BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0068.p (274 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IU43.1 D8IU43_HERSS GMP synthase [glutamine-hydrolyzing] EC=6.... 536 e-150 A2RPT0.1 A2RPT0_HERSE GMP synthase [glutamine-hydrolyzing] EC=6.... 536 e-150 F1VZE8.1 F1VZE8_9BURK GMP synthase (Glutamine-hydrolyzing) 503 e-140 A6SZM5.1 GUAA_JANMA GMP synthase [glutamine-hydrolyzing] EC=6.3.5.2 501 e-140 B1XTW6.1 GUAA_POLNS GMP synthase [glutamine-hydrolyzing] EC=6.3.5.2 501 e-140 >D8IU43.1 D8IU43_HERSS GMP synthase [glutamine-hydrolyzing] EC=6.3.5.2 Length = 530 Score = 536 bits (1382), Expect = e-150, Method: Compositional matrix adjust. Identities = 262/274 (95%), Positives = 266/274 (97%) Query: 1 VFVDHGLLRLDEGKMVMEMFGKNLGVKVIHVDATDQFMGHLAGVTDPEAKRKIIGREFVE 60 VFVDHGLLRLDEGKMVMEMF KNLGVKVIHVDAT QFMGHLAGVTDPEAKRKIIGREFVE Sbjct: 257 VFVDHGLLRLDEGKMVMEMFAKNLGVKVIHVDATAQFMGHLAGVTDPEAKRKIIGREFVE 316 Query: 61 VFQAESGKLKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPETLNLKLLEPLR 120 VFQAES KL +AKWLAQGTIYPDVIESAGKGKK AHTIKSHHNVGGLPETLNLKLLEPLR Sbjct: 317 VFQAESAKLTSAKWLAQGTIYPDVIESAGKGKKTAHTIKSHHNVGGLPETLNLKLLEPLR 376 Query: 121 ELFKDEVRELGVALGLPHEMVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELRN 180 ELFKDEVRELGVALGLP EMVYRHPFPGPGLGVRILGEVKKE+ADLLRRADAIFIEELRN Sbjct: 377 ELFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRN 436 Query: 181 TKDADGQSWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPHE 240 TKD DGQ+WYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPHE Sbjct: 437 TKDEDGQTWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPHE 496 Query: 241 LLGHVSNRIINEVRGINRVVYDISGKPPATIEWE 274 LLG VSNRIINEVRG+NRVVYDISGKPPATIEWE Sbjct: 497 LLGRVSNRIINEVRGLNRVVYDISGKPPATIEWE 530 >A2RPT0.1 A2RPT0_HERSE GMP synthase [glutamine-hydrolyzing] EC=6.3.5.2 Length = 530 Score = 536 bits (1382), Expect = e-150, Method: Compositional matrix adjust. Identities = 262/274 (95%), Positives = 266/274 (97%) Query: 1 VFVDHGLLRLDEGKMVMEMFGKNLGVKVIHVDATDQFMGHLAGVTDPEAKRKIIGREFVE 60 VFVDHGLLRLDEGKMVMEMF KNLGVKVIHVDAT QFMGHLAGVTDPEAKRKIIGREFVE Sbjct: 257 VFVDHGLLRLDEGKMVMEMFAKNLGVKVIHVDATAQFMGHLAGVTDPEAKRKIIGREFVE 316 Query: 61 VFQAESGKLKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPETLNLKLLEPLR 120 VFQAES KL +AKWLAQGTIYPDVIESAGKGKK AHTIKSHHNVGGLPETLNLKLLEPLR Sbjct: 317 VFQAESAKLTSAKWLAQGTIYPDVIESAGKGKKTAHTIKSHHNVGGLPETLNLKLLEPLR 376 Query: 121 ELFKDEVRELGVALGLPHEMVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELRN 180 ELFKDEVRELGVALGLP EMVYRHPFPGPGLGVRILGEVKKE+ADLLRRADAIFIEELRN Sbjct: 377 ELFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRN 436 Query: 181 TKDADGQSWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPHE 240 TKD DGQ+WYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPHE Sbjct: 437 TKDEDGQTWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPHE 496 Query: 241 LLGHVSNRIINEVRGINRVVYDISGKPPATIEWE 274 LLG VSNRIINEVRG+NRVVYDISGKPPATIEWE Sbjct: 497 LLGRVSNRIINEVRGLNRVVYDISGKPPATIEWE 530 >F1VZE8.1 F1VZE8_9BURK GMP synthase (Glutamine-hydrolyzing) Length = 534 Score = 503 bits (1294), Expect = e-140, Method: Compositional matrix adjust. Identities = 252/283 (89%), Positives = 258/283 (91%), Gaps = 10/283 (3%) Query: 1 VFVDHGLLRLDEGKMVMEMFGKNLGVKVIHVDATDQFMGHLAGVTDPEAKRKIIGREFVE 60 VFVDHGLLRL+EG MVM+MF NLGVKVI VDATDQFMGHLAGVTDPEAKRKIIGREFVE Sbjct: 253 VFVDHGLLRLNEGDMVMDMFATNLGVKVIRVDATDQFMGHLAGVTDPEAKRKIIGREFVE 312 Query: 61 VFQAESGKLKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPETLNLKLLEPLR 120 VFQ ES KLKNAKWLAQGTIYPDVIESAGKGKKG HTIKSHHNVGGLPETLNLKLLEPLR Sbjct: 313 VFQVESAKLKNAKWLAQGTIYPDVIESAGKGKKG-HTIKSHHNVGGLPETLNLKLLEPLR 371 Query: 121 ELFKDEVRELGVALGLPHEMVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELRN 180 ELFKDEVR LGVALGLP MVYRHPFPGPGLGVRILGEVKKE+ADLLRRADAIFI+ELRN Sbjct: 372 ELFKDEVRALGVALGLPATMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIDELRN 431 Query: 181 TK-------DADG--QSWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMT 231 D G ++WYE TSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMT Sbjct: 432 CTLDLPAGIDQQGIVKNWYEGTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMT 491 Query: 232 AHWAHLPHELLGHVSNRIINEVRGINRVVYDISGKPPATIEWE 274 AHWAHLPHELLG VSNRIINEVRGINRVVYDISGKPPATIEWE Sbjct: 492 AHWAHLPHELLGRVSNRIINEVRGINRVVYDISGKPPATIEWE 534 >A6SZM5.1 GUAA_JANMA GMP synthase [glutamine-hydrolyzing] EC=6.3.5.2 Length = 539 Score = 501 bits (1290), Expect = e-140, Method: Compositional matrix adjust. Identities = 250/287 (87%), Positives = 263/287 (91%), Gaps = 14/287 (4%) Query: 1 VFVDHGLLRLDEGKMVMEMFGKNLGVKVIHVDATDQFMGHLAGVTDPEAKRKIIGREFVE 60 VFVDHGLLRLDEGKMVMEMF ++LGV VIH+DA DQFMGHLAGV+DPEAKRKIIGREFVE Sbjct: 254 VFVDHGLLRLDEGKMVMEMFAESLGVNVIHIDAVDQFMGHLAGVSDPEAKRKIIGREFVE 313 Query: 61 VFQAESGKLKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPETLNLKLLEPLR 120 VFQ E+GK KNAKWLAQGTIYPDVIESAGKGKKG HTIKSHHNVGGLPETLNL+LLEPLR Sbjct: 314 VFQVEAGKRKNAKWLAQGTIYPDVIESAGKGKKG-HTIKSHHNVGGLPETLNLQLLEPLR 372 Query: 121 ELFKDEVRELGVALGLPHEMVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELRN 180 ELFKDEVR+LGVALGLPH+MVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELR Sbjct: 373 ELFKDEVRKLGVALGLPHDMVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELRK 432 Query: 181 T---------KDADG----QSWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQ 227 T + D ++WY+ TSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQ Sbjct: 433 TPFVATPGASEATDNGIPHRNWYDATSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQ 492 Query: 228 DFMTAHWAHLPHELLGHVSNRIINEVRGINRVVYDISGKPPATIEWE 274 DFMTAHWAHLPHELLG+VSNRIINEVRGINRVVYDISGKPPATIEWE Sbjct: 493 DFMTAHWAHLPHELLGNVSNRIINEVRGINRVVYDISGKPPATIEWE 539 >B1XTW6.1 GUAA_POLNS GMP synthase [glutamine-hydrolyzing] EC=6.3.5.2 Length = 535 Score = 501 bits (1290), Expect = e-140, Method: Compositional matrix adjust. Identities = 246/275 (89%), Positives = 257/275 (93%), Gaps = 1/275 (0%) Query: 1 VFVDHGLLRLDEGKMVMEMFGKNLGVKVIHVDATDQFMGHLAGVTDPEAKRKIIGREFVE 60 VFVDHGLLRL+EG MVMEMF +NLGVKVI VDA + FMG LAGV+DPEAKRKIIG+EFVE Sbjct: 261 VFVDHGLLRLNEGDMVMEMFARNLGVKVIRVDAKETFMGELAGVSDPEAKRKIIGKEFVE 320 Query: 61 VFQAESGKLKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPETLNLKLLEPLR 120 +FQAESGK+KNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPE ++LKLLEPLR Sbjct: 321 IFQAESGKIKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPEDMHLKLLEPLR 380 Query: 121 ELFKDEVRELGVALGLPHEMVYRHPFPGPGLGVRILGEVKKEFADLLRRADAIFIEELRN 180 ELFKDEVRELGVALGLP EMVYRHPFPGPGLGVRILGEVK EFA LL+RADAIFIEELRN Sbjct: 381 ELFKDEVRELGVALGLPREMVYRHPFPGPGLGVRILGEVKAEFASLLQRADAIFIEELRN 440 Query: 181 TKDADGQ-SWYEKTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPH 239 T D Q SWY+ TSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPH Sbjct: 441 TIDEVSQKSWYDLTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTQDFMTAHWAHLPH 500 Query: 240 ELLGHVSNRIINEVRGINRVVYDISGKPPATIEWE 274 ELLG V NRIINEVRGINRVVYDISGKPPATIEWE Sbjct: 501 ELLGKVFNRIINEVRGINRVVYDISGKPPATIEWE 535