BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0191.p (410 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXC9.1 D8IXC9_HERSS Acriflavin resistance lipoprotein A protein 588 e-166 A6T279.1 A6T279_JANMA Acriflavin resistance lipoprotein A 493 e-137 F1VXM2.1 F1VXM2_9BURK Putative acriflavin resistance lipoprotein a 481 e-133 A4G8J6.1 A4G8J6_HERAR Acriflavine resistance protein A 480 e-133 D8P1B4.1 D8P1B4_RALSO Component of acridine efflux pump, multidr... 452 e-125 >D8IXC9.1 D8IXC9_HERSS Acriflavin resistance lipoprotein A protein Length = 402 Score = 588 bits (1515), Expect = e-166, Method: Compositional matrix adjust. Identities = 301/412 (73%), Positives = 347/412 (84%), Gaps = 12/412 (2%) Query: 1 MSSVSRFTRLTLTVVAAAALAACGQKPNAQAGAGMPPGEVSVVTIAPERVTISNELPGRL 60 MSSVSRFTRLT+TV AAAL ACGQKP AQ G MPP EVSVVTIAP+RV I+NELPGR+ Sbjct: 1 MSSVSRFTRLTMTVAIAAALVACGQKPAAQGGP-MPPSEVSVVTIAPQRVAITNELPGRV 59 Query: 61 EATRVAEVRARVAGIILKRTFREGSEVKAGEVLYRIDPATFKANYDSALATLAKSQASLT 120 EA RVA+VRARVAGI+ KR F+EGSEVK G+VL++IDPA +KA+ +SA ATLA++QA+LT Sbjct: 60 EAFRVAQVRARVAGIVQKRVFKEGSEVKEGQVLFKIDPAQYKASLESAQATLARAQANLT 119 Query: 121 QASLKAQRYKPLVEVNAVSKQEYDDAVAAQKQAEADVAAGKAAVQTAGLSLGYATVTSPI 180 Q +L AQRYKPLVEVNAVSKQEYD+AVAAQKQAEADVAAGKAAVQTA L+LGYATVTSPI Sbjct: 120 QTTLTAQRYKPLVEVNAVSKQEYDNAVAAQKQAEADVAAGKAAVQTASLNLGYATVTSPI 179 Query: 181 SGRIGRALVTEGALVGQGDATQLAVVQQLDPIYVNLTQSSTDLLKLQQAMASGQLKTVGQ 240 SGRIGRALVTEGALVGQGDATQLA+VQQLDP+YVN+TQSS DLLKLQQAMA+GQLK+VG Sbjct: 180 SGRIGRALVTEGALVGQGDATQLALVQQLDPVYVNVTQSSADLLKLQQAMAAGQLKSVGD 239 Query: 241 GKAKVTLVTDDGRPYPLPGKLLFSDVTVDATTGAVTIRAEFPNPNRTLLPGMYVRAQLEQ 300 KA VTL ++G+ YPLPGKLLFSD++VD TG+V++RAEFPNP R LLPG YVRA++EQ Sbjct: 240 NKASVTLELENGQAYPLPGKLLFSDISVDENTGSVSLRAEFPNPKRLLLPGTYVRAKIEQ 299 Query: 301 AVNESAIVVPQQAVMRDLNGSSVFVVGDDNKVAARPVKTGSAQGNSWIVTDGLKAGDRVI 360 AV+E A++VPQQAV+RD GS+V VV +NKV RPVKTG A+GN+W V DGLK GDRVI Sbjct: 300 AVDEQALLVPQQAVVRDAGGSTVMVVNAENKVEPRPVKTGGARGNNWQVLDGLKEGDRVI 359 Query: 361 VEGIQKTKPGAPVKPVPWKGPAADAGAAPAGASAAPGRAPAKQDAAT--KAN 410 VEG+QK +PGA VKPV W PAGA A PAKQ+A+ KAN Sbjct: 360 VEGLQKVRPGATVKPVQWN---------PAGAPAQASGQPAKQEASAQPKAN 402 >A6T279.1 A6T279_JANMA Acriflavin resistance lipoprotein A Length = 422 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 247/378 (65%), Positives = 306/378 (80%), Gaps = 2/378 (0%) Query: 1 MSSVSRFTRLTLTVVAAAALAACGQKPNAQAGAGMPPGEVSVVTIAPERVTISNELPGRL 60 MSS+ R TRL+ + A+A CG K + A PP EVSVVT+ P + ++NELPGR+ Sbjct: 1 MSSLPRLTRLSAALFLIYAIAGCGAKSDQAAAP--PPQEVSVVTVQPGVLGVTNELPGRM 58 Query: 61 EATRVAEVRARVAGIILKRTFREGSEVKAGEVLYRIDPATFKANYDSALATLAKSQASLT 120 E+ RVAEVRARV GI+LKR FREGS+VKAG +LY+IDPA +A Y+SA A +A+ +A+L Sbjct: 59 ESIRVAEVRARVPGIVLKRVFREGSDVKAGTLLYQIDPAQLQATYNSADAAVARGEATLA 118 Query: 121 QASLKAQRYKPLVEVNAVSKQEYDDAVAAQKQAEADVAAGKAAVQTAGLSLGYATVTSPI 180 A KA+RYKPLVE NAVSKQEYDD AA+KQA AD+A+ KAA + A LSLGYA+VTSPI Sbjct: 119 TAEQKAKRYKPLVETNAVSKQEYDDVAAAEKQAIADLASAKAARENARLSLGYASVTSPI 178 Query: 181 SGRIGRALVTEGALVGQGDATQLAVVQQLDPIYVNLTQSSTDLLKLQQAMASGQLKTVGQ 240 SGRIGRALVTEGALVGQGD T LA+VQQ+DPIYVN+TQS+ ++LKL++AM G+LK+ G+ Sbjct: 179 SGRIGRALVTEGALVGQGDVTPLAIVQQIDPIYVNMTQSANEVLKLKRAMDEGKLKSAGK 238 Query: 241 GKAKVTLVTDDGRPYPLPGKLLFSDVTVDATTGAVTIRAEFPNPNRTLLPGMYVRAQLEQ 300 G AKVTLVTDDG+ Y GKLLFSD+TVD ++G+VT+RAE PNP+ LLPGMYVRA++EQ Sbjct: 239 GAAKVTLVTDDGQEYGRAGKLLFSDLTVDESSGSVTLRAEIPNPDGLLLPGMYVRARIEQ 298 Query: 301 AVNESAIVVPQQAVMRDLNGSSVFVVGDDNKVAARPVKTGSAQGNSWIVTDGLKAGDRVI 360 AV+E+AI VPQQAV+R GS+V VVG D KVA+RPV+TGS+ G +WI+TDGLK GD+VI Sbjct: 299 AVDENAITVPQQAVLRTPGGSAVMVVGADGKVASRPVQTGSSSGTAWIITDGLKEGDQVI 358 Query: 361 VEGIQKTKPGAPVKPVPW 378 VEG+QK +PGA VKPV W Sbjct: 359 VEGLQKVQPGATVKPVQW 376 >F1VXM2.1 F1VXM2_9BURK Putative acriflavin resistance lipoprotein a Length = 366 Score = 481 bits (1237), Expect = e-133, Method: Compositional matrix adjust. Identities = 229/340 (67%), Positives = 287/340 (84%) Query: 40 VSVVTIAPERVTISNELPGRLEATRVAEVRARVAGIILKRTFREGSEVKAGEVLYRIDPA 99 +++VT+ P + ++ ELPGR+EA+R+A+VRAR AGI+ KR FREGSEVKAG+VLYRIDPA Sbjct: 1 MAIVTVTPGSMPVTTELPGRIEASRIAQVRARAAGIVQKRVFREGSEVKAGDVLYRIDPA 60 Query: 100 TFKANYDSALATLAKSQASLTQASLKAQRYKPLVEVNAVSKQEYDDAVAAQKQAEADVAA 159 F+A YDSA A +AK+ A+L QA+LK QRY PLV+ NA+SKQEYDDAV A+ QA AD+AA Sbjct: 61 AFQAAYDSAQAVVAKADANLAQAALKVQRYAPLVKTNAISKQEYDDAVTAKTQASADLAA 120 Query: 160 GKAAVQTAGLSLGYATVTSPISGRIGRALVTEGALVGQGDATQLAVVQQLDPIYVNLTQS 219 GKAA Q A L+LGYATVT+PISGRIGRALVTEGALVG G+AT LA+VQQ+DP++VN+TQS Sbjct: 121 GKAARQVASLNLGYATVTAPISGRIGRALVTEGALVGLGEATPLAIVQQIDPVFVNMTQS 180 Query: 220 STDLLKLQQAMASGQLKTVGQGKAKVTLVTDDGRPYPLPGKLLFSDVTVDATTGAVTIRA 279 S ++L+LQ+AMASGQL++ G+G KVTLVT+DG+PY PGKLLFSD++VD ++GA+T+RA Sbjct: 181 SIEVLRLQRAMASGQLQSAGKGLVKVTLVTEDGKPYAHPGKLLFSDLSVDESSGAITLRA 240 Query: 280 EFPNPNRTLLPGMYVRAQLEQAVNESAIVVPQQAVMRDLNGSSVFVVGDDNKVAARPVKT 339 EFPNP R LLPGMYVRA+LEQA+NE+ I VPQQAV R ++V +V ++KV RP+KT Sbjct: 241 EFPNPERLLLPGMYVRAKLEQAINEATITVPQQAVQRTGQTATVLLVDAEDKVVVRPIKT 300 Query: 340 GSAQGNSWIVTDGLKAGDRVIVEGIQKTKPGAPVKPVPWK 379 ++QGN WIVTDGLKAGD+VIVEG QK KPGA VK + WK Sbjct: 301 STSQGNKWIVTDGLKAGDKVIVEGFQKVKPGATVKTILWK 340 >A4G8J6.1 A4G8J6_HERAR Acriflavine resistance protein A Length = 407 Score = 480 bits (1236), Expect = e-133, Method: Compositional matrix adjust. Identities = 243/379 (64%), Positives = 303/379 (79%), Gaps = 2/379 (0%) Query: 1 MSSVSRFTRLTLTVVAAAALAACGQKPNAQAGAGMPPGEVSVVTIAPERVTISNELPGRL 60 MSS+ R T L A+A CG+ A EVSVVTI + ++NELPGRL Sbjct: 1 MSSLPRLTSLGAAFFILFAVAGCGKSDAPAAAPPPT--EVSVVTIKSSALGVTNELPGRL 58 Query: 61 EATRVAEVRARVAGIILKRTFREGSEVKAGEVLYRIDPATFKANYDSALATLAKSQASLT 120 E+TR+AE+RARV G++LKRTFREGS+VKAG L+ IDPA FKA Y+SA A +A+++A+L Sbjct: 59 ESTRIAEIRARVPGVVLKRTFREGSDVKAGATLFLIDPAQFKATYNSANAAVARAEATLL 118 Query: 121 QASLKAQRYKPLVEVNAVSKQEYDDAVAAQKQAEADVAAGKAAVQTAGLSLGYATVTSPI 180 QA LK +RYKPLV NA+SKQEYDD A KQAEAD+AA KAA +TA LSL YATVTSPI Sbjct: 119 QAELKEKRYKPLVATNAISKQEYDDVTATLKQAEADLAASKAARETARLSLDYATVTSPI 178 Query: 181 SGRIGRALVTEGALVGQGDATQLAVVQQLDPIYVNLTQSSTDLLKLQQAMASGQLKTVGQ 240 SGRIGRALVTEGALVGQ +AT LA VQQ+DPIYVN+TQSST++L+LQ+A+A G+LK+ G+ Sbjct: 179 SGRIGRALVTEGALVGQNEATPLATVQQIDPIYVNMTQSSTEILQLQRALADGKLKSAGK 238 Query: 241 GKAKVTLVTDDGRPYPLPGKLLFSDVTVDATTGAVTIRAEFPNPNRTLLPGMYVRAQLEQ 300 G+ KVTLVT+DG+ Y PGKLLFSD+TVDA++GA+T+RAEFPNP+ LLPGMYVRA++EQ Sbjct: 239 GQVKVTLVTEDGQEYAQPGKLLFSDLTVDASSGAITLRAEFPNPDSQLLPGMYVRARVEQ 298 Query: 301 AVNESAIVVPQQAVMRDLNGSSVFVVGDDNKVAARPVKTGSAQGNSWIVTDGLKAGDRVI 360 A+NE+AI VPQQA+ R +G++V VV +N V +RPV TG+A G+SW+++DGLK GD+VI Sbjct: 299 AINENAITVPQQAISRTPDGAAVMVVSAENTVVSRPVTTGAASGDSWVISDGLKDGDQVI 358 Query: 361 VEGIQKTKPGAPVKPVPWK 379 VEG+QK KPGA VKPV WK Sbjct: 359 VEGLQKIKPGATVKPVQWK 377 >D8P1B4.1 D8P1B4_RALSO Component of acridine efflux pump, multidrug efflux system Length = 399 Score = 452 bits (1163), Expect = e-125, Method: Compositional matrix adjust. Identities = 250/398 (62%), Positives = 305/398 (76%), Gaps = 4/398 (1%) Query: 1 MSSVSRFTRLTLTVVAAAALAACGQKPNAQA--GAGMPPGEVSVVTIAPERVTISNELPG 58 M++ R+ +L ALAACG K AQ GAGMPP EV VVT+ P V ++ ELPG Sbjct: 1 MTNTRRYHQLAAAAFMIVALAACGNK-QAQGPGGAGMPPTEVGVVTVQPHAVGLTTELPG 59 Query: 59 RLEATRVAEVRARVAGIILKRTFREGSEVKAGEVLYRIDPATFKANYDSALATLAKSQAS 118 RLEATRVA+VRARVAGI+LKRT++EGS+VKAGEVL+RIDPA ++A+ DSA A LA+++A+ Sbjct: 60 RLEATRVAQVRARVAGIVLKRTYQEGSDVKAGEVLFRIDPAQYQASLDSAKAQLARAEAT 119 Query: 119 LTQASLKAQRYKPLVEVNAVSKQEYDDAVAAQKQAEADVAAGKAAVQTAGLSLGYATVTS 178 TQA LKA+RYKPLV NA+SKQ+YDDAVAA KQA ADV A +AAV TA L+LGYATVTS Sbjct: 120 QTQAQLKAERYKPLVATNAISKQDYDDAVAAAKQATADVGAARAAVDTAKLNLGYATVTS 179 Query: 179 PISGRIGRALVTEGALVGQ-GDATQLAVVQQLDPIYVNLTQSSTDLLKLQQAMASGQLKT 237 PISGR G A VTEGALVGQ GDAT LA VQQ+DPIY+ TQSST++++LQ+A+ +G+L Sbjct: 180 PISGRAGLAQVTEGALVGQGGDATLLATVQQIDPIYLTFTQSSTEVMRLQEALKAGKLAA 239 Query: 238 VGQGKAKVTLVTDDGRPYPLPGKLLFSDVTVDATTGAVTIRAEFPNPNRTLLPGMYVRAQ 297 AKVTLVT+DGR Y GKL FSD+TVD TTG++T+RA FPN RTLLPGMYVRA+ Sbjct: 240 ASDTAAKVTLVTEDGRVYAQTGKLYFSDLTVDQTTGSITLRAIFPNAERTLLPGMYVRAR 299 Query: 298 LEQAVNESAIVVPQQAVMRDLNGSSVFVVGDDNKVAARPVKTGSAQGNSWIVTDGLKAGD 357 LEQAV++ AI VPQQAV R +GS+V +V + KVA R V+ A G WIV GL+AGD Sbjct: 300 LEQAVDQQAITVPQQAVSRGADGSTVMIVDAEGKVAPRKVQADRAVGTEWIVASGLQAGD 359 Query: 358 RVIVEGIQKTKPGAPVKPVPWKGPAADAGAAPAGASAA 395 +VIV+G+QK +PGAPVKPV W+ A + A A A AA Sbjct: 360 KVIVDGLQKVRPGAPVKPVAWQAGGAPSQGATASAPAA 397