BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0266.p (501 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1K8.1 D8J1K8_HERSS Phospholipase D family protein EC=2.7.8.- 680 0.0 D7DPZ6.1 D7DPZ6_METS0 Phospholipase D/Transphosphatidylase 605 e-171 Q223J7.1 Q223J7_RHOFD Cardiolipin synthetase 2 EC=2.7.8.- 526 e-147 Q47EA6.1 Q47EA6_DECAR Phospholipase D/Transphosphatidylase 491 e-136 E8WSC6.1 E8WSC6_GEOS8 Phospholipase D/Transphosphatidylase 490 e-136 >D8J1K8.1 D8J1K8_HERSS Phospholipase D family protein EC=2.7.8.- Length = 472 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/441 (74%), Positives = 378/441 (85%), Gaps = 3/441 (0%) Query: 64 PRIVPDMDTQSAKVIQIKGGRGILTPEQSKAVLDRFKDSNQDNLILEKHLAVEQAITGSP 123 P IVPDMDTQSA+ IQ+KGGRG+L+ QSKAVL++ + N DN +L++H+A+E AITGSP Sbjct: 32 PTIVPDMDTQSARTIQMKGGRGVLSEAQSKAVLEKLRAQNADNTLLDRHVAIEGAITGSP 91 Query: 124 LVAGNKVTLLIDGPATYASMFAAIREARDHVNMETYIFEDDEAGKQFADLLIDRQKHGVQ 183 LV GNKVTLLIDGPATYASM AI+ AR H+NMETYI EDDE G+QFADLLI Q GVQ Sbjct: 92 LVTGNKVTLLIDGPATYASMQQAIQAARYHINMETYIMEDDEVGRQFADLLIAMQNKGVQ 151 Query: 184 VNLMYDSVGTLSTPREFFQPMIDAGIQVLEFNPVNPAQARKGWEVNQRDHRKLLIVDGKT 243 VNLMYDSVG L+TPR FFQPMIDAGIQVLE+NP+NP Q RK WEVNQRDHRKLL+VDGKT Sbjct: 152 VNLMYDSVGALNTPRTFFQPMIDAGIQVLEYNPLNPTQLRKDWEVNQRDHRKLLVVDGKT 211 Query: 244 AFVGGINVSSVYSSGSF--RRSKPKDDDAG-KVPWRDTQVRMDGPVVAEFQKMFIDTWQK 300 AFVGGIN+SSVYSSGSF R+ KP+ + G ++PWRDTQVR+DGPV EFQK+F+DTW K Sbjct: 212 AFVGGINISSVYSSGSFSTRKKKPRVNAEGEQIPWRDTQVRIDGPVALEFQKLFVDTWNK 271 Query: 301 QHGPKLAEKNYYPKVDNKGPEIVRGIGSAPEDPYSVIYATFISAIQHAESKVYLTNAYFI 360 Q GP L + Y+P V G EIVR IGS+P+DPYSVIYATFISAIQHAE +YLTNAYF+ Sbjct: 272 QRGPALGDHRYFPTVAPAGNEIVRAIGSSPDDPYSVIYATFISAIQHAEKAIYLTNAYFV 331 Query: 361 PDPQLRDALKDAVKRGVDVRLVLPSKSDSKLVLYASRSFYTELLEGGVKIYERQDALLHS 420 PDPQLRD+LKDA +RGVDVRL+LPS SDS LVLYASRSFY ELLE G++IYERQDALLHS Sbjct: 332 PDPQLRDSLKDAARRGVDVRLILPSHSDSSLVLYASRSFYQELLEAGIRIYERQDALLHS 391 Query: 421 KTAMIDGVWSTIGSTNLDWRSFIYNQEINAVILGRQFGAQMQSMFERDMNASREITLEAW 480 KTA+IDGVWSTIGSTNLDWRSF+YNQEINAVIL QFG QM+SMF+RD+ AS+EIT E W Sbjct: 392 KTALIDGVWSTIGSTNLDWRSFVYNQEINAVILSPQFGVQMKSMFDRDLGASKEITKEQW 451 Query: 481 KDRPISDRMKEFGAGLWARWL 501 + RPIS+RMKEFGA +WAR L Sbjct: 452 EQRPISERMKEFGASVWARLL 472 >D7DPZ6.1 D7DPZ6_METS0 Phospholipase D/Transphosphatidylase Length = 464 Score = 605 bits (1561), Expect = e-171, Method: Compositional matrix adjust. Identities = 282/443 (63%), Positives = 350/443 (79%), Gaps = 3/443 (0%) Query: 59 GCSSLPRIVPDMDTQSAKVIQIKGGRGILTPEQSKAVLDRFKDSNQDNLILEKHLAVEQA 118 GC+S+P +VPDM Q A +++ G G L+ +QSKA++ + + + D I +KHLA+E Sbjct: 25 GCTSIPTMVPDMAMQQAHPVKLNGANGELSAKQSKAIIAKLQKNGDDTNIFDKHLALEAE 84 Query: 119 ITGSPLVAGNKVTLLIDGPATYASMFAAIREARDHVNMETYIFEDDEAGKQFADLLIDRQ 178 I GSPLV GNKV LLIDGP TY +MFAAI A+DH+NMET+I EDDE G++FA LI +Q Sbjct: 85 IVGSPLVVGNKVELLIDGPTTYDAMFAAIESAKDHINMETFIIEDDEIGQRFAKALIAKQ 144 Query: 179 KHGVQVNLMYDSVGTLSTPREFFQPMIDAGIQVLEFNPVNPAQARKGWEVNQRDHRKLLI 238 GVQVNL+YDSVG++STP FF + +GI VLE+NP+NP RKGW+VNQRDHRKLLI Sbjct: 145 ASGVQVNLIYDSVGSISTPTTFFDALKASGINVLEYNPINPLVTRKGWQVNQRDHRKLLI 204 Query: 239 VDGKTAFVGGINVSSVYSSGSFRRSKPKDDDAGKVPWRDTQVRMDGPVVAEFQKMFIDTW 298 VDG+ AFVGGIN+SSVYSSGSF RSK + K PWRDT +RM+GPVV+EFQK+F+ TW Sbjct: 205 VDGQIAFVGGINISSVYSSGSFGRSKTTKN---KQPWRDTHLRMEGPVVSEFQKLFMTTW 261 Query: 299 QKQHGPKLAEKNYYPKVDNKGPEIVRGIGSAPEDPYSVIYATFISAIQHAESKVYLTNAY 358 +Q G LA KNY+P KG E+VR IGS+P++PYS IY+T ISAI AE++V++TNAY Sbjct: 262 SQQKGQTLAVKNYFPDYPVKGSEVVRAIGSSPDEPYSQIYSTLISAINSAETQVFITNAY 321 Query: 359 FIPDPQLRDALKDAVKRGVDVRLVLPSKSDSKLVLYASRSFYTELLEGGVKIYERQDALL 418 F+PDP+L ALK+AV+RGVDVRL+LP K+DS +V YASRS+Y ELL VKIYERQDALL Sbjct: 322 FVPDPKLLTALKEAVQRGVDVRLLLPEKTDSTMVFYASRSYYDELLTANVKIYERQDALL 381 Query: 419 HSKTAMIDGVWSTIGSTNLDWRSFIYNQEINAVILGRQFGAQMQSMFERDMNASREITLE 478 H+KTAMIDGVWSTIGSTNLDWRSF NQEINAV+LG+ FG QMQSMFE+D+ +S ITLE Sbjct: 382 HAKTAMIDGVWSTIGSTNLDWRSFTNNQEINAVVLGQGFGTQMQSMFEKDLESSTLITLE 441 Query: 479 AWKDRPISDRMKEFGAGLWARWL 501 +W+ R I+ R+KE A LWAR+L Sbjct: 442 SWRSRSIAARIKERAARLWARFL 464 >Q223J7.1 Q223J7_RHOFD Cardiolipin synthetase 2 EC=2.7.8.- Length = 462 Score = 526 bits (1356), Expect = e-147, Method: Compositional matrix adjust. Identities = 252/463 (54%), Positives = 339/463 (73%), Gaps = 3/463 (0%) Query: 41 FTSRLLYTVAVTAV--IALAGCSSLPRIVPDMDTQSAKVIQIKGGRGILTPEQSKAVLDR 98 T L A TAV +A A C++LP + + + + + RG L ++S A+L + Sbjct: 1 MTLHTLLRSAATAVGALAFAACATLPDTDELIQRHAGQAARFETARGALPAQKSAAILAQ 60 Query: 99 FKDSNQDNLILEKHLAVEQAITGSPLVAGNKVTLLIDGPATYASMFAAIREARDHVNMET 158 K + D IL+K +A+EQA+ SPLV GNKVTLL DG ATY +MFAAIR ARDH+N+E+ Sbjct: 61 LKSQSGDIDILDKQIALEQAVNDSPLVLGNKVTLLQDGAATYPAMFAAIRSARDHINLES 120 Query: 159 YIFEDDEAGKQFADLLIDRQKHGVQVNLMYDSVGTLSTPREFFQPMIDAGIQVLEFNPVN 218 YI E+DE G+QF+DLL+ +Q GVQVN++YDSVG L+TP+ FF+ + GI+VLEFNP+N Sbjct: 121 YIIENDEVGRQFSDLLLAQQARGVQVNVIYDSVGALNTPKAFFERLKQGGIEVLEFNPIN 180 Query: 219 PAQARKGWEVNQRDHRKLLIVDGKTAFVGGINVSSVYSSGSFRRSKPKDDDAGKVPWRDT 278 P A+ W +N RDHRKLL+VDG+ AF+GGIN+SSVY SGS S+ A WRDT Sbjct: 181 PLTAKGPWMINHRDHRKLLLVDGRIAFIGGINISSVYGSGSIP-SRSHKAAANTDEWRDT 239 Query: 279 QVRMDGPVVAEFQKMFIDTWQKQHGPKLAEKNYYPKVDNKGPEIVRGIGSAPEDPYSVIY 338 ++++GPVV+EFQK+F+ TW+KQ G LA KNY+P + +G +IVR IGS P+DP+S++Y Sbjct: 240 DLQIEGPVVSEFQKLFLQTWEKQRGRPLATKNYFPALKVQGKDIVRTIGSTPDDPFSLMY 299 Query: 339 ATFISAIQHAESKVYLTNAYFIPDPQLRDALKDAVKRGVDVRLVLPSKSDSKLVLYASRS 398 T ISAI +AE +V+LT AYF+PDPQL AL A RGVDV+L+LPS SDS LV +A R+ Sbjct: 300 LTLISAIGNAEKQVHLTQAYFVPDPQLLQALVAAAGRGVDVKLILPSHSDSGLVFHAGRA 359 Query: 399 FYTELLEGGVKIYERQDALLHSKTAMIDGVWSTIGSTNLDWRSFIYNQEINAVILGRQFG 458 YTELL+GGVK+YER LLH+KTA+IDGVWST+GS+NLDWRSF+ N EI+AV+LG++F Sbjct: 360 HYTELLQGGVKLYERVGGLLHAKTAVIDGVWSTVGSSNLDWRSFLDNNEIDAVVLGQEFA 419 Query: 459 AQMQSMFERDMNASREITLEAWKDRPISDRMKEFGAGLWARWL 501 +M++MF D+ AS+ I L+ W+ RP+ R+KE+ A +W R L Sbjct: 420 QKMEAMFASDLQASQAIDLQGWQHRPLQFRIKEWLARVWERLL 462 >Q47EA6.1 Q47EA6_DECAR Phospholipase D/Transphosphatidylase Length = 475 Score = 491 bits (1264), Expect = e-136, Method: Compositional matrix adjust. Identities = 253/458 (55%), Positives = 334/458 (72%), Gaps = 2/458 (0%) Query: 44 RLLYTVAVTAVIALAGCSSLPRIVPDMDTQSAKVIQIKGGRGILTPEQSKAVLDRFKDSN 103 RL T A +A AGC+ LP + SA+ + + RG ++PE+S A++ K S Sbjct: 20 RLALTSAFLLFVA-AGCAMLPDTDAIIARHSAQTARFESARGTISPEKSAAIVASLKSSA 78 Query: 104 QDNLILEKHLAVEQAITGSPLVAGNKVTLLIDGPATYASMFAAIREARDHVNMETYIFED 163 D IL+K +A+EQAI GSPL+ GNKV LL DG ATYA+MFAAIR ARDH+N+E+YI ED Sbjct: 79 GDIDILDKQIALEQAIVGSPLIVGNKVILLQDGEATYAAMFAAIRAARDHINLESYIIED 138 Query: 164 DEAGKQFADLLIDRQKHGVQVNLMYDSVGTLSTPREFFQPMIDAGIQVLEFNPVNPAQAR 223 DE G+QFADLL+ +Q+ GVQVN++YDS G ++TP +F + GI V+EFNP+NP A+ Sbjct: 139 DEIGRQFADLLLAQQQQGVQVNVIYDSFGGMNTPAAYFDRLRQGGINVVEFNPINPLIAK 198 Query: 224 KGWEVNQRDHRKLLIVDGKTAFVGGINVSSVYSSGSFRRSKPKDDDAGKVPWRDTQVRMD 283 W N RDHRKLL+VDG+ AF+GGIN+S+VYSS R + K + WRDT ++++ Sbjct: 199 GQWLFNNRDHRKLLVVDGRIAFIGGINISNVYSSSPGSR-RAKKALGSAIDWRDTDLQIE 257 Query: 284 GPVVAEFQKMFIDTWQKQHGPKLAEKNYYPKVDNKGPEIVRGIGSAPEDPYSVIYATFIS 343 GPV E QK+F+DTW KQ G LA +NY+P++ +G +IVR IGS P+DPYS+IY T IS Sbjct: 258 GPVAGELQKLFMDTWSKQQGKPLAGRNYFPELKAQGKDIVRAIGSTPDDPYSLIYLTLIS 317 Query: 344 AIQHAESKVYLTNAYFIPDPQLRDALKDAVKRGVDVRLVLPSKSDSKLVLYASRSFYTEL 403 AI +AE +++LTNAYF+PDP+L AL DA RGVDV L+LPS++DSK+V +A RS Y+ L Sbjct: 318 AIGNAEREIHLTNAYFVPDPRLLKALSDAAGRGVDVNLILPSQTDSKIVFHAGRSHYSAL 377 Query: 404 LEGGVKIYERQDALLHSKTAMIDGVWSTIGSTNLDWRSFIYNQEINAVILGRQFGAQMQS 463 L+ GVKI+ER ALLHSKTA+IDGVWS +GSTNLDWRSF+ N E+NAVILGR FG QM++ Sbjct: 378 LKVGVKIHERGGALLHSKTALIDGVWSCVGSTNLDWRSFLDNDEVNAVILGRDFGLQMKA 437 Query: 464 MFERDMNASREITLEAWKDRPISDRMKEFGAGLWARWL 501 M RD+ AS+ I+ E W +R + R++E+GA L R L Sbjct: 438 MIARDLAASKAISAEDWANRSLLLRLQEWGASLLQRLL 475 >E8WSC6.1 E8WSC6_GEOS8 Phospholipase D/Transphosphatidylase Length = 462 Score = 490 bits (1262), Expect = e-136, Method: Compositional matrix adjust. Identities = 235/462 (50%), Positives = 332/462 (71%), Gaps = 17/462 (3%) Query: 45 LLYTVAVTAVIALAGCSSLP---RIVPDMDTQSAKVIQIKGGRGILTPEQSKAVLDRFKD 101 LL TV++ + GC+SLP RI+ D A+ QI RG ++P++SK +++R K Sbjct: 13 LLLTVSLDS-----GCASLPNVSRIIGDAPV--AQSPQIDSARGPVSPQKSKVIMERLKR 65 Query: 102 SNQDNLILEKHLAVEQAITGSPLVAGNKVTLLIDGPATYASMFAAIREARDHVNMETYIF 161 S +LE++ AV ++I+ SP+ GNKVTLL DG ATYA+MF A+R A+DH+N+E++I Sbjct: 66 SVAPTDLLERYSAVVESISDSPMTKGNKVTLLADGQATYAAMFKALRSAKDHINLESFII 125 Query: 162 EDDEAGKQFADLLIDRQKHGVQVNLMYDSVGTLSTPREFFQPMIDAGIQVLEFNPVNPAQ 221 EDDE G++FA LL+ +Q GV+V+L+YDSVG+LSTP FFQ + DAG+QV+EFNP+NP + Sbjct: 126 EDDETGRKFAALLLQKQAEGVRVHLIYDSVGSLSTPAAFFQRLSDAGVQVVEFNPINPLE 185 Query: 222 ARKGWEVNQRDHRKLLIVDGKTAFVGGINVSSVYSSGSFRRSKPKDDDAGKVP--WRDTQ 279 R+ W + RDHRK+LIVDG+ A +GG+N+S VYSSG RR K GK P WRDT Sbjct: 186 DREEWGLTHRDHRKILIVDGRVAIIGGVNISKVYSSGYRRRQK-----TGKAPIHWRDTD 240 Query: 280 VRMDGPVVAEFQKMFIDTWQKQHGPKLAEKNYYPKVDNKGPEIVRGIGSAPEDPYSVIYA 339 ++++GP VAE QK+F+DTW KQ GP L++ N++P + +G +VR +GS P + + + Sbjct: 241 LQIEGPSVAELQKLFLDTWLKQKGPALSKSNFFPDLKEQGNALVRVVGSTPGETNRIPFV 300 Query: 340 TFISAIQHAESKVYLTNAYFIPDPQLRDALKDAVKRGVDVRLVLPSKSDSKLVLYASRSF 399 ++SAI AE+ V+LTN+YFIPD Q+ +AL DA +RGVDV++VLPS +DSKL LYA R Sbjct: 301 VYVSAISFAENSVHLTNSYFIPDDQIEEALIDAARRGVDVKIVLPSVTDSKLALYAQRHH 360 Query: 400 YTELLEGGVKIYERQDALLHSKTAMIDGVWSTIGSTNLDWRSFIYNQEINAVILGRQFGA 459 Y++LL+ GVK+YE +LLH+KTA+IDGVWST+GSTNLD+ S + N E+NAVIL ++ Sbjct: 361 YSKLLKAGVKLYEHSSSLLHAKTAVIDGVWSTVGSTNLDYLSMLSNDEVNAVILNKELAL 420 Query: 460 QMQSMFERDMNASREITLEAWKDRPISDRMKEFGAGLWARWL 501 QM+ MF +D+ S++I LE W+ RP+ RM E+ L+ R L Sbjct: 421 QMEQMFTKDLADSKQILLEEWEKRPLIHRMGEWFINLFLRRL 462