BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0147.p (295 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q2KC59.1 Q2KC59_RHIEC GDP-L-fucose synthase protein EC=1.1.1.271 439 e-121 B1Y4Q2.1 B1Y4Q2_LEPCP NAD-dependent epimerase/dehydratase 436 e-120 C6B1M8.1 C6B1M8_RHILS NAD-dependent epimerase/dehydratase 435 e-120 B1XZQ3.1 B1XZQ3_LEPCP NAD-dependent epimerase/dehydratase 434 e-120 Q1NXD9.1 Q1NXD9_9DELT NAD-dependent epimerase/dehydratase:dTDP-4... 426 e-117 >Q2KC59.1 Q2KC59_RHIEC GDP-L-fucose synthase protein EC=1.1.1.271 Length = 309 Score = 439 bits (1129), Expect = e-121, Method: Compositional matrix adjust. Identities = 198/292 (67%), Positives = 245/292 (83%) Query: 1 MVGSAITRRLQNDGYGNLVVRTHAELDLLDQARVREFLGREKPDYIFLAAAKVGGILANN 60 MVGSAI RRL + GY N++ RTHA+L+L+DQA FL EKPDYIF+AAAKVGGI ANN Sbjct: 15 MVGSAILRRLASAGYTNVITRTHADLNLVDQAATVRFLAEEKPDYIFMAAAKVGGIHANN 74 Query: 61 TYRADFIHQNLVMQSNVISGAHEAGVRRLMFLGSSCIYPRDCPQPIREEYLLTGPLEITN 120 TYRA+F++QNL++++N++ A +AGV+ ++FLGSSCIYPRDCPQPIRE+YLLTGPLE TN Sbjct: 75 TYRAEFLYQNLMIETNIVHAAWQAGVQGMLFLGSSCIYPRDCPQPIREDYLLTGPLEQTN 134 Query: 121 EPYAIAKIAGLKMCESYNRQYQTEYVTVMPTNLYGPNDNFDLATSHVLPALLRKAHEAKL 180 EPYAIAKIAG+K+CESYNRQY T+Y + MPTNLYGPND++DL SHVLPAL+RKAHEAK+ Sbjct: 135 EPYAIAKIAGVKLCESYNRQYGTQYASAMPTNLYGPNDSYDLNNSHVLPALIRKAHEAKI 194 Query: 181 GGEKRMVVWGSGKPMREFLYVDDMADACVFLMEQGVRNGAYNVGTGADVTIRDLARAILE 240 GEK +VVWGSG+PMREFLYVDDMADACVFLME + G +N+GTG DVTIR LA ++E Sbjct: 195 RGEKELVVWGSGQPMREFLYVDDMADACVFLMENQISEGLFNIGTGEDVTIRQLAETVME 254 Query: 241 TVGFDGELAFDASKPDGTPRKLLDVSLLASLGWRAKTMLDEGLIKTYQHYLS 292 VGF+G + +D SKPDGTPRKLL+V + +LGW+A+T L +G+ K Y + S Sbjct: 255 IVGFEGGIVYDISKPDGTPRKLLNVDRMKALGWQARTSLADGIAKAYADFRS 306 >B1Y4Q2.1 B1Y4Q2_LEPCP NAD-dependent epimerase/dehydratase Length = 312 Score = 436 bits (1121), Expect = e-120, Method: Compositional matrix adjust. Identities = 205/288 (71%), Positives = 237/288 (82%) Query: 1 MVGSAITRRLQNDGYGNLVVRTHAELDLLDQARVREFLGREKPDYIFLAAAKVGGILANN 60 MVGSAI RRLQ+ GY N++ RTHAELDLLDQ V FL +KPDYIF+AAAKVGGI ANN Sbjct: 15 MVGSAIVRRLQSLGYSNILTRTHAELDLLDQRAVHAFLAEQKPDYIFIAAAKVGGIQANN 74 Query: 61 TYRADFIHQNLVMQSNVISGAHEAGVRRLMFLGSSCIYPRDCPQPIREEYLLTGPLEITN 120 YRADF++QNL++++N+I GAH AGV+RLMFLGSSCIYPRDCPQPI+E+YLLTGPLE TN Sbjct: 75 LYRADFLYQNLLIEANLIHGAHLAGVQRLMFLGSSCIYPRDCPQPIKEDYLLTGPLEQTN 134 Query: 121 EPYAIAKIAGLKMCESYNRQYQTEYVTVMPTNLYGPNDNFDLATSHVLPALLRKAHEAKL 180 EPYAIAKIAG+K+ ESYNRQY +Y++ MPTNLYGPNDN+DLA SHVLPALLRKAHEAK Sbjct: 135 EPYAIAKIAGIKLAESYNRQYGRQYISAMPTNLYGPNDNYDLANSHVLPALLRKAHEAKQ 194 Query: 181 GGEKRMVVWGSGKPMREFLYVDDMADACVFLMEQGVRNGAYNVGTGADVTIRDLARAILE 240 G+ VVWGSG P REFLYVDD+ADACV LME G N+GTG DVTIR+LA +++ Sbjct: 195 RGDAEYVVWGSGTPKREFLYVDDLADACVHLMETGYDGPLVNIGTGEDVTIRELAETVMQ 254 Query: 241 TVGFDGELAFDASKPDGTPRKLLDVSLLASLGWRAKTMLDEGLIKTYQ 288 VGF+G + FDASKPDGTPRKLLDVS L SLGW A T L G+ Y+ Sbjct: 255 IVGFEGRIVFDASKPDGTPRKLLDVSRLKSLGWSASTSLRNGIRLAYE 302 >C6B1M8.1 C6B1M8_RHILS NAD-dependent epimerase/dehydratase Length = 306 Score = 435 bits (1119), Expect = e-120, Method: Compositional matrix adjust. Identities = 196/292 (67%), Positives = 245/292 (83%) Query: 1 MVGSAITRRLQNDGYGNLVVRTHAELDLLDQARVREFLGREKPDYIFLAAAKVGGILANN 60 MVGSAI RRL+ GY N+V R+HAELDL++QA V EF+ E+PDYIF+AAA+VGGI ANN Sbjct: 15 MVGSAIVRRLKAGGYTNIVTRSHAELDLVNQAAVAEFMKAERPDYIFMAAARVGGIHANN 74 Query: 61 TYRADFIHQNLVMQSNVISGAHEAGVRRLMFLGSSCIYPRDCPQPIREEYLLTGPLEITN 120 YRA+F++QNL++++NV+ A +AGV R++FLGSSCIYPRDCPQPIREEYLLTGPLE TN Sbjct: 75 VYRAEFLYQNLMIETNVVHAAWQAGVERMLFLGSSCIYPRDCPQPIREEYLLTGPLEQTN 134 Query: 121 EPYAIAKIAGLKMCESYNRQYQTEYVTVMPTNLYGPNDNFDLATSHVLPALLRKAHEAKL 180 E YAIAKIAG+K+CESYNRQY T YV+ MPTNLYGPNDN+DL +SHV+PAL+RK HEAK+ Sbjct: 135 EAYAIAKIAGVKLCESYNRQYGTRYVSGMPTNLYGPNDNYDLDSSHVMPALIRKVHEAKI 194 Query: 181 GGEKRMVVWGSGKPMREFLYVDDMADACVFLMEQGVRNGAYNVGTGADVTIRDLARAILE 240 G++++VVWGSG+PMREFLYVDDMADACVFLME+ V G N+GTG D+TIR+LA I+ Sbjct: 195 RGDRQLVVWGSGRPMREFLYVDDMADACVFLMEKEVSEGLINIGTGEDITIRELAETIMR 254 Query: 241 TVGFDGELAFDASKPDGTPRKLLDVSLLASLGWRAKTMLDEGLIKTYQHYLS 292 VGF GE+ +D +KPDGTPRKL+ V L++LGW+A T L +G+ + Y + S Sbjct: 255 VVGFTGEIVYDQTKPDGTPRKLMSVDRLSALGWKATTSLGDGIARAYADFAS 306 >B1XZQ3.1 B1XZQ3_LEPCP NAD-dependent epimerase/dehydratase Length = 308 Score = 434 bits (1116), Expect = e-120, Method: Compositional matrix adjust. Identities = 204/288 (70%), Positives = 239/288 (82%) Query: 1 MVGSAITRRLQNDGYGNLVVRTHAELDLLDQARVREFLGREKPDYIFLAAAKVGGILANN 60 MVGSAI RRLQ+ GY N++ RTHAELDLLDQ V FL EKPDYIF+AAAKVGGI ANN Sbjct: 15 MVGSAIVRRLQSLGYSNILTRTHAELDLLDQRAVHAFLADEKPDYIFIAAAKVGGIQANN 74 Query: 61 TYRADFIHQNLVMQSNVISGAHEAGVRRLMFLGSSCIYPRDCPQPIREEYLLTGPLEITN 120 YRADF++QNL++++N+I GAH AGV+RLMFLGSSCIYPRDCPQPI+E+YLLTGPLE TN Sbjct: 75 LYRADFLYQNLLIEANLIHGAHLAGVQRLMFLGSSCIYPRDCPQPIKEDYLLTGPLEQTN 134 Query: 121 EPYAIAKIAGLKMCESYNRQYQTEYVTVMPTNLYGPNDNFDLATSHVLPALLRKAHEAKL 180 EPYAIAKIAG+K+ ESYNRQY +Y++ MPTNLYGPNDN+DLA SHVLPALLRKAHEAK Sbjct: 135 EPYAIAKIAGIKLAESYNRQYGRQYISAMPTNLYGPNDNYDLANSHVLPALLRKAHEAKQ 194 Query: 181 GGEKRMVVWGSGKPMREFLYVDDMADACVFLMEQGVRNGAYNVGTGADVTIRDLARAILE 240 G+ VVWGSG P REFLYVDD+ADACV LM+ G N+GTG DVTIR+LA +++ Sbjct: 195 RGDAEYVVWGSGTPKREFLYVDDLADACVHLMQSGYDGPLVNIGTGEDVTIRELAETVMQ 254 Query: 241 TVGFDGELAFDASKPDGTPRKLLDVSLLASLGWRAKTMLDEGLIKTYQ 288 VGF+G + FDASKPDGTPRKLLDVS L LGW+A+T L +G+ Y+ Sbjct: 255 IVGFEGRIVFDASKPDGTPRKLLDVSRLKGLGWQARTGLRDGIRLAYE 302 >Q1NXD9.1 Q1NXD9_9DELT NAD-dependent epimerase/dehydratase:dTDP-4-dehydrorhamnose reductase Length = 312 Score = 426 bits (1095), Expect = e-117, Method: Compositional matrix adjust. Identities = 202/292 (69%), Positives = 238/292 (81%) Query: 1 MVGSAITRRLQNDGYGNLVVRTHAELDLLDQARVREFLGREKPDYIFLAAAKVGGILANN 60 MVG+A+ RRL+ GY NL+ R+ AELDLLDQA V +FLGREKPDYIFLAAA+VGGI ANN Sbjct: 20 MVGTALVRRLERGGYRNLLTRSRAELDLLDQAAVFDFLGREKPDYIFLAAARVGGIQANN 79 Query: 61 TYRADFIHQNLVMQSNVISGAHEAGVRRLMFLGSSCIYPRDCPQPIREEYLLTGPLEITN 120 T ADFI++NL +Q++VI GA AGV L FLGSSCIYPR+CPQPIREEYLLTGPLE TN Sbjct: 80 TRPADFIYENLAIQNHVIHGALRAGVSDLCFLGSSCIYPRECPQPIREEYLLTGPLEETN 139 Query: 121 EPYAIAKIAGLKMCESYNRQYQTEYVTVMPTNLYGPNDNFDLATSHVLPALLRKAHEAKL 180 PYA+AKIAG+K+C++ N+QY T YV VMPTNLYGPNDN+DL SHVLPAL+RKAHEA+ Sbjct: 140 APYAVAKIAGIKLCQACNQQYGTRYVAVMPTNLYGPNDNYDLEASHVLPALIRKAHEART 199 Query: 181 GGEKRMVVWGSGKPMREFLYVDDMADACVFLMEQGVRNGAYNVGTGADVTIRDLARAILE 240 G +VVWGSG P REFLYVDD+ADACVFLME+G+ +G YNVG G D+TIR+LA ++ Sbjct: 200 GELAELVVWGSGTPRREFLYVDDLADACVFLMERGIGHGLYNVGLGRDITIRELAETVMA 259 Query: 241 TVGFDGELAFDASKPDGTPRKLLDVSLLASLGWRAKTMLDEGLIKTYQHYLS 292 VGF G + FD SKPDGTPRKLLDVS L +LGWRA+T L EG+ Y YL+ Sbjct: 260 AVGFKGRIVFDRSKPDGTPRKLLDVSRLEALGWRAQTPLTEGIALAYADYLA 311