BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0054.p (459 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWB5.1 D8IWB5_HERSS Biotin carboxylase protein EC=6.3.4.14 896 0.0 A4G8P3.1 A4G8P3_HERAR Biotin carboxylase (Acetyl-CoA carboxylase... 843 0.0 A6T2B5.1 A6T2B5_JANMA Biotin carboxylase EC=6.3.4.14 839 0.0 Q46XA6.1 Q46XA6_CUPPJ Acetyl-CoA carboxylase, biotin carboxylase 818 0.0 B3R6U2.1 B3R6U2_CUPTR Biotin carboxylase (Acetyl-CoA carboxylase... 817 0.0 >D8IWB5.1 D8IWB5_HERSS Biotin carboxylase protein EC=6.3.4.14 Length = 459 Score = 896 bits (2315), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/459 (96%), Positives = 450/459 (98%) Query: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADREAKYVKLADESVCIGPAPSALSY 60 MFEKILIANRGEIALRIQRACRE+GIKTVVVHSEADREAKYVKLADESVCIGPAPS LSY Sbjct: 1 MFEKILIANRGEIALRIQRACRELGIKTVVVHSEADREAKYVKLADESVCIGPAPSTLSY 60 Query: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPRPENIRMMGDKVSAK 120 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPR ENIRMMGDKVSAK Sbjct: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPRAENIRMMGDKVSAK 120 Query: 121 QAMIRAGVPCVPGSEGALPDNPKEIVQAARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 QAMIRAGVPCVPGS+GALPDNPKEIVQ ARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN Sbjct: 121 QAMIRAGVPCVPGSDGALPDNPKEIVQIARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 Query: 181 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI 240 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI Sbjct: 181 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI 240 Query: 241 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT 300 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT Sbjct: 241 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT 300 Query: 301 EMITGVDIVQEQIRIAFGEKLRYRQRDIELKGHAIECRINAEDPFKFTPSPGRLTAWHVP 360 EMITGVDIVQEQIRIA GEKLRYRQRDIELKGHAIECRINAEDPFKF PSPGR+TAWHVP Sbjct: 301 EMITGVDIVQEQIRIAAGEKLRYRQRDIELKGHAIECRINAEDPFKFIPSPGRITAWHVP 360 Query: 361 GGPGIRVDSHAYAGYFVPPNYDSMVGKVISYGSTREQAIRRMQIALSEMVVEGISTNIPL 420 GGPGIRVDSHAY+GYFVPPNYDSMVGKVI+YG+TREQAIRRMQIALSEMVVEGISTNIPL Sbjct: 361 GGPGIRVDSHAYSGYFVPPNYDSMVGKVIAYGATREQAIRRMQIALSEMVVEGISTNIPL 420 Query: 421 HRELMVDARFIEGGTNIHYLEHKLSERPTAPAADKPVKK 459 HRELMVDARF EGGTNIHYLEHKLSERP +P ADK +KK Sbjct: 421 HRELMVDARFFEGGTNIHYLEHKLSERPASPEADKAIKK 459 >A4G8P3.1 A4G8P3_HERAR Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC) EC=6.3.4.14 EC=6.4.1.2 Length = 456 Score = 843 bits (2179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/455 (90%), Positives = 435/455 (95%) Query: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADREAKYVKLADESVCIGPAPSALSY 60 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADR+AKYVKLADESVCIGPAPS LSY Sbjct: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADRDAKYVKLADESVCIGPAPSTLSY 60 Query: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPRPENIRMMGDKVSAK 120 LNMPAIISAAEVTDA+AIHPGYGFLSENADFAERVE+SGFVFIGPR E+IRMMGDKV+AK Sbjct: 61 LNMPAIISAAEVTDAEAIHPGYGFLSENADFAERVEQSGFVFIGPRSESIRMMGDKVTAK 120 Query: 121 QAMIRAGVPCVPGSEGALPDNPKEIVQAARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 Q MI+AGVPCVPGS+GALPD+PKEI+Q ARK+GYPVIIKAAGGGGGRGMRVVHTEAAL+N Sbjct: 121 QTMIKAGVPCVPGSDGALPDDPKEIIQTARKVGYPVIIKAAGGGGGRGMRVVHTEAALLN 180 Query: 181 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI 240 AVTMTKTEAG+AFGNPEVYMEKYLENPRHVEIQILADEHK AIWLGERDCSMQRRHQKV+ Sbjct: 181 AVTMTKTEAGSAFGNPEVYMEKYLENPRHVEIQILADEHKNAIWLGERDCSMQRRHQKVL 240 Query: 241 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT 300 EEAPAPGIPRK IE+IG+RCAEACRKM YRGAGTFEFLYEN EFYFIEMNTRVQVEHPVT Sbjct: 241 EEAPAPGIPRKTIERIGDRCAEACRKMGYRGAGTFEFLYENGEFYFIEMNTRVQVEHPVT 300 Query: 301 EMITGVDIVQEQIRIAFGEKLRYRQRDIELKGHAIECRINAEDPFKFTPSPGRLTAWHVP 360 EMITG+DIVQEQIRIA GEKLRYRQRDI L GHAIECRINAEDPFKFTPSPG++ +WH P Sbjct: 301 EMITGIDIVQEQIRIAAGEKLRYRQRDIVLNGHAIECRINAEDPFKFTPSPGKIVSWHAP 360 Query: 361 GGPGIRVDSHAYAGYFVPPNYDSMVGKVISYGSTREQAIRRMQIALSEMVVEGISTNIPL 420 GGPGIRVDSHAYAGY+VPP+YDSMVGKVISYG+TREQAI+RMQIALSEMVVEGISTNIPL Sbjct: 361 GGPGIRVDSHAYAGYYVPPHYDSMVGKVISYGATREQAIKRMQIALSEMVVEGISTNIPL 420 Query: 421 HRELMVDARFIEGGTNIHYLEHKLSERPTAPAADK 455 HRELMVDARFIEGGTNIHYLE KL+ +P P K Sbjct: 421 HRELMVDARFIEGGTNIHYLEQKLANKPDLPKEPK 455 >A6T2B5.1 A6T2B5_JANMA Biotin carboxylase EC=6.3.4.14 Length = 453 Score = 839 bits (2167), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/451 (90%), Positives = 434/451 (96%) Query: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADREAKYVKLADESVCIGPAPSALSY 60 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADR+AKYVKLADESVCIGPAPS+LSY Sbjct: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADRDAKYVKLADESVCIGPAPSSLSY 60 Query: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPRPENIRMMGDKVSAK 120 LNMPAIISAAEVTDA+AIHPGYGFLSENADFAERVE+SGFVFIGPR ++IRMMGDKVSAK Sbjct: 61 LNMPAIISAAEVTDAEAIHPGYGFLSENADFAERVEQSGFVFIGPRSDSIRMMGDKVSAK 120 Query: 121 QAMIRAGVPCVPGSEGALPDNPKEIVQAARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 QAMI+AGVPCVPGSEGALPD+ KEIVQ ARKIGYPVIIKAAGGGGGRGMRVVHTEAAL+N Sbjct: 121 QAMIKAGVPCVPGSEGALPDDAKEIVQIARKIGYPVIIKAAGGGGGRGMRVVHTEAALLN 180 Query: 181 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI 240 AVTMTKTEAG+AFGNPEVYMEKYLENPRHVEIQILADEHK AIWLGERDCSMQRRHQKV+ Sbjct: 181 AVTMTKTEAGSAFGNPEVYMEKYLENPRHVEIQILADEHKNAIWLGERDCSMQRRHQKVL 240 Query: 241 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT 300 EEAPAPGIPRK IE+IG+RCAEACRKM YRGAGTFEFLYEN EFYFIEMNTRVQVEHPVT Sbjct: 241 EEAPAPGIPRKTIERIGDRCAEACRKMGYRGAGTFEFLYENGEFYFIEMNTRVQVEHPVT 300 Query: 301 EMITGVDIVQEQIRIAFGEKLRYRQRDIELKGHAIECRINAEDPFKFTPSPGRLTAWHVP 360 EMITG+DIVQEQIRIA GEKLR+RQRD+ L GHAIECRINAEDPFKFTPSPG++ +WH P Sbjct: 301 EMITGIDIVQEQIRIAAGEKLRFRQRDVILSGHAIECRINAEDPFKFTPSPGKIVSWHAP 360 Query: 361 GGPGIRVDSHAYAGYFVPPNYDSMVGKVISYGSTREQAIRRMQIALSEMVVEGISTNIPL 420 GGPGIRVDSHAYAGY+VPP+YDSMVGKVI+YG+TREQAI+RMQIALSEMVVEGI TNIPL Sbjct: 361 GGPGIRVDSHAYAGYYVPPHYDSMVGKVIAYGATREQAIKRMQIALSEMVVEGIQTNIPL 420 Query: 421 HRELMVDARFIEGGTNIHYLEHKLSERPTAP 451 HRELMVDARFIEGGTNIHYLE KL+ +P P Sbjct: 421 HRELMVDARFIEGGTNIHYLEQKLANKPDLP 451 >Q46XA6.1 Q46XA6_CUPPJ Acetyl-CoA carboxylase, biotin carboxylase Length = 450 Score = 818 bits (2113), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/450 (86%), Positives = 431/450 (95%) Query: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADREAKYVKLADESVCIGPAPSALSY 60 MFEKILIANRGEIALRIQRACRE+GIKTVVV+SEAD+EAKYVKLADE+VCIGPAPS LSY Sbjct: 1 MFEKILIANRGEIALRIQRACRELGIKTVVVYSEADKEAKYVKLADEAVCIGPAPSPLSY 60 Query: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPRPENIRMMGDKVSAK 120 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGP E+IR+MGDKVSAK Sbjct: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPTAESIRLMGDKVSAK 120 Query: 121 QAMIRAGVPCVPGSEGALPDNPKEIVQAARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 QAMI+AGVPCVPGSEGALPD+P EIV AAR++GYPVIIKAAGGGGGRGMRVVHTEAAL+N Sbjct: 121 QAMIKAGVPCVPGSEGALPDDPAEIVAAARRVGYPVIIKAAGGGGGRGMRVVHTEAALVN 180 Query: 181 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI 240 AV MT+ EAG AFGNPEVYMEK+LENPRHVEIQILAD+HKQAIWLGERDCSMQRRHQKVI Sbjct: 181 AVNMTREEAGRAFGNPEVYMEKFLENPRHVEIQILADQHKQAIWLGERDCSMQRRHQKVI 240 Query: 241 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT 300 EEAPAP IPR++IE+IG+RCAEACRKM YRGAGTFEFLYEN EFYFIEMNTRVQVEHPVT Sbjct: 241 EEAPAPHIPRRLIERIGDRCAEACRKMGYRGAGTFEFLYENNEFYFIEMNTRVQVEHPVT 300 Query: 301 EMITGVDIVQEQIRIAFGEKLRYRQRDIELKGHAIECRINAEDPFKFTPSPGRLTAWHVP 360 EMITG+DIVQEQIRIAFGEKLRYRQ+D++ +GHAIECR+NAEDPFKF PSPGR+TAWH+P Sbjct: 301 EMITGIDIVQEQIRIAFGEKLRYRQKDVQFRGHAIECRVNAEDPFKFIPSPGRITAWHMP 360 Query: 361 GGPGIRVDSHAYAGYFVPPNYDSMVGKVISYGSTREQAIRRMQIALSEMVVEGISTNIPL 420 GGPG+RVDSHAY GYFVPPNYDSM+GK+I+YG+TREQAI RM+IALSEMVV+GI TN+PL Sbjct: 361 GGPGVRVDSHAYDGYFVPPNYDSMIGKIITYGATREQAIARMRIALSEMVVDGIQTNVPL 420 Query: 421 HRELMVDARFIEGGTNIHYLEHKLSERPTA 450 HRELM+DA F+EGGT+IHYLEH+L++R A Sbjct: 421 HRELMMDANFVEGGTSIHYLEHRLAQREKA 450 >B3R6U2.1 B3R6U2_CUPTR Biotin carboxylase (Acetyl-CoA carboxylase subunit A) EC=6.3.4.14 EC=6.4.1.- Length = 450 Score = 817 bits (2110), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/450 (86%), Positives = 432/450 (96%) Query: 1 MFEKILIANRGEIALRIQRACREMGIKTVVVHSEADREAKYVKLADESVCIGPAPSALSY 60 MFEKILIANRGEIALRIQRACRE+GIKTVVV+SEAD+EAKYV+LADE+VCIGPAPS LSY Sbjct: 1 MFEKILIANRGEIALRIQRACRELGIKTVVVYSEADKEAKYVRLADEAVCIGPAPSPLSY 60 Query: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPRPENIRMMGDKVSAK 120 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGP ++IR+MGDKVSAK Sbjct: 61 LNMPAIISAAEVTDAQAIHPGYGFLSENADFAERVEKSGFVFIGPTADSIRLMGDKVSAK 120 Query: 121 QAMIRAGVPCVPGSEGALPDNPKEIVQAARKIGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 QAMI+AGVPCVPGS+GALPD+PKEI+ AR++GYPVIIKAAGGGGGRGMRVVHTEAALIN Sbjct: 121 QAMIKAGVPCVPGSDGALPDDPKEILATARRVGYPVIIKAAGGGGGRGMRVVHTEAALIN 180 Query: 181 AVTMTKTEAGAAFGNPEVYMEKYLENPRHVEIQILADEHKQAIWLGERDCSMQRRHQKVI 240 AV MT+ EAG AFGNPEVYMEK+LENPRHVEIQILAD+HKQAIWLGERDCSMQRRHQKVI Sbjct: 181 AVNMTREEAGRAFGNPEVYMEKFLENPRHVEIQILADQHKQAIWLGERDCSMQRRHQKVI 240 Query: 241 EEAPAPGIPRKIIEKIGERCAEACRKMNYRGAGTFEFLYENEEFYFIEMNTRVQVEHPVT 300 EEAPAP IPR++IE+IG+RCAEAC+KM YRGAGTFEFLYEN EFYFIEMNTRVQVEHPVT Sbjct: 241 EEAPAPHIPRRLIERIGDRCAEACKKMGYRGAGTFEFLYENNEFYFIEMNTRVQVEHPVT 300 Query: 301 EMITGVDIVQEQIRIAFGEKLRYRQRDIELKGHAIECRINAEDPFKFTPSPGRLTAWHVP 360 EMITG+DIVQEQIRIAFGEKLR+RQ+D++ +GHAIECR+NAEDPFKFTPSPGR+TAWH+P Sbjct: 301 EMITGIDIVQEQIRIAFGEKLRFRQKDVQFRGHAIECRVNAEDPFKFTPSPGRITAWHMP 360 Query: 361 GGPGIRVDSHAYAGYFVPPNYDSMVGKVISYGSTREQAIRRMQIALSEMVVEGISTNIPL 420 GGPG+RVDSHAY GYFVPPNYDSM+GK+ISYG+TREQAI RM+IALSEMVV+GI TN+PL Sbjct: 361 GGPGVRVDSHAYDGYFVPPNYDSMIGKIISYGATREQAIARMRIALSEMVVDGIQTNVPL 420 Query: 421 HRELMVDARFIEGGTNIHYLEHKLSERPTA 450 HRELM+DA F+EGGT+IHYLEH+L+ER A Sbjct: 421 HRELMMDANFVEGGTSIHYLEHRLAERAKA 450