BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0025.p (388 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IU21.1 D8IU21_HERSS 1-deoxy-D-xylulose 5-phosphate reductoisom... 573 e-161 A4G4S7.1 DXR_HERAR 1-deoxy-D-xylulose 5-phosphate reductoisomera... 566 e-159 A6SZP5.1 DXR_JANMA 1-deoxy-D-xylulose 5-phosphate reductoisomera... 565 e-159 F1W2N1.1 F1W2N1_9BURK 1-deoxy-D-xylulose 5-phosphate reductoisom... 559 e-157 C3X1F7.1 C3X1F7_OXAFO 1-deoxy-D-xylulose 5-phosphate reductoisom... 543 e-152 >D8IU21.1 D8IU21_HERSS 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 390 Score = 573 bits (1477), Expect = e-161, Method: Compositional matrix adjust. Identities = 298/389 (76%), Positives = 329/389 (84%), Gaps = 2/389 (0%) Query: 1 MQAISVLGSTGSIGVSTLDVVGRHPERYRVYALTAHSRVDELAAQCVRFHPQVAVVGTAE 60 MQ+IS+LGSTGSIGVSTLDVV RHP+RYRVYAL+AHSRV ELA QC +F PQVAVVGTA Sbjct: 1 MQSISILGSTGSIGVSTLDVVARHPDRYRVYALSAHSRVAELAQQCAQFRPQVAVVGTAA 60 Query: 61 AAGVLQQKLRAQGLRTEVAYGPQALCDVASAAACDMVMAAIVGAA--PXTLAAARAGKKI 118 AA LQ L A+ ++TEVAYGPQALCD+ASA CDMVMAAIVGAA TLAAARAGKKI Sbjct: 61 AAAELQFLLAARAIKTEVAYGPQALCDIASANGCDMVMAAIVGAAGLASTLAAARAGKKI 120 Query: 119 LLANKEALVMSGQLLIDAVAEHKATLLPIDSEHNAIFQCLPHDFRRSLDDGGIAKILLTA 178 LLANKEALV+SGQLL+DAVA H A+LLPIDSEHNAIFQCLP + RS+ G+ KILLTA Sbjct: 121 LLANKEALVISGQLLMDAVAAHGASLLPIDSEHNAIFQCLPPGYTRSMSAHGVEKILLTA 180 Query: 179 SGGPFLKRAVDTLDSVTPDEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAPADR 238 SGGPFL R V TLD+VT +EAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAPAD+ Sbjct: 181 SGGPFLTRDVGTLDTVTVEEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAPADK 240 Query: 239 IEVMIHPQSVIHSMVSYIDGSVLAQLGNPDMRTPIANAMAYPERIASGVAQLDLTQIGQL 298 IEV+IHPQSVIHSMVSY DGSVLAQLGNPDMRTPIANA+AYPERIASGVA LDL QI QL Sbjct: 241 IEVVIHPQSVIHSMVSYADGSVLAQLGNPDMRTPIANALAYPERIASGVAPLDLAQIAQL 300 Query: 299 FFERPDLARFPCLKLAYDALHAGGSSAAILNAANEVAVEAFLNQEIGFRMIDQVIARVMD 358 F PD RFPCLKLAYDAL AGG+ AAILNAANEVAV+AFL + IGF I +I VM Sbjct: 301 SFSEPDFQRFPCLKLAYDALRAGGTLAAILNAANEVAVQAFLGRRIGFGKIAPLIDEVMS 360 Query: 359 KLPHGTVTDIDALIEQDKIARSVAQSCLT 387 +P+ DIDAL+EQD+ ARS A+ ++ Sbjct: 361 AIPNRQADDIDALLEQDRQARSHAEHLIS 389 >A4G4S7.1 DXR_HERAR 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 391 Score = 567 bits (1460), Expect = e-159, Method: Compositional matrix adjust. Identities = 289/389 (74%), Positives = 321/389 (82%), Gaps = 5/389 (1%) Query: 1 MQAISVLGSTGSIGVSTLDVVGRHPERYRVYALTAHSRVDELAAQCVRFHPQVAVVGTAE 60 MQ I++LGSTGSIGVSTLDVV RHP+RYRV+ALTA ++V+ELAAQC +FHP VAVVG+AE Sbjct: 1 MQHITILGSTGSIGVSTLDVVARHPDRYRVHALTAQNKVEELAAQCAQFHPDVAVVGSAE 60 Query: 61 AAGVLQQKLRAQGLRTEVAYGPQALCDVASAAACDMVMAAIVGAA--PXTLAAARAGKKI 118 AA LQ L GL+T+V YG ALC VASA CD VMAAIVG A TLAAARAGKKI Sbjct: 61 AAQKLQVLLNGMGLQTQVEYGAAALCTVASAPECDCVMAAIVGGAGLAPTLAAARAGKKI 120 Query: 119 LLANKEALVMSGQLLIDAVAEHKATLLPIDSEHNAIFQCLP---HDFRRSLDDGGIAKIL 175 LLANKEALVMSG LL++AVA A L+PIDSEHNAIFQC+P H + + GI KIL Sbjct: 121 LLANKEALVMSGPLLMEAVAASGAILMPIDSEHNAIFQCMPATYHQQQLTPAQHGIEKIL 180 Query: 176 LTASGGPFLKRAVDTLDSVTPDEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAP 235 LTASGGPFL RA+DTLD VT EA+AHPKWVMGRKISVDSATMMNKGLEVIEAHWLFG P Sbjct: 181 LTASGGPFLNRALDTLDQVTCAEAIAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGVP 240 Query: 236 ADRIEVMIHPQSVIHSMVSYIDGSVLAQLGNPDMRTPIANAMAYPERIASGVAQLDLTQI 295 ADRIEV+IHPQSV+HSMVSYIDGSVLAQLGNPDMRTPIA+AMAYPERI SGVA +DL +I Sbjct: 241 ADRIEVVIHPQSVVHSMVSYIDGSVLAQLGNPDMRTPIAHAMAYPERIDSGVAPIDLIKI 300 Query: 296 GQLFFERPDLARFPCLKLAYDALHAGGSSAAILNAANEVAVEAFLNQEIGFRMIDQVIAR 355 QL FE PDL RFPCLKLAYDAL AGGS+ AI+NAANE+AV+AFL+ IGFR IDQ+IAR Sbjct: 301 AQLTFEHPDLLRFPCLKLAYDALQAGGSAPAIMNAANEIAVQAFLDGRIGFRAIDQLIAR 360 Query: 356 VMDKLPHGTVTDIDALIEQDKIARSVAQS 384 VM LP VTDID + EQD+ AR A S Sbjct: 361 VMAALPSSPVTDIDTVFEQDRRARDTAAS 389 >A6SZP5.1 DXR_JANMA 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 390 Score = 565 bits (1456), Expect = e-159, Method: Compositional matrix adjust. Identities = 280/386 (72%), Positives = 322/386 (83%), Gaps = 2/386 (0%) Query: 1 MQAISVLGSTGSIGVSTLDVVGRHPERYRVYALTAHSRVDELAAQCVRFHPQVAVVGTAE 60 MQ I++LGSTGS+GVSTLDV+ RHP+RY VYALTA S+V+ELA QC RF PQVAVVG+AE Sbjct: 1 MQQITILGSTGSVGVSTLDVIARHPDRYSVYALTAQSKVEELAQQCARFKPQVAVVGSAE 60 Query: 61 AAGVLQQKLRAQGLRTEVAYGPQALCDVASAAACDMVMAAIVGAA--PXTLAAARAGKKI 118 AA LQ L AQGL T+V YG ALC VASA CD VMAAIVGAA TLAAAR+GK++ Sbjct: 61 AAKKLQVLLDAQGLHTQVGYGEAALCAVASAPECDSVMAAIVGAAGLAPTLAAARSGKRV 120 Query: 119 LLANKEALVMSGQLLIDAVAEHKATLLPIDSEHNAIFQCLPHDFRRSLDDGGIAKILLTA 178 LLANKEALVMSG LL++AVA A L+PIDSEHNAIFQC+P +R+ G+ KILLTA Sbjct: 121 LLANKEALVMSGPLLMEAVAASGAILMPIDSEHNAIFQCMPATCQRTPLAHGVEKILLTA 180 Query: 179 SGGPFLKRAVDTLDSVTPDEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAPADR 238 SGGPFLKR V+TLD V+ EAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLF PA+R Sbjct: 181 SGGPFLKRDVNTLDQVSWQEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFDLPAER 240 Query: 239 IEVMIHPQSVIHSMVSYIDGSVLAQLGNPDMRTPIANAMAYPERIASGVAQLDLTQIGQL 298 IEV+IHPQSV+HSMVSY+DGSVLAQLGNPDMRTPIA+A+AYPERI+SGV +DL QI QL Sbjct: 241 IEVVIHPQSVVHSMVSYVDGSVLAQLGNPDMRTPIAHALAYPERISSGVPPIDLIQIAQL 300 Query: 299 FFERPDLARFPCLKLAYDALHAGGSSAAILNAANEVAVEAFLNQEIGFRMIDQVIARVMD 358 FERPD RFPCLKLAYDAL AGGS+ AI+NAANE+AV+AFL+ IGFR IDQ+IARVMD Sbjct: 301 SFERPDFLRFPCLKLAYDALQAGGSAPAIMNAANEIAVQAFLDSRIGFRAIDQLIARVMD 360 Query: 359 KLPHGTVTDIDALIEQDKIARSVAQS 384 +P +TDI+++ QD+ AR +A S Sbjct: 361 VMPSVAITDIESVFAQDRCARELANS 386 >F1W2N1.1 F1W2N1_9BURK 1-deoxy-D-xylulose 5-phosphate reductoisomerase Length = 390 Score = 559 bits (1441), Expect = e-157, Method: Compositional matrix adjust. Identities = 287/389 (73%), Positives = 327/389 (84%), Gaps = 2/389 (0%) Query: 1 MQAISVLGSTGSIGVSTLDVVGRHPERYRVYALTAHSRVDELAAQCVRFHPQVAVVGTAE 60 MQ I++LG+TGSIG+STLDVV RHP+RYR+YALTAH++V ELAA C RF P VAVVG+A Sbjct: 1 MQNITILGATGSIGMSTLDVVARHPDRYRIYALTAHTKVVELAALCARFRPDVAVVGSAA 60 Query: 61 AAGVLQQKLRAQGLRTEVAYGPQALCDVASAAACDMVMAAIVGAA--PXTLAAARAGKKI 118 AA L L+A G+ TEV+YG ALC VAS +ACD VMAAIVGAA TLAAARAGKKI Sbjct: 61 AAQELTALLKADGIATEVSYGEDALCSVASGSACDTVMAAIVGAAGLAPTLAAARAGKKI 120 Query: 119 LLANKEALVMSGQLLIDAVAEHKATLLPIDSEHNAIFQCLPHDFRRSLDDGGIAKILLTA 178 LLANKEALVMSGQL +DA+A ATLLPIDSEHNA+FQCLP ++R+LD GIA+ILLTA Sbjct: 121 LLANKEALVMSGQLFMDAIAASGATLLPIDSEHNAVFQCLPQPYQRNLDHHGIARILLTA 180 Query: 179 SGGPFLKRAVDTLDSVTPDEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAPADR 238 SGGPFL+RAV+TLD VTPDEAVAHP WVMGRKISVDSATMMNKGLEVIEAHWLFGA +R Sbjct: 181 SGGPFLERAVETLDQVTPDEAVAHPNWVMGRKISVDSATMMNKGLEVIEAHWLFGASHER 240 Query: 239 IEVMIHPQSVIHSMVSYIDGSVLAQLGNPDMRTPIANAMAYPERIASGVAQLDLTQIGQL 298 IEV+IHPQSVIHSMVSY+DG+VLAQLGNPDMRTPIA+A+AYPERI SGVA LDLT++ +L Sbjct: 241 IEVVIHPQSVIHSMVSYLDGTVLAQLGNPDMRTPIAHALAYPERIVSGVAPLDLTRLAKL 300 Query: 299 FFERPDLARFPCLKLAYDALHAGGSSAAILNAANEVAVEAFLNQEIGFRMIDQVIARVMD 358 F +PDL RFPCLKLAYDAL GGS+ A+LNAANEVAVEAFL+ IGFR IDQ+IARVM Sbjct: 301 EFRQPDLLRFPCLKLAYDALSTGGSAPAVLNAANEVAVEAFLDGRIGFRQIDQLIARVMH 360 Query: 359 KLPHGTVTDIDALIEQDKIARSVAQSCLT 387 V DI L+EQD+ AR +A + LT Sbjct: 361 AASFEAVPDIAGLLEQDRHARQLANAFLT 389 >C3X1F7.1 C3X1F7_OXAFO 1-deoxy-D-xylulose 5-phosphate reductoisomerase EC=1.1.1.267 Length = 395 Score = 543 bits (1399), Expect = e-152, Method: Compositional matrix adjust. Identities = 272/388 (70%), Positives = 322/388 (82%), Gaps = 3/388 (0%) Query: 2 QAISVLGSTGSIGVSTLDVVGRHPERYRVYALTAHSRVDELAAQCVRFHPQVAVVGTAEA 61 Q I+VLGSTGSIGVSTLDV+ RHPE+Y V+ALTA+SRV EL QC RFHP++AVVGTA A Sbjct: 6 QRITVLGSTGSIGVSTLDVLVRHPEQYVVHALTANSRVGELLRQCERFHPEIAVVGTAAA 65 Query: 62 AGVLQQKLRAQGLRTEVAYGPQALCDVASAAACDMVMAAIVGAAPXTLAAARAG--KKIL 119 A VL++ LR++G+ TEV YG +ALC+VAS++ CD VMAAIVGAA A A A KK++ Sbjct: 66 ASVLERNLRSKGIATEVLYGEKALCEVASSSQCDAVMAAIVGAAGLAPALAAARAGKKVM 125 Query: 120 LANKEALVMSGQLLIDAVAEHKATLLPIDSEHNAIFQCLPHDFRRSLDDGGIAKILLTAS 179 LANKEALVMSGQL ID VA ATLLPIDSEHNAIFQCLP+ +R G++KILLTAS Sbjct: 126 LANKEALVMSGQLFIDTVAASGATLLPIDSEHNAIFQCLPYRHKRFPHRHGVSKILLTAS 185 Query: 180 GGPFLKRAVDTLDSVTPDEAVAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGAPADRI 239 GGPFL R VDTLDSVTP++A+AHPKWVMGRKISVDSATMMNKGLEVIEAHWLFG PA +I Sbjct: 186 GGPFLHRPVDTLDSVTPEQAIAHPKWVMGRKISVDSATMMNKGLEVIEAHWLFGIPASQI 245 Query: 240 EVMIHPQSVIHSMVSYIDGSVLAQLGNPDMRTPIANAMAYPERIASGVAQLDLTQIGQLF 299 EV+IHPQSVIHSMVSY+DGSV+AQLGNPDMR PIA+A+AYPER+ SGV LDLT+IG L Sbjct: 246 EVVIHPQSVIHSMVSYVDGSVIAQLGNPDMRIPIAHALAYPERMTSGVTPLDLTRIGTLQ 305 Query: 300 FERPDLARFPCLKLAYDALHAGGSSAAILNAANEVAVEAFLNQEIGFRMIDQVIARVMDK 359 FE PD RFPCL+LAY+AL GG++ AILNAANEVAV+AFL Q I FR ID V+ARV+DK Sbjct: 306 FESPDFVRFPCLRLAYEALKTGGATPAILNAANEVAVQAFLEQRISFRRIDDVVARVLDK 365 Query: 360 LP-HGTVTDIDALIEQDKIARSVAQSCL 386 +P ++T ID+++ D+ AR+VA + + Sbjct: 366 VPTESSITGIDSVLMHDRAARTVATNLI 393