BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0083.p (295 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IU54.1 D8IU54_HERSS Nicotinate-nucleotide pyrophosphorylase pr... 460 e-127 F1VVS5.1 F1VVS5_9BURK Quinolinate phosphoribosyltransferase (Dec... 423 e-116 A6SZJ2.1 A6SZJ2_JANMA Nicotinate-nucleotide pyrophosphorylase (C... 399 e-109 A4G432.1 A4G432_HERAR Nicotinate-nucleotide pyrophosphorylase [c... 398 e-109 C6BCB6.1 C6BCB6_RALP1 Nicotinate-nucleotide pyrophosphorylase EC... 392 e-107 >D8IU54.1 D8IU54_HERSS Nicotinate-nucleotide pyrophosphorylase protein EC=2.4.2.19 Length = 301 Score = 460 bits (1184), Expect = e-127, Method: Compositional matrix adjust. Identities = 240/294 (81%), Positives = 265/294 (90%) Query: 2 SLTVSSTSNLRNPFAPFDPALSAAFDANVNLAIAEDVGNGDHTGKLVPENEHVKARVIVR 61 S + + SNLRNPF PFD AL AAFDANVN AIAEDVG+ D+TG LVPE+E VKARVIVR Sbjct: 8 SASTIAASNLRNPFGPFDAALHAAFDANVNQAIAEDVGDCDYTGLLVPESEFVKARVIVR 67 Query: 62 EQAVLCGAPWFEAVMARLDPRLRVDWKFGEGDLMPADAEVCRIEGPARALLTAERGALNF 121 E AVLCGAPWFEAVM RLDPRL+V W++ EG+ M AD+EVC IEGPARALLTAERGALNF Sbjct: 68 EAAVLCGAPWFEAVMTRLDPRLQVSWRYAEGERMAADSEVCTIEGPARALLTAERGALNF 127 Query: 122 LQLLSGVATATHRYVDLIRDTRARILDTRKTLPGLRLAQKYAVRVGGGMNQRLALYDGIL 181 LQLLSGVA+AT RYVD+++ TRA ILDTRKTLPGLRLAQKYAVRVGGG+NQRLALYDGIL Sbjct: 128 LQLLSGVASATRRYVDVVQGTRASILDTRKTLPGLRLAQKYAVRVGGGVNQRLALYDGIL 187 Query: 182 IKENHIAAAGGITAAVTAAIKLNAGVSIQVEVESIDELGEALAAGATSILLDNFSLDMMR 241 IKENHIAAAGGITAAV AA+KLNAGVSIQVEVESIDEL EAL AGA SILLDNFSL+MMR Sbjct: 188 IKENHIAAAGGITAAVAAALKLNAGVSIQVEVESIDELKEALQAGARSILLDNFSLEMMR 247 Query: 242 EGVMINARRAVLEASGGINMETVRAIAETGVDRISVGSLTKDLQAIDYSLRIIG 295 E V +NA RA+LEASGGINM+TVRAIAETGVDRIS+GSLTKD+QA D+SLR++G Sbjct: 248 EAVTVNAGRALLEASGGINMQTVRAIAETGVDRISIGSLTKDVQATDFSLRVVG 301 >F1VVS5.1 F1VVS5_9BURK Quinolinate phosphoribosyltransferase (Decarboxylating) Length = 285 Score = 423 bits (1088), Expect = e-116, Method: Compositional matrix adjust. Identities = 208/282 (73%), Positives = 242/282 (85%) Query: 13 NPFAPFDPALSAAFDANVNLAIAEDVGNGDHTGKLVPENEHVKARVIVREQAVLCGAPWF 72 NPFAPF+PAL+AA ANV LA+AEDVG+GD TG LVP+N V+ARVIVRE AVLCGAPWF Sbjct: 2 NPFAPFEPALAAALQANVALALAEDVGSGDVTGLLVPDNAIVQARVIVREAAVLCGAPWF 61 Query: 73 EAVMARLDPRLRVDWKFGEGDLMPADAEVCRIEGPARALLTAERGALNFLQLLSGVATAT 132 EAVM +LD R+R+DW++ EG+LM AD+ VC+IE PARALLT ER ALNFLQ++SGVA+ T Sbjct: 62 EAVMTQLDARIRIDWQYDEGELMRADSVVCQIEAPARALLTGERSALNFLQMMSGVASQT 121 Query: 133 HRYVDLIRDTRARILDTRKTLPGLRLAQKYAVRVGGGMNQRLALYDGILIKENHIAAAGG 192 RYV+L+ T A ILDTRKTLPGLRLAQKYAVRVGGG NQRLALYDGILIKENHIAAAGG Sbjct: 122 RRYVELVAGTAAGILDTRKTLPGLRLAQKYAVRVGGGANQRLALYDGILIKENHIAAAGG 181 Query: 193 ITAAVTAAIKLNAGVSIQVEVESIDELGEALAAGATSILLDNFSLDMMREGVMINARRAV 252 + A+ A LNAGV+IQ+EVESID+L EALAAGA S+LLDNFSL MRE V + + A+ Sbjct: 182 VRLAMEKAFALNAGVTIQIEVESIDQLKEALAAGARSVLLDNFSLAQMREAVTLTSGAAL 241 Query: 253 LEASGGINMETVRAIAETGVDRISVGSLTKDLQAIDYSLRII 294 LEASGGIN +TVRAI+ETGVDRIS+GSLTKD++A DYSLRI+ Sbjct: 242 LEASGGINFDTVRAISETGVDRISIGSLTKDVRATDYSLRIV 283 >A6SZJ2.1 A6SZJ2_JANMA Nicotinate-nucleotide pyrophosphorylase (Carboxylating) EC=2.4.2.19 Length = 290 Score = 399 bits (1026), Expect = e-109, Method: Compositional matrix adjust. Identities = 210/286 (73%), Positives = 242/286 (84%) Query: 9 SNLRNPFAPFDPALSAAFDANVNLAIAEDVGNGDHTGKLVPENEHVKARVIVREQAVLCG 68 S LRNPFAPFD AL+AAF+ N+ A+AEDVG GD TGKLVPE E V+ARVIVRE AVLCG Sbjct: 2 SLLRNPFAPFDAALAAAFERNIETALAEDVGTGDVTGKLVPEQEVVQARVIVREAAVLCG 61 Query: 69 APWFEAVMARLDPRLRVDWKFGEGDLMPADAEVCRIEGPARALLTAERGALNFLQLLSGV 128 APWFE VM RLD R+++ W + EGD+M AD+EVC IE PARALLTAER ALNFLQLLSGV Sbjct: 62 APWFECVMKRLDARIKITWHYAEGDVMTADSEVCAIEAPARALLTAERSALNFLQLLSGV 121 Query: 129 ATATHRYVDLIRDTRARILDTRKTLPGLRLAQKYAVRVGGGMNQRLALYDGILIKENHIA 188 A+AT Y ++ T+A ILDTRKTLPGLRLAQKYAVRVGGG NQRLALYDGILIKENHIA Sbjct: 122 ASATREYTGIVSGTKAAILDTRKTLPGLRLAQKYAVRVGGGKNQRLALYDGILIKENHIA 181 Query: 189 AAGGITAAVTAAIKLNAGVSIQVEVESIDELGEALAAGATSILLDNFSLDMMREGVMINA 248 AAGG+ AA+ AA+ L AGV+IQ+EVE++ EL +AL AGA S+LLDNFSL MRE V + A Sbjct: 182 AAGGVRAAMEAALALKAGVTIQIEVENLAELKDALDAGAESVLLDNFSLADMREAVALTA 241 Query: 249 RRAVLEASGGINMETVRAIAETGVDRISVGSLTKDLQAIDYSLRII 294 RA+LEASGGIN ET+RAIAETGVDRIS+G+LTKD++A DYSLRI+ Sbjct: 242 GRALLEASGGINRETLRAIAETGVDRISIGALTKDIRATDYSLRIV 287 >A4G432.1 A4G432_HERAR Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) EC=2.4.2.19 Length = 290 Score = 398 bits (1022), Expect = e-109, Method: Compositional matrix adjust. Identities = 212/286 (74%), Positives = 247/286 (86%) Query: 9 SNLRNPFAPFDPALSAAFDANVNLAIAEDVGNGDHTGKLVPENEHVKARVIVREQAVLCG 68 S LRNPFAPFD AL+AAF+ N+ A+AEDVG+GD TGKLVPE+E V+ARVIVRE AVLCG Sbjct: 2 SLLRNPFAPFDAALTAAFEDNIVTALAEDVGSGDVTGKLVPEHEIVQARVIVREAAVLCG 61 Query: 69 APWFEAVMARLDPRLRVDWKFGEGDLMPADAEVCRIEGPARALLTAERGALNFLQLLSGV 128 APWFEAVM ++D R+R++W++ EG LM AD+EVC IE PARALLTAER ALNFLQLLSGV Sbjct: 62 APWFEAVMKQVDARIRIEWRYAEGALMQADSEVCAIEAPARALLTAERTALNFLQLLSGV 121 Query: 129 ATATHRYVDLIRDTRARILDTRKTLPGLRLAQKYAVRVGGGMNQRLALYDGILIKENHIA 188 ATAT YV+LI T+A ILDTRKTLPGLRLAQKYAVRVGGG NQRLALYDGILIKENHIA Sbjct: 122 ATATRAYVELIAGTKAAILDTRKTLPGLRLAQKYAVRVGGGKNQRLALYDGILIKENHIA 181 Query: 189 AAGGITAAVTAAIKLNAGVSIQVEVESIDELGEALAAGATSILLDNFSLDMMREGVMINA 248 AAGG+TAA+ AA+ L AGV+IQ+EVE++ +L ALAAGA S+LLDNFSL MR V++ Sbjct: 182 AAGGVTAAMQAALALQAGVTIQIEVENLAQLEAALAAGAQSVLLDNFSLSDMRTAVVLTN 241 Query: 249 RRAVLEASGGINMETVRAIAETGVDRISVGSLTKDLQAIDYSLRII 294 RA+LEASGG+N ++VRAIAETGVDRIS+G LTKD++A DYSLRII Sbjct: 242 GRALLEASGGVNRDSVRAIAETGVDRISIGGLTKDVRATDYSLRII 287 >C6BCB6.1 C6BCB6_RALP1 Nicotinate-nucleotide pyrophosphorylase EC=2.4.2.19 Length = 299 Score = 392 bits (1007), Expect = e-107, Method: Compositional matrix adjust. Identities = 195/280 (69%), Positives = 225/280 (80%) Query: 15 FAPFDPALSAAFDANVNLAIAEDVGNGDHTGKLVPENEHVKARVIVREQAVLCGAPWFEA 74 F F PAL A ANV AIAEDVG GD TG L+P + H +ARVIVRE AVLCG PWF+A Sbjct: 19 FDSFGPALREALSANVATAIAEDVGTGDRTGLLIPADRHARARVIVREHAVLCGTPWFDA 78 Query: 75 VMARLDPRLRVDWKFGEGDLMPADAEVCRIEGPARALLTAERGALNFLQLLSGVATATHR 134 M +D LRV W+ EGD M D+ VC IEGPAR+LLTAER +LNFLQLLSGVATAT R Sbjct: 79 CMRAVDSALRVTWRQHEGDCMSPDSVVCEIEGPARSLLTAERPSLNFLQLLSGVATATSR 138 Query: 135 YVDLIRDTRARILDTRKTLPGLRLAQKYAVRVGGGMNQRLALYDGILIKENHIAAAGGIT 194 Y + TRAR+LDTRKTLPGLRLAQKYAVR+GGG NQRLALYDGILIKENHIAAAGG+T Sbjct: 139 YAAAVEGTRARVLDTRKTLPGLRLAQKYAVRIGGGENQRLALYDGILIKENHIAAAGGVT 198 Query: 195 AAVTAAIKLNAGVSIQVEVESIDELGEALAAGATSILLDNFSLDMMREGVMINARRAVLE 254 AA+ AA LNAGV+IQ+EVE++ +L EALAAGATS+LLDNF MRE V + A RA+LE Sbjct: 199 AALRAAQALNAGVTIQIEVETLAQLDEALAAGATSVLLDNFEPPAMREAVRVTAGRALLE 258 Query: 255 ASGGINMETVRAIAETGVDRISVGSLTKDLQAIDYSLRII 294 SGG+N+ET+R AETGVDRISVG+LTKD++A D+SLRI+ Sbjct: 259 VSGGVNIETIRTFAETGVDRISVGALTKDVRATDFSLRIV 298