BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0357.p (323 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ytfF [GER] COG0697 Permeases of the drug/metabolite transporter ... 274 2e-73 ZytfF [GER] COG0697 Permeases of the drug/metabolite transporter... 272 6e-73 ECs5188 [GER] COG0697 Permeases of the drug/metabolite transport... 272 6e-73 STM4400 [GER] COG0697 Permeases of the drug/metabolite transport... 266 4e-71 RSc1428 [GER] COG0697 Permeases of the drug/metabolite transport... 138 2e-32 >ytfF [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 324 Score = 274 bits (701), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 150/317 (47%), Positives = 203/317 (64%), Gaps = 4/317 (1%) Query: 1 MFIGILCALCAGLMWGLVFVTPLLLGDYPGVVLSLGRYVAFGLIALAPAWFDRRRIGLLS 60 M G+L AL AGLMWGL+FV PL++ +YP ++ S+GRY+A GLIAL AW R R+ L+ Sbjct: 4 MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLIALPIAWLGRVRLRQLA 63 Query: 61 RQDWTVAFKLALVGNLIYYAMLATAIQLADAPLPTMLIGTLPIVISVCANWRPGHVSESV 120 R+DW A L ++GNLIYY LA+AIQ AP+ TM+IGTLP+VI V AN + Sbjct: 64 RRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLPVVIPVFANLLYSQRDGKL 123 Query: 121 AWSRLAPSLMILGLGLTLVNSSELERLRDTIGNARSTTDYALGCLIAVCAIAAWTWYPIV 180 AW +LAP+L+ +G+GL VN +EL AR T+ G ++A+ ++ W WY + Sbjct: 124 AWGKLAPALICIGIGLACVNIAELNHGLPDFDWARYTS----GIVLALVSVVCWAWYALR 179 Query: 181 NSRYLRTHTHINSVTWATAQGLATLPMALIGFALFGIYGVASGSDYAFPLGPRPGTFVVM 240 N+R+LR + + + WATAQ L TLP++LIG+ + + D++ P GPRP F+ + Sbjct: 180 NARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNTQTPDFSLPFGPRPLVFISL 239 Query: 241 MLVIGLSASWLGTLLWNKASQLLPTALVAQLIVFETLAALLYAFLLRGVAPDLRVLAGAV 300 M+ I + SW+G L WN ASQLLPT ++ LIVFETLA LLY FLLR P L L+G Sbjct: 240 MVAIAVLCSWVGALCWNVASQLLPTVILGPLIVFETLAGLLYTFLLRQQMPPLMTLSGIA 299 Query: 301 LLCIGVVYGVRTFSRRP 317 LL IGVV VR +P Sbjct: 300 LLVIGVVIAVRAKPEKP 316 >ZytfF [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 324 Score = 272 bits (696), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 149/317 (47%), Positives = 202/317 (63%), Gaps = 4/317 (1%) Query: 1 MFIGILCALCAGLMWGLVFVTPLLLGDYPGVVLSLGRYVAFGLIALAPAWFDRRRIGLLS 60 M G+L AL AGLMWGL+FV PL++ +YP ++ S+GRY+A GLIAL AW R R+ L+ Sbjct: 4 MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLIALPIAWLGRVRLRQLA 63 Query: 61 RQDWTVAFKLALVGNLIYYAMLATAIQLADAPLPTMLIGTLPIVISVCANWRPGHVSESV 120 R+DW A L ++GNLIYY LA+AIQ AP+ TM+IGTLP+VI V AN + Sbjct: 64 RRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLPVVIPVFANLLYSQRDGKL 123 Query: 121 AWSRLAPSLMILGLGLTLVNSSELERLRDTIGNARSTTDYALGCLIAVCAIAAWTWYPIV 180 AW +LAP+L+ +G+GL VN +EL AR T+ G ++A+ ++ W WY + Sbjct: 124 AWGKLAPALICIGIGLACVNIAELNHGLPNFDWARYTS----GIVLALVSVVCWAWYALR 179 Query: 181 NSRYLRTHTHINSVTWATAQGLATLPMALIGFALFGIYGVASGSDYAFPLGPRPGTFVVM 240 N+R+LR + + + WATAQ L TLP++LIG+ + + D++ P GPRP F+ + Sbjct: 180 NARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNTQTPDFSLPFGPRPLVFISL 239 Query: 241 MLVIGLSASWLGTLLWNKASQLLPTALVAQLIVFETLAALLYAFLLRGVAPDLRVLAGAV 300 M+ I + SW+G L WN ASQ LPT ++ LIVFETLA LLY FLLR P L L+G Sbjct: 240 MIAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGLLYTFLLRQQMPPLMTLSGIA 299 Query: 301 LLCIGVVYGVRTFSRRP 317 LL IGVV VR +P Sbjct: 300 LLVIGVVIAVRAKPEKP 316 >ECs5188 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ecs Escherichia coli O157:H7 Length = 324 Score = 272 bits (696), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 149/317 (47%), Positives = 202/317 (63%), Gaps = 4/317 (1%) Query: 1 MFIGILCALCAGLMWGLVFVTPLLLGDYPGVVLSLGRYVAFGLIALAPAWFDRRRIGLLS 60 M G+L AL AGLMWGL+FV PL++ +YP ++ S+GRY+A GLIAL AW R R+ L+ Sbjct: 4 MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLIALPIAWLGRVRLRQLA 63 Query: 61 RQDWTVAFKLALVGNLIYYAMLATAIQLADAPLPTMLIGTLPIVISVCANWRPGHVSESV 120 R+DW A L ++GNLIYY LA+AIQ AP+ TM+IGTLP+VI V AN + Sbjct: 64 RRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLPVVIPVFANLLYSQRDGKL 123 Query: 121 AWSRLAPSLMILGLGLTLVNSSELERLRDTIGNARSTTDYALGCLIAVCAIAAWTWYPIV 180 AW +LAP+L+ +G+GL VN +EL AR T+ G ++A+ ++ W WY + Sbjct: 124 AWGKLAPALICIGIGLACVNIAELNHGLPNFDWARYTS----GIVLALVSVVCWAWYALR 179 Query: 181 NSRYLRTHTHINSVTWATAQGLATLPMALIGFALFGIYGVASGSDYAFPLGPRPGTFVVM 240 N+R+LR + + + WATAQ L TLP++LIG+ + + D++ P GPRP F+ + Sbjct: 180 NARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNTQTPDFSLPFGPRPLVFISL 239 Query: 241 MLVIGLSASWLGTLLWNKASQLLPTALVAQLIVFETLAALLYAFLLRGVAPDLRVLAGAV 300 M+ I + SW+G L WN ASQ LPT ++ LIVFETLA LLY FLLR P L L+G Sbjct: 240 MIAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGLLYTFLLRQQMPPLMTLSGIA 299 Query: 301 LLCIGVVYGVRTFSRRP 317 LL IGVV VR +P Sbjct: 300 LLVIGVVIAVRAKPEKP 316 >STM4400 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 321 Score = 266 bits (681), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 146/319 (45%), Positives = 200/319 (62%), Gaps = 4/319 (1%) Query: 1 MFIGILCALCAGLMWGLVFVTPLLLGDYPGVVLSLGRYVAFGLIALAPAWFDRRRIGLLS 60 M G+L AL AGLMWGL+FV PL++ DYP ++ S+GRY+A GLIAL AW R R+ L+ Sbjct: 1 MISGVLYALLAGLMWGLIFVGPLIVPDYPALLQSMGRYLALGLIALPIAWLGRTRLRQLT 60 Query: 61 RQDWTVAFKLALVGNLIYYAMLATAIQLADAPLPTMLIGTLPIVISVCANWRPGHVSESV 120 R+DW+ A L L+GN+IYYA LA+AIQ AP+ TM+IGTLP+VI + AN + Sbjct: 61 RKDWSTALSLTLMGNVIYYACLASAIQRTGAPVSTMIIGTLPVVIPLFANVLYSQRDGRL 120 Query: 121 AWSRLAPSLMILGLGLTLVNSSELERLRDTIGNARSTTDYALGCLIAVCAIAAWTWYPIV 180 +W RLAP+L ++G GL VN +EL + + R Y G ++A+ ++A W WY + Sbjct: 121 SWRRLAPALALIGFGLLCVNIAELSQGLSDVSGWR----YGSGIVLALISVACWAWYALR 176 Query: 181 NSRYLRTHTHINSVTWATAQGLATLPMALIGFALFGIYGVASGSDYAFPLGPRPGTFVVM 240 N+R+LR + + + WATAQ L TLP++LIG+A ++ + P GP P F+ + Sbjct: 177 NARWLRENPDKHPMMWATAQALVTLPVSLIGYAAVCLWLSIQKPLFTLPFGPHPALFIGL 236 Query: 241 MLVIGLSASWLGTLLWNKASQLLPTALVAQLIVFETLAALLYAFLLRGVAPDLRVLAGAV 300 M+ I + SW+G L WN ASQ LPT ++ LIVFETLA LLY F+LR P L+G Sbjct: 237 MIAIAVLCSWVGALCWNIASQKLPTVILGPLIVFETLAGLLYTFILRQEIPPFLTLSGIA 296 Query: 301 LLCIGVVYGVRTFSRRPAV 319 LL GVV VR + V Sbjct: 297 LLVAGVVIAVRAKPEKATV 315 >RSc1428 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 138 bits (347), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 111/312 (35%), Positives = 159/312 (50%), Gaps = 8/312 (2%) Query: 1 MFIGILCALCAGLMWGLVFVTPLLLGDYPGVVLSLGRYVAFGLIALAPAWFDRRRIG-LL 59 M IG+LCAL AG MWG+VF+ P L + L+LGRY+A+G IA A RI L Sbjct: 1 MGIGVLCALLAGAMWGMVFIAPRALPAFSPWELALGRYLAYGAIAALAAAPILPRIARKL 60 Query: 60 SRQDWTVAFKLALVGNLIYYAMLATAIQLADAPLPTMLIGTLPIVISVCANWRPGHVSES 119 +R D + A GNL+YY +LA +QLA +++IG LPI ++V R H + Sbjct: 61 TRADCLALMRQACSGNLVYYVLLAFGVQLAGVAPVSLIIGVLPITVTVLG--RRDH--GA 116 Query: 120 VAWSRLAPSLMILGLGLTLVNSSELERLRDTIGNARSTTDYALGCLIAVCAIAAWTWYPI 179 V SRLA L+++ G+ +N G+A G A A+ +WTWY I Sbjct: 117 VPLSRLAWPLLVVAAGIACINIDLFSHDAVAAGDAHPIWSRIAGIACAAGALCSWTWYAI 176 Query: 180 VNSRYLRTHTHINSVTWATAQGLATLPMALIGFALFGIYGVASGSDYAFPLGPRPGTFVV 239 N+R+L+ + H +S W+ G++T ++ A + +A G TF Sbjct: 177 DNARHLQRNPHFSSNEWSALYGISTGALSAALTAAAVLAAGTG---WAEGGGRVWTTFWA 233 Query: 240 MMLVIGLSASWLGTLLWNKASQLLPTALVAQLIVFETLAALLYAFLLRGVAPDLRVLAGA 299 + + L AS +G LWN A++ LP L Q+IVFETL AL Y F+ P +A Sbjct: 234 VNAAVALGASLIGNNLWNIAARRLPLTLSGQMIVFETLFALAYGFVYDHRWPRPLEMAAI 293 Query: 300 VLLCIGVVYGVR 311 LL +GV + VR Sbjct: 294 ALLIVGVGWSVR 305