BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0129.p (574 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4G1W0.2 A4G1W0_HERAR DNA polymerase I (POL I) EC=2.7.7.7 1020 0.0 A6SUR6.1 A6SUR6_JANMA DNA polymerase I EC=2.7.7.7 1018 0.0 F1W332.1 F1W332_9BURK DNA polymerase I 1010 0.0 D8IXA4.1 D8IXA4_HERSS DNA polymerase I protein EC=2.7.7.7 1004 0.0 Q0K851.1 Q0K851_CUPNH DNA polymerase I EC=2.7.7.7 890 0.0 >A4G1W0.2 A4G1W0_HERAR DNA polymerase I (POL I) EC=2.7.7.7 Length = 917 Score = 1020 bits (2638), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/574 (83%), Positives = 530/574 (92%) Query: 1 VDTETTSLVPMQAQLVGISLCCEAGRAAYIPVAHNYQDMPAQLPRELVLAKLKPWLEDDS 60 +DTETTSL PMQAQLVGISLCCE G AAYIPVAH YQD+P QL R VL KL+ WLEDDS Sbjct: 344 IDTETTSLEPMQAQLVGISLCCEPGVAAYIPVAHRYQDVPLQLSRASVLEKLRSWLEDDS 403 Query: 61 KPKLGQNLKYDSHIFANQGIQLRGIVHDTLLESYVFESHRTHDMDSLALRHLNRTTISYT 120 KPK+GQNLKYDSHIFAN G+ LRGIVHDTLL+SYVFESHR+HDMDSLALRHLNR T+++ Sbjct: 404 KPKVGQNLKYDSHIFANHGVTLRGIVHDTLLQSYVFESHRSHDMDSLALRHLNRKTMTFQ 463 Query: 121 DVCGKGASQICFDQVEIGRATEYAAEDADVTLALHQAMWPQVENDAKLRYIYEKIEVPTS 180 DVCGKGASQ+CFDQV+I RATEYAAEDAD+TL LHQ M+P V DA L ++YEKIE+PT+ Sbjct: 464 DVCGKGASQLCFDQVDIARATEYAAEDADITLQLHQRMFPHVAEDAGLSFVYEKIELPTA 523 Query: 181 VVLQKIERNGVLVDAAILATQSNELGKRMLEIEQQAYELAGQPFNLNSPKQLGEILFEKL 240 VVLQK+ERNGVL+D +LATQS+ELGKRMLEIEQQAYELAGQPFNL SPKQ+GEI FEK+ Sbjct: 524 VVLQKVERNGVLIDPGLLATQSHELGKRMLEIEQQAYELAGQPFNLGSPKQIGEIFFEKM 583 Query: 241 QLPVVKKTPSGTPSTDEEVLAKLAEDYPLPKILLDYRGLSKLKSTYTDKLPKMVDPTTGR 300 +LPVVKKTPSG+PSTDEEVL KLAEDYPLPK+LL+YRGLSKLKSTYTDKLPKM+DP TGR Sbjct: 584 KLPVVKKTPSGSPSTDEEVLQKLAEDYPLPKLLLEYRGLSKLKSTYTDKLPKMIDPATGR 643 Query: 301 VHTNYAQAVAVTGRLASNDPNLQNIPIRTAEGRRIREAFIAPPGSTIVSADYSQIELRIM 360 VHTNYAQAVAVTGRL+SNDPNLQNIPIR AEGRRIREAFIAPPGS IVSADYSQIELRIM Sbjct: 644 VHTNYAQAVAVTGRLSSNDPNLQNIPIRNAEGRRIREAFIAPPGSVIVSADYSQIELRIM 703 Query: 361 AHISGDANMLKAFADGEDIHRATASEIFGVGLADVTSEQRRYAKVINFGLIYGMSAFGLA 420 AHIS D NML+AFA+GEDIHRATA+EIFGV DV+SEQRRYAKVINFGLIYGMSAFGLA Sbjct: 704 AHISEDENMLRAFAEGEDIHRATAAEIFGVARGDVSSEQRRYAKVINFGLIYGMSAFGLA 763 Query: 421 GNLGIERSAAQMYIDKYFQRFSSVKQYMDDTRLEAKSQGYVETVFGRRLWLPEINSPNGP 480 GNLGIER+AAQ YI+KYF RFS VK+YMDDTRLEAK++GYV+TVFGRRLWLPEINSPNGP Sbjct: 764 GNLGIERAAAQSYIEKYFYRFSGVKRYMDDTRLEAKARGYVQTVFGRRLWLPEINSPNGP 823 Query: 481 RRQGAERAAINAPMQGTAADLIKLAMISVQGWIEQDGLQSKLIMQVHDELVMEVPDAELA 540 RRQGAERAAINAPMQGTAADLIKLAMI+VQ W+E + LQ+K+IMQVHDELV+EVP+ ELA Sbjct: 824 RRQGAERAAINAPMQGTAADLIKLAMIAVQDWLEAEKLQTKMIMQVHDELVLEVPETELA 883 Query: 541 LVREKLPELMKNVAELKVPLIAEVGAGKNWDQAH 574 LVR KLPELM+NVA+LKVPLIAEVG GKNWD+AH Sbjct: 884 LVRVKLPELMRNVAQLKVPLIAEVGVGKNWDEAH 917 >A6SUR6.1 A6SUR6_JANMA DNA polymerase I EC=2.7.7.7 Length = 912 Score = 1018 bits (2633), Expect = 0.0, Method: Compositional matrix adjust. Identities = 483/574 (84%), Positives = 529/574 (92%) Query: 1 VDTETTSLVPMQAQLVGISLCCEAGRAAYIPVAHNYQDMPAQLPRELVLAKLKPWLEDDS 60 +DTETTSL+PMQAQLVGISLCCE G AAYIPVAH+YQD+P QL RELVL K+KPWLED S Sbjct: 339 IDTETTSLIPMQAQLVGISLCCEPGVAAYIPVAHHYQDVPQQLSRELVLEKMKPWLEDAS 398 Query: 61 KPKLGQNLKYDSHIFANQGIQLRGIVHDTLLESYVFESHRTHDMDSLALRHLNRTTISYT 120 K K+GQNLKYDSHIFAN G+ LRGIVHDTLLESYVFESHR+HDMDSLALRHLNR TI++ Sbjct: 399 KAKVGQNLKYDSHIFANHGVNLRGIVHDTLLESYVFESHRSHDMDSLALRHLNRKTITFQ 458 Query: 121 DVCGKGASQICFDQVEIGRATEYAAEDADVTLALHQAMWPQVENDAKLRYIYEKIEVPTS 180 +VCGKGASQI F+QVEIGRATEYAAEDAD+TL LHQ MWP V D L ++YEKIE+PT+ Sbjct: 459 EVCGKGASQIGFEQVEIGRATEYAAEDADITLQLHQRMWPNVAEDNGLTFVYEKIELPTA 518 Query: 181 VVLQKIERNGVLVDAAILATQSNELGKRMLEIEQQAYELAGQPFNLNSPKQLGEILFEKL 240 VVLQKIERNGVL+D +LA QSNELGKRMLEIEQ AYELA QPFNLNSPKQ+GEI FEKL Sbjct: 519 VVLQKIERNGVLIDPDLLAKQSNELGKRMLEIEQNAYELAEQPFNLNSPKQIGEIFFEKL 578 Query: 241 QLPVVKKTPSGTPSTDEEVLAKLAEDYPLPKILLDYRGLSKLKSTYTDKLPKMVDPTTGR 300 +LPVVKKTPSG+PSTDEEVL KLAEDYPLPK+LL+YRGLSKLKSTYTDKLPKM+DPTTGR Sbjct: 579 KLPVVKKTPSGSPSTDEEVLQKLAEDYPLPKVLLEYRGLSKLKSTYTDKLPKMIDPTTGR 638 Query: 301 VHTNYAQAVAVTGRLASNDPNLQNIPIRTAEGRRIREAFIAPPGSTIVSADYSQIELRIM 360 VHTNYAQAVAVTGRLASNDPNLQNIPIR AEGRRIREAFIA PG+ IVSADYSQIELRIM Sbjct: 639 VHTNYAQAVAVTGRLASNDPNLQNIPIRNAEGRRIREAFIAAPGNVIVSADYSQIELRIM 698 Query: 361 AHISGDANMLKAFADGEDIHRATASEIFGVGLADVTSEQRRYAKVINFGLIYGMSAFGLA 420 AHISGD NML+AFADGEDIHRATA+EIFGV V SEQRRYAKVINFGLIYGMSAFGLA Sbjct: 699 AHISGDENMLQAFADGEDIHRATAAEIFGVERRAVDSEQRRYAKVINFGLIYGMSAFGLA 758 Query: 421 GNLGIERSAAQMYIDKYFQRFSSVKQYMDDTRLEAKSQGYVETVFGRRLWLPEINSPNGP 480 GNLGIERSAAQ YI++YF RF+ VK+YMD+TRLEAK++GYV+TVFGRRLWLPEINSPNGP Sbjct: 759 GNLGIERSAAQSYIERYFHRFAGVKRYMDETRLEAKARGYVQTVFGRRLWLPEINSPNGP 818 Query: 481 RRQGAERAAINAPMQGTAADLIKLAMISVQGWIEQDGLQSKLIMQVHDELVMEVPDAELA 540 RRQGAERAAINAPMQGTAADLIKLAMI+VQGW+E + LQSK+IMQVHDELV+EVP+ EL Sbjct: 819 RRQGAERAAINAPMQGTAADLIKLAMIAVQGWLETEKLQSKMIMQVHDELVLEVPETELP 878 Query: 541 LVREKLPELMKNVAELKVPLIAEVGAGKNWDQAH 574 LVREKLPELM++VA+LKVPLIAEVG G NWD+AH Sbjct: 879 LVREKLPELMRHVAQLKVPLIAEVGVGNNWDKAH 912 >F1W332.1 F1W332_9BURK DNA polymerase I Length = 914 Score = 1010 bits (2612), Expect = 0.0, Method: Compositional matrix adjust. Identities = 477/574 (83%), Positives = 519/574 (90%) Query: 1 VDTETTSLVPMQAQLVGISLCCEAGRAAYIPVAHNYQDMPAQLPRELVLAKLKPWLEDDS 60 +DTETTSLVP+QAQLVGISLCCE G AAYIPVAH Y D P QL RELVL K++ WLED + Sbjct: 341 IDTETTSLVPLQAQLVGISLCCEPGVAAYIPVAHRYADAPVQLSRELVLGKMQAWLEDPA 400 Query: 61 KPKLGQNLKYDSHIFANQGIQLRGIVHDTLLESYVFESHRTHDMDSLALRHLNRTTISYT 120 K K+GQNLKYDSHIFAN GI LRGI HDT+LESYVFESHR+HDMDSLALRHL RTTI++ Sbjct: 401 KAKVGQNLKYDSHIFANHGITLRGIAHDTMLESYVFESHRSHDMDSLALRHLGRTTITFQ 460 Query: 121 DVCGKGASQICFDQVEIGRATEYAAEDADVTLALHQAMWPQVENDAKLRYIYEKIEVPTS 180 +VCGKGASQICFDQV+I RATEYAAEDAD+TL LHQAM PQV +D L ++YEKIEVPT+ Sbjct: 461 EVCGKGASQICFDQVDIARATEYAAEDADITLQLHQAMLPQVTSDEGLLFVYEKIEVPTA 520 Query: 181 VVLQKIERNGVLVDAAILATQSNELGKRMLEIEQQAYELAGQPFNLNSPKQLGEILFEKL 240 VVLQKIERNGVL+D IL QS+ELGKRMLEIE AYELAGQPFNLNSPKQ+GEI FEKL Sbjct: 521 VVLQKIERNGVLIDTGILQVQSHELGKRMLEIETSAYELAGQPFNLNSPKQIGEIFFEKL 580 Query: 241 QLPVVKKTPSGTPSTDEEVLAKLAEDYPLPKILLDYRGLSKLKSTYTDKLPKMVDPTTGR 300 QLPVVKKTPSG PSTDEEVLAKLAEDYPLPK+LL+YR LSKLKSTYTDKLPKM+DPTTGR Sbjct: 581 QLPVVKKTPSGAPSTDEEVLAKLAEDYPLPKVLLEYRSLSKLKSTYTDKLPKMIDPTTGR 640 Query: 301 VHTNYAQAVAVTGRLASNDPNLQNIPIRTAEGRRIREAFIAPPGSTIVSADYSQIELRIM 360 VHTNYAQ VAVTGRLASN+PNLQNIPIRTAEGRRIREAF+AP GS IVSADYSQIELRIM Sbjct: 641 VHTNYAQTVAVTGRLASNEPNLQNIPIRTAEGRRIREAFVAPAGSVIVSADYSQIELRIM 700 Query: 361 AHISGDANMLKAFADGEDIHRATASEIFGVGLADVTSEQRRYAKVINFGLIYGMSAFGLA 420 AH+SGDANML+AFADG DIHRATA+EIF G ADVT+EQRRYAKVINFGLIYGMSAFGLA Sbjct: 701 AHLSGDANMLRAFADGIDIHRATAAEIFSTGAADVTTEQRRYAKVINFGLIYGMSAFGLA 760 Query: 421 GNLGIERSAAQMYIDKYFQRFSSVKQYMDDTRLEAKSQGYVETVFGRRLWLPEINSPNGP 480 GNLGIER AAQ YIDKYF RFS VKQ+MD+TRL+AK+ GYVETVFGRRLWLPEINSPNGP Sbjct: 761 GNLGIERGAAQSYIDKYFARFSGVKQFMDETRLKAKAHGYVETVFGRRLWLPEINSPNGP 820 Query: 481 RRQGAERAAINAPMQGTAADLIKLAMISVQGWIEQDGLQSKLIMQVHDELVMEVPDAELA 540 RRQGAERAAINAPMQGTAADLIKL+M++VQGW+E DGL+S ++MQVHDELV+EVP EL Sbjct: 821 RRQGAERAAINAPMQGTAADLIKLSMVAVQGWLETDGLKSLMVMQVHDELVLEVPQEELE 880 Query: 541 LVREKLPELMKNVAELKVPLIAEVGAGKNWDQAH 574 LVR KLP LM VAELKVPL AEVG GKNWD+AH Sbjct: 881 LVRVKLPALMAGVAELKVPLTAEVGIGKNWDEAH 914 >D8IXA4.1 D8IXA4_HERSS DNA polymerase I protein EC=2.7.7.7 Length = 920 Score = 1004 bits (2596), Expect = 0.0, Method: Compositional matrix adjust. Identities = 479/574 (83%), Positives = 524/574 (91%) Query: 1 VDTETTSLVPMQAQLVGISLCCEAGRAAYIPVAHNYQDMPAQLPRELVLAKLKPWLEDDS 60 VDTETTSL MQA+LVGISLCCE GRAAYIPVAHNYQD P QL R+ VL KLKPWLED S Sbjct: 347 VDTETTSLEAMQAELVGISLCCEPGRAAYIPVAHNYQDAPVQLSRQHVLEKLKPWLEDAS 406 Query: 61 KPKLGQNLKYDSHIFANQGIQLRGIVHDTLLESYVFESHRTHDMDSLALRHLNRTTISYT 120 KPKLGQ+LKYDSHIFAN G++L G+ HDTLLESYVFESHR HDMDSLA RHL R TI+Y Sbjct: 407 KPKLGQHLKYDSHIFANYGVRLAGVKHDTLLESYVFESHRPHDMDSLAARHLERKTITYA 466 Query: 121 DVCGKGASQICFDQVEIGRATEYAAEDADVTLALHQAMWPQVENDAKLRYIYEKIEVPTS 180 +VCGKGASQI F++V I RATEYAAEDA+VTLALHQAMWPQ+E+D KLR+IYEKIEVPTS Sbjct: 467 EVCGKGASQIGFNEVAIERATEYAAEDAEVTLALHQAMWPQIEHDDKLRFIYEKIEVPTS 526 Query: 181 VVLQKIERNGVLVDAAILATQSNELGKRMLEIEQQAYELAGQPFNLNSPKQLGEILFEKL 240 VVLQKIERNGVL+D+ L QS++LGKRMLEIEQQAY+LAGQPFNLNSPKQLGEILF KL Sbjct: 527 VVLQKIERNGVLIDSERLGQQSHDLGKRMLEIEQQAYDLAGQPFNLNSPKQLGEILFGKL 586 Query: 241 QLPVVKKTPSGTPSTDEEVLAKLAEDYPLPKILLDYRGLSKLKSTYTDKLPKMVDPTTGR 300 +LPVVKKT SG PSTDEEVL KLAEDYPLPK+LLDYRGL+KLKSTYTDKLPKMV+P TGR Sbjct: 587 ELPVVKKTASGAPSTDEEVLQKLAEDYPLPKVLLDYRGLAKLKSTYTDKLPKMVNPATGR 646 Query: 301 VHTNYAQAVAVTGRLASNDPNLQNIPIRTAEGRRIREAFIAPPGSTIVSADYSQIELRIM 360 VHTNYAQAVAVTGRL+SNDPNLQNIPIRTAEGRRIREAF+AP GS IVSADYSQIELRIM Sbjct: 647 VHTNYAQAVAVTGRLSSNDPNLQNIPIRTAEGRRIREAFVAPEGSVIVSADYSQIELRIM 706 Query: 361 AHISGDANMLKAFADGEDIHRATASEIFGVGLADVTSEQRRYAKVINFGLIYGMSAFGLA 420 AHIS D NMLKAFA+ EDIHRATA+EIFG+ V SEQRRYAKVINFGLIYGMSAFGLA Sbjct: 707 AHISEDENMLKAFANNEDIHRATAAEIFGIAPEQVESEQRRYAKVINFGLIYGMSAFGLA 766 Query: 421 GNLGIERSAAQMYIDKYFQRFSSVKQYMDDTRLEAKSQGYVETVFGRRLWLPEINSPNGP 480 NLGIER+AAQMYIDKYF RFS VK+YMD+TRL+AK++GYVETVFGRRLWLPEINSPNGP Sbjct: 767 SNLGIERAAAQMYIDKYFMRFSGVKRYMDETRLQAKARGYVETVFGRRLWLPEINSPNGP 826 Query: 481 RRQGAERAAINAPMQGTAADLIKLAMISVQGWIEQDGLQSKLIMQVHDELVMEVPDAELA 540 RRQGAERAAINAPMQGTAADLIK+AMI+VQ W+E + LQ+++IMQVHDELV+EVP EL Sbjct: 827 RRQGAERAAINAPMQGTAADLIKMAMIAVQDWLETNSLQTRMIMQVHDELVLEVPQQELE 886 Query: 541 LVREKLPELMKNVAELKVPLIAEVGAGKNWDQAH 574 +VREKLPELMKNVAELKVPL+AEVG GKNWD+AH Sbjct: 887 MVREKLPELMKNVAELKVPLLAEVGIGKNWDEAH 920 >Q0K851.1 Q0K851_CUPNH DNA polymerase I EC=2.7.7.7 Length = 938 Score = 890 bits (2299), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/579 (73%), Positives = 493/579 (85%), Gaps = 5/579 (0%) Query: 1 VDTETTSLVPMQAQLVGISLCCEAGRAAYIPVAHNYQDMPA-----QLPRELVLAKLKPW 55 +DTETTSL PMQAQLVGISL E G A YIPVAH D+ QL RE VL +++ W Sbjct: 360 IDTETTSLDPMQAQLVGISLSVEPGVACYIPVAHRGPDVAGLPDHGQLSREFVLGRMRAW 419 Query: 56 LEDDSKPKLGQNLKYDSHIFANQGIQLRGIVHDTLLESYVFESHRTHDMDSLALRHLNRT 115 LED S+PKLGQNLKYD H+FAN G++LRG+ HDT+L+SYV SHR H MDSLA R L+ Sbjct: 420 LEDASRPKLGQNLKYDVHVFANHGVKLRGVAHDTMLQSYVLASHRNHGMDSLAERLLSLK 479 Query: 116 TISYTDVCGKGASQICFDQVEIGRATEYAAEDADVTLALHQAMWPQVENDAKLRYIYEKI 175 TI+Y +VCGKGASQI FDQ+++ RATEYAAEDADVTL LH+ M+PQVE A LR +YE+I Sbjct: 480 TITYEEVCGKGASQIGFDQIDLARATEYAAEDADVTLRLHRKMFPQVEAAAGLRRVYEEI 539 Query: 176 EVPTSVVLQKIERNGVLVDAAILATQSNELGKRMLEIEQQAYELAGQPFNLNSPKQLGEI 235 E+P SVVLQK+ERNGVL+DA LA QS ELG+RML +EQ AYE AGQPFNL SPKQ+GEI Sbjct: 540 EMPVSVVLQKVERNGVLIDAERLAAQSAELGQRMLALEQAAYEAAGQPFNLGSPKQIGEI 599 Query: 236 LFEKLQLPVVKKTPSGTPSTDEEVLAKLAEDYPLPKILLDYRGLSKLKSTYTDKLPKMVD 295 LF +++LPVVKKT SG PSTDEEVL KLAEDYPLPK+LLDYRGL+KLKSTYTDKLPKMV+ Sbjct: 600 LFSQMKLPVVKKTASGAPSTDEEVLQKLAEDYPLPKLLLDYRGLAKLKSTYTDKLPKMVN 659 Query: 296 PTTGRVHTNYAQAVAVTGRLASNDPNLQNIPIRTAEGRRIREAFIAPPGSTIVSADYSQI 355 P TGRVHT+Y QA AVTGRLAS +PNLQNIP+RT EGRRIREAFIA PGS IVSADYSQI Sbjct: 660 PQTGRVHTSYGQATAVTGRLASTEPNLQNIPVRTEEGRRIREAFIAEPGSVIVSADYSQI 719 Query: 356 ELRIMAHISGDANMLKAFADGEDIHRATASEIFGVGLADVTSEQRRYAKVINFGLIYGMS 415 ELRIMAHISGD N+L+AFA+GEDIHRATA EIFGV V+SEQRRYAKVINFGLIYGMS Sbjct: 720 ELRIMAHISGDENLLRAFANGEDIHRATAGEIFGVEREAVSSEQRRYAKVINFGLIYGMS 779 Query: 416 AFGLAGNLGIERSAAQMYIDKYFQRFSSVKQYMDDTRLEAKSQGYVETVFGRRLWLPEIN 475 AFGLAGNLGIER AA+ YID+YF R+ V YM++TR A+ QGYVETVFGRRLWLP+IN Sbjct: 780 AFGLAGNLGIEREAAKHYIDRYFMRYPGVAHYMEETRQTAREQGYVETVFGRRLWLPDIN 839 Query: 476 SPNGPRRQGAERAAINAPMQGTAADLIKLAMISVQGWIEQDGLQSKLIMQVHDELVMEVP 535 +GPRRQ AERAAINAPMQGTAADLIKL+MI+VQGW+E+DGLQ++ IMQVHDELV+EVP Sbjct: 840 GGSGPRRQAAERAAINAPMQGTAADLIKLSMIAVQGWLERDGLQTRQIMQVHDELVLEVP 899 Query: 536 DAELALVREKLPELMKNVAELKVPLIAEVGAGKNWDQAH 574 + EL LV+ +LPELM +VA+L+VPL+AEVG+G NW++AH Sbjct: 900 EHELELVKVRLPELMCSVAQLRVPLVAEVGSGANWEEAH 938