BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0015.p (453 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWE4.1 D8IWE4_HERSS Permease of the major facilitator superfam... 650 0.0 F1W052.1 F1W052_9BURK Putative transporter protein 641 0.0 E6UXF6.1 E6UXF6_VARPD General substrate transporter 639 0.0 A6T1D4.1 A6T1D4_JANMA Transporter of the MFS superfamily 637 0.0 C5CWQ2.1 C5CWQ2_VARPS General substrate transporter 634 e-180 >D8IWE4.1 D8IWE4_HERSS Permease of the major facilitator superfamily protein Length = 447 Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/451 (73%), Positives = 392/451 (86%), Gaps = 6/451 (1%) Query: 3 MASTHIHHPEVPGKFSANTPVGGSDNVNNAKSDHPVIAPGDIAIGVVIGRASEYFDFFVY 62 MAST IH+ + G+ +G + DH I PG+IA+GVVIGRASEYFDFFVY Sbjct: 1 MASTSIHNGQGSGE------LGPHSTHPSTSHDHGKIEPGEIAVGVVIGRASEYFDFFVY 54 Query: 63 AIASVLVFPTIFFPFEQRLEGTLYSFTIFAFAFLARPFGTILFMAIQRKLGREVKLTLAL 122 A+ASVLVFP +FFP E +LEGTLY+F IFAFAFLARP GT +FMAIQ+ GREVKLTLAL Sbjct: 55 ALASVLVFPAVFFPNEPKLEGTLYAFVIFAFAFLARPIGTTIFMAIQKHYGREVKLTLAL 114 Query: 123 FLLGLSTAGIAFLPTYEHLGFTAIVLLSVLRIGQGLALGGSWDGLPSLLALNVPKNKRGW 182 F+LG STAGIA LPT+EH+G AI+LLS+LR+GQGLALGG+WDGLPSLLA+N P++KRGW Sbjct: 115 FMLGFSTAGIALLPTFEHIGVWAIILLSLLRVGQGLALGGAWDGLPSLLAMNAPQHKRGW 174 Query: 183 YAMLGQLGAPVGFIVAGLVFAYLIGNLSSDDFLEWGWRYPFYVAFAINVVALFARLRLVA 242 YA LGQLGAP+GF+VA +FAY++ +L++ DFLEWGWRYPFYVAFAINVVALF+RLRLV+ Sbjct: 175 YAALGQLGAPLGFVVAASLFAYMLSSLTTADFLEWGWRYPFYVAFAINVVALFSRLRLVS 234 Query: 243 SDEYAQLLKERELEPTGVVDITRTQGRNLIIGALAALASYALFHLVSVFPLSWISLYSMR 302 + EYA+LL ERELEP GVV++ TQGRN+IIGALAALASYALFHLV+VFPLSWI LYS+R Sbjct: 235 APEYAKLLDERELEPAGVVELATTQGRNIIIGALAALASYALFHLVTVFPLSWIKLYSLR 294 Query: 303 SMSDFLMVQVFGAVLMMVGIVLSGPIADRFGRRTTLGALAVLIAVLSGFVPTLINGGDTG 362 +DFL+VQ++G ++M VGIV+SG IADRFGRR TLG++A+LIA+LS FVPTL+NGG+ G Sbjct: 295 EATDFLVVQIWGGLIMAVGIVISGLIADRFGRRNTLGSMALLIAILSAFVPTLMNGGEAG 354 Query: 363 QDIFILVGFALLGLSYGQAAGAVTANFPAKYRYTGAALTSDLAWLVGAGFAPLVALGLSA 422 Q+ FIL+GFALLGLSYGQAAGAVTANF A+YRYTGAALTSDLAWLVGAGFAPLVALGLSA Sbjct: 355 QNTFILIGFALLGLSYGQAAGAVTANFKARYRYTGAALTSDLAWLVGAGFAPLVALGLSA 414 Query: 423 HFGLAYVSIYLLSGAVCSLAALSVNRALDIR 453 HFG+AYVS YLLSGAV SLAALS+NRAL+ R Sbjct: 415 HFGMAYVSFYLLSGAVGSLAALSLNRALEAR 445 >F1W052.1 F1W052_9BURK Putative transporter protein Length = 449 Score = 641 bits (1653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/447 (72%), Positives = 388/447 (86%) Query: 7 HIHHPEVPGKFSANTPVGGSDNVNNAKSDHPVIAPGDIAIGVVIGRASEYFDFFVYAIAS 66 HI + G A + ++A DH VI P +IA+GV+IGRASEYFDFFVYA+AS Sbjct: 2 HIQQGQHTGTAGAAQTHSSVRDRHHANHDHSVIKPAEIAVGVIIGRASEYFDFFVYAMAS 61 Query: 67 VLVFPTIFFPFEQRLEGTLYSFTIFAFAFLARPFGTILFMAIQRKLGREVKLTLALFLLG 126 VLVFP++FFPF L+G LY+F IF+FAFLARP GT+LFM IQR+ GREVKLTLALF+LG Sbjct: 62 VLVFPSVFFPFASPLDGALYAFMIFSFAFLARPLGTVLFMEIQRRFGREVKLTLALFILG 121 Query: 127 LSTAGIAFLPTYEHLGFTAIVLLSVLRIGQGLALGGSWDGLPSLLALNVPKNKRGWYAML 186 +STAGIAFLP Y LG +IV+LS+LRIGQG+A+GGSWDGLPSLLALN P +RGWYAML Sbjct: 122 ISTAGIAFLPGYASLGSASIVVLSLLRIGQGIAIGGSWDGLPSLLALNAPPERRGWYAML 181 Query: 187 GQLGAPVGFIVAGLVFAYLIGNLSSDDFLEWGWRYPFYVAFAINVVALFARLRLVASDEY 246 GQLGAP+GF+VAG +FAYL+ NL+S +F++WGWR+PFY AFAINVVALFARLRLV+++EY Sbjct: 182 GQLGAPIGFMVAGGLFAYLLTNLTSAEFMDWGWRFPFYAAFAINVVALFARLRLVSTNEY 241 Query: 247 AQLLKERELEPTGVVDITRTQGRNLIIGALAALASYALFHLVSVFPLSWISLYSMRSMSD 306 A LL+ERELEPTGVV++TR+QGRN++IGALAALASYALFHLV+VFPLSWISL+S+R +S+ Sbjct: 242 ANLLEERELEPTGVVELTRSQGRNIVIGALAALASYALFHLVTVFPLSWISLHSIRPVSE 301 Query: 307 FLMVQVFGAVLMMVGIVLSGPIADRFGRRTTLGALAVLIAVLSGFVPTLINGGDTGQDIF 366 FL +Q+ GA LM +G+V+SG IADR GRRTTLGA AVLIA+LS FVP L+NGG G++IF Sbjct: 302 FLEIQILGAALMALGVVVSGLIADRVGRRTTLGACAVLIAILSAFVPMLMNGGVMGENIF 361 Query: 367 ILVGFALLGLSYGQAAGAVTANFPAKYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGL 426 ILVGF+LLGLSYGQAAGAVTANF ++YRYTGAALTSDL+WLVGAGFAPLVAL L++HFG+ Sbjct: 362 ILVGFSLLGLSYGQAAGAVTANFASRYRYTGAALTSDLSWLVGAGFAPLVALALASHFGM 421 Query: 427 AYVSIYLLSGAVCSLAALSVNRALDIR 453 AYV +YL+SGAVCSLAAL +NRAL+IR Sbjct: 422 AYVGLYLVSGAVCSLAALRLNRALEIR 448 >E6UXF6.1 E6UXF6_VARPD General substrate transporter Length = 450 Score = 639 bits (1649), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/431 (74%), Positives = 371/431 (86%) Query: 20 NTPVGGSDNVNNAKSDHPVIAPGDIAIGVVIGRASEYFDFFVYAIASVLVFPTIFFPFEQ 79 NT G+ + +DH IAPG+IA+GVVIGRASEYFDFFVY IASVLVFP +FFPFEQ Sbjct: 17 NTSGNGAGPSQSGGADHSHIAPGEIAVGVVIGRASEYFDFFVYGIASVLVFPYVFFPFEQ 76 Query: 80 RLEGTLYSFTIFAFAFLARPFGTILFMAIQRKLGREVKLTLALFLLGLSTAGIAFLPTYE 139 RLEG LY+F +F+FAF+ARPFGT++ MAIQR+ GRE KLT+ALFLLG STAGIAFLP YE Sbjct: 77 RLEGILYAFVVFSFAFIARPFGTVISMAIQRRFGRETKLTIALFLLGTSTAGIAFLPGYE 136 Query: 140 HLGFTAIVLLSVLRIGQGLALGGSWDGLPSLLALNVPKNKRGWYAMLGQLGAPVGFIVAG 199 LGFTAIVLLSV R QGLALGGSWDGLPSLLALN P N+RGWYAMLGQLGAP+GF +A Sbjct: 137 SLGFTAIVLLSVFRFCQGLALGGSWDGLPSLLALNAPPNRRGWYAMLGQLGAPIGFFIAS 196 Query: 200 LVFAYLIGNLSSDDFLEWGWRYPFYVAFAINVVALFARLRLVASDEYAQLLKERELEPTG 259 +FAYL +LS +FL+WGWRY FYVAFAINVVALFARLRLVA++EY++LL+EREL+PT Sbjct: 197 ALFAYLYASLSIKEFLDWGWRYTFYVAFAINVVALFARLRLVATEEYSRLLEERELQPTS 256 Query: 260 VVDITRTQGRNLIIGALAALASYALFHLVSVFPLSWISLYSMRSMSDFLMVQVFGAVLMM 319 VV++TR+QG NL+IGA AALASYALFHL++VFPLSWI+LYS +S+++FL+VQ+ GAV Sbjct: 257 VVELTRSQGANLLIGAFAALASYALFHLITVFPLSWITLYSDQSITEFLIVQMIGAVFCA 316 Query: 320 VGIVLSGPIADRFGRRTTLGALAVLIAVLSGFVPTLINGGDTGQDIFILVGFALLGLSYG 379 GIV SG IADR GRR TLG LA LIAV SGF PTL++GG GQD+FIL+GF LLGLSYG Sbjct: 317 GGIVASGLIADRVGRRFTLGGLAALIAVFSGFAPTLLDGGRIGQDVFILLGFVLLGLSYG 376 Query: 380 QAAGAVTANFPAKYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGLAYVSIYLLSGAVC 439 QAAGAVT+NF KYRYTGAALT+DLAWL+GA FAPLVALGLSA+FGLAYVS+YLLSGA Sbjct: 377 QAAGAVTSNFEPKYRYTGAALTADLAWLIGAAFAPLVALGLSANFGLAYVSVYLLSGAAG 436 Query: 440 SLAALSVNRAL 450 +LAAL +NRAL Sbjct: 437 TLAALGLNRAL 447 >A6T1D4.1 A6T1D4_JANMA Transporter of the MFS superfamily Length = 447 Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/451 (74%), Positives = 384/451 (85%), Gaps = 5/451 (1%) Query: 3 MASTHIHHPEVPGKFSANTPVGGSDNVNNAKSDHPVIAPGDIAIGVVIGRASEYFDFFVY 62 MA+T+ +P +P G + N + H IAPG+IAIGVVIGRASEYFDFFVY Sbjct: 1 MATTY--DTGLPDDSKLASP-GNGPRLVNTRGGH--IAPGEIAIGVVIGRASEYFDFFVY 55 Query: 63 AIASVLVFPTIFFPFEQRLEGTLYSFTIFAFAFLARPFGTILFMAIQRKLGREVKLTLAL 122 AIASVLVFP++FFPF Q LEGTLYSFT+FAFAFLARP GT+ FMAIQR+ RE KLTLAL Sbjct: 56 AIASVLVFPSVFFPFAQPLEGTLYSFTVFAFAFLARPLGTVAFMAIQRRFSREAKLTLAL 115 Query: 123 FLLGLSTAGIAFLPTYEHLGFTAIVLLSVLRIGQGLALGGSWDGLPSLLALNVPKNKRGW 182 FLLG STAGIAFLP+Y LG +AI+ LS+LRIGQG+ALGGSWDGLPSLLALN P+N+RGW Sbjct: 116 FLLGFSTAGIAFLPSYAQLGMSAILFLSLLRIGQGIALGGSWDGLPSLLALNAPQNRRGW 175 Query: 183 YAMLGQLGAPVGFIVAGLVFAYLIGNLSSDDFLEWGWRYPFYVAFAINVVALFARLRLVA 242 YAMLGQLGAPVGF++A +F++L+ LS DFLEWGWRYPFYVAFAINVVALFARLRLV+ Sbjct: 176 YAMLGQLGAPVGFLIAAGLFSFLLSELSRADFLEWGWRYPFYVAFAINVVALFARLRLVS 235 Query: 243 SDEYAQLLKERELEPTGVVDITRTQGRNLIIGALAALASYALFHLVSVFPLSWISLYSMR 302 + EY++LL E+ELEP +I + QGRNLIIGALAALASYALFHLV+VFPLSWISLYS R Sbjct: 236 TPEYSRLLDEQELEPVSATEIVQKQGRNLIIGALAALASYALFHLVTVFPLSWISLYSDR 295 Query: 303 SMSDFLMVQVFGAVLMMVGIVLSGPIADRFGRRTTLGALAVLIAVLSGFVPTLINGGDTG 362 S+S FL VQ+ GA L VG+V+SG IADRFGRRTTLG LA LIA+ SGFVP L+NGG G Sbjct: 296 SISAFLHVQMMGAALAAVGVVISGLIADRFGRRTTLGTLACLIAIFSGFVPMLLNGGTRG 355 Query: 363 QDIFILVGFALLGLSYGQAAGAVTANFPAKYRYTGAALTSDLAWLVGAGFAPLVALGLSA 422 +D+FIL+GFALLGLSYGQAAGAV+ANF AKYRYTGAALTSDLAWLVGA FAPLVALGLSA Sbjct: 356 EDLFILIGFALLGLSYGQAAGAVSANFHAKYRYTGAALTSDLAWLVGAAFAPLVALGLSA 415 Query: 423 HFGLAYVSIYLLSGAVCSLAALSVNRALDIR 453 HFGL YVS+YLLSGAV SLAALS+NRAL+I+ Sbjct: 416 HFGLGYVSLYLLSGAVGSLAALSLNRALEIK 446 >C5CWQ2.1 C5CWQ2_VARPS General substrate transporter Length = 446 Score = 634 bits (1636), Expect = e-180, Method: Compositional matrix adjust. Identities = 316/425 (74%), Positives = 367/425 (86%) Query: 26 SDNVNNAKSDHPVIAPGDIAIGVVIGRASEYFDFFVYAIASVLVFPTIFFPFEQRLEGTL 85 S+N +H IAPG+IA+GV+IGRASEYFDFFVY IASVLVFP +FFPFE RLEGTL Sbjct: 19 SENAARQGDEHSHIAPGEIAVGVIIGRASEYFDFFVYGIASVLVFPAVFFPFEARLEGTL 78 Query: 86 YSFTIFAFAFLARPFGTILFMAIQRKLGREVKLTLALFLLGLSTAGIAFLPTYEHLGFTA 145 Y+F +F+FAFLARPFGT++ MAIQR+ GRE KLT+ALF+LG STAGIAFLP Y LGFT+ Sbjct: 79 YAFVVFSFAFLARPFGTVISMAIQRRFGREAKLTIALFVLGTSTAGIAFLPGYASLGFTS 138 Query: 146 IVLLSVLRIGQGLALGGSWDGLPSLLALNVPKNKRGWYAMLGQLGAPVGFIVAGLVFAYL 205 IVLLSV R QGLALGGSWDGLPSLLALN P+N+RGWYAMLGQLGAP+GF VA +FAYL Sbjct: 139 IVLLSVFRFAQGLALGGSWDGLPSLLALNAPENRRGWYAMLGQLGAPLGFFVASALFAYL 198 Query: 206 IGNLSSDDFLEWGWRYPFYVAFAINVVALFARLRLVASDEYAQLLKERELEPTGVVDITR 265 NL DFL+WGWRY FYVAFAINVVALFARLRLVA++EY++LL+EREL+PT VV++ R Sbjct: 199 YANLPLKDFLDWGWRYTFYVAFAINVVALFARLRLVATEEYSRLLEERELQPTSVVELAR 258 Query: 266 TQGRNLIIGALAALASYALFHLVSVFPLSWISLYSMRSMSDFLMVQVFGAVLMMVGIVLS 325 +QG NL+IGA AALASYALFHL++VFPLSWI+LYS +S+++FL+VQ+ GAV GIV S Sbjct: 259 SQGANLLIGAFAALASYALFHLITVFPLSWITLYSDQSITEFLVVQMIGAVFCAGGIVAS 318 Query: 326 GPIADRFGRRTTLGALAVLIAVLSGFVPTLINGGDTGQDIFILVGFALLGLSYGQAAGAV 385 G +ADR GRR TLG LA +IAV SGF PTL++GG GQDIFIL+GF LLGLSYGQAAGAV Sbjct: 319 GVVADRVGRRFTLGGLAAMIAVFSGFAPTLLDGGRLGQDIFILLGFVLLGLSYGQAAGAV 378 Query: 386 TANFPAKYRYTGAALTSDLAWLVGAGFAPLVALGLSAHFGLAYVSIYLLSGAVCSLAALS 445 T+NF KYRYTGAALT+DLAWL+GA FAPLVALGLSA+FGLAYVS+YLLSGAV +LAAL Sbjct: 379 TSNFEPKYRYTGAALTADLAWLIGAAFAPLVALGLSANFGLAYVSVYLLSGAVGTLAALG 438 Query: 446 VNRAL 450 +NRAL Sbjct: 439 LNRAL 443