BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0218.p (298 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value XF2283 [R] COG0491 Zn-dependent hydrolases, including glyoxylase... 339 5e-93 PA0057 [R] COG0491 Zn-dependent hydrolases, including glyoxylase... 315 7e-86 YPO0800 [R] COG0491 Zn-dependent hydrolases, including glyoxylas... 315 1e-85 VCA1049 [R] COG0491 Zn-dependent hydrolases, including glyoxylas... 231 1e-60 VCA0900 [R] COG0491 Zn-dependent hydrolases, including glyoxylas... 207 3e-53 >XF2283 [R] COG0491 Zn-dependent hydrolases, including glyoxylases Xfa Xylella fastidiosa 9a5c Length = 317 Score = 339 bits (869), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 153/265 (57%), Positives = 203/265 (76%) Query: 34 LKLDAYNPGDKALFPVSSVLVTGKQDAILVDAQFGRTQAEQVVEKIRASGKKLVAVYISH 93 L ++ +N G++++F VSSVLVTG DAIL+D QF A Q+VEKI+ASGK+L A+YISH Sbjct: 52 LNVEVFNLGERSMFAVSSVLVTGTADAILIDTQFSAADARQLVEKIKASGKRLKAIYISH 111 Query: 94 GDPDYYFGLDTIKAAYPDVKILATPQTVAHIKETVAQKLAFWGPKLGADAPTQTIVPDVL 153 GDPDYYFGLD++ AA+P+ K+LATPQT+AHI+ + KL W P+LG DAP Q ++P+ + Sbjct: 112 GDPDYYFGLDSVHAAFPEAKVLATPQTIAHIQASKDAKLKLWAPQLGQDAPKQILIPEPM 171 Query: 154 DGNTLTLEGKKLQVIGLDGPQPERSFVWIPSIGAVVGGVVVNGSEHIWMADTQGAQSHKD 213 G+ L LEG++L++IG+DGP P+R+FVWIPS V GG+ V G++H+WMADTQ QSH + Sbjct: 172 QGDQLVLEGQELRIIGMDGPTPDRTFVWIPSSRTVAGGISVMGAQHVWMADTQTPQSHIE 231 Query: 214 WLGTLARIEKLKPRIVIPGHYAAGAPMTIASVKYTRDYIKAFDAETAKAVDSTALIAAMK 273 WL L RI+ + P++V+PGH+ GA + + SV +T DYI+AFD ETAKA DS ALIAAMK Sbjct: 232 WLAVLDRIKSMDPKVVVPGHFLPGASLDVRSVTFTADYIRAFDEETAKAKDSAALIAAMK 291 Query: 274 ARYPAPTNLSVLELSAKVAKGEIKW 298 RYP LELSAKVAKGE++W Sbjct: 292 RRYPGLGGEGSLELSAKVAKGEMEW 316 >PA0057 [R] COG0491 Zn-dependent hydrolases, including glyoxylases Pae Pseudomonas aeruginosa Length = 295 Score = 315 bits (807), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 150/271 (55%), Positives = 196/271 (72%) Query: 28 AASDNVLKLDAYNPGDKALFPVSSVLVTGKQDAILVDAQFGRTQAEQVVEKIRASGKKLV 87 AAS L+L+ YNPG+KA+F VSS L+ G+++A+L+DAQF R AEQ+V++I+ASGK L Sbjct: 24 AASAEPLRLEVYNPGEKAIFAVSSELLVGQREAMLIDAQFSRADAEQLVKRIQASGKTLS 83 Query: 88 AVYISHGDPDYYFGLDTIKAAYPDVKILATPQTVAHIKETVAQKLAFWGPKLGADAPTQT 147 +YISHGDPD+YFGLD +KAA+P+ KILAT QTVAHI+ T KLA+WGP L +APT Sbjct: 84 TIYISHGDPDFYFGLDVLKAAFPEAKILATAQTVAHIQATKDAKLAYWGPILKDNAPTSL 143 Query: 148 IVPDVLDGNTLTLEGKKLQVIGLDGPQPERSFVWIPSIGAVVGGVVVNGSEHIWMADTQG 207 +VP+ L G+ L LEG L+V+ L GP P+R+ +WIPS+ VVGGV+V H+W ADTQ Sbjct: 144 VVPEPLKGDQLKLEGHALKVVDLKGPSPDRTVLWIPSLKTVVGGVLVESGSHVWTADTQT 203 Query: 208 AQSHKDWLGTLARIEKLKPRIVIPGHYAAGAPMTIASVKYTRDYIKAFDAETAKAVDSTA 267 S + W+ L RIE L+PR V+PGH+ P + V++TRDY+KA +AE KA DS A Sbjct: 204 QASRQAWVAMLDRIEALQPRRVVPGHFTGEEPKGLDGVRFTRDYLKALEAELPKARDSAA 263 Query: 268 LIAAMKARYPAPTNLSVLELSAKVAKGEIKW 298 L+ AMK RYP LELSAKV KGE++W Sbjct: 264 LVEAMKRRYPNLPGEEGLELSAKVLKGEMQW 294 >YPO0800 [R] COG0491 Zn-dependent hydrolases, including glyoxylases Ype Yersinia pestis Length = 295 Score = 315 bits (806), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 142/265 (53%), Positives = 195/265 (73%) Query: 34 LKLDAYNPGDKALFPVSSVLVTGKQDAILVDAQFGRTQAEQVVEKIRASGKKLVAVYISH 93 LK++ YNPG+K++FPVSS +++GK + +L+DAQF R AE +V+KI+ SGKKL +YIS Sbjct: 29 LKMEVYNPGEKSIFPVSSEIISGKNEVVLIDAQFQRNDAEALVKKIQQSGKKLTTIYISQ 88 Query: 94 GDPDYYFGLDTIKAAYPDVKILATPQTVAHIKETVAQKLAFWGPKLGADAPTQTIVPDVL 153 DPD+YFGLD I A+P K++ATPQT+ IK T K+A+WGP L +APT I+P L Sbjct: 89 ADPDFYFGLDVIAKAFPQAKVIATPQTIEEIKATKDGKMAYWGPILKENAPTAVIIPQPL 148 Query: 154 DGNTLTLEGKKLQVIGLDGPQPERSFVWIPSIGAVVGGVVVNGSEHIWMADTQGAQSHKD 213 G + T++G++++V GLDGP PE++FVWIPS+ AVVGGV V+G+ H+W+ADTQ +S ++ Sbjct: 149 QGKSFTVDGQQIEVEGLDGPSPEKTFVWIPSLKAVVGGVAVSGNIHLWVADTQTPESREN 208 Query: 214 WLGTLARIEKLKPRIVIPGHYAAGAPMTIASVKYTRDYIKAFDAETAKAVDSTALIAAMK 273 WL TL +I+ LKP IV+PGH+ AP T+ SV +T++Y+ +AE KA DS LIA MK Sbjct: 209 WLTTLEKIKALKPAIVVPGHFLDNAPQTLESVTFTQNYLTTLNAEIPKAKDSAELIAVMK 268 Query: 274 ARYPAPTNLSVLELSAKVAKGEIKW 298 YP + S LELSAKV K E+KW Sbjct: 269 KHYPELKDESSLELSAKVLKNEMKW 293 >VCA1049 [R] COG0491 Zn-dependent hydrolases, including glyoxylases Vch Vibrio cholerae Length = 292 Score = 231 bits (590), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 115/291 (39%), Positives = 178/291 (61%), Gaps = 9/291 (3%) Query: 8 ISRPLLALAAAVGILAAGAAAASDNVLKLDAYNPGDKALFPVSSVLVTGKQDAILVDAQF 67 ++R LL A + ++ AA L+L YNPG+ +FPVSS L++ ++ AILVDAQF Sbjct: 11 LTRTLLTSALLLPAFSSLAA------LELQTYNPGEHGIFPVSSTLISDEKQAILVDAQF 64 Query: 68 GRTQAEQVVEKIRASGKKLVAVYISHGDPDYYFGLDTIKAAYPDVKILATPQTVAHIKET 127 G ++V+ I+ SGK+L A+YIS GDPDYYFGL + A+P+V +LA+ V HI+ T Sbjct: 65 GVNDGAKLVDMIKQSGKELTAIYISAGDPDYYFGLQPLVEAFPNVPVLASESVVKHIEAT 124 Query: 128 VAQKLAFWGPKLGADAPTQTIVPDVLDGNTLTLEGKKLQVIGLDGPQPERSFVWIPSIGA 187 K+ +WGP L +AP + IVP V + L G K+++ L+ PQ +++W+P+ Sbjct: 125 KDAKIEYWGPILAENAPQKVIVPKVDNRTKFVLNGGKIEIKQLNHPQ---AYLWLPAEKT 181 Query: 188 VVGGVVVNGSEHIWMADTQGAQSHKDWLGTLARIEKLKPRIVIPGHYAAGAPMTIASVKY 247 ++GGV V H+W AD+Q Q+ +W+ TL R+ +LKP+ VIPGHY P ++ + Sbjct: 182 ILGGVAVMSDMHVWTADSQTKQARMEWVETLDRMLELKPKQVIPGHYGHEIPQGTQAISF 241 Query: 248 TRDYIKAFDAETAKAVDSTALIAAMKARYPAPTNLSVLELSAKVAKGEIKW 298 T++Y+ F+ + S+ +I M+A+YP + L+LSA+V GE W Sbjct: 242 TKEYLVKFEQALDSSTHSSQVIEKMRAQYPVLPDDGSLQLSAEVNMGEKSW 292 >VCA0900 [R] COG0491 Zn-dependent hydrolases, including glyoxylases Vch Vibrio cholerae Length = 304 Score = 207 bits (526), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 108/287 (37%), Positives = 165/287 (57%), Gaps = 3/287 (1%) Query: 12 LLALAAAVGILAAGAAAASDNVLKLDAYNPGDKALFPVSSVLVTGKQDAILVDAQFGRTQ 71 L L AA L+A A AA+ L LD YN D F V++ +V G+ +A++VD F + Sbjct: 21 LTKLLAATMTLSAQAMAATP--LTLDVYN-ADGNSFHVNATVVYGETEAMVVDTGFTKAD 77 Query: 72 AEQVVEKIRASGKKLVAVYISHGDPDYYFGLDTIKAAYPDVKILATPQTVAHIKETVAQK 131 A ++ K+ SGK L ++IS DPDYYFG + +K +P +++ATP A I++ + K Sbjct: 78 ALRIGAKVLDSGKTLKTIFISQADPDYYFGAEVLKQMFPQAEVIATPGVKAKIEQKLQGK 137 Query: 132 LAFWGPKLGADAPTQTIVPDVLDGNTLTLEGKKLQVIGLDGPQPERSFVWIPSIGAVVGG 191 L FW PK+GA+AP + ++P G TL ++G+ +++ G +G R ++WIP+ A++G Sbjct: 138 LDFWAPKMGANAPVKPVLPTAYQGKTLEIDGQTIEIRGTEGELKHRPYLWIPANAAILGN 197 Query: 192 VVVNGSEHIWMADTQGAQSHKDWLGTLARIEKLKPRIVIPGHYAAGAPMTIASVKYTRDY 251 V V G+ H+WMAD Q K W L + LKP++VIPGH G M +++ +++ Y Sbjct: 198 VAVYGNVHLWMADAQTDSERKAWAEQLDEMAALKPKVVIPGHMTPGTAMDSSAITFSQKY 257 Query: 252 IKAFDAETAKAVDSTALIAAMKARYPAPTNLSVLELSAKVAKGEIKW 298 + F A + +S LI M YP LE+ AKV GE+KW Sbjct: 258 LADFAKAKASSKNSAQLIEKMSKIYPDAGLPMALEIGAKVHTGEMKW 304