BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0035.p (478 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2848 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Rs... 430 e-120 PM0138 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Pmu... 309 1e-83 PA4416 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Pae... 306 7e-83 NMB0416 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Nm... 298 1e-80 NMA2068 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Nm... 286 1e-76 >RSc2848 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Rso Ralstonia solanacearum Length = 482 Score = 430 bits (1106), Expect = e-120, Method: Compositional matrix adjust. Identities = 263/467 (56%), Positives = 316/467 (67%), Gaps = 25/467 (5%) Query: 26 DVSINGATTDSRAVVPGNLFIALRGERFDAHDFLDAVAAQGAAAVVVERVPAGLK----I 81 D +I TTDSRAV+PG+LF+AL GERFDAHDFL V A+GAAAV+V R P G+ + Sbjct: 27 DAAIRRVTTDSRAVLPGDLFVALIGERFDAHDFLPDVVARGAAAVLVSRPPVGIPDLSGV 86 Query: 82 PAIVVSDTRVALGRIARHWRQQFKLPLIAVTGSNGKTTVKEMIASILAADFGEDRSMATR 141 + V+DTR+ALG++A WR++F +P++AVTGSNGKTTVKEMI+++ A GE +AT Sbjct: 87 AVLTVADTRIALGQLAAGWRRRFPIPVVAVTGSNGKTTVKEMISAVFACAVGEAARLATA 146 Query: 142 GNFNNEIGVPLTLFRLQPQHQAAVVELGMNHPGEIAVLAEIARPTLALVNNAQREHQEFM 201 GN NN+IG+PLTLFRL QH+ AV+ELGMNHPGE VLA IA+PT+AL+NNAQREHQEFM Sbjct: 147 GNLNNDIGLPLTLFRLTAQHRLAVLELGMNHPGETEVLAAIAQPTVALINNAQREHQEFM 206 Query: 202 ATVEAVARENGAVFAALPADGIAVFPAE----DDYAWVWREIAGARPVISFGLNPDANVS 257 +VEAVA E+ AV AALPADG+AVFP + +YA +WR AG R V+ FG+ A VS Sbjct: 207 VSVEAVAAEHAAVLAALPADGVAVFPRDAANGGEYAPLWRAAAGTRRVLDFGIEGGA-VS 265 Query: 258 ATYQVREFGSAIAVNADIDGRSQQFGIKLAAVGEHNVRNALAATACALGAGIAVAAIVRG 317 A G I D+ +F L +G HN RNALAATACAL AGIA I + Sbjct: 266 AAVTDTADGQRI----DVHAPGLRFSFTLPLLGVHNARNALAATACALAAGIAPEVIAQA 321 Query: 318 LEAFAPVNGRLQRKAAASGALVIDDTYNANPDSVRAAIDVLAQTVAPRVLALGDMGEVGN 377 L AFAPV GRLQRK G LVIDDTYNANPDSVRAAID LA APR L LGDMGEVG Sbjct: 322 LSAFAPVKGRLQRKPGHHGGLVIDDTYNANPDSVRAAIDALATLPAPRWLVLGDMGEVGT 381 Query: 378 EGPKFHREIGAYARARGIEHFFGFGDAMRDAIEAYNSAPGAAFPARHFDTVDAIGAATRE 437 +GP FHREIGAYAR RGI+ G+ R +EA+ ARHF + +A+ Sbjct: 382 QGPAFHREIGAYARERGIDAVLATGELARHMVEAFGGG------ARHFASAEALIEQGVP 435 Query: 438 VAVAAATVLVKGSRFMKMERVVQHLV------GAQLQTGAPLHQETH 478 ATVLVKGSRFM+MER+V LV +Q G Q+TH Sbjct: 436 AIAPGATVLVKGSRFMRMERIVDALVLKDPAADSQGAPGTTHTQQTH 482 >PM0138 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Pmu Pasteurella multocida Length = 460 Score = 309 bits (791), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 179/441 (40%), Positives = 253/441 (57%), Gaps = 10/441 (2%) Query: 25 ADVSINGATTDSRAVVPGNLFIALRGERFDAHDFLDAVAAQGAAAVVVERVPAGLKIPAI 84 A+V + +TD+R V +LF AL+GE FDAH++LD AQGA A+VVER + +P + Sbjct: 21 ANVVVENISTDTRQRVASSLFFALKGEHFDAHNYLDKAVAQGANALVVERADTQISVPQL 80 Query: 85 VVSDTRVALGRIARHWRQQFKLPLIAVTGSNGKTTVKEMIASILAADFGEDRSMATRGNF 144 +V DTR+ALG +A+ +QQ +A+TGS+GKTTVKEM ASIL + G ++ + T+GNF Sbjct: 81 IVKDTRIALGELAKWVKQQVNPRTLAMTGSSGKTTVKEMTASILQSAVGVEQVLFTQGNF 140 Query: 145 NNEIGVPLTLFRLQPQHQAAVVELGMNHPGEIAVLAEIARPTLALVNNAQREHQEFMATV 204 NN+IGVPLTL RL QHQ AV+ELG NH GEIA + +P +ALVNN H E ++ Sbjct: 141 NNDIGVPLTLLRLTEQHQFAVIELGANHQGEIAYTTGLVQPNVALVNNVAAAHLEGFGSL 200 Query: 205 EAVARENGAVFAALPADGIAVFPAEDDYAWVWREIAGARPVISFGLNPD-ANVSATYQV- 262 E VA G ++ L DG+A+ E DY W + GA V F + A+ A + Sbjct: 201 EGVATAKGEIYRGLQPDGVAIINKEHDYRSTWAQDIGAHRVQYFAYQDNTADFYADNVIF 260 Query: 263 REFGSAIAVNADIDGRSQQFGIKLAAVGEHNVRNALAATACALGAGIAVAAIVRGLEAFA 322 E GS D+ + I L +GEHNV+NALAA+A A+ G +A I +GLE Sbjct: 261 HEAGSTF----DLCTPQGKTTIHLPYLGEHNVKNALAASALAMNVGATLAQIKQGLEVRT 316 Query: 323 PVNGRLQRKAAASGALVIDDTYNANPDSVRAAIDVLAQTVAPRVLALGDMGEVGNEGPKF 382 V GRL L++DDTYNAN DS+++AI VL + A R+L +GDM E+G Sbjct: 317 QVKGRLYPVQPCDNLLLLDDTYNANVDSLQSAIRVLQKYDAFRILVVGDMAELGENSQIC 376 Query: 383 HREIGAYARARGIEHFFGFGDAMRDAIEAYNSAPGAAFPARHFDTVDAIGAATREVAVAA 442 H+++ A+A +E + FG ++ + G F + + + ++ Sbjct: 377 HQQVAECAKAAKLERVYSFGS---ESAVISQACLGKHFTDKALLCRELTQLLSEKLKENQ 433 Query: 443 ATVLV-KGSRFMKMERVVQHL 462 VL+ KGSR M+ME V+ L Sbjct: 434 KIVLLAKGSRRMQMEDVINTL 454 >PA4416 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Pae Pseudomonas aeruginosa Length = 458 Score = 306 bits (784), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 199/468 (42%), Positives = 271/468 (57%), Gaps = 20/468 (4%) Query: 5 LEQLKQWLDGATVHNDAGALADVSINGATTDSRAVVPGNLFIALRGERFDAHDFLDAVAA 64 L QL LD + DA + +TDSRA+ PG LFIAL G RFD HD+L VAA Sbjct: 7 LSQLTVALDARLIGEDA------VFSAVSTDSRAIGPGQLFIALSGPRFDGHDYLAEVAA 60 Query: 65 QGAAAVVVERVPAGLKIPAIVVSDTRVALGRIARHWRQQFKLPLIAVTGSNGKTTVKEMI 124 +GA A +VER A +P ++V DTR ALGR+ R++F PL A+TGS+GKTTVKEM+ Sbjct: 61 KGAVAALVEREVADAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEML 120 Query: 125 ASILAADFGEDRS-MATRGNFNNEIGVPLTLFRLQPQHQAAVVELGMNHPGEIAVLAEIA 183 ASIL G+ S +ATRGN NN++GVPLTL +L PQH++AV+ELG + GEIA E+ Sbjct: 121 ASILRTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVELT 180 Query: 184 RPTLALVNNAQREHQEFMATVEAVARENGAVFAALPADGIAVFPAEDDYAWVWREIAGAR 243 RP +A++ NA H E + G + L ADG AV +D W+ A R Sbjct: 181 RPHVAIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGR 240 Query: 244 PVISFGLN-PDANVSATYQVREFGSAIAVNADIDGRSQQFGIKLAAVGEHNVRNALAATA 302 P+++F L+ P A+ A R+ + + G + + ++L +G HNV NALAA A Sbjct: 241 PLLTFSLDRPQADFRAADLQRDARGCMGFR--LQGVAGEAQVQLNLLGRHNVANALAAAA 298 Query: 303 CALGAGIAVAAIVRGLEAFAPVNGRLQRKAAASGALVIDDTYNANPDSVRAAIDVLAQTV 362 A G+ + IV GL+A PV GR + ASG VIDD+YNANP S+ AAID+L+ Sbjct: 299 AAHALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGFS 358 Query: 363 APRVLALGDMGEVGNEGPKFHREIGAYARARGIEHFFGFGDAMRDAIEAYNSAPGAAFPA 422 VL LGDMGE+G+ + HRE+GAYA + + + G M A++A+ + Sbjct: 359 GRTVLVLGDMGELGSWAEQAHREVGAYAAGK-VSALYAVGPLMAHAVQAFGAT------G 411 Query: 423 RHF-DTVDAIGAATREVAVAAATVLVKGSRFMKMERVVQHLVGAQLQT 469 RHF D IGA E T+L+KGSR M++VV L G+ ++ Sbjct: 412 RHFADQASLIGALATEQPT--TTILIKGSRSAAMDKVVAALCGSSEES 457 >NMB0416 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase Nme Neisseria meningitidis MC58 Length = 455 Score = 298 bits (764), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 194/434 (44%), Positives = 263/434 (60%), Gaps = 15/434 (3%) Query: 34 TDSRAVVPGNLFIALRGERFDAHDFLDAVAAQGAAAVVVERVPAGLKIPAIVVSDTRVAL 93 TDSR + G++F AL GERFDAHDF++ V A GAAAVVV R A+ V DT AL Sbjct: 29 TDSRDIRAGDVFFALAGERFDAHDFVEDVLAAGAAAVVVSREDCAAMDGALKVDDTLAAL 88 Query: 94 GRIARHWRQQFKLPLIAVTGSNGKTTVKEMIASILAADFGEDRSMATRGNFNNEIGVPLT 153 +A+ WR+ + +TGS GKTTVKEM+A++L FG+D +AT GNFNN IG+PLT Sbjct: 89 QTLAKAWRENVNPFVFGITGSGGKTTVKEMLAAVLRRRFGDDAVLATAGNFNNHIGLPLT 148 Query: 154 LFRLQPQHQAAVVELGMNHPGEIAVLAEIARPTLALVNNAQREHQEF-MATVEAVARENG 212 L +L +H+ AV+E+GMNH GE+AVL +IA+P ALVNNA R H V +A+ Sbjct: 149 LLKLNEKHRYAVIEMGMNHFGELAVLTQIAKPNAALVNNAMRAHVGCGFDGVGDIAKAKS 208 Query: 213 AVFAALPADGIAVFPAEDDYAWVWREIAGARPVISFGLNPDANVSATYQVREFGSAIAVN 272 ++ L +DGIA+ P ED V++ +FG++ +V A V + ++ Sbjct: 209 EIYQGLCSDGIALIPQEDANMAVFKTATLNLNTRTFGIDS-GDVHAENIVLK---PLSCE 264 Query: 273 ADIDGRSQQFGIKLAAVGEHNVRNALAATACALGAGIAVAAIVRGLEAFAPVNGRLQRKA 332 D+ ++ + L G HNV NA AA A AL AG+++ + GL+ F+ + GRL K+ Sbjct: 265 FDLVCGDERAAVVLPVPGRHNVHNAAAAAALALAAGLSLNDVAEGLKGFSNIKGRLNVKS 324 Query: 333 AASGALVIDDTYNANPDSVRAAIDVLAQTVAPRVLALGDMGEVG----NEGPKFHREIGA 388 GA +IDDTYNANPDS++AAIDVLA+ APR+ +GDMGE+G +E H E+GA Sbjct: 325 GIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFVMGDMGELGELGEDEAAAMHAEVGA 384 Query: 389 YARARGIEHFFGFGDAMRDAIEAYNSAPGAAFPARHFDTVDAIGAATREVAVAAATVLVK 448 YAR +GIE + GD +A E + A G F A+ D + R ATVLVK Sbjct: 385 YARDQGIEAAYFVGDNSVEAAEKF-GADGLWFAAK-----DPLIQVLRHDLPERATVLVK 438 Query: 449 GSRFMKMERVVQHL 462 GSRFM+ME VV+ L Sbjct: 439 GSRFMQMEEVVEAL 452 >NMA2068 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase NmA Neisseria meningitidis Z2491 Length = 452 Score = 286 bits (731), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 189/431 (43%), Positives = 262/431 (60%), Gaps = 12/431 (2%) Query: 34 TDSRAVVPGNLFIALRGERFDAHDFLDAVAAQGAAAVVVERVPAGLKIPAIVVSDTRVAL 93 TDSR + G++F AL G RFDAHDF++ V A GAAAVVV R A+ V DT AL Sbjct: 29 TDSRDIRAGDVFFALAGGRFDAHDFVEDVLAAGAAAVVVSREDCVAMDGALKVDDTLTAL 88 Query: 94 GRIARHWRQQFKLPLIAVTGSNGKTTVKEMIASILAADFGEDRSMATRGNFNNEIGVPLT 153 +A+ WR+ + +TGS GKTTVKEM+A++L FG++ +AT GNFNN IG+PLT Sbjct: 89 QMLAKAWRENVNPFVFGITGSGGKTTVKEMLAAVLRRRFGDNAVLATAGNFNNHIGLPLT 148 Query: 154 LFRLQPQHQAAVVELGMNHPGEIAVLAEIARPTLALVNNAQREHQEF-MATVEAVARENG 212 L +L +H+ AV+E+GMNH GE+AVL +IA+P ALVNNA R H V +A+ Sbjct: 149 LLKLNEKHRYAVIEMGMNHFGELAVLTQIAKPDAALVNNAMRAHVGCGFDGVGDIAKAKS 208 Query: 213 AVFAALPADGIAVFPAEDDYAWVWREIAGARPVISFGLNPDANVSATYQVREFGSAIAVN 272 ++ L +DG+A+ P ED V++ +FG++ +V A V + ++ Sbjct: 209 EIYQGLCSDGMALIPQEDANMAVFKTATLNLNTRTFGIDS-GDVHAENIVLK---PLSCE 264 Query: 273 ADIDGRSQQFGIKLAAVGEHNVRNALAATACALGAGIAVAAIVRGLEAFAPVNGRLQRKA 332 D+ ++ + L G HNV NA AA A +L AG+++ + GL+ F+ + GRL K+ Sbjct: 265 FDLVCGNECAAVVLPVPGRHNVHNAAAAAALSLAAGLSLNDVAEGLKGFSNIKGRLNVKS 324 Query: 333 AASGALVIDDTYNANPDSVRAAIDVLAQTVAPRVLALGDMGEVG-NEGPKFHREIGAYAR 391 GA +IDDTYNANPDS++AA+DVLA+ APR+ +GDMGE+G +E H E+GAYAR Sbjct: 325 GIKGATLIDDTYNANPDSMKAAVDVLARMPAPRIFVMGDMGELGEDEAAAMHAEVGAYAR 384 Query: 392 ARGIEHFFGFGDAMRDAIEAYNSAPGAAFPARHFDTVDAIGAATREVAVAAATVLVKGSR 451 +GIE + GD +A E + A G F A+ D + R ATVLVKGSR Sbjct: 385 DQGIEAAYFVGDNSVEAAEKF-GADGLWFAAK-----DPLIQVLRHDLPERATVLVKGSR 438 Query: 452 FMKMERVVQHL 462 FM+ME VV+ L Sbjct: 439 FMQMEEVVEAL 449