BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0062.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 609 e-174 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 593 e-169 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 578 e-165 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 548 e-156 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 282 1e-75 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 609 bits (1570), Expect = e-174, Method: Compositional matrix adjust. Identities = 294/412 (71%), Positives = 348/412 (84%) Query: 8 SSSKFATVLRVTSGNFMEMFDFFLFGFYASYISKAFFPSGDEFASLMLTFMTFGAGFLMR 67 + SK ++ RV SGNF+EM+DF ++G+YA I+ FFP+ +EF SLML+ +TFG GFLMR Sbjct: 7 NESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMR 66 Query: 68 PLGAIILGAYVDRVGRRQGLIVTLALMALGTVLIAFVPGYATIGLLAPALVLIGRLLQGF 127 PLGA+ILGAY+DR GRR GLI+TL LMA GT+LIA VPGYATIGL AP LVLIGRLLQGF Sbjct: 67 PLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGF 126 Query: 128 SAGVELGGVSVYLAEMATPGRKGFYVSWQSASQQVAIIFAAAIGYGLNIWLTKDQVGDWG 187 SAGVELGGVSVYLAE++TPGRKGF+VSWQSASQQVA++FAA +G L+ L+ ++G+WG Sbjct: 127 SAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWG 186 Query: 188 WRVPFFIGCMIVPVLFVIRRSLQETEEFLARKRKPNLNEIFRSMVENWKLVIAGMMLVSM 247 WRVPF +GC+IVP LF+IRRSLQETEEF RK +P L EIFRSM ENW+LV AG +LV M Sbjct: 187 WRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAGTLLVVM 246 Query: 248 TTVSFYLITVYTPTFGKNVLKLSTESALIVTFCVGISNFIWLPVMGALSDRIGRRPLLLV 307 TTVSFYLIT YTPTFGK+VL LS +LIVT CVG SNF WLPVMG++SDRIGRRPLL+ Sbjct: 247 TTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLIT 306 Query: 308 FTILTILTAYPAMTWLVGDATFGKMLVVELWLSFLYASYNGAMVVALTEVMPVDVRTAGF 367 FT LT+LTAYPAM WL+ + +FG++L VELWLSFLY SYNGAMVV LTE+MP VRT GF Sbjct: 307 FTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTGF 366 Query: 368 SLAYSLATAVFGGFTPAIATGLIEITHDKAAPGLWMSFAAVCGLIATLVLYR 419 SLAYSLATA+FGGFTPAIAT LI T +KA PGLW+SFAA+CGL+ATL++ + Sbjct: 367 SLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVK 418 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 593 bits (1530), Expect = e-169, Method: Compositional matrix adjust. Identities = 286/414 (69%), Positives = 341/414 (82%) Query: 8 SSSKFATVLRVTSGNFMEMFDFFLFGFYASYISKAFFPSGDEFASLMLTFMTFGAGFLMR 67 + SK + RV SGNF+EMFDF ++G+YA+ I+ FFP+G+ F SLML+ MTFGAGFLMR Sbjct: 7 NESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMR 66 Query: 68 PLGAIILGAYVDRVGRRQGLIVTLALMALGTVLIAFVPGYATIGLLAPALVLIGRLLQGF 127 PLGAI+LGAY+DR GRR GLI+TL LMA GT+LIA VPGY TIGL AP LVLIGRLLQGF Sbjct: 67 PLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGF 126 Query: 128 SAGVELGGVSVYLAEMATPGRKGFYVSWQSASQQVAIIFAAAIGYGLNIWLTKDQVGDWG 187 SAG E GGVSVYL+E+ATPGRKGFYVSWQS SQQVA++FAA +G L+ L+ ++G+WG Sbjct: 127 SAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWG 186 Query: 188 WRVPFFIGCMIVPVLFVIRRSLQETEEFLARKRKPNLNEIFRSMVENWKLVIAGMMLVSM 247 WRVPF IGC+IVP LF IRRSL+ETEEF RK +P + E+ RSM ENW+L AG +L M Sbjct: 187 WRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAGTLLAVM 246 Query: 248 TTVSFYLITVYTPTFGKNVLKLSTESALIVTFCVGISNFIWLPVMGALSDRIGRRPLLLV 307 TTVSFYLIT YTPTFG+NVL +S +LIVT CVG SN IWLPVMG+LSDRIGRR L+V Sbjct: 247 TTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIV 306 Query: 308 FTILTILTAYPAMTWLVGDATFGKMLVVELWLSFLYASYNGAMVVALTEVMPVDVRTAGF 367 F+ LT+LTAYPAMTWL+ + +FG++L VELWLSFLY YNGAM+V LTE+MP +RT GF Sbjct: 307 FSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGF 366 Query: 368 SLAYSLATAVFGGFTPAIATGLIEITHDKAAPGLWMSFAAVCGLIATLVLYRKK 421 SLAYSLATA+FGGFTPAIATGLI T +KA PGLW+SFAA+CGL+ATL + + + Sbjct: 367 SLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQ 420 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 578 bits (1491), Expect = e-165, Method: Compositional matrix adjust. Identities = 273/420 (65%), Positives = 341/420 (81%) Query: 3 SPTIASSSKFATVLRVTSGNFMEMFDFFLFGFYASYISKAFFPSGDEFASLMLTFMTFGA 62 +P + + F +LRVTSGNF+E FDFFLFGFYA+YI++ FFP+ EFASLMLTF FG+ Sbjct: 5 TPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGS 64 Query: 63 GFLMRPLGAIILGAYVDRVGRRQGLIVTLALMALGTVLIAFVPGYATIGLLAPALVLIGR 122 GFLMRP+GAI+LGAY+DR+GRR+GL+VTLA+M GT+LIA VPGY TIGL APALVL+GR Sbjct: 65 GFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGR 124 Query: 123 LLQGFSAGVELGGVSVYLAEMATPGRKGFYVSWQSASQQVAIIFAAAIGYGLNIWLTKDQ 182 LLQGFSAGVELGGVSVYL+E+ATPG KGFY SWQSASQQVAI+ AA IGY LNI L D Sbjct: 125 LLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDA 184 Query: 183 VGDWGWRVPFFIGCMIVPVLFVIRRSLQETEEFLARKRKPNLNEIFRSMVENWKLVIAGM 242 + +WGWR+PFFIGCMI+P++FV+RRSLQETE FL RK +P+ EIF ++ +NW+++ AG Sbjct: 185 ISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGT 244 Query: 243 MLVSMTTVSFYLITVYTPTFGKNVLKLSTESALIVTFCVGISNFIWLPVMGALSDRIGRR 302 +LV+MTT +FY ITVYTPT+G+ VL LS +LIVT VG+SNFIWLP+ GA+SDRIGRR Sbjct: 245 LLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRR 304 Query: 303 PLLLVFTILTILTAYPAMTWLVGDATFGKMLVVELWLSFLYASYNGAMVVALTEVMPVDV 362 +L+ T+L ++T +P M WL F +M +V LW SF + YNGAMV ALTEVMPV V Sbjct: 305 AVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYV 364 Query: 363 RTAGFSLAYSLATAVFGGFTPAIATGLIEITHDKAAPGLWMSFAAVCGLIATLVLYRKKS 422 RT GFSLA+SLATA+FGG TPAI+T L+++T DK++PG W+ AA+CGL AT +L+ + S Sbjct: 365 RTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVRLS 424 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 548 bits (1413), Expect = e-156, Method: Compositional matrix adjust. Identities = 285/415 (68%), Positives = 349/415 (84%) Query: 7 ASSSKFATVLRVTSGNFMEMFDFFLFGFYASYISKAFFPSGDEFASLMLTFMTFGAGFLM 66 ++ SK + RV SGNF+EM+DF ++GFYA+ I+K FFP + FASLML+ TFGAGFLM Sbjct: 3 SNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLM 62 Query: 67 RPLGAIILGAYVDRVGRRQGLIVTLALMALGTVLIAFVPGYATIGLLAPALVLIGRLLQG 126 RPLGA+ LGAY+DR GRRQGLI+TL LMA+GT+LIAFVPGYAT+G+ AP LVL GRLLQG Sbjct: 63 RPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQG 122 Query: 127 FSAGVELGGVSVYLAEMATPGRKGFYVSWQSASQQVAIIFAAAIGYGLNIWLTKDQVGDW 186 FSAGVELGGVSVYL+E+ATPGRKGF+VSWQSASQQVA++FA +G LN WL+ +G+W Sbjct: 123 FSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEW 182 Query: 187 GWRVPFFIGCMIVPVLFVIRRSLQETEEFLARKRKPNLNEIFRSMVENWKLVIAGMMLVS 246 GWRVPFFIGC+IVP LFVIRRSL+ET EF AR +P+L+++ RS+ +N+ +V+AG +V Sbjct: 183 GWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVV 242 Query: 247 MTTVSFYLITVYTPTFGKNVLKLSTESALIVTFCVGISNFIWLPVMGALSDRIGRRPLLL 306 MTTVSFYLIT YTPTFGKN L+LS +L+VT C+G+SNFIWLPVMGA SDRIGR+PLLL Sbjct: 243 MTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLL 302 Query: 307 VFTILTILTAYPAMTWLVGDATFGKMLVVELWLSFLYASYNGAMVVALTEVMPVDVRTAG 366 + L +LTAYPA++WLV + +F +L VELWLSFLY+SYNGAMVVALTEVMP DVRT G Sbjct: 303 GASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTG 362 Query: 367 FSLAYSLATAVFGGFTPAIATGLIEITHDKAAPGLWMSFAAVCGLIATLVLYRKK 421 FSLAYSLATA FGGFTPA+ T LI ++AAPG+W+S AA+ GL+ATLVL+R++ Sbjct: 363 FSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIWLSGAALLGLLATLVLFRRR 417 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 282 bits (722), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 164/421 (38%), Positives = 240/421 (57%), Gaps = 2/421 (0%) Query: 7 ASSSKFATVLRVTSGNFMEMFDFFLFGFYASYISKAFFPSGDEFASLMLTFMTFGAGFLM 66 + +S+ V GN +E +DF ++GF +S I++ FFPSGDE+ SL++ TFG GF M Sbjct: 6 SGTSRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFM 65 Query: 67 RPLGAIILGAYVDRVGRRQGLIVTLALMALGTVLIAFVPGYATIGLLAPALVLIGRLLQG 126 RP+G ++LG Y DR GR+ + + + LM L +IAF P YA IG+ AP L++I R+LQG Sbjct: 66 RPVGGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQG 125 Query: 127 FSAGVELGGVSVYLAEMATPGRKGFYVSWQSASQQVAIIFAAAIGYGLNIWLTKDQVGDW 186 F+ G E + +L E A P R+G Y SWQ Q +A+ A +G + L + + W Sbjct: 126 FATGGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESW 185 Query: 187 GWRVPFFIGCMIVPVLFVIRRSLQETEEFLARKRKPNLNEIFRSMVENWKL-VIAGMMLV 245 GWRVPF G +I PV IRR + ETE FL R+P + ++ ++ V+ M L Sbjct: 186 GWRVPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLT 245 Query: 246 SMTTVSFYLITVYTPTFGKNVLKLSTESALIVTFCVGISNFIWLPVMGALSDRIGRRPLL 305 + TVSFY++ V PTF L L + +V + +P+ G LSDR+GRRP+L Sbjct: 246 VVGTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVL 305 Query: 306 LVFTILTILTAYPAMTWLVGDATFGKMLVVELWLSFLYASYNGAMVVALTEVMPVDVRTA 365 LV T+ +L YP W+ + G++L+++L L + G A+ E PV VR+ Sbjct: 306 LVATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRST 365 Query: 366 GFSLAYSLATAVFGGFTPAIATGLIEITHDKAAPGLWMSFAAVCGLIATLVLYRKKSLAV 425 G ++AY+LA +FGGF P I T L E+ AP ++ AA GL+ATL L R+ + Sbjct: 366 GLAVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYL-REGATPA 424 Query: 426 P 426 P Sbjct: 425 P 425