BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0068.p (327 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2172 [GEPR] COG0477 Permeases of the major facilitator superf... 236 8e-62 PA3573 [GEPR] COG0477 Permeases of the major facilitator superfa... 196 9e-50 Cj0035c [GEPR] COG0477 Permeases of the major facilitator superf... 158 2e-38 YPO1267 [GEPR] COG0477 Permeases of the major facilitator superf... 149 1e-35 STM2221 [GEPR] COG0477 Permeases of the major facilitator superf... 147 2e-35 >RSc2172 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 407 Score = 236 bits (601), Expect = 8e-62, Method: Compositional matrix adjust. Identities = 123/264 (46%), Positives = 175/264 (66%), Gaps = 1/264 (0%) Query: 56 GAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETRD 115 GAA+A+S LMLV G+APILAP IGG +L ++WR IFA L FGV+ L H +M E+ D Sbjct: 141 GAAQAYSTLMLVMGVAPILAPMIGGAVLQVTSWRMIFAVLAAFGVLSLAAVHFLMRESLD 200 Query: 116 QAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQN 175 AH PL +GRVLR Y LLR R + AY CG + +G+FAYI+ PFVLI+ +G+ P + Sbjct: 201 AAHARPLAVGRVLRDYWELLRDRHYAAYTACGAVFVSGMFAYITASPFVLIDHYGLSPSH 260 Query: 176 FGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYESLPLL 235 + +VFG+NA G+IA S+IN RL+ + + RVL + +W+PA + A +V G+ LPL+ Sbjct: 261 YAWVFGSNAAGMIAASRINVRLMRRSTPARVLRRALWMPAATSVAAAAVVGAGFMPLPLV 320 Query: 236 LIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDGTA 295 L F +++ G + PN A+A+A QG +AGT +ALMG +QFG+GM++G ++ + G A Sbjct: 321 LAALFCYVASIGCISPNTGALAMAGQGARAGTGSALMGAMQFGLGMVTGTVVAAFGQGAA 380 Query: 296 LPLTTLMAVCGIAALLLYRYVARH 319 PL +MAV + AL L +H Sbjct: 381 -PLLGMMAVSAVLALWLGLRATQH 403 >PA3573 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 392 Score = 196 bits (497), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 121/270 (44%), Positives = 166/270 (61%), Gaps = 5/270 (1%) Query: 56 GAARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETRD 115 GAA+AFS LMLV GLAPILAP GGLLL + W++IF LT+F + + + ET Sbjct: 125 GAAKAFSQLMLVMGLAPILAPVAGGLLLDWQGWQSIFVCLTLFAALAGLGVALWLPETIP 184 Query: 116 QAHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQN 175 P L L QY L R F+AY L GG+ AG+FAYI+G P+V I+L+GI ++ Sbjct: 185 ADGERP-PLSGALGQYRRLFADRLFLAYGLSGGVAMAGMFAYIAGSPYVFIQLYGIPAEH 243 Query: 176 FGFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYESLPL- 234 +G++FG+NA G I +Q+NARL+ R L +IIW L +A+L + L Sbjct: 244 YGWLFGSNAAGFIVMAQVNARLLRYRGPAFWLRRIIW--GYLACGLALLGIASLQPATLW 301 Query: 235 -LLIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDG 293 LL+ FG ++ G + PNASA A+A QG+ AG+A+ALMG+LQF + + ++GV HDG Sbjct: 302 PLLVPLFGCVASLGCIIPNASACAMAGQGQHAGSASALMGSLQFSVAAGASALVGVLHDG 361 Query: 294 TALPLTTLMAVCGIAALLLYRYVARHTMQA 323 TA+P+T ++AVCG A LL R QA Sbjct: 362 TAIPMTLVIAVCGAVATLLAWQTGRLERQA 391 >Cj0035c [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 400 Score = 158 bits (399), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 148/257 (57%), Gaps = 1/257 (0%) Query: 57 AARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETRDQ 116 AA F+++M+ LAP+L+P GG+LL + +W +IFATL G++ + ++E+ Sbjct: 136 AAGIFALMMVFSSLAPMLSPTFGGILLEYFSWHSIFATLFALGILLFLMILFGLKESAPH 195 Query: 117 AHVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQNF 176 ++ Y +L ++F+ Y+LC A +FAYI+G FV + + Q F Sbjct: 196 LKNKKFSHHEAMKSYKFVLSDKRFLVYILCASFALAAMFAYITGSSFVFTQFFSLSEQKF 255 Query: 177 GFVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTTIVAVLVACGYESLPLLL 236 +FGANA+G + C+ INARLV+K ++++L K + I ++T++ ++ A + + L Sbjct: 256 ALLFGANALGFVICANINARLVLKYESEKILAKALMI-MFISTVILLVNAFFHPNFLLFE 314 Query: 237 IGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDGTAL 296 + F ++ GF+ PN + +A+A+ + +GTA+A++GT+QFG L ++G + T + Sbjct: 315 LSIFTSIAMLGFIAPNTTTLAMARFKEHSGTASAVLGTVQFGFAGLISFVVGAINANTPI 374 Query: 297 PLTTLMAVCGIAALLLY 313 L +M C + A ++Y Sbjct: 375 ILAFVMCACVLVANMIY 391 >YPO1267 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 149 bits (375), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 89/263 (33%), Positives = 147/263 (55%), Gaps = 5/263 (1%) Query: 58 ARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETRDQA 117 +R S ++LV +AP+LAP IGG LL + +W AIF T+ ++ + ++ET Sbjct: 133 SRMMSFVVLVMTIAPLLAPIIGGALLVWFSWHAIFWTMAGAALVGAVLVALFIQETLPPE 192 Query: 118 HVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQNFG 177 HL + + L RH++ ++Y+L G AG+F+++S GPFV I+L+G+ PQNFG Sbjct: 193 RRQKFHLRTTIGNFGSLFRHKRVLSYMLASGFSFAGMFSFLSAGPFVYIDLNGVSPQNFG 252 Query: 178 FVFGANAIGLIACSQINARLVIKRSADRV--LGKIIWIPAILTTIVAVLVACGYESLPLL 235 + F N + L + IN+R V + A ++ G I+ + +V + G+ + L Sbjct: 253 YYFALNIVFLFLMTFINSRNVRRFGALKMFRFGLIVQFVMGIWLVVVCVAGLGFWA---L 309 Query: 236 LIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDGTA 295 ++G ++ C + NA A+ L AGTA++L GTL+FGIG + G ++ + +A Sbjct: 310 VLGVAAYVGCIAMITSNAMAVILDDFPHMAGTASSLAGTLRFGIGAVVGTLLSMASSRSA 369 Query: 296 LPLTTLMAVCGIAALLLYRYVAR 318 P+ + MA C I A+LLY Y +R Sbjct: 370 WPMVSSMAFCIIVAMLLYLYASR 392 >STM2221 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 396 Score = 147 bits (372), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 81/263 (30%), Positives = 145/263 (55%), Gaps = 5/263 (1%) Query: 58 ARAFSMLMLVFGLAPILAPFIGGLLLTFSTWRAIFATLTVFGVICLIFTHRVMEETRDQA 117 +R S +MLV +AP++AP +GG +L + +W IF L + ++ + +++ET Sbjct: 133 SRMMSFVMLVTTIAPLMAPIVGGWVLVWLSWHYIFWILAIAAILASVMIFALIKETLPVE 192 Query: 118 HVVPLHLGRVLRQYLGLLRHRQFMAYVLCGGLIQAGLFAYISGGPFVLIELHGIKPQNFG 177 P H+ + + L RH++ ++Y+L G AG+F+++S GPFV IE++ + PQ+FG Sbjct: 193 RRQPFHIRTTIGNFAALFRHKRVLSYMLASGFSFAGMFSFLSAGPFVYIEINHVPPQDFG 252 Query: 178 FVFGANAIGLIACSQINARLVIKRSADRVLGKIIWIPAILTT--IVAVLVACGYESLPLL 235 + F N + L + IN+R V + A + +WI + + + L+ G+ + L Sbjct: 253 YYFALNIVFLFVMTIINSRFVRRVGALNMFRAGLWIQFAMAVWMVFSALMGIGFWA---L 309 Query: 236 LIGFFGFLSCHGFVGPNASAIALAQQGKQAGTAAALMGTLQFGIGMLSGVIMGVWHDGTA 295 ++G F+ C V NA A+ L + AGTA++L GT +FGIG + G ++ + +A Sbjct: 310 VVGVAAFVGCVSMVSSNAMAVILDEFPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSA 369 Query: 296 LPLTTLMAVCGIAALLLYRYVAR 318 P+ +A+C ++L Y Y +R Sbjct: 370 WPMIWSIALCAACSILFYLYASR 392