BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0391.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1286 [GEPR] COG0477 Permeases of the major facilitator superfa... 335 1e-91 SMc02603 [GEPR] COG0477 Permeases of the major facilitator super... 319 1e-86 AGc1918 [GEPR] COG0477 Permeases of the major facilitator superf... 312 1e-84 NMA0047 [GEPR] COG0477 Permeases of the major facilitator superf... 194 3e-49 AGl3235 [GEPR] COG0477 Permeases of the major facilitator superf... 111 3e-24 >PA1286 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 399 Score = 335 bits (859), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 203/387 (52%), Positives = 261/387 (67%), Gaps = 3/387 (0%) Query: 13 VLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVFGPFAGMAAD 72 +LL+ L+L L++GVRHG G +L P+S GW RE F+ AIALQNL+WG+ PF G AD Sbjct: 8 ILLSGALILALSLGVRHGFGLFLAPMSADFGWGREVFAFAIALQNLVWGLAQPFTGALAD 67 Query: 73 RYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAISGIVGRSAP 132 RYG AR +++G LLY GL+ M L ++ +G+LIG LS T+F I G VGR+ P Sbjct: 68 RYGAARAVLVGGLLYALGLVLMGLSQSASGLSLSAGLLIGLGLSGTSFSVILGAVGRAVP 127 Query: 133 PEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMVPMAFRLREP 192 E+RS+A GISSAAGSFGQF M+P LI GW A L+VA++VP+A +++ Sbjct: 128 AEQRSMAMGISSAAGSFGQFAMLPGTLGLIGWLGWSSALL-ALGLLVALIVPLAGLMKDR 186 Query: 193 KLAHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYLKDKGLMDPNI 252 L G EQS+ EA REA A+ F L G+FVCGFQVVFIG HLP+YL D+ L + Sbjct: 187 PLPPQG-HEQSLGEALREACAHSGFWLLALGFFVCGFQVVFIGVHLPAYLVDQHL-PAQV 244 Query: 253 AVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAPLSSWSVYIFS 312 LAL+GLFN+FG+Y AG LGG K LL+ +Y R V I LFL PLS +S Y F Sbjct: 245 GTTVLALVGLFNVFGTYIAGWLGGRWSKPRLLTALYLVRGVVIVLFLWLPLSVYSAYAFG 304 Query: 313 AAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGGYLFTREGSYN 372 AMGLLWLSTVPLTNG +A +FG+++LSML G VFL HQ+G+FLG WLGG ++ R GSY+ Sbjct: 305 VAMGLLWLSTVPLTNGTVATLFGVRNLSMLGGIVFLFHQLGAFLGGWLGGVVYDRTGSYD 364 Query: 373 TVWMITIGLGLFATVMNLPVNEKAIRR 399 VW ++I L L A ++N PV E+ + R Sbjct: 365 LVWQLSILLSLLAALLNWPVRERPVAR 391 >SMc02603 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 412 Score = 319 bits (817), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 178/392 (45%), Positives = 253/392 (64%), Gaps = 9/392 (2%) Query: 13 VLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVFGPFAGMAAD 72 +++A ++ L G R +GF+ P+ GW R TF LA+A QNL WG+ PF G AD Sbjct: 21 IIVAGSIIAMLTFGPRSAMGFFQLPMLAEKGWDRTTFGLAMAFQNLCWGLGQPFFGAIAD 80 Query: 73 RYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAISGIVGRSAP 132 ++GT RV+ + L+Y GL+ MA D P+ +G GVL+G ++ +FG + R+ Sbjct: 81 KFGTWRVLALSGLVYAAGLILMAFADAPIWLHIGGGVLVGLGVASGSFGIVLSAFARNVA 140 Query: 133 PEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMVPMAFRLREP 192 PE+RSLAFGI +AAGS G F+ P+ Q LIS GW + L L + +++ F + Sbjct: 141 PEQRSLAFGIGTAAGSAGMFLFAPLSQGLISAYGWSDS---LVYLGLLMLLVPLFAIPLR 197 Query: 193 KLAHSGKQ-----EQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYLKDKGL 247 A SG+Q +Q++ EA +EA ++ + L++G+FVCG+QV FI AH P+Y+ D G+ Sbjct: 198 GNASSGRQSEALFKQTVGEALKEALGHKSYLLLVSGFFVCGYQVAFITAHFPAYIGDIGI 257 Query: 248 MDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAPLSSWS 307 D AV ALALIG FNI GS+ AG +G K Y L+ IY +R+V +S FLL P + S Sbjct: 258 -DARYAVIALALIGFFNIIGSFSAGIIGQRYSKPYFLALIYLARSVVVSAFLLLPQTPTS 316 Query: 308 VYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGGYLFTR 367 V +F+ MGLLWLSTVP TNG++A +FG +HL +L G VFLSHQIGSFLGVW+GGYL+ Sbjct: 317 VIVFAVVMGLLWLSTVPPTNGLVAIMFGTRHLGLLGGIVFLSHQIGSFLGVWMGGYLYDH 376 Query: 368 EGSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 GSY+ VW + + LG+FA +++ P+ E+A+ R Sbjct: 377 FGSYDPVWWVGVALGVFAAIVHWPIEERAVAR 408 >AGc1918 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 414 Score = 312 bits (799), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 177/391 (45%), Positives = 250/391 (63%), Gaps = 7/391 (1%) Query: 13 VLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVFGPFAGMAAD 72 ++ A L+ + G R +GF+ P+ GW R TF LA+ALQNL WG+ PF G AD Sbjct: 23 IIAAGSLIAVMTFGPRSAMGFFQLPMLADTGWDRSTFGLAMALQNLFWGLGQPFFGAIAD 82 Query: 73 RYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAISGIVGRSAP 132 +YGT RV+V+ +LY GL+ M+ P G GVL+G ++ +F I R Sbjct: 83 KYGTGRVLVLSGILYAAGLVCMSFGTSPFWLHFGGGVLVGLGIAAGSFSVILSAFARHVT 142 Query: 133 PEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMVPM-AFRLR- 190 P++RSLAFGI +AAGS G F+ P+ Q LIS GW + WL+A++V +VP+ A+ +R Sbjct: 143 PQQRSLAFGIGTAAGSAGMFLFAPISQGLISAYGWSDSLVWLAAMMV--LVPLLAWPMRG 200 Query: 191 --EPKLAHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYLKDKGLM 248 + +Q++ EA +EA ++ + L G+FVCGFQV FI AH P+YL D G+ Sbjct: 201 NSSSGSQSQAQFQQTVGEALKEALGHKSYLLLTTGFFVCGFQVAFITAHFPAYLGDIGI- 259 Query: 249 DPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAPLSSWSV 308 +P AV A+ALIG FNI GS AG + K YLL+ IY +R+V ++ FLL P S SV Sbjct: 260 EPRYAVIAMALIGFFNIIGSLAAGVIAQRYSKPYLLAYIYIARSVVVTAFLLLPQSPLSV 319 Query: 309 YIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGGYLFTRE 368 +F++ MG+LWLSTVP TN ++A +FG +HL ML G VFL+HQIGSFLGVWLGG+L+ R Sbjct: 320 ILFASFMGILWLSTVPPTNALVAIMFGTRHLGMLGGVVFLTHQIGSFLGVWLGGFLYDRF 379 Query: 369 GSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 G+Y+ VW + +G+G+FA +++ P+ E+ R Sbjct: 380 GTYDIVWWLGVGMGIFAAIVHWPIQERPAPR 410 >NMA0047 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 405 Score = 194 bits (493), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 135/402 (33%), Positives = 211/402 (52%), Gaps = 10/402 (2%) Query: 1 MFHS-ERAPDFKTVLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLM 59 M H+ + P F + A+ +L + +G+R LG ++QP+ + FSL IA+ LM Sbjct: 1 MTHTASKTPKFWLTITAAAFILLITIGMRMTLGLFVQPVVNTTELSIAQFSLIIAVFQLM 60 Query: 60 WGVFGPFAGMAADRYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTA 119 WGV P +G ADR+G RV+ GA+L + L + + G+L+ Sbjct: 61 WGVSQPLSGALADRFGAFRVLSGGAVLLVCACLIAPNIPTYWGLMIAVGLLLAFGTGSGG 120 Query: 120 FGAISGIVGRSAPPEKRSLAFGISSAAGSFGQFVMMPVEQQLISV--TGWQQAFYWLSAL 177 F I G V P KR LA G+ +A GS GQF+ P+ Q L+ + GW FY A+ Sbjct: 121 FSIIMGQVAAQVPAHKRGLASGLVNAGGSAGQFLFAPLVQGLVVLPEVGWTGTFYVWGAI 180 Query: 178 VVAVMVPMAFRLRE-PKLAHSGKQE----QSIWEATREAFAYRPFQFLIAGYFVCGFQVV 232 + + +P+++ L AH+ + QS+ EA + AF + L +F CGF + Sbjct: 181 AL-LTLPVSWWLAGGNNAAHTQHAQATHGQSLGEAVKTAFKTPSYILLHLSFFACGFHIA 239 Query: 233 FIGAHLPSYLKDKGLMDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRT 292 F+ HLP+ + GL +A ++A+IGL NI G ++G + +Y+L +Y SR Sbjct: 240 FLVTHLPTEVALCGL-PATVASTSIAIIGLANIAGCIFSGWCTSRVRGKYVLFGLYASRA 298 Query: 293 VAISLFLLAPLSSWSVYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQI 352 I +++ +P + + YIF+AA+G WL+TV T I +FG ++L+ L G LSHQI Sbjct: 299 AMILIYIFSPKTDLNFYIFAAALGFTWLATVTPTASITGKLFGTRYLATLFGLTMLSHQI 358 Query: 353 GSFLGVWLGGYLFTREGSYNTVWMITIGLGLFATVMNLPVNE 394 G FLG ++GG + T+ G Y +W L A ++NLP+ E Sbjct: 359 GGFLGSYIGGIVITQFGDYGWMWYADALLAGTAALLNLPIRE 400 >AGl3235 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 433 Score = 111 bits (278), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 94/341 (27%), Positives = 157/341 (46%), Gaps = 22/341 (6%) Query: 32 GFWLQPISQAHGWTRETFSLAIALQNLMWGVFGPFAGMAADRYGTARVIVIGALLYMGGL 91 G +QP+ Q GW S A+A++ +++G+ GPFA + +G +V+ L MGG+ Sbjct: 42 GVMIQPLHQEFGWDIADISSAMAVRLVLFGLLGPFAAAFMNHFGIRQVVSTALALIMGGI 101 Query: 92 LWMALVDQPMLFAVGSGVLIGAALSCTAFGAISGIVGRSAPPEKRSLAFGISSAAGSFGQ 151 + + Q + GV+IG TA + V ++R L G+ +A+ + GQ Sbjct: 102 VASFFMTQVWQLLLLWGVVIGVGTGMTAL-VLGATVASRWFSKRRGLVIGLMTASNATGQ 160 Query: 152 FVMMPVEQQLISVTGWQQAFYWLSALVVAVMVPMAFRLR------------EPKLAHSGK 199 V +P+ L GW+ A A++ A M+ + +R E ++ K Sbjct: 161 LVFLPLLAALTEAYGWRTALTLSVAVIAAAMILVLLLMRDHPSDVGLPAYGETAVSKPPK 220 Query: 200 QEQSIWEA------TREAFAYRP-FQFLIAGYFVCGFQVV-FIGAHLPSYLKDKGLMDPN 251 Q+ ++ T ++ + P F L +FVCG I H S D G M Sbjct: 221 QDHNLLATLASPLVTLKSVSGNPVFWVLFGTFFVCGLSTNGLIQTHWISICGDFG-MAAV 279 Query: 252 IAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAPLSSWSVYIF 311 A LA+IG+F+ FG+ +AG L R+LL Y R +++ + S + +F Sbjct: 280 TAAGTLAVIGIFDFFGTIFAGWLSDRFDNRFLLFWFYGLRGLSLIYLSFSGFSFVELSVF 339 Query: 312 SAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQI 352 + GL W++TVP T + A FG + ++ G+VF HQ+ Sbjct: 340 AVFYGLDWVATVPPTVKLAAENFGREKAGLVFGWVFAGHQL 380