BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0144.p (272 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXC1.1 D8IXC1_HERSS Bis(5'-nucleosyl)-tetraphosphatase, symmet... 373 e-101 A6T287.1 APAH_JANMA Bis(5'-nucleosyl)-tetraphosphatase, symmetri... 362 4e-98 A4G8L5.1 APAH_HERAR Bis(5'-nucleosyl)-tetraphosphatase, symmetri... 354 1e-95 C3XAN9.1 C3XAN9_OXAFO Bis(5'-nucleosyl)-tetraphosphatase, symmet... 344 1e-92 C3X4I4.1 C3X4I4_OXAFO Bis(5'-nucleosyl)-tetraphosphatase, symmet... 343 2e-92 >D8IXC1.1 D8IXC1_HERSS Bis(5'-nucleosyl)-tetraphosphatase, symmetrical EC=3.6.1.41 Length = 274 Score = 373 bits (957), Expect = e-101, Method: Compositional matrix adjust. Identities = 181/269 (67%), Positives = 210/269 (78%), Gaps = 5/269 (1%) Query: 4 YAIGDLQGCNQQLQNLLDLIEKT--SPDAQLLFVGDLVNRGPQSLQTLRRLRELGSRAKA 61 Y IGDLQGC L LDL + S DAQL+F GDL+NRGPQSLQTLR + ++G RA+A Sbjct: 7 YVIGDLQGC---LTPFLDLQRQLPLSADAQLIFAGDLINRGPQSLQTLRTVMQMGQRAQA 63 Query: 62 VLGNHDLHLLAVSQGIRPQHRTDTLDDILNAPDRDELLDWLRHRPLALFEQGHLLFHAGL 121 VLGNHDLHLLAV+ GIRP HR DTL +IL APDR+EL+ WLRHRPLA+ Q HL+ HAG+ Sbjct: 64 VLGNHDLHLLAVACGIRPAHRDDTLAEILQAPDREELIHWLRHRPLAIHAQDHLIVHAGV 123 Query: 122 FPQWDAAKTMALAQEVEAMLRGPDWIDFLRHMYGNEPAVWSDELEGYDRLRCIINTLTRM 181 PQWD + +ALA EVE MLR WI FLRHMYGN+P WSD+L GYDRLRCIIN TR+ Sbjct: 124 LPQWDLQQALALAGEVETMLRSDQWIAFLRHMYGNQPDRWSDDLVGYDRLRCIINAFTRV 183 Query: 182 RFCTPDGAIDFKIKEGLGAAPDGYLPWFDMPGRQTAGVTCVFGHWASLGLTRRPNLIGLD 241 RFC DG +DF +KEG AAP G PWFD+PGR+T VT VFGHW++LGL RPNLI LD Sbjct: 184 RFCQADGTMDFAVKEGAAAAPAGLTPWFDVPGRRTEEVTVVFGHWSTLGLVMRPNLIALD 243 Query: 242 TGCVWGGKLTAVRLEDRALFQVDCPRAEQ 270 TGCVWGG+L+AVRLEDRALFQV CP+A + Sbjct: 244 TGCVWGGQLSAVRLEDRALFQVQCPQARR 272 >A6T287.1 APAH_JANMA Bis(5'-nucleosyl)-tetraphosphatase, symmetrical EC=3.6.1.41 Length = 274 Score = 362 bits (928), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 166/270 (61%), Positives = 210/270 (77%) Query: 1 MPTYAIGDLQGCNQQLQNLLDLIEKTSPDAQLLFVGDLVNRGPQSLQTLRRLRELGSRAK 60 M TYAIGDLQGC QL +LL I+ +P AQL+FVGD+VNRGP+SL TLR++R LG RA+ Sbjct: 1 MTTYAIGDLQGCQTQLNDLLQKIDAVAPQAQLVFVGDIVNRGPRSLATLRQVRALGQRAR 60 Query: 61 AVLGNHDLHLLAVSQGIRPQHRTDTLDDILNAPDRDELLDWLRHRPLALFEQGHLLFHAG 120 VLGNHDL+LLA++ G+R H +DT+DDI+ A DRDEL+DWLRH+PLAL HL HAG Sbjct: 61 IVLGNHDLNLLAIACGLRKPHASDTVDDIMAADDRDELIDWLRHQPLALARDNHLFVHAG 120 Query: 121 LFPQWDAAKTMALAQEVEAMLRGPDWIDFLRHMYGNEPAVWSDELEGYDRLRCIINTLTR 180 + PQW AA+T+AL++EVEA+L+GPDW+ FL+ MYGNEP++W D L+G DRLRCI+N LTR Sbjct: 121 VLPQWSAAQTVALSREVEAVLQGPDWVAFLQKMYGNEPSLWDDSLQGDDRLRCIVNALTR 180 Query: 181 MRFCTPDGAIDFKIKEGLGAAPDGYLPWFDMPGRQTAGVTCVFGHWASLGLTRRPNLIGL 240 +RFC DG +DFK E L P G +PWFD P R++ T VFGHW++LGL PN+IGL Sbjct: 181 IRFCQADGRMDFKAVESLAHTPAGLMPWFDAPDRRSTDTTVVFGHWSTLGLMVLPNVIGL 240 Query: 241 DTGCVWGGKLTAVRLEDRALFQVDCPRAEQ 270 DTGCVWGG+LTA+ L DR QV CP+ ++ Sbjct: 241 DTGCVWGGQLTAMNLTDRTTIQVKCPQHQK 270 >A4G8L5.1 APAH_HERAR Bis(5'-nucleosyl)-tetraphosphatase, symmetrical EC=3.6.1.41 Length = 275 Score = 354 bits (908), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 170/270 (62%), Positives = 206/270 (76%) Query: 1 MPTYAIGDLQGCNQQLQNLLDLIEKTSPDAQLLFVGDLVNRGPQSLQTLRRLRELGSRAK 60 M TYAIGDLQGC+ QL LLD I+ +P AQL+FVGD+VNRGP+SL TLR L L RA+ Sbjct: 1 MTTYAIGDLQGCHTQLLALLDKIDAITPQAQLVFVGDIVNRGPKSLATLRHLYGLRQRAR 60 Query: 61 AVLGNHDLHLLAVSQGIRPQHRTDTLDDILNAPDRDELLDWLRHRPLALFEQGHLLFHAG 120 VLGNHDL+LLAV+ G+R H DTLDDIL A DR+ELL WLRH+PLAL + GHL HAG Sbjct: 61 IVLGNHDLNLLAVACGLRKPHHADTLDDILAAHDREELLTWLRHQPLALEQDGHLCVHAG 120 Query: 121 LFPQWDAAKTMALAQEVEAMLRGPDWIDFLRHMYGNEPAVWSDELEGYDRLRCIINTLTR 180 + PQW + +AL+ EVEA+L+ +W+ FL MYGNEPA W D+L+G DRLRCI+N LTR Sbjct: 121 VLPQWSMQQALALSGEVEAVLQSENWVAFLHGMYGNEPARWDDDLQGADRLRCIVNALTR 180 Query: 181 MRFCTPDGAIDFKIKEGLGAAPDGYLPWFDMPGRQTAGVTCVFGHWASLGLTRRPNLIGL 240 +RFC+PDG +DFK E P G LPWFD+P R+TA T VFGHW++LGL RPNL+GL Sbjct: 181 LRFCSPDGRMDFKTTEAAENPPAGLLPWFDLPDRKTADSTVVFGHWSTLGLLMRPNLLGL 240 Query: 241 DTGCVWGGKLTAVRLEDRALFQVDCPRAEQ 270 DTGCVWGGKLTAV L+DR QV CP+ ++ Sbjct: 241 DTGCVWGGKLTAVNLQDRTTIQVACPQHQR 270 >C3XAN9.1 C3XAN9_OXAFO Bis(5'-nucleosyl)-tetraphosphatase, symmetrical EC=3.6.1.41 Length = 277 Score = 344 bits (882), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 163/266 (61%), Positives = 199/266 (74%) Query: 1 MPTYAIGDLQGCNQQLQNLLDLIEKTSPDAQLLFVGDLVNRGPQSLQTLRRLRELGSRAK 60 M +YA+GD+QGC Q+Q LL++IE+ SP A+LLF GDLVNRGP SL LR+++ L +A Sbjct: 1 MTSYALGDIQGCQPQMQELLEMIERESPYAKLLFAGDLVNRGPNSLDALRQVKNLEEKAV 60 Query: 61 AVLGNHDLHLLAVSQGIRPQHRTDTLDDILNAPDRDELLDWLRHRPLALFEQGHLLFHAG 120 VLGNHDLHLLAV+ GI D++ IL+APDRDEL+DWLRHRP+A + +LL HAG Sbjct: 61 TVLGNHDLHLLAVAAGIGQIKPGDSIQPILDAPDRDELIDWLRHRPMAYTDDDYLLVHAG 120 Query: 121 LFPQWDAAKTMALAQEVEAMLRGPDWIDFLRHMYGNEPAVWSDELEGYDRLRCIINTLTR 180 + PQWD KTM LA EVE +LRG DW FL+ MYGN P W D L G RLRCI+N LTR Sbjct: 121 VLPQWDLNKTMELAHEVEMVLRGSDWKAFLKEMYGNVPNQWDDGLTGTARLRCIVNGLTR 180 Query: 181 MRFCTPDGAIDFKIKEGLGAAPDGYLPWFDMPGRQTAGVTCVFGHWASLGLTRRPNLIGL 240 +RFC DG ++F K G AP GY+PWFD+P R+T VT VFGHW++LGL R NLI L Sbjct: 181 LRFCKADGEMEFASKMGTSEAPAGYMPWFDVPDRKTKDVTLVFGHWSTLGLLLRDNLIAL 240 Query: 241 DTGCVWGGKLTAVRLEDRALFQVDCP 266 DTGCVWGG+LTAVRL+DR++FQV CP Sbjct: 241 DTGCVWGGQLTAVRLDDRSVFQVACP 266 >C3X4I4.1 C3X4I4_OXAFO Bis(5'-nucleosyl)-tetraphosphatase, symmetrical EC=3.6.1.41 Length = 280 Score = 343 bits (880), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 169/266 (63%), Positives = 203/266 (76%) Query: 1 MPTYAIGDLQGCNQQLQNLLDLIEKTSPDAQLLFVGDLVNRGPQSLQTLRRLRELGSRAK 60 M TYA+GD+QGC QL+ LL++IE+ +P A+LLF GDLVNRGP+SL+ LR++R+L RA Sbjct: 1 MTTYALGDIQGCQPQLRELLEIIEEETPGAKLLFAGDLVNRGPRSLEALRQVRDLDDRAV 60 Query: 61 AVLGNHDLHLLAVSQGIRPQHRTDTLDDILNAPDRDELLDWLRHRPLALFEQGHLLFHAG 120 VLGNHDLHLLAV+ GI+ D++ +L+APDR+EL+DWLRHRP+A G LL HAG Sbjct: 61 TVLGNHDLHLLAVAAGIQKMKPGDSIQPVLDAPDREELIDWLRHRPMAYTGDGLLLVHAG 120 Query: 121 LFPQWDAAKTMALAQEVEAMLRGPDWIDFLRHMYGNEPAVWSDELEGYDRLRCIINTLTR 180 + PQWD KTM LA EVE +LR DW DFL MYGN P W D L G RLRCI+N LTR Sbjct: 121 VLPQWDLTKTMELAHEVEHVLRSADWKDFLAEMYGNSPNQWRDSLTGTARLRCIVNGLTR 180 Query: 181 MRFCTPDGAIDFKIKEGLGAAPDGYLPWFDMPGRQTAGVTCVFGHWASLGLTRRPNLIGL 240 +RFCT +G ++F K G AP GYLPWFD+PGR+T T VFGHW++LGL R NL+ L Sbjct: 181 LRFCTEEGEMEFASKMGTNEAPAGYLPWFDVPGRKTEKDTVVFGHWSTLGLLLRDNLVAL 240 Query: 241 DTGCVWGGKLTAVRLEDRALFQVDCP 266 DTGCVWGGKLTAVRLEDRALFQVDCP Sbjct: 241 DTGCVWGGKLTAVRLEDRALFQVDCP 266