BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0140.p (412 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0412 [GEPR] COG0477 Permeases of the major facilitator superf... 439 e-123 BMEI1292 [GEPR] COG0477 Permeases of the major facilitator super... 434 e-121 fsr [GEPR] COG0477 Permeases of the major facilitator superfamil... 428 e-119 Zfsr [GEPR] COG0477 Permeases of the major facilitator superfami... 426 e-119 ECs0532 [GEPR] COG0477 Permeases of the major facilitator superf... 426 e-119 >RSp0412 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 411 Score = 439 bits (1130), Expect = e-123, Method: Compositional matrix adjust. Identities = 242/382 (63%), Positives = 303/382 (79%), Gaps = 3/382 (0%) Query: 34 IVLAVGFAHLINDLIQALLPSIYPMLKQNYGLSFTQVGLITLTFQVTASLIQPWIGMYTD 93 ++ A+ FAH +ND++Q+L+ +IYP+LK N+ L FTQ+GLITLT+Q+TASL+QP +G+YTD Sbjct: 24 VIGAISFAHFLNDMMQSLILAIYPLLKGNFHLDFTQIGLITLTYQITASLLQPMVGLYTD 83 Query: 94 KHPKPLLLPCGALFTLLGIVLLSMAGSFGWFLLAAGLIGVGSSTFHPEASRIARMASGGR 153 +HPKP LP G FTL+G++L+S+A +FG LLAA L+G GSS FHPE+SR+ARMASGGR Sbjct: 84 RHPKPYSLPVGMGFTLVGLLLMSVAPNFGTLLLAAALVGTGSSIFHPESSRVARMASGGR 143 Query: 154 FGFAQSTFQVGGNAGSALGPLLAAAIVVPFGQPNIAWFCIFAVVAIVVLSRVSNWYRHHL 213 G AQS FQVGGN GSA+GPLLAAA+++P+GQ ++AWF I A+VA+VVL V WYR Sbjct: 144 HGLAQSLFQVGGNVGSAMGPLLAAAVIMPYGQHSLAWFSIAALVAMVVLYHVGGWYRRER 203 Query: 214 AAGA---KKARATVHHHLSSGTVKKALLVLALLVFSKYFYMAGFTSYFTFYLIDRFHLTV 270 AAG ARA L +G V KA+L+L +L+FSKYFY+A SY+TFYLI +FHL+ Sbjct: 204 AAGQGRKAGARAHAAARLPAGKVVKAMLLLVVLLFSKYFYLASLNSYYTFYLISKFHLSA 263 Query: 271 GDSQILLFLFLGAVAAGTFFGGPIGDKIGRKRVIWFSILGAAPFALLLPHANLFWTGVLC 330 SQ+ LFLFL +VAAGT GGPIGD+ GRK VIW SILG APF LLLPHANLFWT VL Sbjct: 264 QASQLFLFLFLFSVAAGTIAGGPIGDRFGRKVVIWVSILGVAPFTLLLPHANLFWTAVLT 323 Query: 331 VFVGFILASAFSAIVVYAQELVPGKVGLISGVFFGLMFGFGGIGAALLGHLADLYGIANV 390 V +G +LASAFSAI+VYAQEL+PG+VG++SG+FFG FG GGIGAA+LG LAD GI +V Sbjct: 324 VVIGLVLASAFSAILVYAQELIPGQVGMVSGLFFGFAFGLGGIGAAVLGRLADATGIDHV 383 Query: 391 YLLCSLLPLAGVLTVFLPDLKE 412 Y LCS LPL G+LTVFLPD++ Sbjct: 384 YHLCSFLPLIGLLTVFLPDIER 405 >BMEI1292 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 403 Score = 434 bits (1115), Expect = e-121, Method: Compositional matrix adjust. Identities = 223/397 (56%), Positives = 288/397 (72%), Gaps = 2/397 (0%) Query: 16 AASAPAATQAGSSPLVLRIVLAVGFAHLINDLIQALLPSIYPMLKQNYGLSFTQVGLITL 75 AA P+ + A ++ VL I+LA H +ND++Q+LLP+IYPMLK+NY LSF Q+GL+T Sbjct: 5 AAQQPSNSSADNT--VLTIILATSLGHFLNDMMQSLLPAIYPMLKENYSLSFWQIGLLTF 62 Query: 76 TFQVTASLIQPWIGMYTDKHPKPLLLPCGALFTLLGIVLLSMAGSFGWFLLAAGLIGVGS 135 TFQ+TAS++QP +G+YTD+ P P L G TL+G+V L+ A + + LL A +G GS Sbjct: 63 TFQMTASILQPLVGIYTDRKPMPYSLTFGMGCTLIGLVFLATAHHYSFLLLGAACVGFGS 122 Query: 136 STFHPEASRIARMASGGRFGFAQSTFQVGGNAGSALGPLLAAAIVVPFGQPNIAWFCIFA 195 S FHPEA+R+AR+ASGGR GFAQS FQVGGN GS++GPLLAA IV+PFGQ +++WF + A Sbjct: 123 SVFHPEAARVARLASGGRHGFAQSLFQVGGNFGSSIGPLLAAFIVLPFGQISVSWFSVAA 182 Query: 196 VVAIVVLSRVSNWYRHHLAAGAKKARATVHHHLSSGTVKKALLVLALLVFSKYFYMAGFT 255 ++ + VL V NWY + A A K + L V ++ VLALLVF+KY YMA T Sbjct: 183 LIGMFVLWYVGNWYNRYRLANANKPKPDKTLPLPRNRVIASVAVLALLVFTKYIYMASLT 242 Query: 256 SYFTFYLIDRFHLTVGDSQILLFLFLGAVAAGTFFGGPIGDKIGRKRVIWFSILGAAPFA 315 SY+TFY I F ++V SQ+LLFLFLGAVAAGT GGPIGDKIG ++VIW SILG PF Sbjct: 243 SYYTFYTISHFGVSVQTSQLLLFLFLGAVAAGTIIGGPIGDKIGARKVIWASILGVLPFT 302 Query: 316 LLLPHANLFWTGVLCVFVGFILASAFSAIVVYAQELVPGKVGLISGVFFGLMFGFGGIGA 375 L LP+ANL T VL + +G ILASAF AI+V+AQEL+PG+VG++SG+FFG FG GI A Sbjct: 303 LALPYANLEMTAVLTIIIGLILASAFPAIIVFAQELLPGRVGMLSGLFFGFAFGMAGIAA 362 Query: 376 ALLGHLADLYGIANVYLLCSLLPLAGVLTVFLPDLKE 412 A+LG +AD GI VY +CS LP G+LT+FLP L+ Sbjct: 363 AVLGIVADQKGIEFVYRICSYLPFLGLLTIFLPKLER 399 >fsr [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 406 Score = 428 bits (1100), Expect = e-119, Method: Compositional matrix adjust. Identities = 227/402 (56%), Positives = 303/402 (75%) Query: 11 LSDAPAASAPAATQAGSSPLVLRIVLAVGFAHLINDLIQALLPSIYPMLKQNYGLSFTQV 70 +S+ P A AA + I+ A+ +HL+ND+IQ+L+ +IYP+L+ + L+F Q+ Sbjct: 3 MSEQPQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQSEFSLTFMQI 62 Query: 71 GLITLTFQVTASLIQPWIGMYTDKHPKPLLLPCGALFTLLGIVLLSMAGSFGWFLLAAGL 130 G+ITLTFQ+ +SL+QP +G +TDK+P P LP G FTL G+VLL++AGSFG LLAA L Sbjct: 63 GMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSFGAVLLAAAL 122 Query: 131 IGVGSSTFHPEASRIARMASGGRFGFAQSTFQVGGNAGSALGPLLAAAIVVPFGQPNIAW 190 +G GSS FHPE+SR+ARMASGGR G AQS FQVGGN GS+LGPLLAA I+ P+G+ N+AW Sbjct: 123 VGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNVAW 182 Query: 191 FCIFAVVAIVVLSRVSNWYRHHLAAGAKKARATVHHHLSSGTVKKALLVLALLVFSKYFY 250 F + A++AIVVL+++S WY K +AT+ + L V A+ +L +L+FSKYFY Sbjct: 183 FVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILLILIFSKYFY 242 Query: 251 MAGFTSYFTFYLIDRFHLTVGDSQILLFLFLGAVAAGTFFGGPIGDKIGRKRVIWFSILG 310 MA +SY+TFYL+ +F L++ ++Q+ LF FL AVAAGT GGP+GDKIGRK VIW SILG Sbjct: 243 MASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILG 302 Query: 311 AAPFALLLPHANLFWTGVLCVFVGFILASAFSAIVVYAQELVPGKVGLISGVFFGLMFGF 370 APF L+LP+A+L WTGVL V +GFILASAFSAI+VYAQEL+PG++G++SG+FFG FG Sbjct: 303 VAPFTLILPYASLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGM 362 Query: 371 GGIGAALLGHLADLYGIANVYLLCSLLPLAGVLTVFLPDLKE 412 GG+GAA+LG +AD I VY +C+ LPL G+LT+FLPD + Sbjct: 363 GGLGAAVLGLIADHTSIELVYKICAFLPLLGMLTIFLPDNRH 404 >Zfsr [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 406 Score = 426 bits (1094), Expect = e-119, Method: Compositional matrix adjust. Identities = 227/398 (57%), Positives = 302/398 (75%), Gaps = 2/398 (0%) Query: 15 PAASAPAATQAGSSPLVLRIVLAVGFAHLINDLIQALLPSIYPMLKQNYGLSFTQVGLIT 74 P A A A+T + I+ A+ +HL+ND+IQ+L+ +IYP+L+ + L+F Q+G+IT Sbjct: 9 PVAGAAASTTKARTSF--GILGAISLSHLLNDMIQSLILAIYPLLQSEFSLTFMQIGMIT 66 Query: 75 LTFQVTASLIQPWIGMYTDKHPKPLLLPCGALFTLLGIVLLSMAGSFGWFLLAAGLIGVG 134 LTFQ+ +SL+QP +G +TDK+P P LP G FTL G+VLL++AGSFG LLAA L+G G Sbjct: 67 LTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSFGAVLLAAALVGTG 126 Query: 135 SSTFHPEASRIARMASGGRFGFAQSTFQVGGNAGSALGPLLAAAIVVPFGQPNIAWFCIF 194 SS FHPE+SR+ARMASGGR G AQS FQVGGN GS+LGPLLAA I+ P+G+ N+AWF + Sbjct: 127 SSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNVAWFVLA 186 Query: 195 AVVAIVVLSRVSNWYRHHLAAGAKKARATVHHHLSSGTVKKALLVLALLVFSKYFYMAGF 254 A++AIVVL+++S WY K +AT+ + L V A+ +L +L+FSKYFYMA Sbjct: 187 ALLAIVVLAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILLILIFSKYFYMASI 246 Query: 255 TSYFTFYLIDRFHLTVGDSQILLFLFLGAVAAGTFFGGPIGDKIGRKRVIWFSILGAAPF 314 +SY+TFYL+ +F L++ ++Q+ LF FL AVAAGT GGP+GDKIGRK VIW SILG APF Sbjct: 247 SSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPF 306 Query: 315 ALLLPHANLFWTGVLCVFVGFILASAFSAIVVYAQELVPGKVGLISGVFFGLMFGFGGIG 374 L+LP+A+L WTGVL V +GFILASAFSAI+VYAQEL+PG++G++SG+FFG FG GG+G Sbjct: 307 TLILPYASLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLG 366 Query: 375 AALLGHLADLYGIANVYLLCSLLPLAGVLTVFLPDLKE 412 AA+LG +AD I VY +C+ LPL G+LT+FLPD + Sbjct: 367 AAVLGLIADHTSIELVYKICAFLPLLGMLTIFLPDNRH 404 >ECs0532 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 406 Score = 426 bits (1094), Expect = e-119, Method: Compositional matrix adjust. Identities = 227/398 (57%), Positives = 302/398 (75%), Gaps = 2/398 (0%) Query: 15 PAASAPAATQAGSSPLVLRIVLAVGFAHLINDLIQALLPSIYPMLKQNYGLSFTQVGLIT 74 P A A A+T + I+ A+ +HL+ND+IQ+L+ +IYP+L+ + L+F Q+G+IT Sbjct: 9 PVAGAAASTTKARTSF--GILGAISLSHLLNDMIQSLILAIYPLLQSEFSLTFMQIGMIT 66 Query: 75 LTFQVTASLIQPWIGMYTDKHPKPLLLPCGALFTLLGIVLLSMAGSFGWFLLAAGLIGVG 134 LTFQ+ +SL+QP +G +TDK+P P LP G FTL G+VLL++AGSFG LLAA L+G G Sbjct: 67 LTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSFGAVLLAAALVGTG 126 Query: 135 SSTFHPEASRIARMASGGRFGFAQSTFQVGGNAGSALGPLLAAAIVVPFGQPNIAWFCIF 194 SS FHPE+SR+ARMASGGR G AQS FQVGGN GS+LGPLLAA I+ P+G+ N+AWF + Sbjct: 127 SSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIAPYGKGNVAWFVLA 186 Query: 195 AVVAIVVLSRVSNWYRHHLAAGAKKARATVHHHLSSGTVKKALLVLALLVFSKYFYMAGF 254 A++AIVVL+++S WY K +AT+ + L V A+ +L +L+FSKYFYMA Sbjct: 187 ALLAIVVLAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILLILIFSKYFYMASI 246 Query: 255 TSYFTFYLIDRFHLTVGDSQILLFLFLGAVAAGTFFGGPIGDKIGRKRVIWFSILGAAPF 314 +SY+TFYL+ +F L++ ++Q+ LF FL AVAAGT GGP+GDKIGRK VIW SILG APF Sbjct: 247 SSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPF 306 Query: 315 ALLLPHANLFWTGVLCVFVGFILASAFSAIVVYAQELVPGKVGLISGVFFGLMFGFGGIG 374 L+LP+A+L WTGVL V +GFILASAFSAI+VYAQEL+PG++G++SG+FFG FG GG+G Sbjct: 307 TLILPYASLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLG 366 Query: 375 AALLGHLADLYGIANVYLLCSLLPLAGVLTVFLPDLKE 412 AA+LG +AD I VY +C+ LPL G+LT+FLPD + Sbjct: 367 AAVLGLIADHTSIELVYKICAFLPLLGMLTIFLPDNRH 404