BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0082.p (478 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3191 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 323 5e-88 CC1181 [T] COG0642 Signal transduction histidine kinase Ccr Caul... 192 1e-48 BMEII0792 [T] COG0642 Signal transduction histidine kinase Bme B... 189 1e-47 SMb20218 [T] COG0642 Signal transduction histidine kinase Sme Si... 186 9e-47 SMc01595 [T] COG0642 Signal transduction histidine kinase Sme Si... 176 1e-43 >PA3191 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 473 Score = 323 bits (829), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 188/453 (41%), Positives = 260/453 (57%), Gaps = 12/453 (2%) Query: 26 LIWAAQLRTKSEAETRVAAQHLAHSASGAIRYFMTLPANYRPIMIQQLREMGGTRFFINA 85 L W + LR+ +++ LA+S + ++ YF +LP YRP+++ QLR MGGTRFF++ Sbjct: 26 LFWLSHLRSSQREGLLTSSRSLAYSMAASVSYFRSLPLGYRPLVLDQLRSMGGTRFFVSL 85 Query: 86 NSALVPIP--PIAPNSLADIATEAAAETLKSDLAFLPEFHLSFAWPDNLPVSDDGLKIGD 143 N + + P PN A E + L L E + F PD L + + LK+ + Sbjct: 86 NDRPLEMRALPDTPNKQA--VLEIVQDVLHQRLGKEVELQVEFVSPDELRLFNGALKLDE 143 Query: 144 LPDSWVQHILLIKPNPAPVLVIQTQIESGKWLYLAALMPNPYFLDSSNPLSLDRVVLQGL 203 LP SW + L ++P PVLV Q +I +WLY+A+LMP PY L +V+ Sbjct: 144 LPRSWAHYALTLEPVNPPVLVTQIRIGESEWLYIASLMPAPYVSLEPEGLQPQQVLSIVF 203 Query: 204 SLAAILLLTILVVRWTTRPLAALSDAAEAFGKGETVPELPETGSREFVKTARAFSGMRER 263 + +LL T L++ W +RPL L+ AA G L E G+ E V+ ARAF+ M ER Sbjct: 204 TSLLLLLFTGLLMHWQSRPLKRLARAARDLALGSPSAALEERGASELVEVARAFNTMHER 263 Query: 264 IKRYLEDRERLFVSISHDLRTPITRLKLRTELLDDDDLRTEFHDDLDELDMMVKGALQSV 323 I RYL +R +LF +ISHDLRTPITRL+LR ELL+D+ L+ +F DLDEL+++VKGALQ V Sbjct: 264 IDRYLNERGQLFSAISHDLRTPITRLRLRVELLEDERLQEKFGRDLDELELLVKGALQCV 323 Query: 324 KDSDIHENRTEVRLDALVARMIRDASMAGHEVAFEPSGVNVMAKPLALKRAIGNLFDNAL 383 KD+DIHEN V L+ L+ + G + KPLALKR IGNL DNAL Sbjct: 324 KDTDIHENVESVDLNLLLQHIAEPYLADGRVEVVGRAAEPYPGKPLALKRCIGNLLDNAL 383 Query: 384 HYGEKVEIAIRQSQALEGDMVEIEIRDHGPGVPEDAMGSLFQPYVRLEHGRSANSGGMGL 443 YGE+ +++ + V + + D GPGVPE + +F+P RL S G GL Sbjct: 384 KYGERARLSLEDGP----EAVVLHVDDDGPGVPEQRLEQIFEPRFRL----SPRGQGYGL 435 Query: 444 GLGIARNIVQAHGGELLLRNHPNGGLIATIIVP 476 GLGIARNI HGGE+ L+N GGL ++ +P Sbjct: 436 GLGIARNIAHTHGGEVSLQNRREGGLRVSLRLP 468 >CC1181 [T] COG0642 Signal transduction histidine kinase Ccr Caulobacter vibrioides Length = 475 Score = 192 bits (489), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 110/275 (40%), Positives = 165/275 (60%), Gaps = 6/275 (2%) Query: 204 SLAAILLLTILVVRWTTRPLAALSDAAEAFGKGETVPELPETGSREFVKTARAFSGMRER 263 S+ A+ L L R +P+ A +DAAE GK P L TGS E V A AF+ M+ER Sbjct: 206 SVIAVTPLAWLFARRLAQPITAFADAAERLGKDPRTPPLNMTGSGEVVAAASAFNMMQER 265 Query: 264 IKRYLEDRERLFVSISHDLRTPITRLKLRTELLDDDDLRTEFHDDLDELDMMVKGALQSV 323 ++RY+EDR + +I+HDLRTP+TRLK R E +D+R + D+D+++ M+ L V Sbjct: 266 LRRYVEDRTAMVGAIAHDLRTPLTRLKFRIEAA-PEDIRPKLAADIDQMEAMISATLGFV 324 Query: 324 KDSDIHENRTEVRLDALVARMIRDASMAGHEVAFEPSGVNVM-AKPLALKRAIGNLFDNA 382 +D++ RT++ L +L+ ++ +A+ G + E S V+ P+ALKR + NL +NA Sbjct: 325 RDTNRPAERTKLELSSLLESVMDEAAETGGDATVERSEKTVIEGDPVALKRLVSNLVENA 384 Query: 383 LHYGEKVEIAIRQSQALEGDMVEIEIRDHGPGVPEDAMGSLFQPYVRLEHGRSANSGGMG 442 L YG + R E M IEI D GPGVP + +F+P+ R E R+ +GG+G Sbjct: 385 LKYGGRA----RGRVFSEDGMAIIEIDDDGPGVPPAELERVFEPFYRGEPSRNRETGGIG 440 Query: 443 LGLGIARNIVQAHGGELLLRNHPNGGLIATIIVPA 477 LGL + R++ +AHGG+++L N GGL AT+ +PA Sbjct: 441 LGLAVVRSLARAHGGDVVLANRLGGGLRATVKLPA 475 >BMEII0792 [T] COG0642 Signal transduction histidine kinase Bme Brucella melitensis Length = 474 Score = 189 bits (481), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 115/327 (35%), Positives = 179/327 (54%), Gaps = 34/327 (10%) Query: 163 LVIQTQIESGKWL-YLAALMP-NPYFLDSSNPLSLDRVVLQGLSLAAILLLTILVVRWTT 220 L Q G+WL ++ + P +P + PL + L IL W T Sbjct: 162 LTTSLQFNDGRWLNFITHITPIDPIVTSDTIPL-----------FTLVALCVILGAIWAT 210 Query: 221 RPLAA----LSDAAEAFGKGETVPELPETGSREFVKTARAFSGMRERIKRYLEDRERLFV 276 + L A L DA + G P LPETG RE+ ARA + M+ R+ Y+ +RE+L Sbjct: 211 QRLIAPYRILEDAIDRIGGDLKSPPLPETGIREYTAAARAVNSMQARLLDYVAEREQLAA 270 Query: 277 SISHDLRTPITRLKLRTELLDDDDLRTEFHDDLDELDMMVKGALQSVKDSDIHENRTEVR 336 +++HDLRTP+TR+KLR ELLDDD LR DL++++ + + + HE + Sbjct: 271 ALAHDLRTPLTRMKLRMELLDDDALRQSLSRDLNDIEAISRSVIDFATSELAHEKAERLD 330 Query: 337 LDALVARMIRDASMAGH--EVAFEPSGVN-----VMAKPLALKRAIGNLFDNALHYGEKV 389 L +L+ S+A +V+ + G + + +P++++R I NL DNAL YG KV Sbjct: 331 LWSLL------LSVADKYPQVSLDEKGSDYRDAICLCQPISIQRCITNLIDNALAYGGKV 384 Query: 390 EIAIRQSQALEGDMVEIEIRDHGPGVPEDAMGSLFQPYVRLEHGRSANSGGMGLGLGIAR 449 +++ + +GD + + I+D+GPG+ + + +F+P+ R + R+ SGG GLGL IAR Sbjct: 385 RLSLHR----DGDDLLLRIKDNGPGISPERIEEMFKPFSRADKSRNRESGGFGLGLTIAR 440 Query: 450 NIVQAHGGELLLRNHPNGGLIATIIVP 476 NI + +GGE+ LRN P GGLIA + +P Sbjct: 441 NIARKNGGEISLRNDPAGGLIAELRLP 467 >SMb20218 [T] COG0642 Signal transduction histidine kinase Sme Sinorhizobium meliloti Length = 454 Score = 186 bits (472), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 106/271 (39%), Positives = 156/271 (57%), Gaps = 5/271 (1%) Query: 205 LAAILLLTILVVRWTTRPLAALSDAAEAFGKGETVPELPETGSREFVKTARAFSGMRERI 264 L+ ++L + VR TRPLA L+ AA+ P L ETG RE A AF+ MR+RI Sbjct: 170 LSLLVLCSWFAVRQATRPLADLAKAADTLDPNSRTPRLSETGPREVAYAATAFNAMRDRI 229 Query: 265 KRYLEDRERLFVSISHDLRTPITRLKLRTELLDDDDLRTEFHDDLDELDMMVKGALQSVK 324 +YLE+R ++ +ISHDL+TPITR+KLR E+ + R + DLDE++ +VK + + Sbjct: 230 AQYLEERVQILAAISHDLQTPITRMKLRAEMAEASIERDKLITDLDEVERLVKEGVAYAR 289 Query: 325 DS-DIHENRTEVRLDALVARMIRDASMAGHEVAFEPSGVN-VMAKPLALKRAIGNLFDNA 382 + E + + L + + + D G V G ++ +P AL+R + NL DNA Sbjct: 290 SAHGKDEKASRIDLASFIESLAYDYQDTGKAVTVAELGDGAIVTRPHALRRILTNLIDNA 349 Query: 383 LHYGEKVEIAIRQSQALEGDMVEIEIRDHGPGVPEDAMGSLFQPYVRLEHGRSANSGGMG 442 L +G EI +++ EG V I++ D GPG+PED + ++ QP+ RLE RS ++GG G Sbjct: 350 LKFGGSAEIEVQRRP--EG-TVTIKVLDRGPGIPEDQLEAVLQPFFRLEQSRSRDTGGTG 406 Query: 443 LGLGIARNIVQAHGGELLLRNHPNGGLIATI 473 LGL IA+ + GG L LRN GGL A + Sbjct: 407 LGLAIAQQLATVIGGSLTLRNRDGGGLAAEL 437 >SMc01595 [T] COG0642 Signal transduction histidine kinase Sme Sinorhizobium meliloti Length = 460 Score = 176 bits (446), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 101/274 (36%), Positives = 158/274 (57%), Gaps = 8/274 (2%) Query: 206 AAILLLTI--LVVRWTTRPLAALSDAAEAFGKGETVPELPETGSREFVKTARAFSGMRER 263 A+++LLTI L +R RP+ AL+ AAE+FGKG+ + + G+ E + AF MRER Sbjct: 191 ASLVLLTIAILFLRGQIRPILALASAAESFGKGQKIDDFAPRGANEIRRAGLAFILMRER 250 Query: 264 IKRYLEDRERLFVSISHDLRTPITRLKLRTELLDDDDLRTEFHDDLDELDMMVKGALQSV 323 I+R +E R + +SHDLRT +TR KL+ L+ ++ + D++++ M++G L Sbjct: 251 IERQIEQRTAMLTGVSHDLRTILTRFKLQLALVGNNPDLESLNQDVEDMQNMLEGYLAFA 310 Query: 324 KDSDIHENRTEVRLDALVARMIRDASMAGHEVAFEPSGVN-VMAKPLALKRAIGNLFDNA 382 + D E+ ++L L+AR+ +A + G + G N + +P A R + NL NA Sbjct: 311 R-GDAEEDVGRLKLSDLMARLAAEAELYGKTLTTAIQGENEIHVRPNAFTRLVSNLASNA 369 Query: 383 LHYGEKVEIAIRQSQALEGDMVEIEIRDHGPGVPEDAMGSLFQPYVRLEHGRSANSGGMG 442 Y V I RQS + I + D GPG+PE + +F+P+ RL+ R+ +S G G Sbjct: 370 YRYANTVHIEARQS----AKWLTITVDDDGPGIPERSREDVFKPFFRLDEARNLDSSGTG 425 Query: 443 LGLGIARNIVQAHGGELLLRNHPNGGLIATIIVP 476 LGL +AR+I ++HGG + L + P GGL AT+ VP Sbjct: 426 LGLAVARDIARSHGGNVTLADSPLGGLRATVRVP 459