BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0142.p (248 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3532 [GEPR] COG0477 Permeases of the major facilitator superfa... 100 3e-21 ybjJ [GEPR] COG0477 Permeases of the major facilitator superfami... 95 1e-19 Z1072 [GEPR] COG0477 Permeases of the major facilitator superfam... 95 2e-19 ECs0925 [GEPR] COG0477 Permeases of the major facilitator superf... 95 2e-19 BMEI0267 [GEPR] COG0477 Permeases of the major facilitator super... 87 4e-17 >PA3532 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 383 Score = 100 bits (249), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 76/221 (34%), Positives = 116/221 (52%), Gaps = 4/221 (1%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 M GL+ + RIP++++ QLD L LL G+GA+ +FPL+ +L G+R Sbjct: 19 MAGLVIGNLMGRIPALKEQTQLDERALGQALLGVGVGALTAFPLSGFLVQRIGSRSVVIG 78 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 L++LL P LG++ L L + G + + DVA+N E+ G+ MS+LH Sbjct: 79 GCLIMLLVFPLLGLSQGWWQLALAFYVLGVSFAGMDVAMNIQAVDVERLLGKPCMSMLHG 138 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSADKK--I 178 + +G GAL SA A + PFWHFL L L LL L +A+ P + +K Sbjct: 139 MYSLGCLVGAL--SAAALAGLTPFWHFLILTALGLLSLPFFVRALLPPDPSKAGARKGGG 196 Query: 179 FAIPHGHLVALGLIGFCGAIVEGSIADWSGLYMKDHMNAGD 219 F +P L+ LGL+ C + EG +ADWS L++ ++A + Sbjct: 197 FTLPPRALLGLGLLILCAFVSEGGVADWSALFLHSVLDASE 237 >ybjJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 402 Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 112/220 (50%), Gaps = 9/220 (4%) Query: 3 GLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWYAG 62 GLL ASWA R P+IRD L + A + VL IG++ +AWL +G R Sbjct: 25 GLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTM 84 Query: 63 LVLLLTLPALGIAPNLALLMLFSA---IYGAASSCFDVAINALGAVAEKQAGRSIMSLLH 119 L+ + L +A L +LF+ ++GA+ +VAIN GA E++ ++++ ++H Sbjct: 85 SCALIGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMH 144 Query: 120 AWFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSAD---- 175 ++ +GT +GA +G A+ A V H L A++ + P+ + +A+P+ + +AD Sbjct: 145 GFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQH 204 Query: 176 --KKIFAIPHGHLVALGLIGFCGAIVEGSIADWSGLYMKD 213 K + L+ +G++ A EGS DW L M D Sbjct: 205 GEKGVPFYRDIQLLLIGVVVLAMAFAEGSANDWLPLLMVD 244 >Z1072 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 402 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 112/220 (50%), Gaps = 9/220 (4%) Query: 3 GLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWYAG 62 GLL ASWA R P+IRD L + A + VL IG++ +AWL +G R Sbjct: 25 GLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTM 84 Query: 63 LVLLLTLPALGIAPNLALLMLFSA---IYGAASSCFDVAINALGAVAEKQAGRSIMSLLH 119 L+ + L +A L +LF+ ++GA+ +VAIN GA E++ ++++ ++H Sbjct: 85 SCALVGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMH 144 Query: 120 AWFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSAD---- 175 ++ +GT +GA +G A+ A V H L A++ + P+ + +A+P+ + +AD Sbjct: 145 GFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQH 204 Query: 176 --KKIFAIPHGHLVALGLIGFCGAIVEGSIADWSGLYMKD 213 K + L+ +G++ A EGS DW L M D Sbjct: 205 GEKGVPFYRDIQLLLIGVVVLAMAFAEGSANDWLPLLMVD 244 >ECs0925 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 402 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 112/220 (50%), Gaps = 9/220 (4%) Query: 3 GLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWYAG 62 GLL ASWA R P+IRD L + A + VL IG++ +AWL +G R Sbjct: 25 GLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTM 84 Query: 63 LVLLLTLPALGIAPNLALLMLFSA---IYGAASSCFDVAINALGAVAEKQAGRSIMSLLH 119 L+ + L +A L +LF+ ++GA+ +VAIN GA E++ ++++ ++H Sbjct: 85 SCALVGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMH 144 Query: 120 AWFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPEPSAD---- 175 ++ +GT +GA +G A+ A V H L A++ + P+ + +A+P+ + +AD Sbjct: 145 GFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQH 204 Query: 176 --KKIFAIPHGHLVALGLIGFCGAIVEGSIADWSGLYMKD 213 K + L+ +G++ A EGS DW L M D Sbjct: 205 GEKGVPFYRDIQLLLIGVVVLAMAFAEGSANDWLPLLMVD 244 >BMEI0267 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 397 Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 10/223 (4%) Query: 1 MLGLLYASWAARIPSIRDNLQLDAATLSMVLLCGGIGAVGSFPLAAWLNAHYGARRTTWY 60 M G ++ WA +IP + L LD+A + +++L G+G++ P+A L+AH G+ Sbjct: 31 MNGYIFGGWAPKIPEFAERLGLDSAGMGLMILVCGLGSLAMMPVAGALSAHRGSGIVVRI 90 Query: 61 AGLVLLLTLPALGIAPNLALLMLFSAIYGAASSCFDVAINALGAVAEKQAGRSIMSLLHA 120 L + L + + PN+ ++ +G + DV++NA EK+ R+IMS HA Sbjct: 91 FALAFIPALLIITLVPNVVTAVIVMLYFGGTMAAMDVSMNANAVAVEKKMRRAIMSSCHA 150 Query: 121 WFCVGTFSGALLGSAVAALEVAPFWHFLALAVLFLLPLRLGYKAMPNDRPE-----PSAD 175 ++ + G L+G+A +A F + V + L A P+ P+ P + Sbjct: 151 FWSL----GGLIGAATGGFLIAQFGSIVHALVTMIAATILIIVAWPSIIPDTEHHHPDGE 206 Query: 176 KKIFAIPHGHLVAL-GLIGFCGAIVEGSIADWSGLYMKDHMNA 217 K+ A+P L L G++ + EG+I DW +M+ + A Sbjct: 207 KQKLALPRNPLPWLVGVMALFSMVPEGAILDWGAYHMRQDLGA 249