BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0125.p (439 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 416 e-116 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 409 e-114 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 407 e-113 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 358 2e-98 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 341 2e-93 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 416 bits (1069), Expect = e-116, Method: Compositional matrix adjust. Identities = 216/428 (50%), Positives = 290/428 (67%), Gaps = 2/428 (0%) Query: 7 PATAQDIQESNLYRRITLRFVPLLVICFVFAYLDRVNISFAKLQMQQDLGFSDAVYGLGA 66 P +A +E+ YR+++ R +P L++C+V AYLDRVN+ FAKLQM DL FS+ VYGLGA Sbjct: 17 PQSASGFEEAT-YRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGA 75 Query: 67 SIFFVGYFLFEIPSNMILHKVGPKRWIARIMVTWGIASAAMMFVTNETGFYILRFLIGSL 126 IFF+GYFLFE+PSN+ILH+VG + WIARIM++WG+ SAAMMFVT FY++RFL+G Sbjct: 76 GIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLA 135 Query: 127 EAGFVPGALYFFTNWFPSQRRGRINSLFMAAIALCGMIGGPISGGIMKFTHGVSSLHGWQ 186 EAGF PG + + T W+P++RRGR + FM A+AL G+IGGPISG +K GV L GWQ Sbjct: 136 EAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQ 195 Query: 187 WLFLLEGIPSIVLGVICWIVIDNKIEDARWLKDDEKKLLLARLAAEPKSEAVHSFRDALK 246 W+FL+EGIPS+V+G+ +DN+I ARWL D+EK LL +AAE + + Sbjct: 196 WMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQKEDAPIAAIMA 255 Query: 247 QPSTITMSLIYLVLASGIYGLVFWMPQLIKTAGTDDTFIIGLITVIPYLCAAIGMILIGR 306 P MSLIY G+YG+ FW+P LIK G D +GL+T IPY A + M+L+ R Sbjct: 256 SPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVAR 315 Query: 307 SSDRTGERRWHLAGCALAGAVGYAVSAYFGSNTLVLVVGLSFAATGIIAGIGLFWILPPR 366 S+DRT ERRWH+A ALAGA+G +SA + +NT + + L+ GI+ + LFW LP Sbjct: 316 SADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTA 375 Query: 367 VLTGAAAAGGIALINSVGQLGGIITPYMVGKIRDITGSASLGLYVVALECLVGAALLLWA 426 L G AA GIALINS+G L G ++PY VG ++D T S G+Y++A ++GA L L + Sbjct: 376 FLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGALLTL-S 434 Query: 427 LPKRIYFR 434 +P R R Sbjct: 435 VPARTVNR 442 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 409 bits (1051), Expect = e-114, Method: Compositional matrix adjust. Identities = 211/417 (50%), Positives = 287/417 (68%), Gaps = 2/417 (0%) Query: 9 TAQDIQESNLYRRITLRFVPLLVICFVFAYLDRVNISFAKLQMQQDLGFSDAVYGLGASI 68 T+ ++ E+ YR++ R +PLL+IC++ AYLDRVN+ FAKLQM ++LGFS+A+YGLGA + Sbjct: 27 TSPEVVENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGL 86 Query: 69 FFVGYFLFEIPSNMILHKVGPKRWIARIMVTWGIASAAMMFVTNETGFYILRFLIGSLEA 128 FF+GYF FEIPSN++LHK+G + WIARIM+TWG+ SA FV E FYILRFL+G+ EA Sbjct: 87 FFIGYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEA 146 Query: 129 GFVPGALYFFTNWFPSQRRGRINSLFMAAIALCGMIGGPISGGIMKFTHGVSSLHGWQWL 188 GF PG + + T WFPS RRG + +LF A G+ G P+SG IM H + GWQW+ Sbjct: 147 GFYPGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWM 206 Query: 189 FLLEGIPSIVLGVICWIVIDNKIEDARWLKDDEKKLLLARLAAEPKSEAV-HSFRDALKQ 247 F+LE IP++VLGV+ + +DN ++ A+WL ++EK ++ + A+ K +A HS +K Sbjct: 207 FVLEAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASHSLMSLVKN 266 Query: 248 PSTITMSLIYLVLASGIYGLVFWMPQLIKTAGTDDTFIIGLITVIPYLCAAIGMILIGRS 307 P M LIY G +GL WMP LI+ +G IGL+ IP++CA I M++ RS Sbjct: 267 PMLWVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRS 326 Query: 308 SDRTGERRWHLAGCALAGAVGYAVSAYFGSNTLVLVVGLSFAATGIIAGIGLFWILPPRV 367 +D ERRWHL AL GAVG+ V+A +NT V ++ LS AA G++A LFW LP + Sbjct: 327 ADHYRERRWHLVVPALLGAVGFVVAAS-ATNTTVSIIFLSMAAAGVLACAPLFWSLPTAI 385 Query: 368 LTGAAAAGGIALINSVGQLGGIITPYMVGKIRDITGSASLGLYVVALECLVGAALLL 424 L+GAAAA GIALINSV L G I+PYMVG IRD T S+ LG+YV+A ++GAA++L Sbjct: 386 LSGAAAAAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLILGAAIVL 442 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 407 bits (1045), Expect = e-113, Method: Compositional matrix adjust. Identities = 204/415 (49%), Positives = 276/415 (66%) Query: 10 AQDIQESNLYRRITLRFVPLLVICFVFAYLDRVNISFAKLQMQQDLGFSDAVYGLGASIF 69 Q +E+N YR+ +PLL++C+V YLDRVN+ FAKLQM DL FSD VYGLGA +F Sbjct: 13 TQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMF 72 Query: 70 FVGYFLFEIPSNMILHKVGPKRWIARIMVTWGIASAAMMFVTNETGFYILRFLIGSLEAG 129 F+GYF EIPSN+ILH+VG + WIARIM+TWGI SA M FVT FY++RFL+G EAG Sbjct: 73 FIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAG 132 Query: 130 FVPGALYFFTNWFPSQRRGRINSLFMAAIALCGMIGGPISGGIMKFTHGVSSLHGWQWLF 189 F PG + + + WFPS RRGR+ LF+ ++ L G+IG P+SG IM++ +G GWQW+F Sbjct: 133 FFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMF 192 Query: 190 LLEGIPSIVLGVICWIVIDNKIEDARWLKDDEKKLLLARLAAEPKSEAVHSFRDALKQPS 249 +LEGIPS+++G++ + ++I A WL D EK +L + E A RDA QP Sbjct: 193 ILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYAHSRLRDAFLQPR 252 Query: 250 TITMSLIYLVLASGIYGLVFWMPQLIKTAGTDDTFIIGLITVIPYLCAAIGMILIGRSSD 309 ++LIY L SG Y + FW+P LI+ +G D IG +T IP AA+ MI++ RS+D Sbjct: 253 VWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSAD 312 Query: 310 RTGERRWHLAGCALAGAVGYAVSAYFGSNTLVLVVGLSFAATGIIAGIGLFWILPPRVLT 369 R ERRWHLA A+ GAVG +S YF N +V +V L+ A G ++ I LFW LP L Sbjct: 313 RLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLG 372 Query: 370 GAAAAGGIALINSVGQLGGIITPYMVGKIRDITGSASLGLYVVALECLVGAALLL 424 G+AAA GIA INS G LGG + PYM+G ++D+T S + G+ +++ +GAAL+ Sbjct: 373 GSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLFIGAALVF 427 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 358 bits (918), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 188/409 (45%), Positives = 255/409 (62%), Gaps = 3/409 (0%) Query: 1 MAAVPYPATAQDIQES-NLYRRITLRFVPLLVICFVFAYLDRVNISFAKLQMQQDLGFSD 59 MAA PA A + S ++Y + R +P L C++FAYLDR+NI FAKLQMQ DL SD Sbjct: 1 MAANAIPAQAHSGERSTSVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSD 60 Query: 60 AVYGLGASIFFVGYFLFEIPSNMILHKVGPKRWIARIMVTWGIASAAMMFVTNETGFYIL 119 A YGLGA IFF GY LFE+PSN++L K+G +R ++RI++ WGI SA+M+FVT+ FY L Sbjct: 61 AAYGLGAGIFFFGYMLFEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYAL 120 Query: 120 RFLIGSLEAGFVPGALYFFTNWFPSQRRGRINSLFMAAIALCGMIGGPISGGIMKFTHGV 179 RFL+G EAGF PG +Y+ T W+P +R R ++ + A L G+IGGP S IM G Sbjct: 121 RFLLGVFEAGFAPGMIYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGA 180 Query: 180 SSLHGWQWLFLLEGIPSIVLGVICWIVIDNKIEDARWLKDDEKKLLLARLAAEPKSEAVH 239 L GWQW+FL EGIPSI+LG+ + + +K DARWL D +K ++ +A +A Sbjct: 181 GGLAGWQWMFLAEGIPSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARAAPGQA-S 239 Query: 240 SFRDALKQPSTITMSLIYLVLASGIYGLVFWMPQLIKTAGTDDTFIIGLITVIPYLCAAI 299 SF AL +P ++ Y L G+Y + FW+P ++K+AG D F IGL + IP L + Sbjct: 240 SFGKALTEPKLYVLAAAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIV 299 Query: 300 GMILIGRSSDRTGERRWHLAGCALAGAVGYAVSAYFGSNTLVLVVGLSFAATGIIAGIGL 359 M +GR SDR GER H A A+ GA A +AY S L + ++ A+ I A + Sbjct: 300 AMYALGRRSDRRGERHLHSAITAVLGAGLLAWAAYATSFPAAL-ISITLASAAIFASYSV 358 Query: 360 FWILPPRVLTGAAAAGGIALINSVGQLGGIITPYMVGKIRDITGSASLG 408 FW +P + L G AAAGGIALINS+G GG +P ++G ++ TGS G Sbjct: 359 FWAIPQQHLKGTAAAGGIALINSIGLFGGFFSPTLIGWTKEATGSLQAG 407 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 341 bits (874), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 189/423 (44%), Positives = 266/423 (62%), Gaps = 6/423 (1%) Query: 8 ATAQDIQESNL------YRRITLRFVPLLVICFVFAYLDRVNISFAKLQMQQDLGFSDAV 61 +TA + + L + R+T R +PLL++C+VFA+LDR+NI FAKLQM DL FSD V Sbjct: 2 STASTLNSTTLPLSDSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTV 61 Query: 62 YGLGASIFFVGYFLFEIPSNMILHKVGPKRWIARIMVTWGIASAAMMFVTNETGFYILRF 121 YGLGA +FF+ Y LF +PSN++L ++GP+RWIA +M+ WG S AM+ V GFY+LRF Sbjct: 62 YGLGAGLFFIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRF 121 Query: 122 LIGSLEAGFVPGALYFFTNWFPSQRRGRINSLFMAAIALCGMIGGPISGGIMKFTHGVSS 181 L+G EAGF PG L + WFP++RRG+I +LF A+ + G+IGGP+SG I++ H Sbjct: 122 LLGVAEAGFFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHDALG 181 Query: 182 LHGWQWLFLLEGIPSIVLGVICWIVIDNKIEDARWLKDDEKKLLLARLAAEPKSEAVHSF 241 L GWQW+FL+EG+P ++LGV+ W + E WL D++K LL LA E + + + SF Sbjct: 182 LRGWQWMFLIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQRKTITSF 241 Query: 242 RDALKQPSTITMSLIYLVLASGIYGLVFWMPQLIKTAGTDDTFIIGLITVIPYLCAAIGM 301 P + IY + + + FWMP LI AG IG+++ +PYL M Sbjct: 242 SGIFSNPQVWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYLAGCAFM 301 Query: 302 ILIGRSSDRTGERRWHLAGCALAGAVGYAVSAYFGSNTLVLVVGLSFAATGIIAGIGLFW 361 I IGRSSDR ERRWHL L A G +++A ++ +++ GL A G A + +FW Sbjct: 302 IFIGRSSDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASAALPMFW 361 Query: 362 ILPPRVLTGAAAAGGIALINSVGQLGGIITPYMVGKIRDITGSASLGLYVVALECLVGAA 421 LPP L+ A A GIALI+S G + + PY++G +RD T SASL LY++A+ +GA Sbjct: 362 QLPPAFLSSATLAAGIALISSFGSIAAFLAPYLIGWMRDTTQSASLALYLLAILIALGAG 421 Query: 422 LLL 424 L+L Sbjct: 422 LVL 424