BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0326.p (377 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc01513 [P] COG3720 Putative heme degradation protein Sme Sinor... 254 2e-67 PA4709 [P] COG3720 Putative heme degradation protein Pae Pseudom... 248 2e-65 RSp0243 [P] COG3720 Putative heme degradation protein Rso Ralsto... 240 4e-63 mll1152 Non COG 219 1e-56 YPO0282 [P] COG3720 Putative heme degradation protein Ype Yersin... 217 3e-56 >SMc01513 [P] COG3720 Putative heme degradation protein Sme Sinorhizobium meliloti Length = 355 Score = 254 bits (649), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 134/341 (39%), Positives = 191/341 (56%), Gaps = 8/341 (2%) Query: 35 ALRVEQPKLQPRDAAQKLNVSEAELVATNVGKGATRLRDGGPAYKAVYDRLHELGQIKAI 94 A R E PKL+ RD A KL +SEA LVA G A R+ + +R+ ELG++ A+ Sbjct: 16 AYRAENPKLRERDIAAKLGISEAALVAAECGLTAVRIESSAGRF---LERVEELGEVLAL 72 Query: 95 TRNDNAVLERVGTVTQAKLNADGRVIPGTGFAGGPIDLRFGADQWRSAFAVVQPGREGKT 154 TRN++AV E+VG K ++ G+ IDLR W FAV + +G+ Sbjct: 73 TRNESAVHEKVGVYENIKQGHAAALVLGS-----EIDLRIFPGAWAHGFAVTKTDAKGEV 127 Query: 155 SRSLQFFDVHGNAVNKVYLDNEAGVAAFDKLVADFKAPEQLAYLSVDKAPAKVVTKPNVE 214 RSLQFFD G+AV+KV+L ++ +AA+DK+V D + +Q D + Sbjct: 128 RRSLQFFDKWGHAVHKVHLRPQSNLAAYDKMVEDLRLDDQSQDFIADAGAPATDDAVDAA 187 Query: 215 VDVKELRDTWNELSDVHEFPRLLKDLGITREQALDLIGKDAAYRISAQSVQTLLDSAARQ 274 VD ELRD W++L+D H+FP +L+ L I R +AL IG D A+R+ ++ ++ SAA Sbjct: 188 VDTAELRDRWSKLTDTHQFPGMLRKLNIGRRRALHAIGDDFAWRLDTACIEMMMRSAAET 247 Query: 275 GQPIMVFVSNPGMTQIFSGKITKVKATEEWYNVLDPDFNLHLRQAGIDRGWVVKRPAKDG 334 PIM FV N G+ QI SG + K+ W NV+D F+LHLR I W V++P DG Sbjct: 248 ALPIMCFVGNGGVIQIHSGPVVKIGTMGPWLNVMDETFHLHLRTDHIAELWAVRKPTADG 307 Query: 335 VITSVEFYDAKGEQVVNFFSRRDRNKEETTTWRNIVANLTK 375 +TS+E DAKGE ++ FF +R E WR++V L + Sbjct: 308 HVTSLEGLDAKGEMIIQFFGKRKEGSSERAEWRSLVEELPR 348 >PA4709 [P] COG3720 Putative heme degradation protein Pae Pseudomonas aeruginosa Length = 354 Score = 248 bits (632), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 143/358 (39%), Positives = 201/358 (56%), Gaps = 14/358 (3%) Query: 22 STTPN-----SNLAERWSALRVEQPKLQPRDAAQKLNVSEAELVATNVGKGATRLRDGGP 76 S+TP+ + L W LR E+P+L+ RDAA L VSE ELVA+ VG A RLR P Sbjct: 2 SSTPSLSHSPAELYRAWQDLRAERPQLRARDAAALLQVSEGELVASRVGIDAVRLR---P 58 Query: 77 AYKAVYDRLHELGQIKAITRNDNAVLERVGTVTQAKLNADGRVIPGTGFAGGP-IDLRFG 135 + A+ L ELG I A+TRN++ V ER G + ++A+G++ G P IDLR Sbjct: 59 DWAALLPALGELGPIMALTRNEHCVHERKGPYREVTVSANGQM----GLVVSPDIDLRLF 114 Query: 136 ADQWRSAFAVVQPGREGKTSRSLQFFDVHGNAVNKVYLDNEAGVAAFDKLVADFKAPEQL 195 W + FA+ + G T RS+Q FD G AV+KV+L + V A++ LV +A EQ Sbjct: 115 LGGWNAVFAIAEETARG-TQRSIQVFDQQGVAVHKVFLAEASDVRAWEPLVERLRAAEQD 173 Query: 196 AYLSVDKAPAKVVTKPNVEVDVKELRDTWNELSDVHEFPRLLKDLGITREQALDLIGKDA 255 A L++ + A + ++D LR+ W L D H F LLK G R QAL L G + Sbjct: 174 AVLALHEPRAPAAALVDAQIDAAALREGWAALKDTHHFHALLKKHGAQRTQALRLAGGEW 233 Query: 256 AYRISAQSVQTLLDSAARQGQPIMVFVSNPGMTQIFSGKITKVKATEEWYNVLDPDFNLH 315 A R+ + L ++AA G PIMVFV N QI +G + +K ++W+NVLDP+FNLH Sbjct: 234 AERLDNGDLAKLFEAAAESGLPIMVFVGNAHCIQIHTGPVCNLKWLDDWFNVLDPEFNLH 293 Query: 316 LRQAGIDRGWVVKRPAKDGVITSVEFYDAKGEQVVNFFSRRDRNKEETTTWRNIVANL 373 L+ GI W V++P+ DG++TS E +DA GE +V F R + E WR + + Sbjct: 294 LKTTGIAELWRVRKPSTDGIVTSWEAFDADGELIVQLFGARKPGEPERDDWRELAESF 351 >RSp0243 [P] COG3720 Putative heme degradation protein Rso Ralstonia solanacearum Length = 380 Score = 240 bits (613), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 144/349 (41%), Positives = 198/349 (56%), Gaps = 10/349 (2%) Query: 27 SNLAERWSALRVEQPKLQPRDAAQKLNVSEAELVATNVGKGATRLRDGGPA-YKAVYDRL 85 + L ER AL E+ L+ RDAA +L VSE ELVA VG TRLR G + ++++L Sbjct: 22 ARLRERHRALLAER-SLRQRDAAAELGVSEGELVAARVGADVTRLRAGEDGHFIGLFEQL 80 Query: 86 HELGQIKAITRNDNAVLERVGTVTQAKLNADGRVIPGTGFA-GGPIDLRFGADQWRSAFA 144 LG++ A+TRN AV E+ GT T L+ G V G A G IDLR W A+A Sbjct: 81 GALGRVMALTRNAAAVHEKDGTFT--SLSHTGLV----GLALGAEIDLRMFYAHWAHAYA 134 Query: 145 VVQPGREGKTSRSLQFFDVHGNAVNKVYLDNEAGVAAFDKLVADFKAPEQLAYLSVDKAP 204 V G T RSLQF+D G AV+KVYL + AA D+LVA ++A +Q ++ P Sbjct: 135 VTDTSPRG-TLRSLQFYDACGEAVHKVYLREHSDHAACDRLVAQWRADDQAPGDAMQARP 193 Query: 205 AKVVTKPNVEVDVKELRDTWNELSDVHEFPRLLKDLGITREQALDLIGKDAAYRISAQSV 264 A +P+ +DV L W ++D H+F LLK + R QAL L ++ ++ Sbjct: 194 APDAPRPDSAIDVPALLSAWEAMTDTHQFFGLLKAHEVARTQALRLAEGRFTLAVAPTAL 253 Query: 265 QTLLDSAARQGQPIMVFVSNPGMTQIFSGKITKVKATEEWYNVLDPDFNLHLRQAGIDRG 324 +L+ AA G PIMVFV N GM QI +G +T V+ + W NVLDP F+LH+R IDR Sbjct: 254 SAVLEEAAATGLPIMVFVGNRGMVQIHTGPVTTVRRLDGWVNVLDPGFSLHVRGDLIDRA 313 Query: 325 WVVKRPAKDGVITSVEFYDAKGEQVVNFFSRRDRNKEETTTWRNIVANL 373 WVV +P DGV+T++E +DA+GE + F R + E WR+++ L Sbjct: 314 WVVCKPTSDGVVTALELFDAQGETIAMLFGARKPGEPERPAWRDLMRRL 362 >mll1152 Non COG Length = 353 Score = 219 bits (557), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 125/341 (36%), Positives = 185/341 (54%), Gaps = 12/341 (3%) Query: 37 RVEQPKLQPRDAAQKLNVSEAELVATNVGKGATRLRDGGPAYKAVYDRLHELGQIKAITR 96 R E PK + RD A +L +SEAELVA + G G R+ P + L +G++ A+TR Sbjct: 16 RTENPKTRERDLAAQLGISEAELVAAHCGDGVVRIE---PRVNDLLTGLEAVGEVMALTR 72 Query: 97 NDNAVLERVGTVTQAKLNADGRVIPGTGFAGGPIDLRFGADQWRSAFAVVQPGREG-KTS 155 N++AV E++G + ++ G IDLR W FAV + R+G + Sbjct: 73 NESAVHEKIGVYDKVVTGNHNAMVLGEN-----IDLRIFPKVWAHGFAVEK--RDGDEIR 125 Query: 156 RSLQFFDVHGNAVNKVYLDNEAGVAAFDKLVADFKAPEQLAYLSVDKAPAKVVTKPN-VE 214 RSLQFFD G AV+KV+L + + A+ KLVA ++ Q + + + + ++ Sbjct: 126 RSLQFFDATGKAVHKVHLRPASSLYAYQKLVASLESSNQEPTVDISGSISDDRSEAGATA 185 Query: 215 VDVKELRDTWNELSDVHEFPRLLKDLGITREQALDLIGKDAAYRISAQSVQTLLDSAARQ 274 V +LRD W+ L+DVH+F +LK L ++R QA+ ++G D A+ + +V + AA Sbjct: 186 VSPDDLRDRWSRLTDVHQFFGMLKTLKLSRRQAVRMVGTDYAWLLDNDAVGAMFHHAAEG 245 Query: 275 GQPIMVFVSNPGMTQIFSGKITKVKATEEWYNVLDPDFNLHLRQAGIDRGWVVKRPAKDG 334 PIM FV N G QI SG + +K W NVLD F+LHLR I W V++P KDG Sbjct: 246 EMPIMCFVGNRGCIQIHSGPVRSIKPMGPWINVLDETFHLHLRTDHIQEVWAVRKPTKDG 305 Query: 335 VITSVEFYDAKGEQVVNFFSRRDRNKEETTTWRNIVANLTK 375 +TS+E Y A GE ++ FF +R + E WR + NL + Sbjct: 306 HVTSLEVYAADGEMIIQFFGKRHEGESERDDWRFLAENLPR 346 >YPO0282 [P] COG3720 Putative heme degradation protein Ype Yersinia pestis Length = 345 Score = 217 bits (553), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 125/352 (35%), Positives = 186/352 (52%), Gaps = 19/352 (5%) Query: 26 NSNLAERWSALRVEQPKLQPRDAAQKLNVSEAELVATNVGKGATRLRDGGPAYKAVYDRL 85 N++L +++ + E P RD A + +SEAEL + VG A RL+ +A+ L Sbjct: 2 NASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDA---RALLAAL 58 Query: 86 HELGQIKAITRNDNAVLERVGTVTQAKLNADGRVIPGTGFAGGPIDLRFGADQWRSAFAV 145 +G++KAITRN AV E+VG LN +I +DLR +QW SAF + Sbjct: 59 ESVGEVKAITRNTYAVHEQVGRYENQHLNGHAGLI----LNPRALDLRLFLNQWASAFTL 114 Query: 146 VQPGREGKTSRSLQFFDVHGNAVNKVYLDNEAGVAAFDKLVADFKAPE----QLAYLSVD 201 + R G S+QFFD G+A++KVY+ + ++A++ L+A F PE QL LS Sbjct: 115 TEETRHG-VRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIPENPALQLEPLSTP 173 Query: 202 KAPAKVVTKPNVEVDVKELRDTWNELSDVHEFPRLLKDLGITREQALDLIGKDAAYRISA 261 +A V+ + W ++DVH+F +LLK +TR+QA +G D AY++ Sbjct: 174 EAVEPTADDATVDSE-------WRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDN 226 Query: 262 QSVQTLLDSAARQGQPIMVFVSNPGMTQIFSGKITKVKATEEWYNVLDPDFNLHLRQAGI 321 S+ LL A + IM+FV N G QIF+G I KV EW NV + F LHL + I Sbjct: 227 NSLTQLLHIAQQDQNEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAI 286 Query: 322 DRGWVVKRPAKDGVITSVEFYDAKGEQVVNFFSRRDRNKEETTTWRNIVANL 373 W+ ++P KDG +TS+E + A G Q+ + +R + E WR +A L Sbjct: 287 AESWITRKPTKDGFVTSLELFAADGTQLAQLYGQRTEGQPEQNQWREQIARL 338