BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0336.p (304 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IQC6.1 D8IQC6_HERSS Coproporphyrinogen-III oxidase, aerobic EC... 521 e-146 A6SVD5.1 A6SVD5_JANMA Coproporphyrinogen-III oxidase, aerobic EC... 505 e-141 A4G2M5.1 A4G2M5_HERAR Coproporphyrinogen-III oxidase, aerobic EC... 503 e-140 F1VZG2.1 F1VZG2_9BURK Coproporphyrinogen III oxidase, aerobic 498 e-139 Q1H4H0.1 HEM6_METFK Coproporphyrinogen-III oxidase, aerobic EC=1... 470 e-130 >D8IQC6.1 D8IQC6_HERSS Coproporphyrinogen-III oxidase, aerobic EC=1.3.3.3 Length = 324 Score = 521 bits (1341), Expect = e-146, Method: Compositional matrix adjust. Identities = 243/303 (80%), Positives = 267/303 (88%), Gaps = 2/303 (0%) Query: 2 TATATASTIKAYLQDLQHRIVAALEGVDGKSFLTDSWERPEGGGGISRIIEEGNVFERGG 61 A+ + +KAYLQDLQ RIVAALE DGKSFL+DSWERPEGGGG SR++EEGN+ ERGG Sbjct: 24 NASTNTAAVKAYLQDLQQRIVAALEAADGKSFLSDSWERPEGGGGTSRLLEEGNLLERGG 83 Query: 62 VGFSHVMGKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNPYAPTVHMNVRFFVAKADGQ 121 VGFSHVMGKNLPPSAAANRP +AGR WEAMGVSLVLHPRNPY PTVHMNVRFF A+G+ Sbjct: 84 VGFSHVMGKNLPPSAAANRPHLAGRAWEAMGVSLVLHPRNPYVPTVHMNVRFFTTHAEGE 143 Query: 122 NQEPVWWFGGGMDLTPYYGFAEDATHFHRSCRDALAPFGDELHPRFKKWCDEYFYLKHRK 181 E VWWFGGGMDLTPYYG +DA HFHR+CRDAL P+GDEL+PRFK WCD+YFYLKHRK Sbjct: 144 --EAVWWFGGGMDLTPYYGVEDDARHFHRTCRDALQPYGDELYPRFKTWCDDYFYLKHRK 201 Query: 182 EARGVGGIFFDDFNALPLDESFALMRSVGDGFIGAYLPILELRKDTPYGERERDFQAYRR 241 E RGVGGIFFDDFNALP +++FA+ RSVGD F+ AYLPI+ R+DTPYGERERDFQAYRR Sbjct: 202 EPRGVGGIFFDDFNALPFEQAFAMQRSVGDAFLAAYLPIVAARRDTPYGERERDFQAYRR 261 Query: 242 GRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVVKWRYDWQPPDGSPEARLYSDFLPHK 301 GRYVEFNLVFDRGTLFGLQSGGRTESILMSMPP+VKWRYDW P GSPEA LYSDFL HK Sbjct: 262 GRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPLVKWRYDWHPEPGSPEAALYSDFLVHK 321 Query: 302 EWI 304 EW+ Sbjct: 322 EWL 324 >A6SVD5.1 A6SVD5_JANMA Coproporphyrinogen-III oxidase, aerobic EC=1.3.3.3 Length = 332 Score = 505 bits (1300), Expect = e-141, Method: Compositional matrix adjust. Identities = 238/299 (79%), Positives = 262/299 (87%), Gaps = 2/299 (0%) Query: 6 TASTIKAYLQDLQHRIVAALEGVDGKSFLTDSWERPEGGGGISRIIEEGNVFERGGVGFS 65 + + +K YL LQ RIVAALE VDGK+F TDSW+RPEGGGGISRIIE GNVFERGGVGFS Sbjct: 36 SPAAVKEYLLGLQARIVAALEAVDGKAFGTDSWQRPEGGGGISRIIENGNVFERGGVGFS 95 Query: 66 HVMGKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNPYAPTVHMNVRFFVAKADGQNQEP 125 HVMGKNLPPSAAANRPE+AGR WEAMGVSLVLHPRNPYAPTVHMNVRFF A A+GQ+ Sbjct: 96 HVMGKNLPPSAAANRPELAGRNWEAMGVSLVLHPRNPYAPTVHMNVRFFTATAEGQDA-- 153 Query: 126 VWWFGGGMDLTPYYGFAEDATHFHRSCRDALAPFGDELHPRFKKWCDEYFYLKHRKEARG 185 +WWFGGGMDLTPYYGF EDA HFH++CRDAL FGD++HPR+KKWCD+YFYLKHR+E RG Sbjct: 154 IWWFGGGMDLTPYYGFEEDALHFHQTCRDALQAFGDDVHPRYKKWCDDYFYLKHRQEPRG 213 Query: 186 VGGIFFDDFNALPLDESFALMRSVGDGFIGAYLPILELRKDTPYGERERDFQAYRRGRYV 245 VGGIFFDD N + FAL +SVGD FI AYLP+L+ R DTPYGERERDFQ YRRGRYV Sbjct: 214 VGGIFFDDLNTPDFAQCFALQQSVGDHFIAAYLPLLQKRMDTPYGERERDFQTYRRGRYV 273 Query: 246 EFNLVFDRGTLFGLQSGGRTESILMSMPPVVKWRYDWQPPDGSPEARLYSDFLPHKEWI 304 EFNLVFDRGTLFGLQSGGRTESILMSMPPVV WRY+WQP GSPEARLYSDFL H++W+ Sbjct: 274 EFNLVFDRGTLFGLQSGGRTESILMSMPPVVTWRYNWQPEAGSPEARLYSDFLIHRDWV 332 >A4G2M5.1 A4G2M5_HERAR Coproporphyrinogen-III oxidase, aerobic EC=1.3.3.3 Length = 325 Score = 503 bits (1296), Expect = e-140, Method: Compositional matrix adjust. Identities = 237/304 (77%), Positives = 265/304 (87%), Gaps = 2/304 (0%) Query: 1 VTATATASTIKAYLQDLQHRIVAALEGVDGKSFLTDSWERPEGGGGISRIIEEGNVFERG 60 + + +++S +K YL LQ RIV+ALE VDG++F TDSWERPEGGGGISRIIE GNVFERG Sbjct: 24 IASPSSSSAVKEYLLGLQQRIVSALEEVDGQAFGTDSWERPEGGGGISRIIENGNVFERG 83 Query: 61 GVGFSHVMGKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNPYAPTVHMNVRFFVAKADG 120 GVGFSHVMGKNLPPSAAANRPE+AGR WEAMGVSLVLHPRNPYAPTVHMNVRFF+A +G Sbjct: 84 GVGFSHVMGKNLPPSAAANRPELAGRNWEAMGVSLVLHPRNPYAPTVHMNVRFFIASTEG 143 Query: 121 QNQEPVWWFGGGMDLTPYYGFAEDATHFHRSCRDALAPFGDELHPRFKKWCDEYFYLKHR 180 EP+WWFGGGMDLTPYYGF +DA HFH+ CRDAL FGDE+HPR+KKWCD+YFYLKHR Sbjct: 144 A--EPIWWFGGGMDLTPYYGFEDDARHFHQVCRDALLAFGDEVHPRYKKWCDDYFYLKHR 201 Query: 181 KEARGVGGIFFDDFNALPLDESFALMRSVGDGFIGAYLPILELRKDTPYGERERDFQAYR 240 +E RGVGGIFFDD N + FAL +SVG+ F+ AY+PIL+LRKD PYGERERDFQ YR Sbjct: 202 QEPRGVGGIFFDDLNEGGFERCFALQQSVGNHFVEAYVPILKLRKDMPYGERERDFQTYR 261 Query: 241 RGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVVKWRYDWQPPDGSPEARLYSDFLPH 300 RGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVV WRY+WQP GS EARL+SDFL H Sbjct: 262 RGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVVTWRYNWQPEAGSAEARLHSDFLIH 321 Query: 301 KEWI 304 +EWI Sbjct: 322 REWI 325 >F1VZG2.1 F1VZG2_9BURK Coproporphyrinogen III oxidase, aerobic Length = 304 Score = 498 bits (1281), Expect = e-139, Method: Compositional matrix adjust. Identities = 236/302 (78%), Positives = 263/302 (87%), Gaps = 2/302 (0%) Query: 3 ATATASTIKAYLQDLQHRIVAALEGVDGKSFLTDSWERPEGGGGISRIIEEGNVFERGGV 62 A TASTIK YL DLQ RIV AL +DG+ F TD+W+RPEGGGGISRIIE+GNVFERGGV Sbjct: 4 AITTASTIKTYLLDLQERIVTALSAIDGQPFSTDAWQRPEGGGGISRIIEDGNVFERGGV 63 Query: 63 GFSHVMGKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNPYAPTVHMNVRFFVAKADGQN 122 GFSHV GKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNP APTVHMNVRFF+A A G+ Sbjct: 64 GFSHVTGKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNPLAPTVHMNVRFFMATAAGE- 122 Query: 123 QEPVWWFGGGMDLTPYYGFAEDATHFHRSCRDALAPFGDELHPRFKKWCDEYFYLKHRKE 182 PVWWFGGGMDLTPYYGF +DA HFH++C DALAPFGD+LHPRFKKWCDEYF+LKHR+E Sbjct: 123 -APVWWFGGGMDLTPYYGFEDDARHFHQTCFDALAPFGDDLHPRFKKWCDEYFFLKHRQE 181 Query: 183 ARGVGGIFFDDFNALPLDESFALMRSVGDGFIGAYLPILELRKDTPYGERERDFQAYRRG 242 RG+GGIFFDDF+AL LD S A+M+SVGD F+ AYLPIL+ RKD P+ E +RDFQAYRRG Sbjct: 182 PRGIGGIFFDDFHALGLDRSSAMMQSVGDAFLAAYLPILQRRKDLPFDETQRDFQAYRRG 241 Query: 243 RYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVVKWRYDWQPPDGSPEARLYSDFLPHKE 302 RYVEFNLV+DRGTLFGLQSGGRTESILMSMPPVVKWRY+W P G+ EA LY FL ++ Sbjct: 242 RYVEFNLVYDRGTLFGLQSGGRTESILMSMPPVVKWRYNWTPLPGTAEAALYEQFLVQRD 301 Query: 303 WI 304 W+ Sbjct: 302 WL 303 >Q1H4H0.1 HEM6_METFK Coproporphyrinogen-III oxidase, aerobic EC=1.3.3.3 Length = 302 Score = 470 bits (1210), Expect = e-130, Method: Compositional matrix adjust. Identities = 219/297 (73%), Positives = 252/297 (84%), Gaps = 2/297 (0%) Query: 8 STIKAYLQDLQHRIVAALEGVDGKSFLTDSWERPEGGGGISRIIEEGNVFERGGVGFSHV 67 + I YLQ LQ RIV A+E VDGK FL DSW+R EGGGG S ++EEGNVFER G+GFSHV Sbjct: 4 TAIFDYLQGLQTRIVEAIELVDGKRFLHDSWQRAEGGGGTSCMLEEGNVFERAGIGFSHV 63 Query: 68 MGKNLPPSAAANRPEIAGREWEAMGVSLVLHPRNPYAPTVHMNVRFFVAKADGQNQEPVW 127 +G LPPSA+ PE AGR W+AMGVSLV HPRNPY PTVHMNVRFFVA+ G+ EP+W Sbjct: 64 IGNKLPPSASVAHPEAAGRSWQAMGVSLVFHPRNPYVPTVHMNVRFFVAEKPGE--EPIW 121 Query: 128 WFGGGMDLTPYYGFAEDATHFHRSCRDALAPFGDELHPRFKKWCDEYFYLKHRKEARGVG 187 WFGGGMDLTPYYGF EDA HFHR+CRDA+APFG++ +PRFKK CD+YFYLKHRKEARG+G Sbjct: 122 WFGGGMDLTPYYGFEEDAVHFHRTCRDAVAPFGEQYYPRFKKECDDYFYLKHRKEARGIG 181 Query: 188 GIFFDDFNALPLDESFALMRSVGDGFIGAYLPILELRKDTPYGERERDFQAYRRGRYVEF 247 GIFFDDFN L ++SFA RSVGD FI AYLPI++ RKD PY ERERDFQAYRRGRYVEF Sbjct: 182 GIFFDDFNELGFEQSFAFQRSVGDAFINAYLPIVQRRKDIPYSERERDFQAYRRGRYVEF 241 Query: 248 NLVFDRGTLFGLQSGGRTESILMSMPPVVKWRYDWQPPDGSPEARLYSDFLPHKEWI 304 NL++DRGT+FGLQS GRTESIL+SMPP+VKWRYDW+P GSPEARLYSDF+ ++W+ Sbjct: 242 NLIYDRGTIFGLQSNGRTESILLSMPPIVKWRYDWKPEAGSPEARLYSDFITGRDWL 298