BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0036.p (398 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6SZN8.1 A6SZN8_JANMA Lipid-A-disaccharide synthase EC=2.4.1.182 585 e-165 A4G4T4.1 A4G4T4_HERAR Lipid-A-disaccharide synthase EC=2.4.1.182 584 e-164 D8IU28.1 D8IU28_HERSS Lipid-A-disaccharide synthase EC=2.4.1.182 573 e-161 C3X7S5.1 C3X7S5_OXAFO Lipid-A-disaccharide synthase EC=2.4.1.182 488 e-136 C3X1G4.1 C3X1G4_OXAFO Lipid-A-disaccharide synthase EC=2.4.1.182 487 e-135 >A6SZN8.1 A6SZN8_JANMA Lipid-A-disaccharide synthase EC=2.4.1.182 Length = 394 Score = 585 bits (1508), Expect = e-165, Method: Compositional matrix adjust. Identities = 280/387 (72%), Positives = 331/387 (85%) Query: 6 VASSDNISIAMVAGESSGDLLASRLLSGLRPRLPDARLHGIGGPHMAEHGFVSDWPMDKL 65 V ++ +IAMVAGE+SGDLLASRLLSGLRP++PDA +HGIGGPHMA++GFVSD+PM+KL Sbjct: 5 VNTTAKTAIAMVAGETSGDLLASRLLSGLRPQMPDAYMHGIGGPHMAQYGFVSDFPMEKL 64 Query: 66 TVRGLFEVVPRYRELKGIQNTLRDQLLAERPSVFIGIDYPGFNLGLEQQLRDAGIPTMHF 125 +VRGLFEV+ YRE+KGIQ LRDQLL ERP+VFIG+D P FNLGLE QL+ AGIPTMHF Sbjct: 65 SVRGLFEVLAHYREIKGIQVALRDQLLDERPAVFIGVDAPDFNLGLEAQLKSAGIPTMHF 124 Query: 126 IGPQIWAWRGGRIKKIARAVSHMLVIFPFEEEIYRKAGVPVTYVGHPLAEIIPMEPDQAG 185 IGP IWAWRGGRIKKIARA SHMLVIFPFEEEIYRKAG+P TYVGHPLA++IPMEPDQA Sbjct: 125 IGPSIWAWRGGRIKKIARAASHMLVIFPFEEEIYRKAGIPATYVGHPLAQVIPMEPDQAA 184 Query: 186 ARAALGLQQDRRIVAILPGSRMSELKYNTVSFLGAARLLRQREPQLQFVAPMAGDKQRAY 245 AR L L Q +VAILPGSRMSELKYN V+F+ AA++L QR+P L+ VAPMAG QR Y Sbjct: 185 ARTLLNLPQSGPVVAILPGSRMSELKYNAVAFVAAAKILLQRDPGLRIVAPMAGAPQRRY 244 Query: 246 FEQLIAETGAVDLGIHVVSGQSHAAMEAADAVLVASGTASLEVALYKKPMVIAYKMMRAS 305 FE+LIA+ G D+ + ++ GQSH A+ AADAV+VASGTASLEVAL+K+PMVIAYKMM AS Sbjct: 245 FEELIAQAGLQDVPVQILDGQSHQALAAADAVMVASGTASLEVALFKRPMVIAYKMMSAS 304 Query: 306 YAIMRHMNYQPWVGLPNILAREFVVPELLQDAATPQALADALWKQLDDPVHCRNLRQRFT 365 + I+RHM YQPW+GLPNILA+EF+VPELLQDAATPQALADALW+QL D H L++RFT Sbjct: 305 WHILRHMAYQPWIGLPNILAQEFLVPELLQDAATPQALADALWQQLQDGAHRERLQRRFT 364 Query: 366 DMHHTLLRDTANASAQAVCALLDRQRA 392 +MHH+LLRDTA SA+AV L+ + R+ Sbjct: 365 EMHHSLLRDTAGESARAVMELIAQSRS 391 >A4G4T4.1 A4G4T4_HERAR Lipid-A-disaccharide synthase EC=2.4.1.182 Length = 393 Score = 584 bits (1505), Expect = e-164, Method: Compositional matrix adjust. Identities = 281/375 (74%), Positives = 326/375 (86%) Query: 13 SIAMVAGESSGDLLASRLLSGLRPRLPDARLHGIGGPHMAEHGFVSDWPMDKLTVRGLFE 72 +IAMVAGE+SGDLLA RLLSGLRP+LPDA +HGIGGP+MA+HGFVSD+PM+KL+VRGLFE Sbjct: 12 AIAMVAGETSGDLLAGRLLSGLRPQLPDALMHGIGGPNMAQHGFVSDFPMEKLSVRGLFE 71 Query: 73 VVPRYRELKGIQNTLRDQLLAERPSVFIGIDYPGFNLGLEQQLRDAGIPTMHFIGPQIWA 132 V+ YRE+KGIQ LRDQLLAERP+VFIG+D P FNLGLE QL+ AGIPTMHFIGP IWA Sbjct: 72 VLAHYREIKGIQIALRDQLLAERPAVFIGVDAPDFNLGLEAQLKSAGIPTMHFIGPSIWA 131 Query: 133 WRGGRIKKIARAVSHMLVIFPFEEEIYRKAGVPVTYVGHPLAEIIPMEPDQAGARAALGL 192 WRGGRIKKIARAVSHMLVIFPFEEE+YR+AG+P TYVGHPLA++IPMEPDQA AR AL L Sbjct: 132 WRGGRIKKIARAVSHMLVIFPFEEELYRQAGIPATYVGHPLAQVIPMEPDQAAARVALDL 191 Query: 193 QQDRRIVAILPGSRMSELKYNTVSFLGAARLLRQREPQLQFVAPMAGDKQRAYFEQLIAE 252 +VA+LPGSRMSELKYN V+F+ AA+LL QR+ LQFVAPMAG+ Q YF +LIA+ Sbjct: 192 PVHAPVVALLPGSRMSELKYNAVAFVAAAKLLLQRDSSLQFVAPMAGEAQHRYFNELIAQ 251 Query: 253 TGAVDLGIHVVSGQSHAAMEAADAVLVASGTASLEVALYKKPMVIAYKMMRASYAIMRHM 312 G D+ I V+ GQSH A+ AADAV+VASGTASLEVAL+KKPMVIAYKMMRAS+ ++RHM Sbjct: 252 AGLQDVQIKVIDGQSHRALAAADAVMVASGTASLEVALFKKPMVIAYKMMRASWYVLRHM 311 Query: 313 NYQPWVGLPNILAREFVVPELLQDAATPQALADALWKQLDDPVHCRNLRQRFTDMHHTLL 372 YQPW+GLPNILA+EF+VPELLQDAATPQALADALW+QL D H L++RFT+MHHTLL Sbjct: 312 GYQPWIGLPNILAQEFLVPELLQDAATPQALADALWQQLQDGAHRDRLQRRFTEMHHTLL 371 Query: 373 RDTANASAQAVCALL 387 RDTA SA+AV L+ Sbjct: 372 RDTAGESARAVLELI 386 >D8IU28.1 D8IU28_HERSS Lipid-A-disaccharide synthase EC=2.4.1.182 Length = 391 Score = 573 bits (1477), Expect = e-161, Method: Compositional matrix adjust. Identities = 281/390 (72%), Positives = 324/390 (83%), Gaps = 4/390 (1%) Query: 6 VASSDNI----SIAMVAGESSGDLLASRLLSGLRPRLPDARLHGIGGPHMAEHGFVSDWP 61 +ASS +I SIA+VAGESSGDLL SRLL+G+R RLP+ RLHGIGG HM GF SDWP Sbjct: 1 MASSADITRRQSIALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFASDWP 60 Query: 62 MDKLTVRGLFEVVPRYRELKGIQNTLRDQLLAERPSVFIGIDYPGFNLGLEQQLRDAGIP 121 MDKLTVRGLFEV+PRYRE+KGIQ+ LRD+LLA+RP VF+G+DYPGFNLGLE+QL+ AGIP Sbjct: 61 MDKLTVRGLFEVIPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIP 120 Query: 122 TMHFIGPQIWAWRGGRIKKIARAVSHMLVIFPFEEEIYRKAGVPVTYVGHPLAEIIPMEP 181 T+HFIGPQIWAWRG RIKKI RAVSHMLVIFPFEE IYR+AGVPVTYVGHPLAE+IP++P Sbjct: 121 TIHFIGPQIWAWRGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQP 180 Query: 182 DQAGARAALGLQQDRRIVAILPGSRMSELKYNTVSFLGAARLLRQREPQLQFVAPMAGDK 241 D GAR L L R+VAILPGSRMSELK N FL AARLL+QR+ QLQFV P+ GD+ Sbjct: 181 DTRGARQRLDLNGPGRVVAILPGSRMSELKQNGAGFLAAARLLKQRDAQLQFVTPIGGDR 240 Query: 242 QRAYFEQLIAETGAVDLGIHVVSGQSHAAMEAADAVLVASGTASLEVALYKKPMVIAYKM 301 Q A F++ I + G DL I V+ GQSH+AMEAADAVLVASGTASLEVALYKKPMVI+YK+ Sbjct: 241 QIAAFQEQIRQGGYEDLDISVIRGQSHSAMEAADAVLVASGTASLEVALYKKPMVISYKV 300 Query: 302 MRASYAIMRHMNYQPWVGLPNILAREFVVPELLQDAATPQALADALWKQLDDPVHCRNLR 361 ASY IMRHM YQPWVGLPNILAREF+VPELLQ ATP+ALADA+W QL+D H + L Sbjct: 301 NWASYQIMRHMAYQPWVGLPNILAREFLVPELLQHQATPEALADAMWFQLEDHAHQQRLA 360 Query: 362 QRFTDMHHTLLRDTANASAQAVCALLDRQR 391 +RF DMH +LLRDT+ SA AVC ++ +R Sbjct: 361 RRFADMHQSLLRDTSRESANAVCEVIGARR 390 >C3X7S5.1 C3X7S5_OXAFO Lipid-A-disaccharide synthase EC=2.4.1.182 Length = 375 Score = 488 bits (1257), Expect = e-136, Method: Compositional matrix adjust. Identities = 234/373 (62%), Positives = 297/373 (79%), Gaps = 1/373 (0%) Query: 16 MVAGESSGDLLASRLLSGLRPRLPDARLHGIGGPHMAEHGFVSDWPMDKLTVRGLFEVVP 75 MVAGE+SGDLL + LLS LRP+LPD +HGIGGP MA++ FVS+WPM+KL+V GLFEV+ Sbjct: 1 MVAGETSGDLLGANLLSALRPQLPDTLMHGIGGPQMAKYDFVSNWPMEKLSVNGLFEVLA 60 Query: 76 RYRELKGIQNTLRDQLLAERPSVFIGIDYPGFNLGLEQQLRDAGIPTMHFIGPQIWAWRG 135 YRE+KGI N LRD LLA+RP VF+GID P FNL LE L+ AGI T+HF+ P +WAWR Sbjct: 61 HYREIKGIHNHLRDHLLAQRPDVFVGIDSPEFNLSLELALKKAGIKTVHFVSPSVWAWRS 120 Query: 136 GRIKKIARAVSHMLVIFPFEEEIYRKAGVPVTYVGHPLAEIIPMEPDQAGARAALGLQQD 195 GRI+KIA AVS +LV+FPFEE IY+KAG+PVTYVGHPLAE IPM PD AR +LGL ++ Sbjct: 121 GRIRKIAEAVSRILVLFPFEEAIYQKAGIPVTYVGHPLAESIPMRPDIDAARTSLGLDRE 180 Query: 196 RRIVAILPGSRMSELKYNTVSFLGAARLLRQREPQLQFVAPMAGDKQRAYFEQLIAETGA 255 + ++ I+PGSRMSELKYN+ +F+ +A++L QR+P +QFV PMAGD+Q YF +L++ Sbjct: 181 KPVITIMPGSRMSELKYNSPAFVESAKILLQRDPTIQFVIPMAGDEQLKYFTKLVSGARL 240 Query: 256 VDLGIHVVSGQSHAAMEAADAVLVASGTASLEVALYKKPMVIAYKMMRASYAIMRHMNYQ 315 DL + +V G SHAA+ AADAVLVASGTA+LEVAL+KKPMVIAYK+MRA++ I RH+ + Sbjct: 241 DDLPLQIVRGHSHAAITAADAVLVASGTATLEVALFKKPMVIAYKLMRATWEIARHI-VK 299 Query: 316 PWVGLPNILAREFVVPELLQDAATPQALADALWKQLDDPVHCRNLRQRFTDMHHTLLRDT 375 P VGLPNILA E +VPELLQ+AAT QALADALW QL D + + L +RF MH++LLR+T Sbjct: 300 PPVGLPNILAGEMIVPELLQNAATGQALADALWFQLTDQANRQRLEERFIAMHYSLLRNT 359 Query: 376 ANASAQAVCALLD 388 A SA A+ +++ Sbjct: 360 AQTSADAILEVMN 372 >C3X1G4.1 C3X1G4_OXAFO Lipid-A-disaccharide synthase EC=2.4.1.182 Length = 380 Score = 487 bits (1254), Expect = e-135, Method: Compositional matrix adjust. Identities = 237/378 (62%), Positives = 297/378 (78%), Gaps = 1/378 (0%) Query: 13 SIAMVAGESSGDLLASRLLSGLRPRLPDARLHGIGGPHMAEHGFVSDWPMDKLTVRGLFE 72 SIAMVAGE+SGDLL LLS LRP+LP+ +HGIGGP MA++ FVS+WPM+KL V GLFE Sbjct: 3 SIAMVAGETSGDLLGETLLSALRPQLPNTLMHGIGGPRMAKYDFVSNWPMEKLAVNGLFE 62 Query: 73 VVPRYRELKGIQNTLRDQLLAERPSVFIGIDYPGFNLGLEQQLRDAGIPTMHFIGPQIWA 132 V+ YRE+KGI+N LRD LLAERP VF+GID P FNL LE L+ GI T+HF+ P +WA Sbjct: 63 VLAHYREIKGIRNHLRDHLLAERPDVFVGIDAPEFNLDLEVALKKKGIKTVHFVSPSVWA 122 Query: 133 WRGGRIKKIARAVSHMLVIFPFEEEIYRKAGVPVTYVGHPLAEIIPMEPDQAGARAALGL 192 WR GRI+KIA AVS +LV+FPFEE IY+KAG+PVT VGHPLAE IPM PD AR +LGL Sbjct: 123 WRSGRIRKIAEAVSRILVLFPFEEAIYQKAGIPVTCVGHPLAEAIPMRPDMNAARDSLGL 182 Query: 193 QQDRRIVAILPGSRMSELKYNTVSFLGAARLLRQREPQLQFVAPMAGDKQRAYFEQLIAE 252 +++ +VAI+PGSRMSELKYN++ F+ AA+LL +R+P +QF+ PMAGD+Q AYF +L E Sbjct: 183 DKEKPVVAIMPGSRMSELKYNSLPFIDAAKLLLKRDPDIQFIIPMAGDEQLAYFTRLATE 242 Query: 253 TGAVDLGIHVVSGQSHAAMEAADAVLVASGTASLEVALYKKPMVIAYKMMRASYAIMRHM 312 L + +V GQSH A+ AADAVLVASGTA+LEVAL+KKPMVIAY++MRA++ I RH+ Sbjct: 243 AHLDKLPLKLVKGQSHTAITAADAVLVASGTATLEVALFKKPMVIAYRLMRATWEIARHI 302 Query: 313 NYQPWVGLPNILAREFVVPELLQDAATPQALADALWKQLDDPVHCRNLRQRFTDMHHTLL 372 +P VGLPNILA E +VPELLQ+AAT +AL++ALW QL D + L +RF MH++LL Sbjct: 303 -VKPPVGLPNILAGEMIVPELLQNAATGKALSEALWFQLTDQANRNRLHERFVAMHYSLL 361 Query: 373 RDTANASAQAVCALLDRQ 390 R+TA ASAQAV ++ Sbjct: 362 RNTAQASAQAVLDVMKEN 379