BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0270.p (546 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWH4.1 D8IWH4_HERSS Two component sensor histidine kinase protein 535 e-150 B2T351.1 B2T351_BURPP Histidine kinase 492 e-137 B5WRM1.1 B5WRM1_9BURK Integral membrane sensor signal transducti... 491 e-137 D5W6U4.1 D5W6U4_BURSC Multi-sensor signal transduction histidine... 489 e-136 Q140Y3.1 Q140Y3_BURXL Signal Transduction Histidine Kinases (STHK) 489 e-136 >D8IWH4.1 D8IWH4_HERSS Two component sensor histidine kinase protein Length = 535 Score = 535 bits (1378), Expect = e-150, Method: Compositional matrix adjust. Identities = 274/531 (51%), Positives = 367/531 (69%), Gaps = 4/531 (0%) Query: 1 MKLFRKGLLLVAIPGIFELGLLGILYKSQENATQAEVLALHTKNVIIQAGEVREPVLLQS 60 M+L KGLL+VAIPG+FE+ LL L+KSQ +A AE A H+ VI +A +VREP+LL+S Sbjct: 1 MRLLTKGLLIVAIPGLFEIVLLAALFKSQADAADAERWAAHSAEVINKAADVREPLLLES 60 Query: 61 ARLRAAIILNDPAGLEKSDLWDSIEKELGELRELVGDNAEQLRRVAQIGASVQEYRQWTD 120 AR+R AII++DP+ + + +LW +E +LG+L LV DN EQ V + V ++R W D Sbjct: 61 ARIRNAIIIDDPSPISRPELWTDLEIKLGDLARLVSDNPEQSHSVQALRELVGQFRVWAD 120 Query: 121 LQTELLRNDKHDELVAALRDPNARRLIQVIQRQLVEFIKVEEELDQERLSSVVEARRMQN 180 E ++ + DELV LRD + +L F+ E L R ++ AR+ Q Sbjct: 121 SARERMQRGQRDELVRQLRDEQGPHRLSDFLNRLDGFLNEERHLGSLRNQALQSARQTQT 180 Query: 181 IALVIALLGSVLAAALAARIFSHDVGGRLAVLTGNAHKLTEGGVLAQRVGGNDEITELDK 240 L+ A++GS+LAAALA+ F+ +GGR++VL NA +L +G LA RV G+DEI+ LD Sbjct: 181 AWLIAAVIGSILAAALASVAFTRSIGGRISVLIVNARRLADGLPLAARVKGHDEISLLDD 240 Query: 241 VLHESSARLRQAEEDARVYREELERHAHELTSVNDDLQRQTQDNEMFIYSVSHDLRSPLV 300 LH SS RL++A + + YR +LER A ELT +N DL +QTQDNEMFIYSVSHDLRSPLV Sbjct: 241 ALHRSSERLQEASQQSEQYRSQLERRARELTELNADLLQQTQDNEMFIYSVSHDLRSPLV 300 Query: 301 NLQGFSKELHHSVGELHETIDASDLNDKDKQRIRDIIEDDVEVSLRFIRTAVTRSAAIID 360 NLQGFSKE+ H+ +L + A + D DK ++R ++ DD++ +LRFI+ AVTRSA IID Sbjct: 301 NLQGFSKEIGHATTDLLNAVQALPVPDADKAKLRSVVADDIQPALRFIQNAVTRSAGIID 360 Query: 361 AMLRLSRVGRVEYQSQETNVNEVVGRVIDAMSNTIRERQAVV-VSQPLPPCYGDPTAVEQ 419 +MLRLSR GRVEYQ ++N + R++ AMS +IR++ AVV V+ LPP +GDPTA+EQ Sbjct: 361 SMLRLSRAGRVEYQPVMLDMNVIAQRIVAAMSGSIRDKGAVVEVAPELPPAFGDPTAIEQ 420 Query: 420 IFGNLIGNAVNYLNPKRAGTVEIGVLPPDPGQ---PDFRTYYVRDNGLGIPADYLGKMFS 476 + GNL+GNAVNYL+P R G + I L + G P+ Y VRDNGLGIP Y+ KMF Sbjct: 421 VLGNLVGNAVNYLDPARPGRITIDHLREEGGAATGPETNVYVVRDNGLGIPPAYMHKMFI 480 Query: 477 AFHRLHADIAQGEGVGLALIKRIVLRHGGKIWVESTEGAGTTFYTSLPVRP 527 AF RLH + A GEG+GLAL+KR+V RHGG+IWVESTEG G++FY +LP RP Sbjct: 481 AFQRLHGNAAPGEGIGLALVKRVVERHGGRIWVESTEGQGSSFYVALPARP 531 >B2T351.1 B2T351_BURPP Histidine kinase Length = 582 Score = 492 bits (1266), Expect = e-137, Method: Compositional matrix adjust. Identities = 258/542 (47%), Positives = 357/542 (65%), Gaps = 3/542 (0%) Query: 1 MKLFRKGLLLVAIPGIFELGLLGILYKSQENATQAEVLALHTKNVIIQAGEVREPVLLQS 60 M+L KGLLL+AIP +FEL LL L K+Q +A QAE A+H+++V+ Q + +PVL +S Sbjct: 1 MRLTTKGLLLIAIPALFELALLSGLVKAQSDAAQAERWAVHSQDVLRQTTAILDPVLGES 60 Query: 61 ARLRAAIILNDPAGLEKSDLWDSIEKELGELRELVGDNAEQLRRVAQIGASVQEYRQWTD 120 LR A++ ND +W +++ + +L ELV DN Q+ RV Q+ SVQ YRQW+D Sbjct: 61 VALRGAVLANDARFSTPVSVWVDVDRRIDQLAELVADNPAQVERVVQVRQSVQAYRQWSD 120 Query: 121 LQTELLRNDKHDELVAALRDPNARRLIQVIQRQLVEFIKVEEELDQERLSSVVEARRMQN 180 ++L + + +++A R+ ++ ++Q+ F E LD R ++ AR Q Sbjct: 121 RIQDMLHSGRRRDVLARFRELAPADVLDRFRQQVAAFQAEERRLDTLRSNAADAARERQQ 180 Query: 181 IALVIALLGSVLAAALAARIFSHDVGGRLAVLTGNAHKLTEGGVLAQRVGGNDEITELDK 240 ++ A+LGS+L ALA +F+ V GRLAVL NA +L LA G+DEI LD Sbjct: 181 TLVLAAVLGSLLFVALAVWLFTRGVRGRLAVLADNAGRLAGNEPLAPIGPGHDEIARLDL 240 Query: 241 VLHESSARLRQAEEDARVYREELERHAHELTSVNDDLQRQTQDNEMFIYSVSHDLRSPLV 300 LHE+S RL +AE +R +L R EL +N++L++QTQ+NEMFIYSVSHDLR+PLV Sbjct: 241 TLHETSRRLLEAERIQARFRADLARRTGELARINENLRQQTQENEMFIYSVSHDLRAPLV 300 Query: 301 NLQGFSKELHHSVGELHETIDASDLNDKDKQRIRDIIEDDVEVSLRFIRTAVTRSAAIID 360 NLQGFSKEL S EL + S L + +QRI ++++D+ +L +++TAV R++ IID Sbjct: 301 NLQGFSKELIRSCDELRAAVRESSLAAQTRQRIERVVDEDIGEALHYLQTAVLRASHIID 360 Query: 361 AMLRLSRVGRVEYQSQETNVNEVVGRVIDAMSNTIRERQAVVVSQPLPPCYGDPTAVEQI 420 A+L LSRVGRVEY+ Q+ V ++V RVIDAM +IR R+A+V LP +GDPTA+EQ+ Sbjct: 361 ALLHLSRVGRVEYRQQKVEVRDIVPRVIDAMQGSIRARRALVSVDELPAVWGDPTALEQV 420 Query: 421 FGNLIGNAVNYLNPKRAGTVEIGVLPPDPGQPDFRTYYVRDNGLGIPADYLGKMFSAFHR 480 F NLIGNAVNYL+P R G +EIG P PG R +YVRDNGLGIPA L ++F+AF R Sbjct: 421 FANLIGNAVNYLDPSREGRIEIGTTPAPPGVHSLRIFYVRDNGLGIPAVALPRLFNAFQR 480 Query: 481 LHADIAQGEGVGLALIKRIVLRHGGKIWVESTEGAGTTFYTSLP---VRPIQQVTPPATQ 537 LH ++A GEG+GLAL++R+V RHGG++W ES EG GTTFY SLP R QQ + + Sbjct: 481 LHGNVAAGEGIGLALVRRVVERHGGRVWAESKEGVGTTFYLSLPEAGARIAQQAAGTSAR 540 Query: 538 LA 539 LA Sbjct: 541 LA 542 >B5WRM1.1 B5WRM1_9BURK Integral membrane sensor signal transduction histidine kinase Length = 536 Score = 491 bits (1265), Expect = e-137, Method: Compositional matrix adjust. Identities = 252/535 (47%), Positives = 352/535 (65%), Gaps = 6/535 (1%) Query: 1 MKLFRKGLLLVAIPGIFELGLLGILYKSQENATQAEVLALHTKNVIIQAGEVREPVLLQS 60 MKLF KGLLL+AIP + EL LLG+++ +QE QA ++K ++ Q+ + +P+L Q+ Sbjct: 1 MKLFTKGLLLIAIPSVVELALLGVVFDTQEQTAQAAQWVDNSKQILYQSSAIVDPLLRQA 60 Query: 61 ARLRAAIILNDPAGLEKSDLWDSIEKELGELRELVGDNAEQLRRVAQIGASVQEYRQWTD 120 AR+R A++ D + +++ +W + L +L LV D Q RV + ++ YR+ + Sbjct: 61 ARVRTAMVTGDASLIDRHAVWVDLNDRLAKLDTLVADTPPQAERVRNMRRAIDAYREQSV 120 Query: 121 LQTELLRNDKHDELVAALRDPNARRLIQVIQRQLVEFIKVEEELDQERLSSVVEARRMQN 180 + L ++ AL R I V + +L +F ELD ER +++ E R +Q Sbjct: 121 AISRALHEERSLRPYIALETDALPRQIAVFRDELAQFGAAASELDVERSTALGERRELQQ 180 Query: 181 IALVIALLGSVLAAALAARIFSHDVGGRLAVLTGNAHKLTEGGVLAQRVGGNDEITELDK 240 A + A+ GS+L A+ A +F+ +G RL VLT NA +L G LA + G+DEI LD Sbjct: 181 TAQIAAVFGSMLIWAVTAFVFARGIGQRLEVLTDNAERLGSGRPLAAPLSGSDEIAALDT 240 Query: 241 VLHESSARLRQAEEDARVYREELERHAHELTSVNDDLQRQTQDNEMFIYSVSHDLRSPLV 300 VLH++ ARLR+AE + + +LE A EL +VN++L+++TQDNEMFIYSVSHDLRSPLV Sbjct: 241 VLHQTDARLREAEAEQAALKIQLEARARELAAVNEELRQETQDNEMFIYSVSHDLRSPLV 300 Query: 301 NLQGFSKELHHSVGELHETIDASDLNDKDKQRIRDIIEDDVEVSLRFIRTAVTRSAAIID 360 NLQGFSKELH S EL I + L +++R+ I++ DV SL ++RTAV R+AAIID Sbjct: 301 NLQGFSKELHVSCDELDGIIGQARLPGNEQRRMTHILDGDVRESLHYLRTAVARAAAIID 360 Query: 361 AMLRLSRVGRVEYQSQETNVNEVVGRVIDAMSNTIRERQAVVVSQPLPPCYGDPTAVEQI 420 A+LR+SR GR EYQ Q +V V RV+DA+ T+ +R + + LPP +GDPTAVEQI Sbjct: 361 ALLRISRAGRFEYQWQRVSVGRAVARVVDALQGTLDQRAVSITVRELPPAWGDPTAVEQI 420 Query: 421 FGNLIGNAVNYLNPKRAGTVEIGVLPPDP---GQP---DFRTYYVRDNGLGIPADYLGKM 474 F NLIGNA+N+L+P R G +E+G L P P +P RTYYVRDNGLGIPA YL K+ Sbjct: 421 FSNLIGNALNFLDPARGGRIEVGALEPGPVDESEPRAVRMRTYYVRDNGLGIPAAYLSKV 480 Query: 475 FSAFHRLHADIAQGEGVGLALIKRIVLRHGGKIWVESTEGAGTTFYTSLPVRPIQ 529 F AF RLH D+A GEG+GLAL++R V RHGG++WVES EGAG+TF+ LP +P++ Sbjct: 481 FRAFQRLHGDVASGEGIGLALVRRTVERHGGRVWVESAEGAGSTFFVVLPEQPVR 535 >D5W6U4.1 D5W6U4_BURSC Multi-sensor signal transduction histidine kinase Length = 579 Score = 489 bits (1260), Expect = e-136, Method: Compositional matrix adjust. Identities = 257/525 (48%), Positives = 346/525 (65%) Query: 1 MKLFRKGLLLVAIPGIFELGLLGILYKSQENATQAEVLALHTKNVIIQAGEVREPVLLQS 60 M+L KGLLL+AIP +FEL LL + K+Q +AT AE A+H++ V+ QA + +PVL +S Sbjct: 1 MRLTTKGLLLIAIPAVFELALLTGVVKAQADATMAERRAIHSEEVLRQATAILDPVLSES 60 Query: 61 ARLRAAIILNDPAGLEKSDLWDSIEKELGELRELVGDNAEQLRRVAQIGASVQEYRQWTD 120 LR A++ ND +W +++ + EL +LVGDN Q+ RV ++ +VQ YRQW+D Sbjct: 61 VALRGAVLANDARFTTPIAVWMDVDRRIDELVDLVGDNPAQVERVVEVRQAVQAYRQWSD 120 Query: 121 LQTELLRNDKHDELVAALRDPNARRLIQVIQRQLVEFIKVEEELDQERLSSVVEARRMQN 180 +LL + EL+A D ++ + Q+ F E LD R ++V R + Sbjct: 121 RIEDLLHAGRRAELLACFHDRAQADVLDHFRLQVTAFQAEERRLDMSRSNAVAAVREREQ 180 Query: 181 IALVIALLGSVLAAALAARIFSHDVGGRLAVLTGNAHKLTEGGVLAQRVGGNDEITELDK 240 V A LGS+L ALA IF+ V GRLA+L+ NA +L LA G DEI LD Sbjct: 181 TLTVAAALGSLLFVALAIWIFTRGVRGRLALLSDNAGRLAGNEPLAPLGAGRDEIARLDL 240 Query: 241 VLHESSARLRQAEEDARVYREELERHAHELTSVNDDLQRQTQDNEMFIYSVSHDLRSPLV 300 LHE+S RL +AE +R +LER A EL +N+ L++QTQ+NEMFIYSVSHDLR+PLV Sbjct: 241 TLHETSRRLLEAERIEARFRADLERRAAELARINETLRQQTQENEMFIYSVSHDLRAPLV 300 Query: 301 NLQGFSKELHHSVGELHETIDASDLNDKDKQRIRDIIEDDVEVSLRFIRTAVTRSAAIID 360 NLQG SKEL + EL + + S L ++RI I+++D+ +L +++TAV R++ IID Sbjct: 301 NLQGVSKELIRACDELRDAVRGSSLAISSRERIERIVDEDIGEALHYLQTAVLRASHIID 360 Query: 361 AMLRLSRVGRVEYQSQETNVNEVVGRVIDAMSNTIRERQAVVVSQPLPPCYGDPTAVEQI 420 A+LRLSRVGRVEY+ Q+ +V ++V RV+DAM +IR R+A V LP +GDPTA+EQI Sbjct: 361 ALLRLSRVGRVEYRRQKVDVRDIVQRVVDAMQGSIRARRARVTVGELPAVWGDPTALEQI 420 Query: 421 FGNLIGNAVNYLNPKRAGTVEIGVLPPDPGQPDFRTYYVRDNGLGIPADYLGKMFSAFHR 480 F NLIGNAVNYL+P R G VEIG P PG R +YVRDNGLGIP+ L ++F+AF R Sbjct: 421 FANLIGNAVNYLDPAREGRVEIGTTPAPPGVHSLRIFYVRDNGLGIPSIALPRLFTAFQR 480 Query: 481 LHADIAQGEGVGLALIKRIVLRHGGKIWVESTEGAGTTFYTSLPV 525 LH A GEG+GLAL++R+V RHGG++W ES EG GTTFY SLPV Sbjct: 481 LHGHAAAGEGIGLALVRRMVERHGGRVWAESREGVGTTFYLSLPV 525 >Q140Y3.1 Q140Y3_BURXL Signal Transduction Histidine Kinases (STHK) Length = 591 Score = 489 bits (1259), Expect = e-136, Method: Compositional matrix adjust. Identities = 257/543 (47%), Positives = 354/543 (65%), Gaps = 5/543 (0%) Query: 1 MKLFRKGLLLVAIPGIFELGLLGILYKSQENATQAEVLALHTKNVIIQAGEVREPVLLQS 60 M+L KGLLL+AIP +FEL LL L K++ +A QAE A+H+++V+ Q + +PVL +S Sbjct: 1 MRLTTKGLLLIAIPAVFELALLSGLVKAESDAAQAERWAIHSQDVLRQTTAILDPVLGES 60 Query: 61 ARLRAAIILNDPAGLEKSDLWDSIEKELGELRELVGDNAEQLRRVAQIGASVQEYRQWTD 120 LR A++ ND +W +++ + +L +LV DN Q+ RV Q+ +VQ YRQW+D Sbjct: 61 VALRGAVLANDAHFATPVTVWMDVDRRIDQLADLVADNPAQVERVVQVRQAVQAYRQWSD 120 Query: 121 LQTELLRNDKHDELVAALRDPNARRLIQVIQRQLVEFIKVEEELDQERLSSVVEARRMQN 180 ++LR+ + +++A RD ++ ++QL F E LD R ++ AR Q Sbjct: 121 RVQDMLRSGRRRDVLARFRDLAPTDVLDRFRQQLAAFQAEERRLDTLRSNAADAARERQQ 180 Query: 181 IALVIALLGSVLAAALAARIFSHDVGGRLAVLTGNAHKLTEGGVLAQRVGGNDEITELDK 240 +V A+LGS+L ALA +F+ V GRLA+L NA +L LA G DEI LD Sbjct: 181 TLVVAAVLGSLLFVALAVWLFTRGVRGRLALLADNAGRLAGNEPLAPIGSGRDEIARLDL 240 Query: 241 VLHESSARLRQAEEDARVYREELERHAHELTSVNDDLQRQTQDNEMFIYSVSHDLRSPLV 300 LHE+S RL +AE ++ +L R EL +N+ L++QTQ+NEMFIYSVSHDLR+PLV Sbjct: 241 TLHETSRRLLEAERIQARFQADLARRTGELARINETLRQQTQENEMFIYSVSHDLRAPLV 300 Query: 301 NLQGFSKELHHSVGELHETIDASDLNDKDKQRIRDIIEDDVEVSLRFIRTAVTRSAAIID 360 NLQGFSKEL + EL + S L +QRI ++++D+ +L +++TAV R++ IID Sbjct: 301 NLQGFSKELIRACDELRVAVRESSLAAGTRQRIERVVDEDIGEALHYLQTAVLRASHIID 360 Query: 361 AMLRLSRVGRVEYQSQETNVNEVVGRVIDAMSNTIRERQAVVVSQPLPPCYGDPTAVEQI 420 A+LRLSRVGRVEY+ Q+ V ++V RVIDAM +IR R+A V LP +GDPTA+EQ+ Sbjct: 361 ALLRLSRVGRVEYRQQKVEVRDIVPRVIDAMQGSIRARRAHVHVDELPAVWGDPTALEQV 420 Query: 421 FGNLIGNAVNYLNPKRAGTVEIGVLPPDPGQPDFRTYYVRDNGLGIPADYLGKMFSAFHR 480 F NLIGNAVNYL+P R G +EIG P PG R +YVRDNGLGIPA L ++F+AF R Sbjct: 421 FANLIGNAVNYLDPSREGRIEIGTTPAPPGVHSLRIFYVRDNGLGIPAVALPRLFNAFQR 480 Query: 481 LHADIAQGEGVGLALIKRIVLRHGGKIWVESTEGAGTTFYTSLPVRPIQQVTPPATQLAQ 540 LH ++A GEG+GLAL++R+V RHGG++W ES EG GTTFY SLP + QLA Sbjct: 481 LHGNVAAGEGIGLALVRRVVERHGGRVWAESKEGVGTTFYLSLP-----EANARIAQLAA 535 Query: 541 GEQ 543 G Q Sbjct: 536 GTQ 538