BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0134.p (355 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4447 [E] COG0079 Histidinol-phosphate/aromatic aminotransferas... 467 e-131 SMc03885 [E] COG0079 Histidinol-phosphate/aromatic aminotransfer... 415 e-116 CAC3031 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 375 e-104 L0065 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase... 315 1e-85 alr2092 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 234 2e-61 >PA4447 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Pae Pseudomonas aeruginosa Length = 351 Score = 467 bits (1202), Expect = e-131, Method: Compositional matrix adjust. Identities = 234/350 (66%), Positives = 272/350 (77%), Gaps = 3/350 (0%) Query: 1 MSKFWSPIVSRLTPYTPGEQPKISKLVKLNTNENPYGPSPKAIAAMVQEIGDSLRLYPNP 60 MSKFWSP V L PY PGEQPK+S+LVKLNTNENPYGPSP+A+AAM E+ D LRLYP+P Sbjct: 1 MSKFWSPFVKDLVPYVPGEQPKLSRLVKLNTNENPYGPSPQALAAMQAELNDDLRLYPDP 60 Query: 61 DAEPLKLAIAKRHGLSPAQVFVGNGSDEVLAHAFQALLKHGAPILFPDITYSFYPTYASL 120 + E LK A+A +G+ QVFVGNGSDEVLAH F L +H P+LFPD+TYSFYP Y L Sbjct: 61 NGERLKQAVAAHYGVQANQVFVGNGSDEVLAHIFHGLFQHDLPLLFPDVTYSFYPVYCGL 120 Query: 121 YEVEYRAVPLAGDFTIRVDDYLGQGEAIGGIIFPNPNAPTGCLLALDEVERLLAGNPDRV 180 Y + + + L F IRV+DY GGIIFPNPNAPTGCLL LD +E +L +PD V Sbjct: 121 YGIAHEKIALDERFRIRVEDY---ARPNGGIIFPNPNAPTGCLLPLDAIEAMLKASPDSV 177 Query: 181 VIVDEAYIDFGGDSAIDLVARHANLLVVQTLSKSRSLAGLRVGFAVGHADLISALERVKN 240 V+VDEAY+DFGG+SAI LV R+ NLLV QTLSKSRSLAGLRVG AVGHADL+ ALER+KN Sbjct: 178 VVVDEAYVDFGGESAIALVDRYPNLLVTQTLSKSRSLAGLRVGLAVGHADLVEALERIKN 237 Query: 241 SFNSYPLDRVAIAGATAAMEDDAHFDSTRNAVIASRDKLVGQLTALGFEVLPSAANFVFA 300 SFNSYPLDR+AIAGA AA EDDA+F T AVI SR+ L L ALGFEVLPSAANFVFA Sbjct: 238 SFNSYPLDRLAIAGAAAAFEDDAYFRRTCQAVIDSREALSASLQALGFEVLPSAANFVFA 297 Query: 301 RHPQHDAAGLAAKLRGDGIIVRHFTSTRINQFLRITVGTDESCGALIDSL 350 RHP+HDA +A+ LR G+IVRHF RI+QFLRIT+G+ E AL+D+L Sbjct: 298 RHPRHDAGQIASTLREQGVIVRHFKQARIDQFLRITIGSPEQNQALLDAL 347 >SMc03885 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Sme Sinorhizobium meliloti Length = 351 Score = 415 bits (1067), Expect = e-116, Method: Compositional matrix adjust. Identities = 219/354 (61%), Positives = 259/354 (73%), Gaps = 3/354 (0%) Query: 1 MSKFWSPIVSRLTPYTPGEQPKISKLVKLNTNENPYGPSPKAIAAMVQEIGDSLRLYPNP 60 MSK WSPIV+ L PY PGEQP+++ LVKLNTNE+PYGPS KA+ A+ LRLYP+P Sbjct: 1 MSKLWSPIVAALKPYVPGEQPRMADLVKLNTNESPYGPSEKALGAIRAAADTDLRLYPDP 60 Query: 61 DAEPLKLAIAKRHGLSPAQVFVGNGSDEVLAHAFQALLKHGAPILFPDITYSFYPTYASL 120 A L+ AIA RH +S +VFVGNGSDEVLAH F ALLKH P+LFPDI+YSFY TYA L Sbjct: 61 VALGLRQAIAARHQVSVGEVFVGNGSDEVLAHTFAALLKHDRPLLFPDISYSFYTTYAGL 120 Query: 121 YEVEYRAVPLAGDFTIRVDDYLGQGEAIGGIIFPNPNAPTGCLLALDEVERLLAGNPDRV 180 + +E VPL F I + DY G +I PNPNAPTG L L E+ERL+A +P + Sbjct: 121 FGIEAVEVPLDAAFRIDIADYRRPS---GAVILPNPNAPTGIGLPLAEIERLVADHPGQP 177 Query: 181 VIVDEAYIDFGGDSAIDLVARHANLLVVQTLSKSRSLAGLRVGFAVGHADLISALERVKN 240 V++DEAYIDFGG+SAI LV ++ NLLVVQT SKSR+LAGLRVGFA+G LI ALERVK+ Sbjct: 178 VVIDEAYIDFGGESAIALVPKYDNLLVVQTFSKSRALAGLRVGFAIGQRPLIEALERVKD 237 Query: 241 SFNSYPLDRVAIAGATAAMEDDAHFDSTRNAVIASRDKLVGQLTALGFEVLPSAANFVFA 300 SFNSYPL R A AGATAA+ED+A F++TR +IASR KL +L GFEVLPS ANFVFA Sbjct: 238 SFNSYPLGRAAQAGATAAIEDEAWFEATRGKIIASRAKLTSELEKRGFEVLPSQANFVFA 297 Query: 301 RHPQHDAAGLAAKLRGDGIIVRHFTSTRINQFLRITVGTDESCGALIDSLRKHL 354 RHP H LAAKLR +IVRHF RI FLRIT+GTD C L+ +L + L Sbjct: 298 RHPGHAGQTLAAKLRERAVIVRHFAKPRIADFLRITIGTDAECAKLVAALDEVL 351 >CAC3031 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Cac Clostridium acetobutylicum Length = 352 Score = 375 bits (963), Expect = e-104, Method: Compositional matrix adjust. Identities = 174/355 (49%), Positives = 242/355 (68%), Gaps = 3/355 (0%) Query: 1 MSKFWSPIVSRLTPYTPGEQPKISKLVKLNTNENPYGPSPKAIAAMVQEIGDSLRLYPNP 60 MSKFW+ V +L PY PGEQPK K +KLNTNENPY PSP I A+ +E L+LYP+P Sbjct: 1 MSKFWNERVKKLEPYVPGEQPKDQKYIKLNTNENPYPPSPMVIEAIKKEADYKLKLYPDP 60 Query: 61 DAEPLKLAIAKRHGLSPAQVFVGNGSDEVLAHAFQALLKHGAPILFPDITYSFYPTYASL 120 + + LK IA+ +G+S +VFVGNGSDEVLA +F + F DITYSFY YA+L Sbjct: 61 NCDSLKRTIAEYYGISDKEVFVGNGSDEVLAFSFMTFFSPRKTVFFADITYSFYKVYANL 120 Query: 121 YEVEYRAVPLAGDFTIRVDDYLGQGEAIGGIIFPNPNAPTGCLLALDEVERLLAGNPDRV 180 + +PL DF++ +D++ GG+I PNPNAPT + L +++++L N D V Sbjct: 121 LNLNCELIPLKEDFSLDLDNFC---RCNGGVIIPNPNAPTAKYIGLSDIKKILDWNKDSV 177 Query: 181 VIVDEAYIDFGGDSAIDLVARHANLLVVQTLSKSRSLAGLRVGFAVGHADLISALERVKN 240 VI+DEAYIDFGG+SA+ + + NLL+VQTLSKSRSLAGLR+GFA+G +LI L RVKN Sbjct: 178 VIIDEAYIDFGGESAVKFIKDYKNLLIVQTLSKSRSLAGLRIGFAMGSPELIEGLSRVKN 237 Query: 241 SFNSYPLDRVAIAGATAAMEDDAHFDSTRNAVIASRDKLVGQLTALGFEVLPSAANFVFA 300 S NSY LDR+AI GA AA +D +F+ R +IA+R+++ +L +GF+V+ S ANF+F Sbjct: 238 SINSYTLDRLAIVGAEAAFKDKEYFEDARRKIIATRERVSTELKQIGFKVIESKANFIFI 297 Query: 301 RHPQHDAAGLAAKLRGDGIIVRHFTSTRINQFLRITVGTDESCGALIDSLRKHLA 355 H A + +LR GI+VR+F + RI+ FLR+++GTD+ +D +++ +A Sbjct: 298 SHTTISAESIFNELRKRGILVRYFKTARIDNFLRVSIGTDKEMSEFMDKIKECIA 352 >L0065 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Lla Lactococcus lactis Length = 360 Score = 315 bits (806), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 155/352 (44%), Positives = 224/352 (63%), Gaps = 7/352 (1%) Query: 5 WSPIVSRLTPYTPGEQPKISKLVKLNTNENPYGPSPKAIAAMVQE--IGDSLRLYPNPDA 62 W + ++PY GEQP+++ ++KLNTNENPY P+ ++A + E +LRLYP+ DA Sbjct: 3 WQNNLRSVSPYIAGEQPELTDIIKLNTNENPYPPT--SVAQLFNERYKTKNLRLYPSTDA 60 Query: 63 EPLKLAIAKRHGLSPAQVFVGNGSDEVLAHAFQALLKHGAPILFPDITYSFYPTYASLYE 122 + L+ +A H L QV +GNGSDEVL+ +F +P+L PDITYSFYP Y LY Sbjct: 61 KSLRKKLADYHHLEVEQVIIGNGSDEVLSLSFLTFFNSQSPLLMPDITYSFYPIYCELYR 120 Query: 123 VEYRAVPLAGDFTIRVDDYLGQGEAIGGIIFPNPNAPTGCLLALDEVERLLAGNPDRVVI 182 + ++ VP+ DF + + DY + GGI+ NP+APT L L ++E +L N + +V+ Sbjct: 121 IPFQKVPVDDDFKVLIKDYCIEN---GGIVIANPDAPTALALNLKDIEEILKKNQNSIVL 177 Query: 183 VDEAYIDFGGDSAIDLVARHANLLVVQTLSKSRSLAGLRVGFAVGHADLISALERVKNSF 242 ++EAYIDFGG++ + L+ ++ NL+VVQT SKSRSLAG+R+G A G A+ IS L VKNSF Sbjct: 178 INEAYIDFGGETCLPLLKKYDNLVVVQTFSKSRSLAGIRLGVAYGSAEAISHLYDVKNSF 237 Query: 243 NSYPLDRVAIAGATAAMEDDAHFDSTRNAVIASRDKLVGQLTALGFEVLPSAANFVFARH 302 NSYP+D +A A++ D+ +F +I +R+ L LGFEV S ANFVF H Sbjct: 238 NSYPIDSLAQIIGEASLMDEHYFQKNIQKIIKTREVFKDNLVNLGFEVTDSKANFVFVHH 297 Query: 303 PQHDAAGLAAKLRGDGIIVRHFTSTRINQFLRITVGTDESCGALIDSLRKHL 354 P+ A L L IIVRH+ RI+ +LRIT+GT++ +I+ L+ +L Sbjct: 298 PKVKAEELFKALYEAKIIVRHWNQPRIDDWLRITIGTNKEMNKVIEFLKGYL 349 >alr2092 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Nos Nostoc sp. PCC 7120 Length = 353 Score = 234 bits (598), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 137/356 (38%), Positives = 212/356 (59%), Gaps = 9/356 (2%) Query: 1 MSKFWSPIVSRLTPYTPGEQP-KISKLVKLNTNENPYGPSPKAIAAMVQEIGDSLRLYPN 59 M+ ++ V + Y PGEQP + ++++KLN+NENPY PSP+A+AA+ G+ LR YP Sbjct: 1 MTNYFRSNVEAMASYVPGEQPPQGTQVIKLNSNENPYPPSPEALAAIKDIDGECLRRYPE 60 Query: 60 PDAEPLKLAIAKRHGLSPAQVFVGNGSDEVLAHAFQALLKHGAPILFPDITYSFYPTYAS 119 P E + A+++ G+ V VGNGSDE+L+ +A + +++P TY Y T Sbjct: 61 PFGEEFRKAVSQLLGVPCNWVIVGNGSDEILSIVIRACAEPTRKVVYPVPTYVLYRTLTE 120 Query: 120 LYEVEYRAVPLAGDFTIRVDDYLGQGEAIGGIIF-PNPNAPTGCLLALDEVERLLAGNPD 178 + + +P + V D + A G + F +PN+P+G ++ D++ R LA Sbjct: 121 MQAADILEIPYREYNILPVADLIA---AHGSVTFIASPNSPSGHVVPSDDL-RKLASELS 176 Query: 179 RVVIVDEAYIDFGGDSAIDLVARHANLLVVQTLSKSRSLAGLRVGFAVGHADLISALERV 238 V+++DEAY+DF +SA++LV H N+++++TLSK SLAGLR+GF VG+ L++ L +V Sbjct: 177 GVLVIDEAYVDFAEESALNLVQDHENVILIRTLSKGYSLAGLRLGFGVGNPQLLNGLFKV 236 Query: 239 KNSFNSYPLDRVAIAGATAAMEDDAHFDSTRNAVIASRDKLVGQLTALGFEVLPSAANFV 298 K+S+N +D +A ATAA+ D A+ ++ V ASR +L L LGF V S ANF+ Sbjct: 237 KDSYN---VDAIACKVATAAITDQAYKNACVAKVKASRTRLAKDLKQLGFCVWDSQANFL 293 Query: 299 FARHPQHDAAGLAAKLRGDGIIVRHFTSTRINQFLRITVGTDESCGALIDSLRKHL 354 + PQ +A L +LR I++R+F + LRITVGTDE L+ +LR L Sbjct: 294 LTQPPQGNAEYLYQQLREKKILIRYFKQPGLEDKLRITVGTDEQNQILLQALRDLL 349