BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0216.p (219 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI1443 [R] COG1011 Predicted hydrolase (HAD superfamily) Bme B... 154 1e-37 mll7522 [R] COG1011 Predicted hydrolase (HAD superfamily) Mlo Me... 142 4e-34 SMc00081 [R] COG1011 Predicted hydrolase (HAD superfamily) Sme S... 139 3e-33 AGc1458 [R] COG1011 Predicted hydrolase (HAD superfamily) Atu Ag... 138 1e-32 CC3320 [R] COG1011 Predicted hydrolase (HAD superfamily) Ccr Cau... 129 5e-30 >BMEI1443 [R] COG1011 Predicted hydrolase (HAD superfamily) Bme Brucella melitensis Length = 205 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 84/207 (40%), Positives = 117/207 (56%), Gaps = 5/207 (2%) Query: 11 SSAGIRAVVFDFGGVLFDWNPLHLYQDLIPDAAEREHFLTHVCSPDWNIRQDGGRTLKEG 70 +S+ ++ VVFD G VL ++P + D+IPDA ER FL ++C+ WNI QD GR+ +E Sbjct: 2 NSSPVKHVVFDIGKVLIHYDPELAFLDIIPDAGERRWFLENICTSAWNIEQDRGRSWQEA 61 Query: 71 TELLLAEHPQHAPMIRAFYDRWTEMLRGPLHDGVELLRTLHDKDVPLFGLTNWSSETFPY 130 LLL HPQH IRAF W+ M+ D VE+LR L + LTN++S+TF Sbjct: 62 EALLLESHPQHHDHIRAFRRNWSRMVPHAYDDSVEILRGLIAAGHDVTMLTNFASDTFRE 121 Query: 131 ALANYDFLQIFRDIVVSGTEQCIKPDDVIYQIALTRYGKHLPNLKPSELVFLDDSAKNVE 190 A A + FL R + VSG + IKPD IY + +G L P+ +F+DD+ NVE Sbjct: 122 AQARFPFLTESRGVTVSGDIRLIKPDRAIYDHHVASFG-----LDPAATLFIDDTMHNVE 176 Query: 191 AARRLGWHAIHHVDCAETVKQLRELGL 217 A++ GW A+H A+ LR L Sbjct: 177 GAKQAGWQAVHFTSAAKLADDLRARQL 203 >mll7522 [R] COG1011 Predicted hydrolase (HAD superfamily) Mlo Mesorhizobium loti Length = 212 Score = 142 bits (359), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 80/203 (39%), Positives = 112/203 (55%), Gaps = 5/203 (2%) Query: 15 IRAVVFDFGGVLFDWNPLHLYQDLIPDAAEREHFLTHVCSPDWNIRQDGGRTLKEGTELL 74 IR +VFD G VL ++P + LIPDA ER+ F +VC+ DWNI QD GR+ +E LL Sbjct: 4 IRHIVFDIGRVLIHYDPNIPFSRLIPDAEERKWFFDNVCTHDWNIEQDRGRSWEEAEALL 63 Query: 75 LAEHPQHAPMIRAFYDRWTEMLRGPLHDGVELLRTLHDKDVPLFGLTNWSSETFPYALAN 134 +A+HP HA IR F W +M+ D V ++ L + + LTN++S+T A Sbjct: 64 IADHPDHAENIRNFRRHWHDMVPHAYDDSVAIMLGLIESGHDVTMLTNFASDTLAEARKR 123 Query: 135 YDFLQIFRDIVVSGTEQCIKPDDVIYQIALTRYGKHLPNLKPSELVFLDDSAKNVEAARR 194 +DFL R + +SG IKPD IY + +G L+PS +F+DDS KNV+ A+ Sbjct: 124 FDFLNRPRGVTISGEIGKIKPDRDIYDHHVAAFG-----LEPSATLFIDDSQKNVDGAKA 178 Query: 195 LGWHAIHHVDCAETVKQLRELGL 217 GW A+ D L LG+ Sbjct: 179 AGWQAVLFTDARTLQADLERLGI 201 >SMc00081 [R] COG1011 Predicted hydrolase (HAD superfamily) Sme Sinorhizobium meliloti Length = 218 Score = 139 bits (351), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 80/207 (38%), Positives = 109/207 (52%), Gaps = 5/207 (2%) Query: 11 SSAGIRAVVFDFGGVLFDWNPLHLYQDLIPDAAEREHFLTHVCSPDWNIRQDGGRTLKEG 70 SS IR +VFD G VL ++P Y L+PD AER F +VC+ DWNI QD GR+ +E Sbjct: 2 SSIDIRHIVFDIGKVLIHYDPNLPYSRLVPDEAERSWFFANVCTSDWNIEQDRGRSWEEA 61 Query: 71 TELLLAEHPQHAPMIRAFYDRWTEMLRGPLHDGVELLRTLHDKDVPLFGLTNWSSETFPY 130 +L+ HP+ IRAF W EM+ + V ++ L + LTN++S+TF Sbjct: 62 EAILIRNHPEREDHIRAFRRHWHEMVPHAYVETVAIMGGLIADGWDVTMLTNFASDTFRE 121 Query: 131 ALANYDFLQIFRDIVVSGTEQCIKPDDVIYQIALTRYGKHLPNLKPSELVFLDDSAKNVE 190 A Y FL + R + VSG + IKPD IY+ + +L P +F+DDSA NVE Sbjct: 122 AQKLYPFLTLPRGVTVSGDVRLIKPDLAIYRTHAEAF-----DLDPGATLFIDDSAANVE 176 Query: 191 AARRLGWHAIHHVDCAETVKQLRELGL 217 AR GWHA+ L G+ Sbjct: 177 GARAAGWHAVQFTGAERLKADLAAYGI 203 >AGc1458 [R] COG1011 Predicted hydrolase (HAD superfamily) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 203 Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 77/205 (37%), Positives = 110/205 (53%), Gaps = 5/205 (2%) Query: 15 IRAVVFDFGGVLFDWNPLHLYQDLIPDAAEREHFLTHVCSPDWNIRQDGGRTLKEGTELL 74 I +VFD G VL ++P Y LIPDA ER+ F +VC+ DWN+ QD GR ++ LL Sbjct: 4 IDHIVFDIGKVLIHYDPHIPYSRLIPDADERQWFFENVCTHDWNLEQDRGRRWEDAEALL 63 Query: 75 LAEHPQHAPMIRAFYDRWTEMLRGPLHDGVELLRTLHDKDVPLFGLTNWSSETFPYALAN 134 L P+ IRAF W EM+ D V ++ L D + LTN++S+TF A Sbjct: 64 LERFPEREEHIRAFRKFWHEMVSHSYDDSVAIMVALIDSGHDVTMLTNFASDTFREAQKM 123 Query: 135 YDFLQIFRDIVVSGTEQCIKPDDVIYQIALTRYGKHLPNLKPSELVFLDDSAKNVEAARR 194 + FL + R + VSG + +KPD IY + +G L P+ +F+DD+ NVE A+ Sbjct: 124 FPFLTLPRGVTVSGDVKLLKPDVAIYHLHAKEFG-----LNPATSLFIDDTLANVEGAKA 178 Query: 195 LGWHAIHHVDCAETVKQLRELGLPV 219 GW A+H + + LR G+ V Sbjct: 179 AGWQAVHFTGAEKLKQDLRAYGVEV 203 >CC3320 [R] COG1011 Predicted hydrolase (HAD superfamily) Ccr Caulobacter vibrioides Length = 205 Score = 129 bits (324), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 77/203 (37%), Positives = 112/203 (55%), Gaps = 6/203 (2%) Query: 16 RAVVFDFGGVLFDWNPLHLYQDLIPDAAEREHFLTHVCSPDWNIRQDGGRTLKEGTELLL 75 RAV++D G V+ W+P LY + + A+ + FL+HVC+ DW++ D G + + L+ Sbjct: 7 RAVLWDVGNVIVRWDPRALYAKIFKEPADLDRFLSHVCTLDWHVEHDRGVSFADNAAPLI 66 Query: 76 AEHPQHAPMIRAFYDRWTEMLRGPLHDGVELLRTLHDKDVPLFGLTNWSSETFPYALANY 135 A P+HA IRA+ +R+ EML GP+ + V ++ L ++ P F LTN +P A Sbjct: 67 ARFPEHAAEIRAWDERFDEMLSGPIPETVSVIEALAARETPQFALTNMPQSKWPIVQAKS 126 Query: 136 -DFLQIFRDIVVSGTEQCIKPDDVIYQIALTRYGKHLPNLKPSELVFLDDSAKNVEAARR 194 FRD VVSG E IKP IY+I L R G L +L+F+DDSA N+ AA Sbjct: 127 PAHFGHFRDAVVSGDEGVIKPHRRIYEIVLERTG-----LAADDLLFIDDSAANIAAAAE 181 Query: 195 LGWHAIHHVDCAETVKQLRELGL 217 +G+H H D A + + GL Sbjct: 182 MGFHTHHFTDPAALREAVASHGL 204