Query: 61  LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQ 120
           LWHKGEESGH QKVH+IRLDCDEDVVLLKVEQ   IACHTGRHSCFFQKFEG    GEW 
Sbjct: 61  LWHKGEESGHTQKVHDIRLDCDEDVVLLKVEQTGNIACHTGRHSCFFQKFEGTVGDGEWV 120

Query: 121 TVEPVLKDEAAPEK 134
           + +PVL D A+  K
Sbjct: 121 SADPVLVDPASIYK 134


>Q1LIB3.1 HIS3_RALME Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19
          Length = 135

 Score =  229 bits (584), Expect = 1e-58,   Method: Compositional matrix adjust.
 Identities = 106/135 (78%), Positives = 120/135 (88%)

Query: 3   ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKKLW 62
           ++ KWLNKVKWD+ GLVPVI QEVGSNDVLMFA+MNR+AL RTV+ GEAV+WSRSRK+LW
Sbjct: 1   MAKKWLNKVKWDDNGLVPVIVQEVGSNDVLMFAFMNRDALQRTVELGEAVFWSRSRKRLW 60

Query: 63  HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQTV 122
           HKGEESGH QKVHEIRLDCDEDVVLLKV Q+  IACHTGRHSCFFQKFEG+ E+G+WQTV
Sbjct: 61  HKGEESGHVQKVHEIRLDCDEDVVLLKVTQIDSIACHTGRHSCFFQKFEGDVESGDWQTV 120

Query: 123 EPVLKDEAAPEKEKP 137
           EPVLKD ++    KP
Sbjct: 121 EPVLKDPSSIYAAKP 135