BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0449.p (296 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3261 [GER] COG0697 Permeases of the drug/metabolite transport... 276 4e-74 ECs2140 [GER] COG0697 Permeases of the drug/metabolite transport... 231 2e-60 STM1517 [GER] COG0697 Permeases of the drug/metabolite transport... 222 1e-57 ydeD [GER] COG0697 Permeases of the drug/metabolite transporter ... 207 2e-53 ZydeD [GER] COG0697 Permeases of the drug/metabolite transporter... 203 3e-52 >RSc3261 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 308 Score = 276 bits (706), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 160/300 (53%), Positives = 214/300 (71%), Gaps = 9/300 (3%) Query: 1 MRPAHVALVLLVILVWGVNFAIIKVGLNGVPPLLLGTLRFLLAAFPALLFVRPPKLPLRL 60 M P + L L V+LVWGVNF IIKVGL+GVPP+LLG LRF L AFPA+LFV PK+ L+ Sbjct: 11 MSPKDLLLALTVVLVWGVNFVIIKVGLHGVPPMLLGALRFALVAFPAILFVPRPKIALKW 70 Query: 61 YLAFGLTMSVGQFAFLFSAIHVGMPSGLASLVLQSQSFFTLLLTVLWLREKWQANQLAGL 120 LA+G T+S GQFAFLFSA++VGMP+GLASLVLQSQ+FFTL + + LRE + LAG+ Sbjct: 71 LLAYGATISFGQFAFLFSAMYVGMPAGLASLVLQSQAFFTLTIAAVVLREPIRWYHLAGM 130 Query: 121 ALAAAGLILIG----SAHGA--NMPLNGFLLTIAAAAMWACGNIVSRAVGRHGPINQVAF 174 A+AA GL +IG S GA M GFLLT+ AA W+ GNIV++ R GP+N V+ Sbjct: 131 AVAACGLAMIGVAGTSGAGAATGMTTAGFLLTLCAALSWSSGNIVTK---RIGPVNVVSL 187 Query: 175 VVWASLVPPLPLLLLSWLIEGPAAIGSALQHFSLQSFAAVAYIAWASTLFGYAVWNFLMS 234 VVW +L+PP+P LLS+ +EGP I +L + S A+ Y+A+ +T+FGY++W+ L++ Sbjct: 188 VVWGALIPPVPFFLLSYWMEGPQQIAHSLANLGGTSIGAIVYLAFGATIFGYSLWSRLLA 247 Query: 235 RYAVNRIAPFTLLVPLVGLTTGWLAFGEALQAVHLIGGALLMVGLIVNLFGAPLLAKLRL 294 RYA +++AP TLLVP+VGL + L GE L +GGA++M GL++N+FG L A+L L Sbjct: 248 RYAASQVAPLTLLVPVVGLVSAALLLGERLVPAQWLGGAVVMAGLLLNVFGGRLAARLAL 307 >ECs2140 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 299 Score = 231 bits (588), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 122/273 (44%), Positives = 183/273 (67%), Gaps = 3/273 (1%) Query: 16 WGVNFAIIKVGLNGVPPLLLGTLRFLLAAFPALLFVRPPKLPLRLYLAFGLTMSVGQFAF 75 WG+NF +IKVGL+ +PPL+L LRF+L AFPA+ FV PK+PL L L +GLT+S QFAF Sbjct: 16 WGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLNLLLGYGLTISFAQFAF 75 Query: 76 LFSAIHVGMPSGLASLVLQSQSFFTLLLTVLWLREKWQANQLAGLALAAAGLILI--GSA 133 LF AI+ GMP+GLASLVLQ+Q+FFT++L E+ QLAG+ALA +G++++ S Sbjct: 76 LFCAINFGMPAGLASLVLQAQAFFTIVLGAFTFGERLHGKQLAGIALAISGVLVLIEDSF 135 Query: 134 HGANMPLNGFLLTIAAAAMWACGNIVSRAVGRHGPINQV-AFVVWASLVPPLPLLLLSWL 192 +G ++ + GF+LT+AAA WA GNI ++ + H V + VVW++L+P +P + S + Sbjct: 136 NGQHVAMLGFMLTLAAAFSWASGNIFNKKIMSHSSRPAVMSLVVWSALIPIIPFFVASLI 195 Query: 193 IEGPAAIGSALQHFSLQSFAAVAYIAWASTLFGYAVWNFLMSRYAVNRIAPFTLLVPLVG 252 ++G + +L + + A+ Y+A+ +T+ GY +W L+ RY R+AP +LLVP+VG Sbjct: 196 LDGSGKMIHSLVTIDMTTILALMYLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVG 255 Query: 253 LTTGWLAFGEALQAVHLIGGALLMVGLIVNLFG 285 L + L E L + +G L+M GL +N+FG Sbjct: 256 LASAALLLDERLTGLQFLGAVLIMAGLYINVFG 288 >STM1517 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 300 Score = 222 bits (565), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 139/281 (49%), Positives = 195/281 (69%), Gaps = 3/281 (1%) Query: 8 LVLLVILVWGVNFAIIKVGLNGVPPLLLGTLRFLLAAFPALLFVRPPKLPLRLYLAFGLT 67 L LLV++VWG+NF +IKVGL+ +PPLLL LRFLL AFPA+ FV PK+PL L L +GLT Sbjct: 9 LALLVVVVWGLNFVVIKVGLHHMPPLLLAGLRFLLVAFPAIFFVARPKVPLTLLLGYGLT 68 Query: 68 MSVGQFAFLFSAIHVGMPSGLASLVLQSQSFFTLLLTVLWLREKWQANQLAGLALAAAGL 127 +S GQFAFLF AI GMP+GLASLVLQ+Q+FFT+ L E+ Q QLAG+ALA G+ Sbjct: 69 ISFGQFAFLFCAIKFGMPAGLASLVLQAQAFFTMALGAFVFSERLQRKQLAGIALAIIGV 128 Query: 128 ILI--GSAHGANMPLNGFLLTIAAAAMWACGNIVSRAVGRHGPINQV-AFVVWASLVPPL 184 +++ S +G ++ ++GF+LT+AAA WACGNI ++ + +H P V + VVW++L+P L Sbjct: 129 LVLIEASLNGQHIAMSGFMLTLAAAFSWACGNIFNKKIMQHSPRPAVMSLVVWSALIPIL 188 Query: 185 PLLLLSWLIEGPAAIGSALQHFSLQSFAAVAYIAWASTLFGYAVWNFLMSRYAVNRIAPF 244 P LL S L+EG I +L + + ++ Y+A+ +T+ GY +W L+ RY R+AP Sbjct: 189 PFLLSSLLLEGADHITQSLITIDMTTILSLLYLAFVATILGYGIWGALLGRYETWRVAPL 248 Query: 245 TLLVPLVGLTTGWLAFGEALQAVHLIGGALLMVGLIVNLFG 285 +LLVP+VGL + + GE L + L G L+M GL +N+FG Sbjct: 249 SLLVPVVGLASAAVLLGETLTGMQLAGAVLIMAGLYINVFG 289 >ydeD [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 266 Score = 207 bits (527), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 110/255 (43%), Positives = 168/255 (65%), Gaps = 3/255 (1%) Query: 34 LLGTLRFLLAAFPALLFVRPPKLPLRLYLAFGLTMSVGQFAFLFSAIHVGMPSGLASLVL 93 +L LRF+L AFPA+ FV PK+PL L L +GLT+S QFAFLF AI+ GMP+GLASLVL Sbjct: 1 MLAGLRFMLVAFPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVL 60 Query: 94 QSQSFFTLLLTVLWLREKWQANQLAGLALAAAGLILI--GSAHGANMPLNGFLLTIAAAA 151 Q+Q+FFT++L E+ QLAG+ALA G++++ S +G ++ + GF+LT+AAA Sbjct: 61 QAQAFFTIMLGAFTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAF 120 Query: 152 MWACGNIVSRAVGRHGPINQV-AFVVWASLVPPLPLLLLSWLIEGPAAIGSALQHFSLQS 210 WACGNI ++ + H V + V+W++L+P +P + S +++G A + +L + + Sbjct: 121 SWACGNIFNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLILDGSATMIHSLVTIDMTT 180 Query: 211 FAAVAYIAWASTLFGYAVWNFLMSRYAVNRIAPFTLLVPLVGLTTGWLAFGEALQAVHLI 270 ++ Y+A+ +T+ GY +W L+ RY R+AP +LLVP+VGL + L E L + + Sbjct: 181 ILSLMYLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFL 240 Query: 271 GGALLMVGLIVNLFG 285 G L+M GL +N+FG Sbjct: 241 GAVLIMTGLYINVFG 255 >ZydeD [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 266 Score = 203 bits (517), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 110/255 (43%), Positives = 167/255 (65%), Gaps = 3/255 (1%) Query: 34 LLGTLRFLLAAFPALLFVRPPKLPLRLYLAFGLTMSVGQFAFLFSAIHVGMPSGLASLVL 93 +L LRF+L AFPA+ FV PK+PL L L +GLT+S QFAFLF AI+ GMP+GLASLVL Sbjct: 1 MLAGLRFMLVAFPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVL 60 Query: 94 QSQSFFTLLLTVLWLREKWQANQLAGLALAAAGLILI--GSAHGANMPLNGFLLTIAAAA 151 Q+Q+FFT++L E+ QLAG+ALA +G++++ S +G ++ + GF+LT+AAA Sbjct: 61 QAQAFFTIVLGAFTFGERLHGKQLAGIALAISGVLVLIEDSFNGQHVAMLGFMLTLAAAF 120 Query: 152 MWACGNIVSRAVGRHGPINQV-AFVVWASLVPPLPLLLLSWLIEGPAAIGSALQHFSLQS 210 WA GNI ++ + H V + VVW++L+P +P + S +++G + +L + + Sbjct: 121 SWASGNIFNKKIMSHSSRPAVMSLVVWSALIPIIPFFVASLILDGSGKMIHSLVTIDMTT 180 Query: 211 FAAVAYIAWASTLFGYAVWNFLMSRYAVNRIAPFTLLVPLVGLTTGWLAFGEALQAVHLI 270 A+ Y+A+ +T+ GY +W L+ RY R+AP +LLVP+VGL + L E L + + Sbjct: 181 ILALMYLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFL 240 Query: 271 GGALLMVGLIVNLFG 285 G L+M GL +N+FG Sbjct: 241 GAVLIMAGLYINVFG 255